Clinical trials
Atrial Fibrillation Ablation clinical trials
Below are recruiting atrial fibrillation ablation clinical trials, each written for real people, not researchers. We’re tracking 291 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06650995Recruiting
Ablation and Exercise for Heart Failure with Normal Pumping
This study tests whether a combination of catheter ablation (a procedure to correct irregular heartbeats) and a structured exercise program can improve symptoms and quality of life in people with diastolic heart failure and a recent onset of persistent atrial fibrillation.
MunichAges 18–99 - NCT07607093Recruiting
Early rhythm control for atrial fibrillation with tricuspid valve leakage
This trial tests whether treating atrial fibrillation (an irregular heartbeat) early helps patients who also have tricuspid regurgitation (leakage in a heart valve). Researchers want to see if controlling the heart rhythm early can improve outcomes for people with both conditions.
Seoul, SeoulAges Any age - NCT07671677Recruiting
BodyGuardian monitoring after AF ablation
This study tests using a portable heart monitor called BodyGuardian to check for atrial fibrillation returning after a procedure called ablation. It may help your doctor find irregular heartbeats early.
Delray Beach, FloridaAges 18 years+ - NCT05841056RecruitingPhase 3
Short amiodarone treatment to prevent new heart rhythm after surgery
This trial studies whether a short course of amiodarone started right after heart surgery can reduce problems from new-onset atrial fibrillation (a common fast heart rhythm) or flutter. It may help some patients avoid ongoing rhythm issues and improve recovery soon after discharge.
Hamilton, OntarioAges 18 years+ - NCT04964765Recruiting
3D heart mapping after early irregular heartbeat after surgery
This study uses 3D heart mapping to understand a specific kind of irregular heartbeat that can happen soon after cardiac surgery. It may help doctors better recognize what’s happening in the heart during the early recovery period.
Sankt PöltenAges 18 years+ - NCT05048004Recruiting
Test of a heart procedure during atrial fibrillation ablation
This trial studies whether adding a specific technique during a first-time catheter ablation for atrial fibrillation can improve safety or outcomes. It may help doctors understand risks related to small blood clots during the procedure.
BerlinAges 18 years+ - NCT05264831Recruiting
Ablation treatment after failed electric heart shock
This trial tests whether blocking faulty heart signals from the pulmonary veins (with or without additional “substrate” modification) works better when electric cardioversion doesn’t stop persistent atrial fibrillation. It may help people who remain in atrial fibrillation after cardioversion by reducing symptoms and abnormal rhythm over time.
Caluire-et-CuireAges 18–80 - NCT05353140Recruiting
Left atrial appendage device vs blood thinners after stent
This trial compares a heart device that can help prevent blood clots in the heart (called LAAO) versus long-term blood thinners for people who have atrial fibrillation and recently had a stent placed. It aims to see which approach better prevents stroke and related blood-clot problems while keeping side effects manageable.
Xi'an, ShannxiAges 18 years+ - NCT06061120Recruiting
Heart rhythm study for ablation patients
This study uses a special ECG to better tell apart different types of fast heart rhythms in people scheduled for a procedure called ablation. The goal is to improve diagnosis and treatment for conditions like atrial fibrillation and other supraventricular tachycardias.
Aachen, North Rhine-WestphaliaAges 18 years+ - NCT06065124Recruiting
Study on weight loss surgery for heart failure with irregular heartbeat
This trial tests if weight loss surgery can help people with heart failure and atrial fibrillation (an irregular heartbeat) improve their heart condition. You may join if you are between 45 and 70, have a BMI of 32 to 40, and have mild to moderate heart failure with preserved pumping function.
Arnhem, GelderlandAges 45–70 - NCT06445439Recruiting
Finding the Best Pacemaker Rate for Heart Failure
This study tests whether adjusting the pacing rate on a special pacemaker (CRT or conduction system pacing) can improve heart function and daily symptoms in people with atrial fibrillation and heart failure.
Washington D.C., District of ColumbiaAges 18–90 - NCT06552845Recruiting
Heart scan to guide atrial fibrillation treatment
This trial uses a special MRI scan to see if heart scarring matches low-voltage areas detected during catheter ablation for atrial fibrillation. If the scan results are consistent, it could help doctors better plan ablation procedures.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06575881Recruiting
Genetic heart muscle disease and heart rhythm study
This study looks at the risk of a fast heart rhythm (ventricular tachycardia) in people with genetic heart muscle diseases. It tests whether having a specific genetic change affects the success of a heart ablation procedure.
Nashville, TennesseeAges 18 years+ - NCT06657404Recruiting
Modified 'Pills-in-the-Pocket' strategy for AF after ablation
This study tests a modified 'pills-in-the-pocket' approach—taking antiarrhythmic drugs only when symptoms occur—for people with non-valvular atrial fibrillation (AF) who still have arrhythmias lasting over 24 hours after their first catheter ablation. It aims to see if this strategy can safely control symptoms without needing daily medication.
Guangzhou, GuangdongAges 18 years+ - NCT06730828RecruitingPhase 1/Phase 2
Amiodarone patch to prevent new irregular heartbeat after heart surgery
This trial tests a patch that releases amiodarone, a medicine that helps prevent a common irregular heartbeat after open-heart surgery. The patch is placed on the heart during surgery to stop new atrial fibrillation from starting.
Louisville, KentuckyAges 20–85 - NCT07087587Recruiting
Sleep apnea treatment for AFib: a personalized trial
This study tests whether treating sleep apnea with a CPAP machine can reduce the number of AFib episodes you have. It's a personalized 'N-of-1' trial, meaning you'll try both CPAP and no CPAP at different times to see what works best for you.
Cleveland, OhioAges 18–85 - NCT07122947Recruiting
Apple Watch to detect AFib after heart surgery
This study tests if an Apple Watch can help detect when atrial fibrillation (an irregular heartbeat) comes back after heart surgery. You'll wear an Apple Watch and a small skin patch (Zio Patch) to track your heart rhythm.
St Louis, MissouriAges 22 years+ - NCT07129564Recruiting
Stepwise treatment for persistent atrial fibrillation
This study tests a stepwise treatment plan for people with persistent atrial fibrillation (a long-lasting irregular heartbeat) who also have an enlarged left atrium. It aims to see if a medication called amiodarone plus a cardioversion procedure can help restore normal rhythm.
ChongqingAges 18–70 - NCT07174206Recruiting
Smartwatch monitoring for heart patients
This trial tests a smartwatch tool to track heart rhythm and detect problems in people with heart disease. It may help find irregular heartbeats early during routine checkups.
São Paulo, São PauloAges 22 years+ - NCT07250529Recruiting
Comparing two pacemaker pacing methods for heart block
This study compares two types of pacemaker pacing methods in people with heart block and normal heart pumping function. It looks at how often short bursts of fast heart rhythm occur in the upper heart chambers, which may help improve long-term heart health.
PátraiAges 18 years+ - NCT05136131Recruiting
Quality-of-life support after cardioversion for persistent AF
This study looks at how a heart rhythm procedure (cardioversion) affects quality of life in people with persistent atrial fibrillation (AF). It may help you understand whether a specific approach can improve day-to-day symptoms and well-being after treatment.
Newmarket, OntarioAges 18 years+ - NCT07414121Recruiting
Vascular closure vs manual compression after AF ablation
This study compares two methods to close the blood vessel after a catheter ablation for atrial fibrillation (AF). It may help reduce bleeding or other problems at the access site.
HamburgAges 18–95 - NCT07421076Recruiting
Grid mapping study for atrial fibrillation ablation
This trial tests a new mapping tool to help doctors find and treat the source of atrial fibrillation (AF) during a standard ablation procedure. It may offer a more precise way to guide treatment for people with AF that comes and goes.
Jinan, ShandongAges 18 years+ - NCT07439016Recruiting
LA function after pulse field ablation for paroxysmal AF
This trial tests how pulse field ablation (a treatment that uses short electrical pulses to correct irregular heartbeats) affects the left atrium's function in people with paroxysmal atrial fibrillation (AFib that comes and goes). It may help if you have paroxysmal AFib and are in normal rhythm at the start of the procedure.
PragueAges 18 years+
Hear when a new Atrial Fibrillation Ablation trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for atrial fibrillation ablation?
- Yes. Clin2 currently lists 291 recruiting atrial fibrillation ablation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a atrial fibrillation ablation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a atrial fibrillation ablation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.