Clinical trials
Atrial fibrillation clinical trials
An irregular, often rapid heart rhythm that can raise the risk of stroke. We’re tracking 543 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05717725RecruitingPhase 3
Pulsed heart ablation vs fake procedure for irregular heartbeat
This trial tests whether pulsed-field ablation (a targeted treatment meant to stop abnormal heart signals) works better than a sham, or “placebo,” ablation. It is for certain people with atrial fibrillation (AF) to see if symptoms and heart rhythm outcomes improve.
PragueAges 18 years+ - NCT07462910Recruiting
Checking diaphragm nerve function after pulsed field ablation
This study looks at how a new type of catheter ablation (pulsed field ablation) for atrial fibrillation affects the phrenic nerve, which controls the diaphragm. Researchers will use X-rays to see if the treatment causes any temporary diaphragm problems.
MontrealAges 18 years+ - NCT07439016Recruiting
LA function after pulse field ablation for paroxysmal AF
This trial tests how pulse field ablation (a treatment that uses short electrical pulses to correct irregular heartbeats) affects the left atrium's function in people with paroxysmal atrial fibrillation (AFib that comes and goes). It may help if you have paroxysmal AFib and are in normal rhythm at the start of the procedure.
PragueAges 18 years+ - NCT07429214Recruiting
Study of a new catheter for atrial fibrillation ablation
This trial tests a new catheter system to treat atrial fibrillation (AF) by creating small scars in the heart to block faulty signals. It may help people with symptoms that continue despite medication and who are scheduled for a standard ablation procedure.
AalstAges 18–75 - NCT07428564Recruiting
VARIPULSE catheter and TRUPULSE generator for persistent atrial fibrillation
This study tests a new catheter and generator system to treat persistent atrial fibrillation (an irregular heartbeat that lasts more than a week). It may help people whose symptoms haven't been controlled by medication and who need a procedure called ablation to fix the heart's electrical signals.
AalstAges 18–75 - NCT07421076Recruiting
Grid mapping study for atrial fibrillation ablation
This trial tests a new mapping tool to help doctors find and treat the source of atrial fibrillation (AF) during a standard ablation procedure. It may offer a more precise way to guide treatment for people with AF that comes and goes.
Jinan, ShandongAges 18 years+ - NCT07414121Recruiting
Vascular closure vs manual compression after AF ablation
This study compares two methods to close the blood vessel after a catheter ablation for atrial fibrillation (AF). It may help reduce bleeding or other problems at the access site.
HamburgAges 18–95 - NCT07405359Recruiting
Comparing ablation methods for persistent atrial fibrillation
This trial tests a newer, possibly safer way to treat persistent atrial fibrillation using pulsed field ablation. It compares standard vein isolation alone to adding extra ablation spots to improve success.
San Francisco, CaliforniaAges 18 years+ - NCT07389434Recruiting
Testing reused catheters for atrial fibrillation treatment
This trial tests whether reusing special catheters to treat atrial fibrillation is safe, effective, and better for costs and the environment. It may help people with atrial fibrillation who need a procedure called pulmonary vein isolation.
ZagrebAges 18 years+ - NCT07390214Recruiting
Comparing two catheters for repeat atrial fibrillation ablation
This study compares two types of catheters (AFFERA vs. standard contact-force guided) for a repeat ablation procedure in people whose atrial fibrillation or related symptoms returned after a first ablation. It aims to find which catheter works best for a second treatment.
Frankfurt am Main, HesseAges 18–85 - NCT07385417Recruiting
Early AF treatment for heart failure with preserved pumping function
This study tests using a new electrical pulse treatment for atrial fibrillation (AF) early on, in people who also have a type of heart failure where the heart pumps normally but is stiff. The goal is to see if this treatment helps manage both conditions better.
Frankfurt am MainAges 18–80 - NCT06823466Recruiting
Stroke study for patients on blood thinners
This study looks at people who had a stroke while taking blood thinners (anticoagulants) for an irregular heartbeat. It aims to learn more about these strokes and how to better prevent them in the future.
ZagrebAges 18 years+ - NCT07372716Recruiting
Blood thinner safety during cancer surgery
This trial studies the safety of managing blood thinners (like apixaban or warfarin) around the time of cancer surgery or procedures. It aims to help doctors understand how to best handle these medications to reduce risks.
OttawaAges 18 years+ - NCT07347691Recruiting
AI predicts atrial fibrillation after stroke of unknown cause
This trial uses an artificial intelligence (AI) program to see if it can predict which patients who had a stroke from an unknown cause might develop atrial fibrillation (an irregular heart rhythm). If you have a small heart monitor already implanted, the AI will analyze your ECGs to find early signs of AFib, which could help prevent future strokes.
AnsanAges 30 years+ - NCT07339007Enrolling by invitation
Validating a heart ultrasound training program for family doctors
This study tests whether a training program helps family doctors use a focused heart ultrasound (FoCUS) to assess patients. If you need a heart ultrasound as part of your regular care, you may be able to join.
Barcelona, CataloniaAges 15 years+ - NCT05353140Recruiting
Left atrial appendage device vs blood thinners after stent
This trial compares a heart device that can help prevent blood clots in the heart (called LAAO) versus long-term blood thinners for people who have atrial fibrillation and recently had a stent placed. It aims to see which approach better prevents stroke and related blood-clot problems while keeping side effects manageable.
Xi'an, ShannxiAges 18 years+ - NCT03987633Recruiting
Study links health records and samples to understand health gaps
This study asks people affected by a specific illness (or their family member) to share saliva (and sometimes blood) and answer health and quality-of-life questions. The goal is to better understand and reduce health inequality by matching new information with medical records.
Wolverhampton, West MidlandsAges 6 years+ - NCT06844227Recruiting
Virtual Visit to Manage Blood Thinners Around Surgery
This study looks at whether a virtual visit can safely manage your blood thinners around the time of a planned surgery. You would stop your medication before the procedure and restart it after, but all instructions and check-ins happen remotely (phone or video).
Evanston, IllinoisAges 18–100 - NCT07295769Recruiting
Detecting hidden atrial fibrillation after stroke of unknown cause
This study uses a small patch (M.E.M.O. Patch) to continuously monitor your heart rhythm for hidden atrial fibrillation, a treatable cause of stroke. The goal is to see if the patch can find irregular heartbeats that standard tests might miss.
Seoul, Songpa-guAges 19 years+ - NCT07287345RecruitingPhase 4
Colchicine’s effect on inflammation after heart bypass surgery
This trial tests whether the drug colchicine can reduce inflammation after planned coronary artery bypass graft (CABG) surgery. It may help patients recover better by lowering inflammatory markers.
Lexington, KentuckyAges 18–99 - NCT07283666Enrolling by invitation
Heart care quality program for AFib and heart failure
This trial aims to improve care for people with atrial fibrillation (a type of irregular heartbeat) or heart failure with reduced pumping strength. It focuses on making sure you get the right treatments based on your health history and recent visits to a heart doctor.
New York, New YorkAges 18–90 - NCT03710902Recruiting
Mobile coaching to lower heart risk after stroke
This trial tests whether a mobile technology program can help people manage risk factors like high blood pressure after an ischemic stroke or a “mini-stroke” (TIA). It may help lower future cardiovascular risks by improving day-to-day control of these conditions.
HämeenlinnaAges 40 years+ - NCT07278089Recruiting
AF screening for people with heart changes on echo
This trial checks if people with certain heart conditions seen on an echo (like an enlarged heart or stiff heart muscle) have undetected atrial fibrillation (AF). It aims to find AF early so it can be treated to prevent strokes.
TaipeiAges 20 years+ - NCT07275151Recruiting
Testing a new heart procedure for atrial fibrillation
This trial tests a new method called pulsed field ablation (PFA) to treat irregular heartbeats (atrial fibrillation) by isolating the veins that carry blood to your heart. It aims to see how well this procedure works and if it's safe for you.
Ypsilanti, MichiganAges 21 years+
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Common questions
- Are there clinical trials for atrial fibrillation?
- Yes. Clin2 currently lists 543 recruiting atrial fibrillation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a atrial fibrillation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a atrial fibrillation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.