Clinical trials
Atrial Fibrillation, Paroxysmal or Persistent clinical trials
Below are recruiting atrial fibrillation, paroxysmal or persistent clinical trials, each written for real people, not researchers. We’re tracking 469 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04005508Recruiting
Study sleep apnea and heart outcomes in high-risk atrial fibrillation
This trial looks at how obstructive sleep apnea (OSA, a breathing problem during sleep) relates to heart outcomes in people with atrial fibrillation (AF). It may help doctors better predict risk and choose safer care for people who are high cardiovascular risk.
SingaporeAges 22–99 - NCT04628078Recruiting
Echocardiogram-guided heart procedure registry for atrial fibrillation
This study keeps a real-world record of people with atrial fibrillation who are planning a procedure to close off the heart’s left atrial appendage. Doctors use echocardiography (heart ultrasound) to guide the closure and track outcomes to improve care.
BernAges 18 years+ - NCT04695106RecruitingPhase 4
Blood Thinner and Heart Attack Prevention Study
This study tests whether taking dabigatran (a blood thinner) combined with ticagrelor (a blood clot preventer) is safe and effective for patients with irregular heart rhythm (atrial fibrillation) who recently had a heart attack and received a stent. The goal is to prevent future blood clots while minimizing bleeding risks.
Gdansk, Pomeranian VoivodeshipAges 18 years+ - NCT07429214Recruiting
Study of a new catheter for atrial fibrillation ablation
This trial tests a new catheter system to treat atrial fibrillation (AF) by creating small scars in the heart to block faulty signals. It may help people with symptoms that continue despite medication and who are scheduled for a standard ablation procedure.
AalstAges 18–75 - NCT05432024Recruiting
Heart MRI checks how well ablation lesions form
This study uses a special heart MRI to look at how ablation creates scar tissue in people with atrial fibrillation. It may help doctors improve how ablation is done and understand which technique works best.
NieuwegeinAges 18 years+ - NCT05717725RecruitingPhase 3
Pulsed heart ablation vs fake procedure for irregular heartbeat
This trial tests whether pulsed-field ablation (a targeted treatment meant to stop abnormal heart signals) works better than a sham, or “placebo,” ablation. It is for certain people with atrial fibrillation (AF) to see if symptoms and heart rhythm outcomes improve.
PragueAges 18 years+ - NCT05773768Recruiting
Care pathway study for newly diagnosed atrial fibrillation patients
This study looks at new care plans (“care pathways”) and how well they work, including cost and health outcomes. It may help by comparing whether a different follow-up approach after a new atrial fibrillation diagnosis leads to better care, especially for older adults.
GroningenAges 65 years+ - NCT06065124Recruiting
Study on weight loss surgery for heart failure with irregular heartbeat
This trial tests if weight loss surgery can help people with heart failure and atrial fibrillation (an irregular heartbeat) improve their heart condition. You may join if you are between 45 and 70, have a BMI of 32 to 40, and have mild to moderate heart failure with preserved pumping function.
Arnhem, GelderlandAges 45–70 - NCT06220006Recruiting
Comparing heart tissue burns for atrial fibrillation treatment
This study compares two ways to create small burns in the heart tissue to fix an irregular heartbeat (atrial fibrillation). It uses a special MRI to see how well each method works.
Barcelona, CataloniaAges 18 years+ - NCT06253000Recruiting
Heat vs. Freezing for the Back of the Heart
This trial tests two ways to treat the back wall of the heart's left chamber in people with stubborn atrial fibrillation. It compares radiofrequency (heat) and cryoablation (freezing) to see which is safer and works better.
MoscowAges 18–80 - NCT06542263Recruiting
CPAP for preventing AF recurrence after ablation in people with AF and sleep apnea
This study tests whether using a CPAP machine at night can help prevent atrial fibrillation from coming back after a heart procedure called catheter ablation. It is for people who have both AF and moderate to severe obstructive sleep apnea.
Suzhou, JinagsuAges 18 years+ - NCT06556667Recruiting
Comparing two cardioversion methods for persistent AFib
This trial compares two ways of doing cardioversion (a procedure to restore normal heart rhythm) for people with persistent atrial fibrillation. It aims to see if one approach leads to a better recovery and fewer complications.
Ottawa, OntarioAges 18 years+ - NCT06589700Recruiting
Atrial Fibrillation and Stroke Risk Study
This study looks at the link between the type of atrial fibrillation (an irregular heartbeat that comes and goes) and the risk of having another stroke. It involves people who have had a recent ischemic stroke and have a certain type of AF.
London, OntarioAges 18 years+ - NCT06650995Recruiting
Ablation and Exercise for Heart Failure with Normal Pumping
This study tests whether a combination of catheter ablation (a procedure to correct irregular heartbeats) and a structured exercise program can improve symptoms and quality of life in people with diastolic heart failure and a recent onset of persistent atrial fibrillation.
MunichAges 18–99 - NCT06657404Recruiting
Modified 'Pills-in-the-Pocket' strategy for AF after ablation
This study tests a modified 'pills-in-the-pocket' approach—taking antiarrhythmic drugs only when symptoms occur—for people with non-valvular atrial fibrillation (AF) who still have arrhythmias lasting over 24 hours after their first catheter ablation. It aims to see if this strategy can safely control symptoms without needing daily medication.
Guangzhou, GuangdongAges 18 years+ - NCT07428564Recruiting
VARIPULSE catheter and TRUPULSE generator for persistent atrial fibrillation
This study tests a new catheter and generator system to treat persistent atrial fibrillation (an irregular heartbeat that lasts more than a week). It may help people whose symptoms haven't been controlled by medication and who need a procedure called ablation to fix the heart's electrical signals.
AalstAges 18–75 - NCT06730828RecruitingPhase 1/Phase 2
Amiodarone patch to prevent new irregular heartbeat after heart surgery
This trial tests a patch that releases amiodarone, a medicine that helps prevent a common irregular heartbeat after open-heart surgery. The patch is placed on the heart during surgery to stop new atrial fibrillation from starting.
Louisville, KentuckyAges 20–85 - NCT06844227Recruiting
Virtual Visit to Manage Blood Thinners Around Surgery
This study looks at whether a virtual visit can safely manage your blood thinners around the time of a planned surgery. You would stop your medication before the procedure and restart it after, but all instructions and check-ins happen remotely (phone or video).
Evanston, IllinoisAges 18–100 - NCT06935591Recruiting
AI-guided ablation for hard-to-treat atrial fibrillation
This trial uses an artificial intelligence system (vMap) to find and target abnormal electrical signals outside the pulmonary veins that may be driving atrial fibrillation (AF). The goal is to improve ablation results for people with persistent or recurrent AF.
Jonesboro, ArkansasAges 22 years+ - NCT06957366Recruiting
Managing Blood Thinners Before High-Risk Surgery
This study looks at how to safely manage your blood thinner (DOAC) around the time of a planned, high-bleed-risk surgery or procedure involving a spinal needle. The goal is to find the best way to stop and restart your medication to prevent bleeding and clotting problems.
Hartford, ConnecticutAges 18 years+ - NCT06989580Recruiting
Heart failure monitoring with a wireless implant
This trial is testing a special monitor (BIOMONITOR) that tracks your heart function and sends data wirelessly to your doctor. It aims to help manage heart failure by catching early signs of trouble so you can get treatment sooner.
GenkAges 18 years+ - NCT07024927Recruiting
Heart rhythm disorder registry
This study observes people with atrial fibrillation or ventricular tachycardia who are having their first catheter ablation procedure. The goal is to collect information to improve future treatments.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07087587Recruiting
Sleep apnea treatment for AFib: a personalized trial
This study tests whether treating sleep apnea with a CPAP machine can reduce the number of AFib episodes you have. It's a personalized 'N-of-1' trial, meaning you'll try both CPAP and no CPAP at different times to see what works best for you.
Cleveland, OhioAges 18–85 - NCT07118046Recruiting
X-ray vs. 3D mapping for balloon AFib ablation
This study compares two ways to guide a balloon-based ablation procedure for atrial fibrillation: using only X-ray (fluoroscopy) versus using a 3D mapping system. The goal is to see if one method is safer or more effective.
Madrid, MadridAges 18 years+
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Common questions
- Are there clinical trials for atrial fibrillation, paroxysmal or persistent?
- Yes. Clin2 currently lists 469 recruiting atrial fibrillation, paroxysmal or persistent studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a atrial fibrillation, paroxysmal or persistent trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a atrial fibrillation, paroxysmal or persistent trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.