Clinical trials
Diabetic Foot Disease clinical trials
Below are recruiting diabetic foot disease clinical trials, each written for real people, not researchers. We’re tracking 87 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06154915Recruiting
Immune cells in diabetic foot ulcers
This study looks at immune cells in chronic foot ulcers caused by diabetes. It may help researchers understand how these ulcers heal, which could lead to better treatments.
Huddinge, Stockholm CountyAges 18–98 - NCT05415878Recruiting
Comparing removable boot designs for diabetic foot ulcers
This study compares different removable cast walkers (special boots) to see which is easier for people with diabetic foot ulcers to use. If you join, you'll try one of these boots and share your experience, which may help heal your ulcer while keeping you mobile.
North Chicago, IllinoisAges 18 years+ - NCT05369052RecruitingPhase 3
New antibiotic for moderate or severe diabetic foot infections
This Phase 3 trial tests a new medicine (contezolid acefosamil, and contezolid) to treat moderate or severe diabetic foot infections. It compares the new treatment to linezolid to see which works better and is safer for adults.
Corona, CaliforniaAges 18 years+ - NCT06383013RecruitingPhase 2
BB-101 for diabetic foot and leg ulcers
This trial tests a new medicine called BB-101 for diabetic ulcers on the lower leg or foot. The goal is to see if it helps these wounds heal faster.
TainanAges 20 years+ - NCT04916457Recruiting
Studying skin germs in diabetes-related foot skin problems
This study collects skin samples from people with and without type 2 diabetes, especially around foot skin problems, to learn how skin “micro-germs” differ. The goal is to better understand what’s going on in diabetic skin lesions and possibly guide future care.
Guangzhou, GuangdongAges 18–80 - NCT06767501Recruiting
Amnion graft for diabetic foot ulcers vs. standard care
This trial tests whether a special amnion membrane graft can help heal diabetic foot ulcers better than standard care alone. If you have a diabetic foot ulcer that hasn't healed after standard treatment, this study may offer a new option.
Roanoke, VirginiaAges 18 years+ - NCT07198061Recruiting
Cold Plasma for Diabetic Foot Ulcers After Leg Artery Treatment
This study tests whether adding cold atmospheric plasma treatment to standard care helps heal foot ulcers in people with diabetes who have recently had a procedure to open blocked leg arteries. The goal is to see if this approach is safe and more effective than current care alone.
Anshan, LiaoningAges 18–80 - NCT07096934RecruitingPhase 1/Phase 2
Testing a new cell treatment for stubborn diabetic foot ulcers
This trial tests a new treatment using special skin cells grown into tiny spheres (spheroids) to help heal diabetic foot ulcers that have not healed with standard care. It aims to see if this treatment is safe and works better than usual care.
Coffs Harbour, New South WalesAges 18–80 - NCT07588503RecruitingPhase 1
FES Cycling With Blood Flow Restriction for Spinal Cord Injury
This study tests a new exercise method combining electrical stimulation (FES) and controlled blood flow restriction while you cycle. It's designed to improve heart health, blood sugar control, and fitness in people with spinal cord injuries.
Toronto, OntarioAges 18–75 - NCT02280733Recruiting
Chronic wound registry for real-world care documentation
This study is a real-world registry that collects information about chronic wounds and ulcers as they’re treated in everyday settings. It may help improve how care is tracked and supported, even if you don’t get a new medicine from the study.
The Woodlands, TexasAges Any age - NCT07581145RecruitingPhase 3
Semaglutide for Faster Healing of Diabetic Foot Ulcers
This study tests whether a diabetes medication called semaglutide can help foot ulcers heal faster in people with type 2 diabetes. If it works, it could offer a new treatment option for a common and serious diabetes complication.
CopenhagenAges 18–90 - NCT07696728Recruiting
Pulsed magnetic field therapy for diabetic foot ulcer sensation
This trial tests whether a painless pulsed electromagnetic field treatment can improve feeling in diabetic foot ulcers. It is designed for people with type 2 diabetes who have had a foot ulcer for a while and have lost some sensation due to nerve damage.
Faisalabad, Punjab ProvinceAges 40–60 - NCT07300163Recruiting
FeetSee: Thermal images for diabetes foot health
This study collects thermal (heat) images of the feet of people with diabetes who have had a healed foot ulcer. The goal is to see if these images can help prevent future foot problems.
VilniusAges 18 years+ - NCT06277362Recruiting
New Leg-Saving Treatment for Critical Limb Ischemia
This study tests a new way to restore blood flow to the leg in people who have wounds or dead tissue on their foot and have run out of other treatment options. It's for those who have already tried angioplasty twice without success or have severely hardened small arteries.
Ancona, AnconaAges 18 years+ - NCT05390892RecruitingPhase 4
Preventing kidney and heart damage in type 2 diabetes
This study tests whether diabetes medicines can help prevent worsening heart and kidney problems in people with type 2 diabetes. You’ll be assigned by chance to one of these medicine types, and your other care will be adjusted for safety.
Huntsville, AlabamaAges 40–80 - NCT07444593Recruiting
Shin bone transport to heal diabetic foot ulcers
This trial tests whether a surgical technique called transverse tibial bone transport (TTT) can help heal chronic diabetic foot ulcers. TTT involves moving a small piece of the shinbone to encourage new blood vessels to grow to the wound, which may help it close.
Jacksonville, FloridaAges 22 years+ - NCT07248631Recruiting
Exercises and mindful walking for diabetic nerve pain
This study tests whether combining foot and ankle exercises with mindful walking can reduce pain and improve mobility in people with diabetic nerve damage in their feet.
Multan, Punjab ProvinceAges 3.3 years–6.3 years - NCT06388603Recruiting
Bioactive glass for diabetic foot bone infection in the forefoot
This trial tests a special glass material (bioactive glass S53P4) placed into the bone after surgery to treat a diabetic foot infection in the forefoot. It may help heal the infection better than standard care.
Monfalcone, GoriziaAges 18–100 - NCT07865208Recruiting
Measuring foot pressure in diabetic patients with partial foot amputation
This study measures the pressure on the bottom of your foot while walking, which may help design better shoes or insoles for people with partial foot amputations due to diabetes.
SingaporeAges 21 years+ - NCT06693180Recruiting
Hyperbaric oxygen therapy for diabetic foot ulcers
This trial is testing whether hyperbaric oxygen therapy (breathing pure oxygen in a pressurized chamber) can help heal diabetic foot ulcers. It is for people with diabetes who have a foot ulcer that is not healing well.
Amsterdam, North HollandAges 18 years+ - NCT04920253Recruiting
Testing a water-jet treatment to heal certain foot and leg wounds
This trial tests a new “micro water jet” device (Debritom+) to help heal specific hard-to-heal wounds in people who can attend frequent visits. If you qualify, you’ll be assigned to the device treatment or standard care and monitored to see how well the wound heals.
Bradenton, FloridaAges 18 years+ - NCT07541196Recruiting
PAW-Hydrogel treatment for long-lasting wound healing
This study tests a special gel called PAW-Hydrogel to help heal chronic wounds (wounds that have not closed after 3+ months). The gel may help wounds close faster by supporting the natural healing process.
Ocoyoacac, State of MexicoAges 18 years+ - NCT07172893RecruitingPhase 4
Dermabind TL for diabetic foot ulcers
This trial tests a new wound dressing called DermaBind TL for people with diabetic foot ulcers. It aims to see if the dressing helps heal these wounds, which can be hard to treat.
DeLand, FloridaAges 18–80 - NCT07116174Recruiting
Testing a new amniotic membrane dressing for diabetic foot ulcers
This study tests a new wound dressing made from amniotic membrane, called Xcell Amnio Matrix, to see if it helps heal diabetic foot ulcers that have not healed with standard treatments. If you qualify, you would receive the dressing along with regular wound care.
Fresno, CaliforniaAges 18 years+
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Common questions
- Are there clinical trials for diabetic foot disease?
- Yes. Clin2 currently lists 87 recruiting diabetic foot disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a diabetic foot disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a diabetic foot disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.