Clinical trials
Atrial fibrillation clinical trials
An irregular, often rapid heart rhythm that can raise the risk of stroke. We’re tracking 546 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06124612Recruiting
Blood sample study for people in the OCEANIC-AF trial
This study collects blood samples from people already taking part in the OCEANIC-AF trial. It aims to learn more about the effects of the treatment being tested.
LiverpoolAges 18 years+ - NCT06152406Recruiting
Ablate and Pace HIS for atrial fibrillation and heart failure
This study tests a new approach called 'Ablate and Pace HIS' for people with atrial fibrillation and heart failure who haven't improved with other treatments. It combines a heart ablation procedure with a special type of pacing to help your heart pump more efficiently and reduce symptoms.
Leicester, LeicestershireAges 18–100 - NCT06164808Recruiting
Comparing a wearable heart monitor to a standard Holter monitor
This study compares a new wearable heart monitor (HeartWatch) that you wear on your left bicep to the standard Holter monitor. It aims to see if the HeartWatch is as good at recording your heart's rhythm over 24-48 hours, so you might have a more comfortable option for heart monitoring.
Calgary, AlbertaAges 22 years+ - NCT06168370Recruiting
Personalized blood thinners after TAVI vs. standard care
This trial tests whether a personalized plan for blood thinners after TAVI can reduce the risk of stroke or bleeding better than the current standard of one daily blood thinner. If you've had a successful TAVI and don't need specific other blood thinners, you might be able to join.
NieuwegeinAges 18–110 - NCT06176131Recruiting
Telemedicine support for heart failure after hospital
This study tests a care program that uses telemedicine to help people with serious heart failure stay stable after leaving the hospital. It focuses on those who needed multiple hospital stays recently.
FrederiksbergAges Any age - NCT06187155Recruiting
How education level affects warfarin self-management
This study looks at how a person's education level affects their ability to manage their own blood-thinning medication (like warfarin). It aims to see if more education leads to better health outcomes.
AswānAges 18 years+ - NCT06216769Recruiting
Pill-in-the-pocket blood thinners after AF ablation
This study tests a 'pill-in-the-pocket' approach for blood thinners after a catheter ablation for atrial fibrillation. Instead of taking a daily blood thinner, you may only take it when needed, which could reduce the risk of bleeding while still preventing strokes.
SeoulAges 19–89 - NCT06220006Recruiting
Comparing heart tissue burns for atrial fibrillation treatment
This study compares two ways to create small burns in the heart tissue to fix an irregular heartbeat (atrial fibrillation). It uses a special MRI to see how well each method works.
Barcelona, CataloniaAges 18 years+ - NCT06253000Recruiting
Heat vs. Freezing for the Back of the Heart
This trial tests two ways to treat the back wall of the heart's left chamber in people with stubborn atrial fibrillation. It compares radiofrequency (heat) and cryoablation (freezing) to see which is safer and works better.
MoscowAges 18–80 - NCT06383975Recruiting
Two new treatments for AF that returned after first procedure
This trial tests two new treatments for persistent atrial fibrillation that came back after an initial procedure. One uses a targeted chemical injection, the other uses a special energy field to re-isolate the veins involved.
BrugesAges 18 years+ - NCT06392932Recruiting
Esophageal temperature monitoring during heart ablation
This study tests a new way to monitor the temperature in your esophagus during a standard heart ablation procedure for atrial fibrillation. The goal is to see if the new catheter (Q-DOT Micro) safely heats the heart tissue without harming the esophagus.
Los Angeles, CaliforniaAges 18 years+ - NCT06445439Recruiting
Finding the Best Pacemaker Rate for Heart Failure
This study tests whether adjusting the pacing rate on a special pacemaker (CRT or conduction system pacing) can improve heart function and daily symptoms in people with atrial fibrillation and heart failure.
Washington D.C., District of ColumbiaAges 18–90 - NCT06455644Recruiting
CT vs. X-ray for sizing heart device in AF treatment
This study tests whether using a CT scan or a special X-ray (DSA) is better for picking the right size of a left atrial appendage closure device during a combined ablation and closure procedure. It aims to make the procedure safer and more effective.
Foshan, GuangdongAges 18 years+ - NCT06465459Recruiting
Testing the LAMBRE device for left atrial appendage closure
This study is testing a device called LAMBRE that is used to close a small pocket in the heart (the left atrial appendage). The goal is to see how well it works in everyday medical practice for people who need this closure procedure.
PessacAges 18 years+ - NCT06527105Recruiting
Sleep quality and recovery after heart surgery
This study looks at how your sleep affects recovery after planned heart surgery. Researchers want to see if better sleep leads to better outcomes, so they will track your sleep quality and health after the operation.
Kochi, KeralaAges 18–80 - NCT06542263Recruiting
CPAP for preventing AF recurrence after ablation in people with AF and sleep apnea
This study tests whether using a CPAP machine at night can help prevent atrial fibrillation from coming back after a heart procedure called catheter ablation. It is for people who have both AF and moderate to severe obstructive sleep apnea.
Suzhou, JinagsuAges 18 years+ - NCT06552845Recruiting
Heart scan to guide atrial fibrillation treatment
This trial uses a special MRI scan to see if heart scarring matches low-voltage areas detected during catheter ablation for atrial fibrillation. If the scan results are consistent, it could help doctors better plan ablation procedures.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06556667Recruiting
Comparing two cardioversion methods for persistent AFib
This trial compares two ways of doing cardioversion (a procedure to restore normal heart rhythm) for people with persistent atrial fibrillation. It aims to see if one approach leads to a better recovery and fewer complications.
Ottawa, OntarioAges 18 years+ - NCT06575881Recruiting
Genetic heart muscle disease and heart rhythm study
This study looks at the risk of a fast heart rhythm (ventricular tachycardia) in people with genetic heart muscle diseases. It tests whether having a specific genetic change affects the success of a heart ablation procedure.
Nashville, TennesseeAges 18 years+ - NCT06578793Recruiting
Catheter plus vein ablation for atrial fibrillation with heart failure
This trial tests whether adding a vein ablation to standard catheter ablation helps people with persistent atrial fibrillation and heart failure. It aims to find the best treatment to improve heart function and reduce symptoms.
Changsha, HunanAges 18–80 - NCT06589700Recruiting
Atrial Fibrillation and Stroke Risk Study
This study looks at the link between the type of atrial fibrillation (an irregular heartbeat that comes and goes) and the risk of having another stroke. It involves people who have had a recent ischemic stroke and have a certain type of AF.
London, OntarioAges 18 years+ - NCT06646601Recruiting
Garden-based program for heart and stroke recovery
This trial tests a preventive program that uses a therapeutic garden to help people with heart or blood vessel conditions. It looks at whether patients find the program helpful and easy to take part in.
GapAges 18 years+ - NCT06650995Recruiting
Ablation and Exercise for Heart Failure with Normal Pumping
This study tests whether a combination of catheter ablation (a procedure to correct irregular heartbeats) and a structured exercise program can improve symptoms and quality of life in people with diastolic heart failure and a recent onset of persistent atrial fibrillation.
MunichAges 18–99 - NCT06657404Recruiting
Modified 'Pills-in-the-Pocket' strategy for AF after ablation
This study tests a modified 'pills-in-the-pocket' approach—taking antiarrhythmic drugs only when symptoms occur—for people with non-valvular atrial fibrillation (AF) who still have arrhythmias lasting over 24 hours after their first catheter ablation. It aims to see if this strategy can safely control symptoms without needing daily medication.
Guangzhou, GuangdongAges 18 years+
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Common questions
- Are there clinical trials for atrial fibrillation?
- Yes. Clin2 currently lists 546 recruiting atrial fibrillation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a atrial fibrillation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a atrial fibrillation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.