Clinical trials
Atrial fibrillation clinical trials
An irregular, often rapid heart rhythm that can raise the risk of stroke. We’re tracking 546 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05638841Recruiting
Study of repeat atrial fibrillation risk after ablation
This study follows adults who have had a procedure to treat an irregular heartbeat, to understand who is more likely to have it return. It may help doctors predict risk and plan follow-up after the procedure.
BeijingAges 18 years+ - NCT05776797Recruiting
Ablation vs best medicines for CRT patients with permanent atrial fibrillation
This trial compares two approaches—an AV junction ablation procedure versus continued best medical treatment—in people who already have a heart device for heart failure (CRT) but still have ongoing permanent atrial fibrillation. It aims to improve how well your heart rhythm is controlled and how effectively the device can pace your heart.
Liberec, Liberec RegionAges 18–85 - NCT05790707Recruiting
Ablation for persistent atrial fibrillation to help memory
This study checks whether a procedure called atrial fibrillation ablation can slow memory problems in people who already have mild cognitive impairment. Participants will be tested on thinking and memory before and after treatment to see if the procedure helps.
AngersAges 60–80 - NCT05794386Recruiting
Ablation plan guided by left-heart scar map for persistent atrial fibrillation
This study tests whether using a 3D heart “scar map” helps doctors choose a better catheter ablation strategy for people with persistent atrial fibrillation (AF). It may help reduce ongoing AF by targeting the scar area in the left atrium.
Seoul, Jongno-guAges 19 years+ - NCT05836987RecruitingPhase 3
Smartwatch monitoring trial to guide blood thinner use for AF
This study tests whether continuous heart-rhythm monitoring with a smartwatch can better guide treatment for atrial fibrillation (AF) while you stay on a blood thinner. The goal is to improve safety and reduce stroke risk by catching AF patterns more closely.
Phoenix, ArizonaAges 22–85 - NCT05844501RecruitingPhase 4
Ondansetron before heart ablation for atrial fibrillation
This trial tests whether ondansetron can help people with atrial fibrillation (an abnormal heart rhythm) around the time of elective catheter ablation. It may improve the safety or effectiveness of the procedure by targeting a pathway involved in heart rhythm events.
Indianapolis, IndianaAges 18–100 - NCT05860894Recruiting
Study of new ICU atrial fibrillation
This trial looks at people who develop a new irregular heart rhythm called atrial fibrillation while in the intensive care unit (ICU). It tests an approach to help with that condition after critical illness, aiming to improve outcomes for those affected.
BesançonAges 18 years+ - NCT05872776Recruiting
Home ECG monitoring to reduce atrial fibrillation episodes
This trial uses a home heart monitor (a chest patch with an ECG) to study how atrial fibrillation (an irregular heartbeat) changes over time and how this may help manage symptoms. You may be included if you have a documented, short-lasting type of atrial fibrillation and a moderate amount of AF seen on a 14-day heart recording.
Tel AvivAges 18–85 - NCT05890664RecruitingPhase 3
Colchicine after shock treatment to stop atrial fibrillation
This trial tests whether colchicine given after cardioversion (a procedure that restores normal rhythm) helps keep the heart in normal rhythm afterward. It may help some people have fewer early returns of atrial fibrillation.
Bruderholz, Basel-LandschaftAges 18 years+ - NCT05900414Recruiting
Help choosing blood thinners to prevent stroke in AF
This trial tests a web-based decision aid that helps people with atrial fibrillation (AF) decide about stroke-prevention treatment, such as blood thinners. It may help you feel more confident and make safer choices by showing options at the right time after diagnosis.
Calgary, AlbertaAges 18 years+ - NCT05903170Recruiting
Shock energy study for heart rhythm conversion in atrial fibrillation
This trial tests whether using a specific “shock energy” during electrical cardioversion works safely and effectively for people with persistent atrial fibrillation. You might be eligible if your cardioversion is planned (not an emergency) and your doctors determine you can safely take blood thinners.
Wellington, Wellington RegionAges 18 years+ - NCT05908955Recruiting
Atrial fibrillation ablation with extra vein targeting
This trial studies a modified ablation procedure that targets the superior vena cava in addition to the pulmonary veins to help stop episodes of paroxysmal (coming and going) atrial fibrillation. It may help people whose symptoms continue despite antiarrhythmic medicines.
Beijing, Beijing MunicipalityAges 40–75 - NCT05961865Recruiting
Study of inflammation during catheter ablation for atrial fibrillation
This study measures changes in inflammation in people with atrial fibrillation (AF) who are getting a catheter ablation procedure. It may help doctors better understand what happens in the body during the procedure and why some patients do better than others.
MilanAges 18–85 - NCT05978388Recruiting
CT scan before catheter ablation for atrial fibrillation
This trial is testing whether a coronary CT angiography scan, performed before catheter ablation for atrial fibrillation, helps doctors find hidden blockages in heart arteries. It may help people without known heart disease avoid unnecessary procedures.
Hellerup, Capital RegionAges 18 years+ - NCT06023888Recruiting
Heart rhythm analysis for persistent atrial fibrillation
This study tests a new way to analyze heart signals in people with long-standing atrial fibrillation that hasn't gotten better with medication. It may help doctors understand your heart rhythm better and guide future treatments.
TaipeiAges 20–80 - NCT06108414RecruitingPhase 4
Low-dose vs standard-dose blood thinner for older adults with atrial fibrillation
This trial tests whether a lower dose of the blood thinner rivaroxaban works as well as the standard dose for people 70 and older with atrial fibrillation (an irregular heartbeat). The goal is to find the safest dose to prevent strokes while reducing bleeding risks.
Beijing, Beijing MunicipalityAges 70 years+ - NCT06145906Recruiting
Optimizing catheter ablation for atrial fibrillation
This trial is studying a way to improve the entire process of catheter ablation for atrial fibrillation. It may help people who are having this procedure for the first time and have a normal-sized left atrium and good heart function.
Zhengzhou, HenanAges 18–80 - NCT06165510Recruiting
Convergent ablation and left atrial appendage isolation for persistent AF
This trial tests a two-step procedure for persistent atrial fibrillation that combines a heart ablation with isolation of a small heart pouch. It aims to see if this approach is more effective than standard care.
LondonAges 18–80 - NCT06187311RecruitingPhase 4
Rivaroxaban for atrial fibrillation patients
This trial tests two doses of rivaroxaban (15mg and 20mg) to see how well they prevent strokes in people with non-valvular atrial fibrillation, a type of irregular heartbeat not caused by a heart valve problem. It may be an option if you need blood thinners to lower your stroke risk.
SeoulAges 19–99 - NCT06245187Recruiting
Atrial Fibrillation In-Hospital Registry
This registry study collects information on people hospitalized for atrial fibrillation or atrial flutter (types of irregular heartbeats) to help doctors learn how to improve care. By joining, you help researchers understand what treatments work best.
Dallas, TexasAges 18–125 - NCT06249269Recruiting
Lifestyle Change to Improve AF Ablation Results
This trial tests whether a healthy lifestyle program (including exercise and weight loss) can help people with atrial fibrillation (AF) who are overweight or have related health risks. You will have a catheter ablation procedure, and the study will see if lifestyle changes improve your heart's rhythm long-term.
Calgary, AlbertaAges 18 years+ - NCT06249347Recruiting
New ablation approach for persistent atrial fibrillation with stroke risk
This trial tests a new type of catheter ablation (using heat to create scar lines in the heart) for people with persistent atrial fibrillation who have a higher risk of stroke or bleeding. It aims to see if this approach can help prevent strokes and reduce the need for long-term blood thinners.
Wenzhou, ZhejiangAges 18 years+ - NCT06263608Recruiting
Sleep apnea testing and treatment for atrial fibrillation patients
This study tests a new way to check and treat sleep apnea in people with atrial fibrillation (AF). If you have AF and symptoms, you may be able to join and get sleep tracking and treatment that could help both your heart and sleep.
EdegemAges 18 years+ - NCT06275503Recruiting
Stroke Prevention Through Improved AFib Screening
This study tests a new way to find hidden atrial fibrillation (an irregular heartbeat) in people aged 75-76 in the Värmland region. If caught early, treatment can help prevent strokes.
StockholmAges 75–76
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Common questions
- Are there clinical trials for atrial fibrillation?
- Yes. Clin2 currently lists 546 recruiting atrial fibrillation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a atrial fibrillation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a atrial fibrillation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.