Clinical trials
Atrial Fibrillation and Flutter clinical trials
Below are recruiting atrial fibrillation and flutter clinical trials, each written for real people, not researchers. We’re tracking 90 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07210151Recruiting
Imaging Catheter for Heart Ablation Procedures
This study tests a new imaging catheter (VERAFEYE) to help doctors guide ablation procedures for atrial flutter or atrial fibrillation. It may lead to safer, more precise treatment of these heart rhythm problems.
SplitAges 18 years+ - NCT07196176Recruiting
Heart rhythm test registry at University Hospital Düsseldorf
This registry collects information from people who have had or are scheduled to have a heart rhythm test or a procedure to restore a normal heartbeat at University Hospital Düsseldorf. It helps doctors understand more about heart rhythm problems and treatments over time.
DüsseldorfAges 18 years+ - NCT07171463Recruiting
New ablation for paroxysmal atrial fibrillation
This trial tests a new treatment that uses two types of energy (pulsed field and radiofrequency) to fix the heart's electrical signals in people with paroxysmal atrial fibrillation (AFib that comes and goes). It aims to be more effective and safer than standard ablation alone.
Rzeszów, Podkarpackie VoivodeshipAges 18 years+ - NCT07141745Recruiting
Comparing energy types for repeat atrial fibrillation treatment
This trial compares two different energy methods (electroporation vs radiofrequency ablation) guided by 3D imaging for people who have had a prior ablation for atrial fibrillation but still have recurrences. It aims to find which method is safer and more effective for repeat procedures.
WroclawAges 18–85 - NCT07109141Recruiting
Registry of Heart Rhythm Fix Procedures Using Pulsed Field Ablation in Poland
This study tracks people who have a procedure called pulsed field ablation to fix an abnormal heart rhythm (atrial arrhythmia). It's a registry, meaning researchers will collect information to learn more about how well the treatment works and how safe it is.
Wroclaw, Lower Silesian VoivodeshipAges 18 years+ - NCT07002450Recruiting
CT scan to check for clots before heart shock therapy
This trial uses a CT scan of the left atrium to check for blood clots before a procedure called cardioversion (an electric shock to restore normal heart rhythm). The goal is to see if the CT scan can safely replace other imaging methods in the emergency department, helping to speed up treatment.
Hershey, PennsylvaniaAges 18 years+ - NCT06989775Recruiting
BoxX-NoAF Trial: Preventing Stroke During Heart Surgery
This trial tests a device to close a small pouch in the heart during planned bypass surgery, to help prevent future strokes. It is for people who have never had an irregular heartbeat and are at higher stroke risk due to age and other factors.
Scottsdale, ArizonaAges 65 years+ - NCT06871228Recruiting
Stopping blood thinners after successful AF ablation with close heart monitoring
This trial tests whether people with atrial fibrillation who have had a successful ablation procedure can safely stop taking blood thinners (NOACs) if they wear a monitor to check for any silent heart rhythm problems. It may help you avoid the risks of long-term blood thinner use if your ablation has been effective.
Hefei, AnhuiAges 18–80 - NCT06486636Recruiting
Pericardiotomy in heart surgery
This trial tests whether opening the sac around the heart (pericardiotomy) during certain heart surgeries can help prevent future heart rhythm problems. It may be an option for people having surgery on the main artery from the heart, heart valves, or heart arteries.
New York, New YorkAges 18 years+ - NCT02347111RecruitingPhase 4
Genetic study to guide antiarrhythmic drugs for atrial fibrillation
This study looks at how a person’s genetics may affect how well and safely antiarrhythmic medicines work for atrial fibrillation (AF). If you join, you may get medicine options like flecainide or sotalol, and researchers compare outcomes to genetic information.
Chicago, IllinoisAges 18–100 - NCT06376916RecruitingPhase 3
Testing magnesium doses for fast heart rate in atrial fibrillation
This trial tests whether giving a higher dose of magnesium (4 grams) compared to a lower dose (2 grams) or a placebo can help control a fast heart rate during atrial fibrillation. It may help patients who are already receiving diltiazem.
Oak Lawn, IllinoisAges 18 years+ - NCT06263608Recruiting
Sleep apnea testing and treatment for atrial fibrillation patients
This study tests a new way to check and treat sleep apnea in people with atrial fibrillation (AF). If you have AF and symptoms, you may be able to join and get sleep tracking and treatment that could help both your heart and sleep.
EdegemAges 18 years+ - NCT05997914Enrolling by invitation
Storytelling to reduce stroke risk in African Americans with atrial fibrillation
This study tests whether a storytelling program can help African American patients with atrial fibrillation start taking blood thinners as recommended by their doctor. The goal is to reduce stroke risk and improve health outcomes.
Jacksonville, FloridaAges 18 years+ - NCT05411614Recruiting
Testing two heart procedures for atrial fibrillation in heart failure
This study compares two different ablation procedures (treatments that target heart rhythm triggers) for people with atrial fibrillation and reduced heart pumping. It aims to see which approach works best and is safest for improving your heart rhythm when you also have heart failure.
ChertseyAges 18 years+ - NCT05844501RecruitingPhase 4
Ondansetron before heart ablation for atrial fibrillation
This trial tests whether ondansetron can help people with atrial fibrillation (an abnormal heart rhythm) around the time of elective catheter ablation. It may improve the safety or effectiveness of the procedure by targeting a pathway involved in heart rhythm events.
Indianapolis, IndianaAges 18–100 - NCT05836987RecruitingPhase 3
Smartwatch-guided blood thinners for intermittent atrial fibrillation
This study tests whether using a smartwatch to monitor your heartbeat can safely guide when to take blood thinners. If you have intermittent atrial fibrillation, you may be able to avoid taking blood thinners when your heart rhythm is normal.
Phoenix, ArizonaAges 22–85 - NCT05790707Recruiting
Ablation for persistent atrial fibrillation to help memory
This study checks whether a procedure called atrial fibrillation ablation can slow memory problems in people who already have mild cognitive impairment. Participants will be tested on thinking and memory before and after treatment to see if the procedure helps.
AngersAges 60–80 - NCT05511389Recruiting
Testing better electrode placement for heart rhythm shock
This study tests whether two different positions of the electrodes (pads) used for an electrical shock work equally well for people with atrial fibrillation or flutter. It may help improve how safely and effectively the shock restores a normal rhythm.
Hamilton, OntarioAges 18 years+ - NCT05014802Recruiting
MRI scans before heart surgery to predict post-surgery atrial fibrillation
This study uses an MRI scan before heart surgery to look for heart scarring that may predict who will develop atrial fibrillation afterward. Knowing the risk ahead of time could help doctors monitor you more closely and plan prevention.
Covington, LouisianaAges 40–120 - NCT04298723Recruiting
Left atrial appendage closure vs blood thinners after brain bleed
This trial compares a procedure that blocks a heart blood-choke point (the left atrial appendage) versus taking blood thinners by mouth. It is for people with atrial fibrillation who have had a brain bleed and may be safer avoiding long-term blood thinners.
Mannheim, Baden-WurttembergAges 18 years+ - NCT04267159Recruiting
Treatment plan for sudden irregular heartbeat in the ER
This trial looks at how to manage a new, sudden irregular heartbeat (atrial fibrillation or atrial flutter) when you first arrive in the emergency room. It may help by testing an “elective” approach to rhythm control, depending on your heart rate and overall safety factors.
Jyväskylä, Central FinlandAges Any age - NCT03868150RecruitingPhase 4
Preventing an abnormal heart rhythm after heart surgery
This trial studies whether giving a medication (amiodarone) during and after certain heart surgeries can help prevent atrial fibrillation, an irregular heartbeat that can happen after surgery. It may help by aiming to stop this rhythm problem before it starts.
Stanford, CaliforniaAges 18 years+ - NCT03862859RecruitingPhase 4
Warfarin safety for people with atrial fibrillation on dialysis
This trial studies whether the blood thinner warfarin is safe and effective for preventing stroke and blood clots in people who have atrial fibrillation and need long-term dialysis. It may help your care team better balance clot prevention against bleeding risk.
Herlev, HerlevAges 18 years+ - NCT07649109RecruitingPhase 4
Heart Device Detected Irregular Heartbeats: Treatment Study
This study follows patients who have a heart rhythm device (pacemaker, defibrillator, or resynchronization device) and have experienced brief episodes of fast irregular heartbeats detected by the device. The study compares treatment approaches to understand which helps patients stay healthier and feel better.
TaipeiAges 18 years+
Hear when a new Atrial Fibrillation and Flutter trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for atrial fibrillation and flutter?
- Yes. Clin2 currently lists 90 recruiting atrial fibrillation and flutter studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a atrial fibrillation and flutter trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a atrial fibrillation and flutter trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.