Clinical trials
Epilepsy clinical trials
Below are recruiting epilepsy clinical trials, each written for real people, not researchers. We’re tracking 325 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03893916Recruiting
MEG vs EEG tests to find the epilepsy trigger before surgery
This study compares two brain tests—MEG and routine scalp EEG—to pinpoint where seizures start before surgery. It may help doctors choose the safest and most effective plan if you’re being considered for an epilepsy procedure.
BronAges 18–60 - NCT07594119RecruitingPhase 3
Testing RAP-219 to reduce seizures in focal epilepsy
This study tests a new medication called RAP-219 to see if it can reduce seizure frequency in adults with focal epilepsy (seizures starting in one area of the brain). You'll take the medication alongside your current seizure drugs and track your seizures daily using an app.
Huntsville, AlabamaAges 18–75 - NCT07764718Recruiting
Brain stimulation for adults with drug-resistant epilepsy
This trial tests a new type of brain stimulation to find and treat the area causing seizures in adults whose seizures don't improve with medication. It is done during a standard monitoring procedure to help doctors better target treatment.
Durham, North CarolinaAges 18 years+ - NCT07600736RecruitingPhase 2
Safety study of ABS-1230 for children with KCNT1 epilepsy
This trial tests a new drug called ABS-1230 in children and young adults with KCNT1-related epilepsy, a rare genetic form of epilepsy. The study will check if the drug is safe and if it helps reduce seizures.
Hackensack, New JerseyAges 1 month–21 years - NCT07696442Recruiting
Music therapy for sleep in children with epilepsy
This study tests whether listening to music can help children with epilepsy sleep better. It involves wearing a small device to track sleep and completing questionnaires.
Taipei, TaiwanAges 1.5 years–9 years - NCT04076449Recruiting
MRI measurements for epilepsy from a single brain blood vessel lump
This study uses special MRI scans to measure brain changes in people whose seizures are related to one cerebral cavernous malformation (a type of abnormal blood vessel in the brain). It aims to find a measurable “biomarker” from MRI that may help understand the epilepsy and the brain structure around it.
Beijing, Beijing MunicipalityAges 18–70 - NCT04144439RecruitingPhase 4
GABA treatment for ADHD and seizures in children with epilepsy
This trial studies whether adding GABA (a substance that affects brain signaling) can help children who have both epilepsy (seizures) and ADHD. If it works, it may reduce symptoms related to either seizures, ADHD, or both.
TantaAges 4–18 - NCT01403402Recruiting
Study of congenital muscle disease patients and their families
This trial collects health information from patients with certain inherited (genetic) muscle diseases and from their families. It may help researchers better understand the disease and improve care by learning what symptoms and treatments patients experience over time.
Lakewood, CaliforniaAges Any age - NCT05307146Recruiting
Brain activity study during treatment for epilepsy
This study measures brain activity in people with epilepsy while doctors place temporary electrodes inside the brain. It may help researchers better understand seizures and how to improve treatment.
LeuvenAges 18–90 - NCT02821260Recruiting
Evaluating epilepsy surgery results in children at a French hospital
This study looks at how well epilepsy surgery works for infants and children treated at the Rothschild Foundation. It mainly depends on whether your child is already scheduled/being treated there and whether you agree to participate.
ParisAges Up to 18 years - NCT00041600Recruiting
Brain Development and Genetic Study for Family Members
This research study investigates how genetic factors affect brain development and function in families where members have brain malformations, intellectual disability, or autism. Researchers hope to identify genetic causes that could lead to better understanding and future treatments.
Boston, MassachusettsAges Any age - NCT06212609Recruiting
Personalized brain stimulation for kids with hard-to-control epilepsy
This trial tests a personalized brain stimulation method (transcranial electrical stimulation) to reduce seizures in children with hard-to-control partial epilepsy. It aims to find the best stimulation spot and settings for each patient by using advanced brain scans.
AmiensAges 1–18 - NCT03644732Recruiting
Study of brain activity during epilepsy testing using SEEG
This study maps how thinking and memory work by recording brain signals during a presurgical epilepsy workup. It may help doctors better understand drug-resistant focal epilepsy and improve how they plan treatment.
GrenobleAges 18–65 - NCT06321822Recruiting
Genetic diagnosis and personalized medicine for epilepsy patients
This study aims to find genetic causes of epilepsy and use that information to personalize your care. It involves analyzing your DNA to look for gene changes that may be linked to your seizures.
MilanAges Any age - NCT04945213RecruitingPhase 3
Biperiden to prevent seizures after traumatic brain injury
This trial tests whether biperiden can lower the chance of developing epilepsy after an acute traumatic brain injury (with bleeding or bruising seen on CT). If you qualify, you would get the medicine or a placebo soon after the injury, and researchers will compare outcomes.
Fortaleza, CearáAges 18–75 - NCT06334029Recruiting
Observing brain connections in epilepsy
This study is observing how the brain's connections and activity work in people with epilepsy. It uses MRI scans and EEG recordings to learn more about the condition, which may help improve future treatments.
Conegliano, TrevisoAges 6–65 - NCT05450822Recruiting
Personalized testing to guide treatment for epilepsy
This trial uses detailed brain tests to better match people with epilepsy to the right treatment. It may help by using “precision medicine” methods to understand what in the brain is driving seizures.
CopenhagenAges 16–55 - NCT04126369Recruiting
Mindfulness program to improve quality of life in drug-resistant epilepsy
This trial tests whether a mindfulness training program can improve quality of life for people with drug-resistant epilepsy. It looks at whether learning mindfulness skills helps you cope day-to-day alongside your usual treatment.
GrenobleAges 18 years+ - NCT05637086RecruitingPhase 2
Test pentoxifylline plus celecoxib for grand mal epilepsy on phenytoin
This Phase 2 study tests whether adding two medicines—pentoxifylline and celecoxib—to current phenytoin treatment is safe and may help people with grand mal (generalized) epilepsy. It focuses mainly on safety while you stay on a single epilepsy medicine.
Al MansurahAges 18–75 - NCT07723963RecruitingPhase 2/Phase 3
Study of JZP926 for juvenile myoclonic epilepsy
This study tests an investigational drug called JZP926 (a type of cannabinoid) to see if it can reduce the number of days with myoclonic seizures in people with juvenile myoclonic epilepsy. If you have this condition and are at least 10 years old, you might be able to join.
Phoenix, ArizonaAges 10 years+ - NCT05845255Recruiting
Test wearable monitoring for epilepsy quality of life and safety
This study tests a wearable device that records seizure-related information to understand how epilepsy affects daily life and safety. It may help your care team better track seizures in real-world settings and understand quality-of-life changes.
KorkAges 12–65 - NCT06053671Recruiting
Understanding genetics in focal epilepsy brain tissue
This study is looking at brain tissue from people with a specific type of epilepsy (Focal Cortical Dysplasia Type II). The goal is to understand what causes the seizures and how they develop, which may help improve future treatments.
LondonAges Any age - NCT07656857Recruiting
Flexible brain sensor study for epilepsy surgery
This trial tests a new flexible brain sensor to help guide surgery for people with drug-resistant focal epilepsy. It aims to find exactly where seizures start so surgeons can remove that area safely.
Beijing, Beijing MunicipalityAges 3–60 - NCT07663240Enrolling by invitation
Program to help women with epilepsy reduce ER visits
This study is for Black or Hispanic women with epilepsy who often go to the emergency room for seizures. It aims to help reduce ER visits by connecting you with better follow-up care and support.
Atlanta, GeorgiaAges 18 years+
Hear when a new Epilepsy trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for epilepsy?
- Yes. Clin2 currently lists 325 recruiting epilepsy studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a epilepsy trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a epilepsy trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.