Clinical trials
Atrial Fibrillation Ablation clinical trials
Below are recruiting atrial fibrillation ablation clinical trials, each written for real people, not researchers. We’re tracking 291 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06650995Recruiting
Ablation and Exercise for Heart Failure with Normal Pumping
This study tests whether a combination of catheter ablation (a procedure to correct irregular heartbeats) and a structured exercise program can improve symptoms and quality of life in people with diastolic heart failure and a recent onset of persistent atrial fibrillation.
MunichAges 18–99 - NCT07607093Recruiting
Early rhythm control for atrial fibrillation with tricuspid valve leakage
This trial tests whether treating atrial fibrillation (an irregular heartbeat) early helps patients who also have tricuspid regurgitation (leakage in a heart valve). Researchers want to see if controlling the heart rhythm early can improve outcomes for people with both conditions.
Seoul, SeoulAges Any age - NCT07287436Recruiting
Watchman device to prevent stroke in atrial fibrillation
This trial tests a device called the WATCHMAN Elite, which is placed in a small pouch of the heart to close it and reduce stroke risk, potentially allowing patients to stop blood thinners. It is for people with atrial fibrillation who cannot or prefer not to take long-term blood thinners.
Jonesboro, ArkansasAges 18 years+ - NCT05264831Recruiting
Ablation treatment after failed electric heart shock
This trial tests whether blocking faulty heart signals from the pulmonary veins (with or without additional “substrate” modification) works better when electric cardioversion doesn’t stop persistent atrial fibrillation. It may help people who remain in atrial fibrillation after cardioversion by reducing symptoms and abnormal rhythm over time.
Caluire-et-CuireAges 18–80 - NCT07816029Recruiting
Closing a heart pouch to prevent stroke in atrial fibrillation
This study tests a device and procedure to close off a small pouch in the heart (left atrial appendage) where blood clots can form in people with atrial fibrillation. The goal is to reduce the risk of stroke, possibly lowering the need for long-term blood thinners.
PragueAges 18 years+ - NCT07806890Recruiting
New 4D ultrasound imaging during left atrial appendage closure
This study tests a new 3D/4D ultrasound technology that creates detailed images of the heart during a left atrial appendage closure procedure. The goal is to see if this imaging tool helps doctors perform the procedure more safely and accurately.
Cleveland, OhioAges 18 years+ - NCT06657404Recruiting
Modified 'Pills-in-the-Pocket' strategy for AF after ablation
This study tests a modified 'pills-in-the-pocket' approach—taking antiarrhythmic drugs only when symptoms occur—for people with non-valvular atrial fibrillation (AF) who still have arrhythmias lasting over 24 hours after their first catheter ablation. It aims to see if this strategy can safely control symptoms without needing daily medication.
Guangzhou, GuangdongAges 18 years+ - NCT07671677Recruiting
BodyGuardian monitoring after AF ablation
This study tests using a portable heart monitor called BodyGuardian to check for atrial fibrillation returning after a procedure called ablation. It may help your doctor find irregular heartbeats early.
Delray Beach, FloridaAges 18 years+ - NCT07645066Recruiting
Heart Pacemaker Placement to Prevent Irregular Heartbeat
This trial tests a new pacemaker placement technique for people with a slow heartbeat (sinus node dysfunction) who need a pacemaker anyway. The goal is to see if this special placement can help prevent atrial fibrillation, a type of irregular heartbeat that can cause stroke and other complications.
Anqing, AnhuiAges 18 years+ - NCT07574697Recruiting
Genetic Study of Atrial Fibrillation and Heart Function Recovery
This study looks at genetic factors in people with atrial fibrillation (an irregular heartbeat) and weak heart function to understand why some people's hearts recover after treatment and others don't. Researchers will collect blood samples and medical information to identify genetic patterns.
LondonAges 18 years+ - NCT06730828RecruitingPhase 1/Phase 2
Amiodarone patch to prevent new irregular heartbeat after heart surgery
This trial tests a patch that releases amiodarone, a medicine that helps prevent a common irregular heartbeat after open-heart surgery. The patch is placed on the heart during surgery to stop new atrial fibrillation from starting.
Louisville, KentuckyAges 20–85 - NCT07515040Recruiting
AccuSafe guidewire versus needle for heart rhythm procedure
This trial compares two different tools used during a minimally invasive heart procedure to treat atrial fibrillation (an irregular heartbeat). The study tests whether a newer guidewire tool is safer and works as well as the traditional needle approach.
Nanchang, JiangxiAges 18–75 - NCT07462910Recruiting
Checking diaphragm nerve function after pulsed field ablation
This study looks at how a new type of catheter ablation (pulsed field ablation) for atrial fibrillation affects the phrenic nerve, which controls the diaphragm. Researchers will use X-rays to see if the treatment causes any temporary diaphragm problems.
MontrealAges 18 years+ - NCT07439016Recruiting
LA function after pulse field ablation for paroxysmal AF
This trial tests how pulse field ablation (a treatment that uses short electrical pulses to correct irregular heartbeats) affects the left atrium's function in people with paroxysmal atrial fibrillation (AFib that comes and goes). It may help if you have paroxysmal AFib and are in normal rhythm at the start of the procedure.
PragueAges 18 years+ - NCT07421076Recruiting
Grid mapping study for atrial fibrillation ablation
This trial tests a new mapping tool to help doctors find and treat the source of atrial fibrillation (AF) during a standard ablation procedure. It may offer a more precise way to guide treatment for people with AF that comes and goes.
Jinan, ShandongAges 18 years+ - NCT07414121Recruiting
Vascular closure vs manual compression after AF ablation
This study compares two methods to close the blood vessel after a catheter ablation for atrial fibrillation (AF). It may help reduce bleeding or other problems at the access site.
HamburgAges 18–95 - NCT05353140Recruiting
Left atrial appendage device vs blood thinners after stent
This trial compares a heart device that can help prevent blood clots in the heart (called LAAO) versus long-term blood thinners for people who have atrial fibrillation and recently had a stent placed. It aims to see which approach better prevents stroke and related blood-clot problems while keeping side effects manageable.
Xi'an, ShannxiAges 18 years+ - NCT07250529Recruiting
Comparing two pacemaker pacing methods for heart block
This study compares two types of pacemaker pacing methods in people with heart block and normal heart pumping function. It looks at how often short bursts of fast heart rhythm occur in the upper heart chambers, which may help improve long-term heart health.
PátraiAges 18 years+ - NCT06065124Recruiting
Study on weight loss surgery for heart failure with irregular heartbeat
This trial tests if weight loss surgery can help people with heart failure and atrial fibrillation (an irregular heartbeat) improve their heart condition. You may join if you are between 45 and 70, have a BMI of 32 to 40, and have mild to moderate heart failure with preserved pumping function.
Arnhem, GelderlandAges 45–70 - NCT04964765Recruiting
3D heart mapping after early irregular heartbeat after surgery
This study uses 3D heart mapping to understand a specific kind of irregular heartbeat that can happen soon after cardiac surgery. It may help doctors better recognize what’s happening in the heart during the early recovery period.
Sankt PöltenAges 18 years+ - NCT07174206Recruiting
Smartwatch monitoring for heart patients
This trial tests a smartwatch tool to track heart rhythm and detect problems in people with heart disease. It may help find irregular heartbeats early during routine checkups.
São Paulo, São PauloAges 22 years+ - NCT07129564Recruiting
Stepwise treatment for persistent atrial fibrillation
This study tests a stepwise treatment plan for people with persistent atrial fibrillation (a long-lasting irregular heartbeat) who also have an enlarged left atrium. It aims to see if a medication called amiodarone plus a cardioversion procedure can help restore normal rhythm.
ChongqingAges 18–70 - NCT07122947Recruiting
Apple Watch to detect AFib after heart surgery
This study tests if an Apple Watch can help detect when atrial fibrillation (an irregular heartbeat) comes back after heart surgery. You'll wear an Apple Watch and a small skin patch (Zio Patch) to track your heart rhythm.
St Louis, MissouriAges 22 years+ - NCT07087587Recruiting
Sleep apnea treatment for AFib: a personalized trial
This study tests whether treating sleep apnea with a CPAP machine can reduce the number of AFib episodes you have. It's a personalized 'N-of-1' trial, meaning you'll try both CPAP and no CPAP at different times to see what works best for you.
Cleveland, OhioAges 18–85
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Common questions
- Are there clinical trials for atrial fibrillation ablation?
- Yes. Clin2 currently lists 291 recruiting atrial fibrillation ablation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a atrial fibrillation ablation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a atrial fibrillation ablation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.