Clinical trials
Atrial fibrillation clinical trials
An irregular, often rapid heart rhythm that can raise the risk of stroke. We’re tracking 546 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07428564Recruiting
VARIPULSE catheter and TRUPULSE generator for persistent atrial fibrillation
This study tests a new catheter and generator system to treat persistent atrial fibrillation (an irregular heartbeat that lasts more than a week). It may help people whose symptoms haven't been controlled by medication and who need a procedure called ablation to fix the heart's electrical signals.
AalstAges 18–75 - NCT06730828RecruitingPhase 1/Phase 2
Amiodarone patch to prevent new irregular heartbeat after heart surgery
This trial tests a patch that releases amiodarone, a medicine that helps prevent a common irregular heartbeat after open-heart surgery. The patch is placed on the heart during surgery to stop new atrial fibrillation from starting.
Louisville, KentuckyAges 20–85 - NCT06731673Recruiting
HSP47 protein study in blood clots
This study looks at a protein called HSP47 in people with blood clots, heart attacks, or strokes caused by atrial fibrillation, compared to healthy volunteers. It aims to learn more about how blood clots form and may lead to better treatments.
Aarhus, Central RegionAges 18 years+ - NCT06747091Recruiting
Ablation study for people with persistent atrial fibrillation
This trial tests a catheter ablation procedure for people with persistent atrial fibrillation (a type of irregular heartbeat that lasts more than 7 days but less than a year). It aims to see if the procedure is safe and effective for restoring a normal heart rhythm.
Manhasset, New YorkAges 18–80 - NCT06823466Recruiting
Stroke study for patients on blood thinners
This study looks at people who had a stroke while taking blood thinners (anticoagulants) for an irregular heartbeat. It aims to learn more about these strokes and how to better prevent them in the future.
ZagrebAges 18 years+ - NCT06844227Recruiting
Virtual Visit to Manage Blood Thinners Around Surgery
This study looks at whether a virtual visit can safely manage your blood thinners around the time of a planned surgery. You would stop your medication before the procedure and restart it after, but all instructions and check-ins happen remotely (phone or video).
Evanston, IllinoisAges 18–100 - NCT06861673Recruiting
Combined PVI and LAAC study
This study is testing if a procedure that combines two treatments—pulmonary vein isolation for atrial fibrillation and left atrial appendage closure to lower stroke risk—can be done safely together. It's for people who need both treatments.
Hamburg, Free and Hanseatic City of HamburgAges Any age - NCT06878066RecruitingPhase 3
Clot-busting treatment after stroke while on Factor Xa inhibitor
This trial tests a clot-busting drug (thrombolysis) for people who had a stroke while on a Factor Xa inhibitor blood thinner. It aims to see if the drug can still safely break up the clot and reduce disability.
Bærum, GjettumAges 18 years+ - NCT06903845Recruiting
Apixaban study for atrial fibrillation
This trial tests whether apixaban, a blood thinner, works well for people with atrial fibrillation who also have heart or circulation conditions. It uses a smartphone app to help track your treatment.
Seongnam, GyeonggidoAges 19 years+ - NCT06906432Recruiting
Brain-Heart Injury After Brain Bleed Study
This study looks at how a brain bleed can affect the heart. Researchers hope to understand the link between brain and heart injury to help improve care for people who have had a brain bleed.
Beijing, Beijing MunicipalityAges 18–80 - NCT06935513Recruiting
Wearable devices for stroke prevention
This trial tests if using a smart wearable device can help people at high risk for stroke stay active and reduce their risk. You may be able to join if you have certain health conditions or habits that increase your stroke risk.
Nantong, JiangsuAges 30 years+ - NCT06935591Recruiting
AI-guided ablation for hard-to-treat atrial fibrillation
This trial uses an artificial intelligence system (vMap) to find and target abnormal electrical signals outside the pulmonary veins that may be driving atrial fibrillation (AF). The goal is to improve ablation results for people with persistent or recurrent AF.
Jonesboro, ArkansasAges 22 years+ - NCT06953726RecruitingPhase 4
Comparing apixaban and rivaroxaban for atrial fibrillation
This study compares two common blood thinners, apixaban and rivaroxaban, in veterans with atrial fibrillation or flutter to see which one is safer and works better. If you are already taking one of these medicines, you may be able to join.
Miami, FloridaAges 65 years+ - NCT06957366Recruiting
Managing Blood Thinners Before High-Risk Surgery
This study looks at how to safely manage your blood thinner (DOAC) around the time of a planned, high-bleed-risk surgery or procedure involving a spinal needle. The goal is to find the best way to stop and restart your medication to prevent bleeding and clotting problems.
Hartford, ConnecticutAges 18 years+ - NCT06989580Recruiting
Heart failure monitoring with a wireless implant
This trial is testing a special monitor (BIOMONITOR) that tracks your heart function and sends data wirelessly to your doctor. It aims to help manage heart failure by catching early signs of trouble so you can get treatment sooner.
GenkAges 18 years+ - NCT07024927Recruiting
Heart rhythm disorder registry
This study observes people with atrial fibrillation or ventricular tachycardia who are having their first catheter ablation procedure. The goal is to collect information to improve future treatments.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07076329Recruiting
Using a special diet to prevent malnutrition in older heart patients
This trial tests whether a special type of food can help prevent malnutrition in older adults with heart failure or atrial fibrillation. It looks at how the bacteria in your gut and inflammation in your body affect your brain and overall health.
FlorenceAges 70 years+ - NCT07087587Recruiting
Sleep apnea treatment for AFib: a personalized trial
This study tests whether treating sleep apnea with a CPAP machine can reduce the number of AFib episodes you have. It's a personalized 'N-of-1' trial, meaning you'll try both CPAP and no CPAP at different times to see what works best for you.
Cleveland, OhioAges 18–85 - NCT07118046Recruiting
X-ray vs. 3D mapping for balloon AFib ablation
This study compares two ways to guide a balloon-based ablation procedure for atrial fibrillation: using only X-ray (fluoroscopy) versus using a 3D mapping system. The goal is to see if one method is safer or more effective.
Madrid, MadridAges 18 years+ - NCT07119528Recruiting
App-based care after heart ablation
This study tests whether a smartphone app can help people recover after a new type of heart ablation called pulse field ablation for atrial fibrillation. It aims to see if the app improves follow-up care and quality of life.
SeoulAges 19 years+ - NCT07122947Recruiting
Apple Watch to detect AFib after heart surgery
This study tests if an Apple Watch can help detect when atrial fibrillation (an irregular heartbeat) comes back after heart surgery. You'll wear an Apple Watch and a small skin patch (Zio Patch) to track your heart rhythm.
St Louis, MissouriAges 22 years+ - NCT07129564Recruiting
Stepwise treatment for persistent atrial fibrillation
This study tests a stepwise treatment plan for people with persistent atrial fibrillation (a long-lasting irregular heartbeat) who also have an enlarged left atrium. It aims to see if a medication called amiodarone plus a cardioversion procedure can help restore normal rhythm.
ChongqingAges 18–70 - NCT07149688Recruiting
Heart disease health program for older adults in Qujiang
This study follows older adults in Qujiang District who have chronic heart or blood vessel conditions. It aims to improve care through village-based management and help researchers better understand how to support long-term heart health.
Beijing, Beijing MunicipalityAges 60 years+ - NCT07173855RecruitingPhase 4
Magnesium replacement in ICU patients
This trial tests whether giving magnesium as part of a standard hospital protocol can lower the risk of irregular heartbeat and improve survival in patients admitted to the intensive care unit.
Ajax, OntarioAges 16 years+
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Common questions
- Are there clinical trials for atrial fibrillation?
- Yes. Clin2 currently lists 546 recruiting atrial fibrillation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a atrial fibrillation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a atrial fibrillation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.