Clinical trials
ExtraCorporeal Membrane Oxygenation (ECMO) clinical trials
Below are recruiting extracorporeal membrane oxygenation (ecmo) clinical trials, each written for real people, not researchers. We’re tracking 50 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06560164Recruiting
Comparing blood transfusion levels in ECMO patients
This trial tests whether giving more or fewer red blood cell transfusions is better for adult patients on ECMO (a machine that helps your heart and lungs work). The goal is to find the best transfusion approach to improve outcomes.
Vienna, State of ViennaAges 18 years+ - NCT05237232Recruiting
MRI study of blood vessel changes after ECMO in infants
This study uses a brain MRI with a special blood-vessel scan to see how circulation changes after a life-support machine called ECMO in young children. It may help doctors better understand what happens in the brain after ECMO and improve care.
ParisAges Up to 17 years - NCT06276010Recruiting
Nafamostat mesilate for blood thinning in ECMO patients
This trial tests a medicine called nafamostat mesilate to prevent blood clots in patients who need ECMO (a machine that helps your heart and lungs) after heart surgery. It may offer a safer way to thin the blood compared to standard treatments.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06275555Recruiting
Bivalirudin for blood thinning in ECMO patients
This trial tests if bivalirudin is a safe and effective blood thinner for people on ECMO, a machine that helps your heart and lungs. You may be eligible if you need this therapy and have no past reactions to similar medicines.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06038162Recruiting
Kidney treatment for patients on ECMO
This study compares two ways of giving kidney dialysis to patients who are on a heart-lung bypass machine (ECMO). It aims to find which method works better for filtering the blood.
BordeauxAges 18 years+ - NCT05959252RecruitingPhase 2
Bivalirudin vs heparin for blood thinning during ECMO
This Phase 2 trial compares two blood-thinning medicines—bivalirudin and heparin—in people on ECMO (a machine that supports breathing and/or circulation). It aims to see which medicine works better and is safer while you are connected to the ECMO circuit.
Sydney, New South WalesAges 18 years+ - NCT05830721Recruiting
Monitoring leg pressure in adults on life-support
This trial tests a device that continuously measures pressure in an arm or leg to help detect compartment syndrome in people on a heart-lung machine (VA-ECMO). It may help clinicians act sooner if pressure becomes dangerous, potentially reducing complications.
Baltimore, MarylandAges 18 years+ - NCT05699005RecruitingPhase 1
Personalized or standard blood transfusion during heart-lung machine
This trial tests whether giving blood in a personalized way, instead of a standard approach, is better for people on a heart-lung bypass machine (VA-ECMO) for heart-related shock. It may help find a safer blood transfusion strategy while you are critically ill.
Lille, NORDAges 18 years+ - NCT03593408Recruiting
Study drug levels in children on ECMO
This study measures how sedating and pain medicines move through the body in children who are supported by ECMO (a heart-lung machine). It may help doctors choose safer and more effective dosing for sedation and pain control during ECMO.
Boston, MassachusettsAges birth–17 years - NCT04709432Recruiting
Study of ECMO care for children in China
This study looks at children (ages 1 day to 18 years) in mainland China who were treated with ECMO during the past 10 years. It aims to understand how ECMO was used and how care outcomes may have differed for children.
Shanghai, Shanghai MunicipalityAges 1 day–18 years - NCT04273607RecruitingPhase 2/Phase 3
Test an ECMO approach without blood thinners for lung failure
This trial studies whether people on a breathing machine called VV-ECMO can be managed without routine blood thinners, to reduce bleeding risk. It is meant for adults with severe lung failure (ARDS) and checks that it is safe for you to avoid anticoagulation.
Toronto, OntarioAges 18 years+ - NCT03948048Recruiting
ECMO timing study for children with hard-to-treat septic shock
This trial looks at whether and when a heart-lung machine called ECMO should be used in children whose septic shock is not responding to standard treatment. It may help doctors choose the best timing to improve survival and recovery in the PICU.
ShanghaiAges 4 weeks–18 years - NCT06862700Recruiting
Less vasopressors for heart shock on ECMO
This trial is studying whether using less of the medicines that raise blood pressure (vasopressors) can help people with severe heart failure who are on a heart-lung machine (ECMO) survive. It may answer if a gentler approach is safer.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07016685Recruiting
ECMO outcomes after emergency chest surgery
This study looks at how well patients recover after needing a heart-lung bypass machine (VV-ECMO) during or right after emergency chest surgery. It aims to understand what affects their prognosis.
AmiensAges 18 years+ - NCT05814094Recruiting
Testing a red blood transfusion approach during ECMO
This study looks at whether giving red blood cell transfusions in a specific way is practical and safe for people receiving ECMO (a heart-lung support machine). It’s mainly a feasibility study, meaning the goal is to see if the plan can be carried out smoothly and safely.
Camperdown, New South WalesAges 18 years+ - NCT06469801Recruiting
Checking for brain injury in children on ecmo with a portable mri
This study uses a small, portable MRI machine to look for brain injury in children on ECMO (a life-support machine for the heart and lungs). The hope is to spot problems early so they can be treated sooner.
Kansas City, MissouriAges birth–17 years - NCT07156669Recruiting
Safety and Performance of Novalung ECMO Kit and Xenios 2.0
This study is testing how well a special ECMO device (Novalung ultimate kit with Xenios 2.0) works for adults in the hospital and during ground transport. If you already need ECMO with this specific device, you may be able to join.
Erfurt, BavariaAges 18 years+ - NCT05440851Recruiting
Testing different treatments for severe breathing failure in ICU
This platform trial studies which treatment works best for adults with sudden, severe breathing failure needing oxygen or a breathing machine in the ICU. It may help patients by matching them to the most appropriate treatment strategy and tracking outcomes to improve care.
Tucson, ArizonaAges 18 years+ - NCT07127718RecruitingPhase 2
Preventing complications from leptospirosis
This trial tests ways to prevent early and late complications of leptospirosis, a bacterial infection. It aims to offer treatments that may reduce the risk of serious problems like kidney failure or breathing difficulties.
Manila, National Capital RegionAges 18–60 - NCT05574296RecruitingPhase 1
Test hydrogen gas for children needing emergency heart resuscitation
This early safety study tests whether “hydrogen” can be given to children during emergency heart resuscitation that isn’t improving with standard efforts. It’s meant to see if the treatment is safe and feasible for a very specific, life-threatening situation.
Washington D.C., District of ColumbiaAges Any age - NCT06750536Recruiting
Safety study of a new lung support device for small children
This trial is testing a new device (MiniLung Petite Kit) for babies and young children with severe lung or heart failure. The device helps oxygenate the blood and remove carbon dioxide, giving the lungs and heart a chance to rest and heal.
Bonn, North Rhine-WestphaliaAges Up to 8 months - NCT06696235RecruitingPhase 4
Comparing fast vs standard kidney therapy for heart shock patients on ECMO
This trial tests whether starting kidney replacement therapy faster or at the usual time improves outcomes for people with severe heart failure (cardiogenic shock) who are on a heart-lung machine (ECMO) and develop sudden kidney injury.
SeoulAges 19 years+ - NCT06526533RecruitingPhase 3
Red blood cell transfusion thresholds for ECMO patients
This trial is testing whether a higher or lower threshold for red blood cell transfusions is better for people on ECMO (a heart-lung machine). It aims to find the safest way to manage transfusions during ECMO treatment.
Camperdown, New South WalesAges Any age - NCT02851758Recruiting
Autologous mitochondria treatment for critically ill heart children on ECMO
This trial looks at giving a child their own mitochondria to help protect the heart from injury caused by reduced blood flow. It is for children with serious heart problems who are on a heart-lung machine and may have signs of ischemia (reduced blood flow damage).
Boston, MassachusettsAges Up to 17 years
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Common questions
- Are there clinical trials for extracorporeal membrane oxygenation (ecmo)?
- Yes. Clin2 currently lists 50 recruiting extracorporeal membrane oxygenation (ecmo) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a extracorporeal membrane oxygenation (ecmo) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a extracorporeal membrane oxygenation (ecmo) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.