Clinical trials
Atrial fibrillation clinical trials
An irregular, often rapid heart rhythm that can raise the risk of stroke. We’re tracking 541 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07267949RecruitingPhase 2
Study of AP31969 for atrial fibrillation rhythm control
This study tests a new medication, AP31969, to control heart rhythm in people with atrial fibrillation. It compares the drug to a placebo to see if it can reduce how often AF episodes happen over time.
Plovdiv, PDAges 18 years+ - NCT05903170Recruiting
Shock energy study for heart rhythm conversion in atrial fibrillation
This trial tests whether using a specific “shock energy” during electrical cardioversion works safely and effectively for people with persistent atrial fibrillation. You might be eligible if your cardioversion is planned (not an emergency) and your doctors determine you can safely take blood thinners.
Wellington, Wellington RegionAges 18 years+ - NCT05900414Recruiting
Help choosing blood thinners to prevent stroke in AF
This trial tests a web-based decision aid that helps people with atrial fibrillation (AF) decide about stroke-prevention treatment, such as blood thinners. It may help you feel more confident and make safer choices by showing options at the right time after diagnosis.
Calgary, AlbertaAges 18 years+ - NCT07217067RecruitingPhase 2
Study of PKN605 for people with atrial fibrillation
This trial tests a new medicine called PKN605 for people with atrial fibrillation (irregular heartbeat). The goal is to see if it can safely help control heart rhythm. You will need to have had at least two AF episodes recently and meet other heart health criteria.
Tupelo, MississippiAges 18 years+ - NCT06598280Recruiting
Going home same day vs staying overnight after afib ablation
This trial compares whether it is safe to go home a few hours after a heart procedure for atrial fibrillation (afib) versus staying in the hospital overnight. It will help doctors understand which approach is better for your recovery.
Lübeck, Schleswig-HolsteinAges 18 years+ - NCT06322017Recruiting
Early vein isolation for atrial fibrillation in older adults
This study compares doing vein isolation soon after diagnosis versus usual care in people 75+ with new or early atrial fibrillation. The goal is to see if early treatment prevents the condition from getting worse and improves quality of life.
Nantes, Loire AtlantiqueAges 75 years+ - NCT07181590Recruiting
Balloon-based ablation for atrial fibrillation: post-approval study
This trial tests a balloon catheter that uses pulsed field energy to treat atrial fibrillation (AF) in people who have tried medication without success. It aims to see how well it works in real-world use.
LinzAges 18 years+ - NCT06949319Recruiting
Stroke Risk and Blood Clots in New Atrial Fibrillation
This study looks at stroke risk and blood clotting in people who have just been diagnosed with atrial fibrillation (AFib) that is not caused by a heart valve problem, and who have not yet taken blood thinners. It aims to better understand how blood clots form in this condition.
Esbjerg, Region SyddanmarkAges 18 years+ - NCT07171463Recruiting
New ablation for paroxysmal atrial fibrillation
This trial tests a new treatment that uses two types of energy (pulsed field and radiofrequency) to fix the heart's electrical signals in people with paroxysmal atrial fibrillation (AFib that comes and goes). It aims to be more effective and safer than standard ablation alone.
Rzeszów, Podkarpackie VoivodeshipAges 18 years+ - NCT07156877Recruiting
Balloon Catheter Ablation for Atrial Fibrillation
This study tests a new balloon catheter that uses pulsed electric fields to isolate the veins that carry blood from your lungs to your heart. It may be a treatment option for people with atrial fibrillation who are scheduled for an ablation procedure.
BrugesAges 18 years+ - NCT07159399Enrolling by invitation
Pharmacist-led education to help patients take blood thinners
This trial tests if talking with a pharmacist helps people with atrial fibrillation remember to take their blood thinner medicine correctly. It may improve stroke prevention.
TaipeiAges 18 years+ - NCT07141745Recruiting
Comparing energy types for repeat atrial fibrillation treatment
This trial compares two different energy methods (electroporation vs radiofrequency ablation) guided by 3D imaging for people who have had a prior ablation for atrial fibrillation but still have recurrences. It aims to find which method is safer and more effective for repeat procedures.
WroclawAges 18–85 - NCT07116525Recruiting
Study of heart mapping for abnormal rhythms
This trial tests a special catheter to map abnormal heart rhythms like ventricular tachycardia or atrial fibrillation. It may help patients who need a procedure to find and treat the source of these fast or irregular heartbeats.
BrugesAges 18 years+ - NCT07095959Recruiting
Ethanol vein infusion plus pulsed field ablation for paroxysmal AF
This study compares two treatments for paroxysmal atrial fibrillation (AF that comes and goes): using pulsed electric field ablation alone versus combining it with ethanol infusion into a specific vein. The goal is to see which approach works better for first-time ablation patients.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07100483Enrolling by invitation
Comparing surgery methods for atrial fibrillation
This trial studies different surgical techniques for treating atrial fibrillation during heart surgery. It may help people with a history of AFib who are already scheduled for open-heart surgery.
Grand Rapids, MichiganAges 18–85 - NCT02741349Recruiting
Checking stroke and bleeding risks in atrial fibrillation
This study looks at how to better predict both stroke risk and bleeding risk in people with atrial fibrillation. It may help doctors choose safer blood-thinner treatment and follow-up plans.
ParisAges 18 years+ - NCT04700826RecruitingPhase 4
Preventing stroke, death, and memory decline in atrial fibrillation
This trial looks at ways to help people with atrial fibrillation lower their risk of stroke, premature death, and worsening memory. It may help by identifying which prevention approach works best for a broader community of patients.
Birmingham, West MidlandsAges 55–73 - NCT07083115Enrolling by invitation
Using MRI to study atrial fibrillation
This trial uses advanced MRI scans to better understand atrial fibrillation (AFib). If you have been diagnosed with AFib and can safely undergo an MRI, you may be able to join this study at the Cleveland Clinic.
Cleveland, OhioAges 18 years+ - NCT05890664RecruitingPhase 3
Colchicine after shock treatment to stop atrial fibrillation
This trial tests whether colchicine given after cardioversion (a procedure that restores normal rhythm) helps keep the heart in normal rhythm afterward. It may help some people have fewer early returns of atrial fibrillation.
Bruderholz, Basel-LandschaftAges 18 years+ - NCT07036965Recruiting
Comparing two types of ablation catheters for atrial fibrillation
This trial tests two different catheters that use pulsed field energy to treat atrial fibrillation (a heart rhythm problem). It aims to find which one works better for people who need blood thinners but have a high risk of bleeding.
HangzhouAges 118 years+ - NCT06989775Recruiting
BoxX-NoAF Trial: Preventing Stroke During Heart Surgery
This trial tests a device to close a small pouch in the heart during planned bypass surgery, to help prevent future strokes. It is for people who have never had an irregular heartbeat and are at higher stroke risk due to age and other factors.
Scottsdale, ArizonaAges 65 years+ - NCT06985901Recruiting
Pulsed-field ablation for persistent atrial fibrillation
This trial tests a new type of ablation (pulsed-field) to treat persistent atrial fibrillation (AFib) that lasts more than 7 days. You may qualify if you have symptoms and haven't had other heart ablation procedures except for one specific type.
NiceAges 18 years+ - NCT06988202Enrolling by invitation
Comparing repeat ablation methods for atrial fibrillation
This trial compares different techniques for a second heart ablation procedure in people with atrial fibrillation (AFib) who have already had one ablation. It aims to find the best approach to stop AFib from coming back.
Rochester, New YorkAges 18 years+ - NCT05266144Recruiting
Catheter ablation for non-valvular atrial fibrillation
This trial studies catheter ablation, a procedure that targets heart rhythm triggers, for people with atrial fibrillation (an irregular heartbeat). It may help improve rhythm control, but you must meet specific heart and testing requirements and avoid certain conditions.
Beijing, Beijing MunicipalityAges 18–80
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Common questions
- Are there clinical trials for atrial fibrillation?
- Yes. Clin2 currently lists 541 recruiting atrial fibrillation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a atrial fibrillation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a atrial fibrillation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.