Clinical trials
Atrial Fibrillation Ablation clinical trials
Below are recruiting atrial fibrillation ablation clinical trials, each written for real people, not researchers. We’re tracking 286 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06578104Recruiting
Pulsed AF Study: PulseSelect Catheter for Afib
This study tests a new way to treat atrial fibrillation (Afib) using a special catheter system called PulseSelect that delivers short bursts of energy to create scar tissue in the heart. It is for people whose Afib comes and goes or stays for a while but not more than a year, and who have not had a prior ablation procedure or have a pacemaker or defibrillator.
Tampa, FloridaAges 18 years+ - NCT07236619Recruiting
A new heart procedure for atrial fibrillation
This study tests a new catheter that uses pulsed field energy to isolate the veins in your heart that trigger atrial fibrillation. The goal is to see how long the effects last, and you would need to have a repeat procedure about 2–3 months after the first one.
Rotterdam, South HollandAges 18–80 - NCT05239364Recruiting
Ablation for an abnormal heart rhythm after prior AF surgery
This trial tests a procedure to “ablate” (treat) a specific fast heart rhythm in the upper chambers of the heart that happens after previous atrial fibrillation (AF) ablation or heart surgery. It may help by stopping the rhythm and reducing symptoms, while doctors check how well the targeted mapping and ablation work.
Hamburg, Free and Hanseatic City of HamburgAges 18 years+ - NCT05560204Enrolling by invitation
Atrial fibrillation treatment using pulsed energy and an appendage closure
This trial tests whether combining a pulsed-field ablation (a targeted heart rhythm treatment) with closing off the left atrial appendage can reduce atrial fibrillation risk. It may help people who need rhythm treatment and also want to lower future stroke risk by blocking a common clot-forming spot.
Hong Kong, ShatinAges 19 years+ - NCT07125417RecruitingPhase 4
Blood thinner comparison after left atrial appendage closure
This study compares two approaches after a left atrial appendage closure (LAAC) procedure: taking no blood thinner versus taking just one antiplatelet medication. It aims to see which option is safer for people with atrial fibrillation who are at risk for bleeding.
Nagoya, Aichi-kenAges Any age - NCT06984731Recruiting
Same-day ablation and WATCHMAN closure for AFib
This study tests whether doing a common AFib procedure (radiofrequency ablation) is safe and effective at the same time as closing off the left atrial appendage with the WATCHMAN FLX device. It's for people with nonvalvular atrial fibrillation who are already candidates for both treatments.
Nantong, JiangsuAges 18–80 - NCT07096219Enrolling by invitation
Catheter Ablation for Leaky Mitral Valve in Persistent Atrial Fibrillation
This trial tests if catheter ablation—a procedure to fix heart rhythm—can help people with a leaky mitral valve that is caused by atrial fibrillation (functional mitral regurgitation). If you have persistent atrial fibrillation and moderate leaky valve, you may benefit from this treatment.
Guangzhou, GuangdongAges 18–75 - NCT06220006Recruiting
Comparing heart tissue burns for atrial fibrillation treatment
This study compares two ways to create small burns in the heart tissue to fix an irregular heartbeat (atrial fibrillation). It uses a special MRI to see how well each method works.
Barcelona, CataloniaAges 18 years+ - NCT06542263Recruiting
CPAP for preventing AF recurrence after ablation in people with AF and sleep apnea
This study tests whether using a CPAP machine at night can help prevent atrial fibrillation from coming back after a heart procedure called catheter ablation. It is for people who have both AF and moderate to severe obstructive sleep apnea.
Suzhou, JinagsuAges 18 years+ - NCT07385599Recruiting
Study of a new heart device for atrial fibrillation patients
This trial tests a new device called LAmbre™ II that closes off a part of the heart called the left atrial appendage to help prevent strokes in people with atrial fibrillation who cannot take blood thinners.
ShatinAges 18 years+ - NCT05963698Recruiting
Closing off a heart pouch to prevent stroke
This study tests a procedure that seals off the left atrial appendage (a small heart pouch) to help prevent stroke in people with atrial fibrillation. You may be considered if your stroke risk is high and you are already on blood-thinner medicine.
Birmingham, AlabamaAges 18 years+ - NCT05227053Recruiting
Cryoablation study for paroxysmal atrial fibrillation after approval
This study looks at outcomes after a specific heart procedure called pulmonary vein isolation done with a cryoablation catheter. It is for adults with symptomatic “paroxysmal” atrial fibrillation who are planning this exact procedure.
Anchorage, AlaskaAges 18 years+ - NCT06199180Recruiting
Comparing two ablation methods for repeat atrial fibrillation treatment
This trial tests a newer type of energy (pulsed field ablation) against the standard heat-based method (radiofrequency) for people who have already had one ablation and now have atrial fibrillation again. The goal is to see which works better for keeping your heart in a normal rhythm.
GroningenAges 18–80 - NCT05292209RecruitingPhase 2
RiLuzole pill to reduce atrial fibrillation on heart monitoring
This Phase 2 study tests whether riLuzole can reduce episodes of atrial fibrillation (an irregular heart rhythm) around the time of planned cardioversion. Doctors will monitor your heart using a Holter monitor to count and compare rhythm episodes.
Salt Lake City, UtahAges 18 years+ - NCT05633303Recruiting
Personalized ablation plan for persistent atrial fibrillation
This trial looks at whether tailoring an ablation procedure to you can work better for people with persistent atrial fibrillation. It’s for patients getting their first left atrial ablation and who have had AF for less than 24 months.
LondonAges 18 years+ - NCT07362134Enrolling by invitation
Pulsed-field ablation for recurrent atypical atrial flutter
This study tests a new type of energy called pulsed-field ablation (PFA) to treat a specific kind of irregular heartbeat called atypical atrial flutter that keeps coming back after a prior ablation. It aims to see if this approach can safely stop the abnormal rhythm.
TaipeiAges 18–80 - NCT07308847Recruiting
Study of a new catheter system for treating atrial fibrillation
This trial tests a new catheter and mapping system designed to treat paroxysmal atrial fibrillation (AF), which is a type of irregular heartbeat that comes and goes. If you have this condition, the study aims to see how well the new system works with a minimally invasive procedure.
Jonesboro, ArkansasAges 18–80 - NCT07620262Recruiting
Combined atrial fibrillation treatment and stroke prevention study
This study tests a new approach for people with atrial fibrillation (a type of irregular heartbeat) who are also at high risk for stroke. It combines a procedure to fix the heart's electrical signals with closing off a small pouch in the heart to reduce stroke risk, potentially avoiding long-term blood thinners.
Bay Shore, New YorkAges 18 years+ - NCT06935591Recruiting
AI-guided ablation for hard-to-treat atrial fibrillation
This trial uses an artificial intelligence system (vMap) to find and target abnormal electrical signals outside the pulmonary veins that may be driving atrial fibrillation (AF). The goal is to improve ablation results for people with persistent or recurrent AF.
Jonesboro, ArkansasAges 22 years+ - NCT06529978Recruiting
CoreMap heart mapping for atrial fibrillation ablation
This study tests a new mapping system that helps doctors see the electrical signals in your heart more clearly during a standard ablation for persistent atrial fibrillation. It may improve the accuracy of the treatment.
Naples, FloridaAges 18–80 - NCT06650995Recruiting
Ablation and Exercise for Heart Failure with Normal Pumping
This study tests whether a combination of catheter ablation (a procedure to correct irregular heartbeats) and a structured exercise program can improve symptoms and quality of life in people with diastolic heart failure and a recent onset of persistent atrial fibrillation.
MunichAges 18–99 - NCT07607093Recruiting
Early rhythm control for atrial fibrillation with tricuspid valve leakage
This trial tests whether treating atrial fibrillation (an irregular heartbeat) early helps patients who also have tricuspid regurgitation (leakage in a heart valve). Researchers want to see if controlling the heart rhythm early can improve outcomes for people with both conditions.
Seoul, SeoulAges Any age - NCT05841056RecruitingPhase 3
Short amiodarone treatment to prevent new heart rhythm after surgery
This trial studies whether a short course of amiodarone started right after heart surgery can reduce problems from new-onset atrial fibrillation (a common fast heart rhythm) or flutter. It may help some patients avoid ongoing rhythm issues and improve recovery soon after discharge.
Hamilton, OntarioAges 18 years+ - NCT04964765Recruiting
3D heart mapping after early irregular heartbeat after surgery
This study uses 3D heart mapping to understand a specific kind of irregular heartbeat that can happen soon after cardiac surgery. It may help doctors better recognize what’s happening in the heart during the early recovery period.
Sankt PöltenAges 18 years+
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Common questions
- Are there clinical trials for atrial fibrillation ablation?
- Yes. Clin2 currently lists 286 recruiting atrial fibrillation ablation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a atrial fibrillation ablation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a atrial fibrillation ablation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.