Clinical trials
Atrial fibrillation clinical trials
An irregular, often rapid heart rhythm that can raise the risk of stroke. We’re tracking 546 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06322017Recruiting
Early vein isolation for atrial fibrillation in older adults
This study compares doing vein isolation soon after diagnosis versus usual care in people 75+ with new or early atrial fibrillation. The goal is to see if early treatment prevents the condition from getting worse and improves quality of life.
Nantes, Loire AtlantiqueAges 75 years+ - NCT06324188Recruiting
Early ablation for afib to prevent stroke in high-risk patients
This trial tests whether an early procedure (catheter ablation) for atrial fibrillation (AF) can prevent strokes in people with a high risk of stroke. The goal is to see if this treatment is safer and more effective than standard care for patients with other health conditions.
Multiple LocationsAges 18 years+ - NCT06355063Recruiting
CellFX device for atrial fibrillation during open-heart surgery
This trial tests a new device called CellFX that uses nanosecond pulsed field ablation to treat atrial fibrillation during open-heart surgery. It may help you if you already need heart surgery and also have AFib.
ViennaAges 18–85 - NCT06363604Recruiting
Alcohol injection with ablation for persistent atrial fibrillation
This trial is testing a new approach to treat persistent atrial fibrillation (a type of irregular heartbeat) by combining standard catheter ablation with a special injection of alcohol (ethanol) into certain heart veins. It may help people whose symptoms haven't improved with medication.
Shanghai, Shanghai MunicipalityAges 18–85 - NCT06399666Recruiting
Inflammation markers and genes in atrial fibrillation prediction
This trial looks at whether certain blood markers and genetic information can help predict atrial fibrillation (irregular heartbeat). It studies how inflammation might play a role, and aims to find better ways to identify people at risk.
Jönköping, SmålandAges 18 years+ - NCT06402617Recruiting
Ablation of active spots in atrial fibrillation
This trial is testing a new way to treat atrial fibrillation by using a catheter to target the specific areas in the heart that trigger the irregular heartbeat. If you have persistent atrial fibrillation and haven't had prior catheter ablation, you may be eligible to join.
LondonAges 18–85 - NCT06519747Recruiting
Detecting irregular heartbeat after non-heart surgery
This trial uses a monitoring device to check for a common but often overlooked irregular heartbeat (atrial fibrillation) after non-cardiac surgery. The goal is to detect and treat it early to prevent complications like stroke.
Hamilton, OntarioAges 18–120 - NCT06557616Recruiting
CoolCryo system for treating atrial fibrillation during mitral valve surgery
This trial tests a new tool called CoolCryo that freezes heart tissue to treat atrial fibrillation while you have mitral valve surgery. If you are already having this surgery and also have AF, this device could correct both problems at once.
BydgoszczAges 18 years+ - NCT06557876Recruiting
Pulse field ablation for atrial fibrillation mechanics
This study tests if a new type of energy called pulse field ablation (a procedure that uses short bursts of electric pulses) works as well as standard ablation for restoring normal heart rhythm in patients with episodes of irregular heartbeat. It may help your heart pump more normally.
Paris, FranceAges 18 years+ - NCT06584266Recruiting
Cardiac imaging registry for atrial fibrillation
This study collects data from heart imaging tests (TEE) in people with atrial fibrillation or atrial flutter. It aims to better understand how these imaging results relate to treatment decisions and outcomes.
BrnoAges 18 years+ - NCT06598280Recruiting
Going home same day vs staying overnight after afib ablation
This trial compares whether it is safe to go home a few hours after a heart procedure for atrial fibrillation (afib) versus staying in the hospital overnight. It will help doctors understand which approach is better for your recovery.
Lübeck, Schleswig-HolsteinAges 18 years+ - NCT06615596RecruitingEarly Phase 1
Stopping blood thinners after successful atrial fibrillation ablation
This trial tests whether it is safe to stop taking blood thinners (anticoagulants) after a successful ablation procedure for atrial fibrillation. If you have had no AF for 3 months after your first ablation, you may be able to stop these medications, reducing your risk of bleeding.
Boston, MassachusettsAges 18 years+ - NCT06630936Recruiting
Studying atrial fibrillation with mitral regurgitation
This trial tests a treatment for people with atrial fibrillation who also have a leaky mitral valve. It aims to see if treating both conditions together can improve symptoms.
Hangzhou, ZhejiangAges 18–80 - NCT06647485Recruiting
Pulsed Field Ablation for Paroxysmal Atrial Fibrillation
This trial studies a new procedure called pulsed field ablation to treat brief episodes of atrial fibrillation (AFib). The goal is to see if it can help reset the heart's natural electrical system and reduce symptoms.
Aalst, BelgiumAges 18–70 - NCT06654401Recruiting
Using electrical shock to restore normal heart rhythm after surgery
This study looks at whether giving an electrical shock (cardioversion) right after heart surgery can help people with long-lasting atrial fibrillation keep a normal heartbeat. It may help guide future treatment decisions for patients who have not gotten better with medication.
Saint Petersburg, Sankt-PeterburgAges 18 years+ - NCT06675383Recruiting
Screening for atrial fibrillation after stroke
This trial tests whether extended monitoring can detect hidden atrial fibrillation (an irregular heartbeat) in people who have had a stroke. If found, treatment can help prevent another stroke.
Sogneprest Munthe-kaas Vei 100, GjettumAges 18 years+ - NCT06696170Recruiting
New catheter for atrial fibrillation using nanosecond pulses
This trial tests a new catheter that uses very short electrical pulses to treat atrial fibrillation (a type of irregular heartbeat). It may help people whose AF symptoms continue despite medication.
HasseltAges 18–75 - NCT06698159Recruiting
Wider pulmonary vein isolation in AFib ablation with single-shot cryoablation
This study tests a new approach to a common procedure for atrial fibrillation (AFib) called pulmonary vein isolation. It uses a single-shot cryoablation technique to treat people with paroxysmal or persistent AFib.
Pozzilli, IserniaAges 18 years+ - NCT06699342Recruiting
Pacing and heart ablation for atrial fibrillation
This trial tests a combination of heart pacing and a specialized ablation procedure in older adults with permanent atrial fibrillation that hasn't improved with other treatments. It aims to improve symptoms and reduce hospital stays related to heart failure.
Seoul, Jongno-guAges 65 years+ - NCT07684053Recruiting
Digital screening for irregular heartbeat to prevent stroke
This study tests if using a digital device (like a smartwatch or phone) can help find an irregular heartbeat called atrial fibrillation. Finding it early may help prevent stroke, especially in people over 65.
Innsbruck, TyrolAges 65 years+ - NCT06754176Recruiting
Alcohol and AFib: Avoiding vs. Allowing Drinking
This study tests whether avoiding alcohol completely for two weeks helps people with AFib have fewer episodes, compared to allowing regulated drinking. You will be randomly assigned to one of the two groups.
San Francisco, CaliforniaAges 21 years+ - NCT06775028Recruiting
Integrated care for older adults with atrial fibrillation
This trial is testing a new approach to care for older adults with atrial fibrillation (an irregular heartbeat) who also have other health conditions. It aims to see if a more integrated, team-based care plan helps improve their overall health and quality of life.
HaskovoAges 65 years+ - NCT06784466Recruiting
New ablation procedure for atrial fibrillation
This study is testing a new type of ablation procedure for atrial fibrillation (an irregular heart rhythm). It uses special energy to create scar tissue in the heart to block faulty electrical signals. If you have AF that isn’t controlled by medication, you may qualify.
Birmingham, AlabamaAges 18–80 - NCT06802081RecruitingPhase 2
Tirzepatide for weight loss in people with atrial fibrillation
This study tests whether tirzepatide, a medication that helps with weight loss and blood sugar control, can improve the heart rhythm condition atrial fibrillation. If you have AFib and are overweight or obese, this trial may be an option for you.
Cleveland, OhioAges 18–80
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Common questions
- Are there clinical trials for atrial fibrillation?
- Yes. Clin2 currently lists 546 recruiting atrial fibrillation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a atrial fibrillation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a atrial fibrillation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.