Clinical trials
Atrial Fibrillation Ablation clinical trials
Below are recruiting atrial fibrillation ablation clinical trials, each written for real people, not researchers. We’re tracking 287 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05504356Recruiting
Study to improve atrial fibrillation ablation and new therapies
This study looks at what results from atrial fibrillation ablation (a heart rhythm procedure) and newer related therapies. If you recently had the procedure—or are scheduled for it soon—you may use an app and website to share information that helps researchers compare outcomes and improve care.
San Francisco, CaliforniaAges 18 years+ - NCT05508256RecruitingPhase 4
Ablation for atrial fibrillation in heart failure with preserved function
This trial tests whether a catheter procedure that treats atrial fibrillation works better than standard care for people with heart failure with preserved ejection fraction. It aims to improve heart rhythm symptoms and overall outcomes compared with conventional treatment.
BerlinAges 18 years+ - NCT05539040Recruiting
Testing why certain heart signals trigger atrial fibrillation
This trial studies abnormal electrical signals in the right upper heart chamber and how they relate to atrial fibrillation (AF). It may help improve how doctors target AF treatment during catheter ablation for people who have AF symptoms.
LondonAges 18–85 - NCT05557526Recruiting
Improving quality of life after atrial fibrillation ablation
This study aims to improve how patients feel in daily life after a procedure to treat atrial fibrillation (an irregular heartbeat). It focuses on whether better patient expectations and support can lead to a better quality of life after the procedure.
Düsseldorf, North Rhine-WestfaliaAges 18 years+ - NCT05610215Recruiting
Hybrid or catheter ablation for atrial fibrillation in hypertrophic heart
This trial compares two procedures to treat atrial fibrillation (an irregular heartbeat) in people who also have hypertrophic cardiomyopathy (thickened heart muscle). It looks at whether the hybrid approach or a catheter-based approach works better for controlling symptoms and heart rhythm.
BeijingAges 18 years+ - NCT05638841Recruiting
Study of repeat atrial fibrillation risk after ablation
This study follows adults who have had a procedure to treat an irregular heartbeat, to understand who is more likely to have it return. It may help doctors predict risk and plan follow-up after the procedure.
BeijingAges 18 years+ - NCT05717725RecruitingPhase 3
Pulsed heart ablation vs fake procedure for irregular heartbeat
This trial tests whether pulsed-field ablation (a targeted treatment meant to stop abnormal heart signals) works better than a sham, or “placebo,” ablation. It is for certain people with atrial fibrillation (AF) to see if symptoms and heart rhythm outcomes improve.
PragueAges 18 years+ - NCT05776797Recruiting
Ablation vs best medicines for CRT patients with permanent atrial fibrillation
This trial compares two approaches—an AV junction ablation procedure versus continued best medical treatment—in people who already have a heart device for heart failure (CRT) but still have ongoing permanent atrial fibrillation. It aims to improve how well your heart rhythm is controlled and how effectively the device can pace your heart.
Liberec, Liberec RegionAges 18–85 - NCT05790707Recruiting
Ablation for persistent atrial fibrillation to help memory
This study checks whether a procedure called atrial fibrillation ablation can slow memory problems in people who already have mild cognitive impairment. Participants will be tested on thinking and memory before and after treatment to see if the procedure helps.
AngersAges 60–80 - NCT05794386Recruiting
Ablation plan guided by left-heart scar map for persistent atrial fibrillation
This study tests whether using a 3D heart “scar map” helps doctors choose a better catheter ablation strategy for people with persistent atrial fibrillation (AF). It may help reduce ongoing AF by targeting the scar area in the left atrium.
Seoul, Jongno-guAges 19 years+ - NCT05836987RecruitingPhase 3
Smartwatch monitoring trial to guide blood thinner use for AF
This study tests whether continuous heart-rhythm monitoring with a smartwatch can better guide treatment for atrial fibrillation (AF) while you stay on a blood thinner. The goal is to improve safety and reduce stroke risk by catching AF patterns more closely.
Phoenix, ArizonaAges 22–85 - NCT05844501RecruitingPhase 4
Ondansetron before heart ablation for atrial fibrillation
This trial tests whether ondansetron can help people with atrial fibrillation (an abnormal heart rhythm) around the time of elective catheter ablation. It may improve the safety or effectiveness of the procedure by targeting a pathway involved in heart rhythm events.
Indianapolis, IndianaAges 18–100 - NCT05908955Recruiting
Atrial fibrillation ablation with extra vein targeting
This trial studies a modified ablation procedure that targets the superior vena cava in addition to the pulmonary veins to help stop episodes of paroxysmal (coming and going) atrial fibrillation. It may help people whose symptoms continue despite antiarrhythmic medicines.
Beijing, Beijing MunicipalityAges 40–75 - NCT05961865Recruiting
Study of inflammation during catheter ablation for atrial fibrillation
This study measures changes in inflammation in people with atrial fibrillation (AF) who are getting a catheter ablation procedure. It may help doctors better understand what happens in the body during the procedure and why some patients do better than others.
MilanAges 18–85 - NCT05978388Recruiting
CT scan before catheter ablation for atrial fibrillation
This trial is testing whether a coronary CT angiography scan, performed before catheter ablation for atrial fibrillation, helps doctors find hidden blockages in heart arteries. It may help people without known heart disease avoid unnecessary procedures.
Hellerup, Capital RegionAges 18 years+ - NCT05996159Recruiting
Using very high power for short duration to treat atrial fibrillation
This study tests a new way to perform a common procedure (pulmonary vein isolation) for people with paroxysmal atrial fibrillation. Instead of using the standard amount of energy for a longer time, this method uses a very high amount of energy for a very short time. This might make the procedure faster and just as safe.
SeoulAges 19 years+ - NCT06023888Recruiting
Heart rhythm analysis for persistent atrial fibrillation
This study tests a new way to analyze heart signals in people with long-standing atrial fibrillation that hasn't gotten better with medication. It may help doctors understand your heart rhythm better and guide future treatments.
TaipeiAges 20–80 - NCT06056271Recruiting
Tracking AI use during AF ablation in real-world care
This trial is for people with atrial fibrillation (AF) who are having or recently had a catheter ablation procedure. It looks at how using a special artificial intelligence tool, called VX1, during the procedure affects patient outcomes.
Evanston, IllinoisAges 21 years+ - NCT06078735Recruiting
Device vs manual pressure for closing blood vessels after AFib procedure
This study compares two ways to close the vein entry after heart ablation for AFib: the LockeT device versus manual compression. It helps find which method works better.
Overland Park, KansasAges 18 years+ - NCT06108414RecruitingPhase 4
Low-dose vs standard-dose blood thinner for older adults with atrial fibrillation
This trial tests whether a lower dose of the blood thinner rivaroxaban works as well as the standard dose for people 70 and older with atrial fibrillation (an irregular heartbeat). The goal is to find the safest dose to prevent strokes while reducing bleeding risks.
Beijing, Beijing MunicipalityAges 70 years+ - NCT06125925Recruiting
Ablation for AFib in patients with heart failure and preserved ejection fraction
This study tests whether a catheter ablation procedure can help people with atrial fibrillation and a kind of heart failure where the heart pumps normally but doesn't relax properly (HFpEF). It looks at whether the procedure can improve symptoms and heart function.
NanjingAges 18–80 - NCT06145906Recruiting
Optimizing catheter ablation for atrial fibrillation
This trial is studying a way to improve the entire process of catheter ablation for atrial fibrillation. It may help people who are having this procedure for the first time and have a normal-sized left atrium and good heart function.
Zhengzhou, HenanAges 18–80 - NCT06157437Recruiting
Focal pulse ablation for atrial flutter
This study tests a new device that uses focused pulses of energy to treat a common type of fast heartbeat called typical atrial flutter. It aims to see if this approach is safe and effective for people who have had at least one episode in the past 6 months.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06165510Recruiting
Convergent ablation and left atrial appendage isolation for persistent AF
This trial tests a two-step procedure for persistent atrial fibrillation that combines a heart ablation with isolation of a small heart pouch. It aims to see if this approach is more effective than standard care.
LondonAges 18–80
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Common questions
- Are there clinical trials for atrial fibrillation ablation?
- Yes. Clin2 currently lists 287 recruiting atrial fibrillation ablation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a atrial fibrillation ablation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a atrial fibrillation ablation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.