Clinical trials
Efficacy and Safety clinical trials
Below are recruiting efficacy and safety clinical trials, each written for real people, not researchers. We’re tracking 2,824 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07150026RecruitingPhase 1
Testing vorinostat for Pitt Hopkins syndrome
This trial tests whether vorinostat, a medication that may affect gene activity, is safe and helpful for children and young adults with Pitt Hopkins syndrome. Participants take the drug by mouth or feeding tube.
MedellínAges 3–21 - NCT06632613RecruitingPhase 2
Trial of ENN0403 to prevent kidney injury after heart surgery
This study tests a new drug (ENN0403) given during heart surgery to see if it prevents acute kidney injury—a sudden drop in kidney function. The trial is for people who are already at higher risk due to their specific heart surgery and other health factors.
ShanghaiAges 18–85 - NCT07142304Recruiting
A study of compression gloves and boots to prevent chemo nerve damage
This trial is testing a wearable device (gloves and boots) that applies gentle compression to your hands and feet during chemotherapy. It aims to prevent or reduce nerve damage (numbness, tingling, pain) that some chemotherapy drugs can cause.
Poway, CaliforniaAges 18 years+ - NCT07591298RecruitingPhase 2
SYH2070 injection for homozygous familial high cholesterol
This study tests a new injectable medication (SYH2070) designed to lower cholesterol in people with homozygous familial hypercholesterolemia—a genetic condition that causes extremely high cholesterol levels despite treatment. The goal is to see if this drug safely reduces cholesterol better than current options.
Changsha, HunanAges 18 years+ - NCT07579936RecruitingPhase 2
SAL056 bone-strengthening treatment for postmenopausal osteoporosis
This study tests a new injectable medication called SAL056 to strengthen bones and prevent fractures in postmenopausal women with osteoporosis. Researchers want to find the best dose and how often to give it.
Beijing, Beijing MunicipalityAges 45–80 - NCT06631989RecruitingPhase 1/Phase 2
Study of WSD0922-FU for advanced EGFR-mutant lung cancer
This trial tests a new drug called WSD0922-FU for people with advanced non-small cell lung cancer that has a specific EGFR gene change. It aims to see if the drug can help when previous EGFR treatments have stopped working.
Hefei, AnhuiAges 18–75 - NCT07132827RecruitingPhase 3
Study of SHR-1905 for chronic sinusitis with nasal polyps
This trial tests a new injection (SHR-1905) for people with chronic sinusitis and nasal polyps who still have symptoms despite using standard nasal spray treatments. It aims to see if the drug can reduce polyp size and improve symptoms.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT06914583Recruiting
Hyaluronic acid injection for dry, dull facial skin
This trial tests a hyaluronic acid injection to temporarily improve dry skin and dull complexion on the face. You may be able to take part if you are an adult seeking a non-surgical solution for these concerns.
BeijingAges 18–65 - NCT07338344RecruitingPhase 2
Luspatercept with thalidomide for beta-thalassemia patients
This study tests whether a combination of two drugs, luspatercept and thalidomide, can help people with beta-thalassemia who need regular blood transfusions. It aims to reduce the number of transfusions needed.
Shenzhen, GuangdongAges 18–75 - NCT06625957RecruitingPhase 3
NTCB02-1 trial for patients needing IV nutrition
This trial tests an investigational IV nutrition product called NTCB02-1 in patients who need nutrition through a vein (parenteral nutrition) for at least 3 days. It aims to see if it is safe and works well.
Gyeonggi-do, Goyang-siAges 19 years+ - NCT06990529RecruitingPhase 2
Long-term safety and effectiveness of leniolisib for immune problems
This study tests the long-term safety and effectiveness of the drug leniolisib for people with certain immune system disorders. It is for people who have already been in a previous study of this drug and may benefit from continuing treatment.
Bethesda, MarylandAges 12–75 - NCT06753110Recruiting
Long-term safety of OPRA implant for arm amputees
This study checks the long-term safety and how well the OPRA implant (a bone-anchored prosthetic) works for people who have an arm amputation. It is for those who already have the implant and had their second surgery at least six months ago.
Melbourne, VictoriaAges Any age - NCT05042453Recruiting
Long-term follow-up of Splentis for uterine prolapse repair
This trial follows women who have symptoms of uterine prolapse and are getting surgery with a device called Splentis. The study looks at whether Splentis works over the long term and whether it has any important side effects.
ChemnitzAges 18 years+ - NCT06759636RecruitingPhase 3
Comparing two drugs for low platelets from cancer treatment
This trial tests if a new drug called Romiplostim N01 works better than the standard drug Interleukin-11 for raising low platelet counts caused by cancer treatments like chemotherapy or radiation. If you have low platelets from your cancer therapy, you may be able to join.
Nanjing, JiangsuAges 18–75 - NCT07708142RecruitingPhase 3
Testing a new injection for swelling after retinal vein blockage
This trial tests a new medicine called SMO1 for people with vision loss and swelling in the eye caused by a blocked vein in the retina. It involves regular eye injections to see if the medicine can reduce swelling and improve vision.
Seoul, Gangdong-guAges 19 years+ - NCT07269106RecruitingPhase 4
Testing anrikefon for pain relief after eye surgery
This trial tests a new painkiller called anrikefon for people having eye surgery under general anesthesia. It aims to see if it's safe and effective for controlling pain after the procedure.
Guangzhou, GuangdongAges 18–70 - NCT07505199RecruitingPhase 1
Immune cell therapy for advanced heart failure from blocked arteries
This early-phase study tests a new type of immune cell therapy (CAR-DC) for people with advanced heart failure due to blocked arteries. It aims to see if the treatment is safe and may help improve heart function.
Hangzhou, Zhejiang / 浙江Ages 18–75 - NCT06708260RecruitingPhase 2
Study of ENN0403 for diabetic macular edema
This trial tests a new eye drop or injection called ENN0403 for people with diabetic macular edema (swelling in the back of the eye due to diabetes). The goal is to see if it can improve vision and reduce swelling.
Tianjin, Tianjin MunicipalityAges 18–80 - NCT07484061Recruiting
Drinkable supplement for hair loss in women on weight-loss drugs
This trial tests if a special drinkable supplement can help prevent or reduce hair loss in women who are taking a GLP-1 or GIP receptor agonist (a type of weight-loss or diabetes medication). The study looks for women who have just started this medication or have been on it for less than 3 months.
Madrid, MadridAges 35 years+ - NCT07712523RecruitingPhase 2
Testing QY201 tablets for non-segmental vitiligo
This trial tests an experimental oral tablet called QY201 to see if it can improve vitiligo (white patches on the skin). It is for adults with non-segmental vitiligo, regardless of whether the patches are currently growing or stable.
Shenyang, LiaoningAges 18–65 - NCT07241169RecruitingEarly Phase 1
Gene therapy trial for ABCA4-related retinal disease
This trial tests a new gene therapy called ZVS106e for people with inherited retinal degeneration caused by changes in both copies of the ABCA4 gene. The therapy aims to slow or stop vision loss, and the study will check if it is safe and if it works.
Beijing, Beijing MunicipalityAges 8 years+ - NCT07672561RecruitingPhase 3
Testing a new pill for moderate to severe plaque psoriasis
This study tests an experimental pill called WD-890 to see if it can help people with moderate to severe plaque psoriasis. The pill is compared to a placebo (a pill with no medicine) to check if it is safe and works well.
Nanjing, JiangsuAges 18–75 - NCT07184801RecruitingPhase 3
Comparing two sedatives for medical thoracoscopy
This trial tests if dexmedetomidate or midazolam is safer and works better for sedation during a medical thoracoscopy, a procedure to look inside the chest. It may help you if you need this procedure for an unclear pleural effusion.
Chandigarh, ChandigarhAges 12–90 - NCT07667803RecruitingPhase 3
Study of elecoglipron for weight loss in obesity or overweight
This trial tests an investigational drug called elecoglipron to see if it helps people with obesity or overweight lose weight. It may be an option if you have a high body mass index or weight-related health issues like high blood pressure or prediabetes.
Birmingham, AlabamaAges 18 years+
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Common questions
- Are there clinical trials for efficacy and safety?
- Yes. Clin2 currently lists 2,824 recruiting efficacy and safety studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a efficacy and safety trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a efficacy and safety trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.