Clinical trials
ExtraCorporeal Membrane Oxygenation (ECMO) clinical trials
Below are recruiting extracorporeal membrane oxygenation (ecmo) clinical trials, each written for real people, not researchers. We’re tracking 51 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06560164Recruiting
Comparing blood transfusion levels in ECMO patients
This trial tests whether giving more or fewer red blood cell transfusions is better for adult patients on ECMO (a machine that helps your heart and lungs work). The goal is to find the best transfusion approach to improve outcomes.
Brussels, Brussels CapitalAges 18 years+ - NCT06593756Recruiting
Heart-Lung Support and Fluid Response Study
This study watches how your body responds to fluids while on VA ECMO (a heart-lung machine). The goal is to improve care for people needing this support.
ViennaAges 18–75 - NCT06593717Recruiting
Monitoring blood flow in VV-ECMO patients
This study tests how doctors can monitor your blood flow and fluid needs while you are on VV-ECMO. It involves a simple maneuver where your legs are raised to see if your heart needs more fluid.
ViennaAges 18–75 - NCT06766006Recruiting
Heart-lung machine left ventricle unloading study
This study looks at how to best relieve pressure on the heart while a heart-lung machine is helping to pump blood. It includes anyone who needs this support.
MaastrichtAges 1 day–80 years - NCT06792643RecruitingPhase 2
Cangrelor for heart attack patients on heart-lung support
This trial tests whether adding a fast-acting anti-clotting drug (cangrelor) helps people having a massive heart attack who need a heart-lung machine (VA-ECMO). The goal is to see if it reduces clotting risks without causing dangerous bleeding.
Milan, ItalyAges 18 years+ - NCT06814340RecruitingPhase 3
CPAP on ECMO for severe lung failure
This trial is for people with severe lung failure (ARDS) who are already on a life-support machine called VV-ECMO. It tests whether adding a special breathing tube (CPAP) can help their lungs heal better.
BobignyAges 18 years+ - NCT06868823Recruiting
Blood thinners during lung transplant bypass
This study compares two different blood thinners (UFH and LMWH) used during heart-lung bypass (ECMO) for double lung transplant patients. The goal is to see which one works better and is safer.
Prague, Czech RepublicAges 18 years+ - NCT07032987Recruiting
Improving sedation with a new care plan for ICU patients
This trial tests a new sedation protocol for adults in intensive care who need strong pain relief or sedation medicines. It aims to make sedation safer and more comfortable, and includes people on ECMO (a heart-lung machine) or a ventilator (breathing machine) for severe breathing problems.
London, LondonAges 18–100 - NCT07041086Recruiting
Prehospital ECMO for cardiac arrest
This trial tests whether giving ECMO (a heart-lung machine) to people in cardiac arrest before they reach the hospital can improve survival. It might be an option if you had a witnessed heart attack and received CPR quickly.
Ostrava, Moravian-Silesian RegionAges 18–70 - NCT07113769Recruiting
Biomarkers and platelets in CPR patients
This trial is studying the blood biomarkers and platelet characteristics in patients who receive CPR and are then placed on a heart-lung bypass machine (ECPR). It aims to understand how these biological markers relate to patient outcomes.
Zhengzhou, HenanAges 18 years+ - NCT05699005RecruitingPhase 1
Personalized or standard blood transfusion during heart-lung machine
This trial tests whether giving blood in a personalized way, instead of a standard approach, is better for people on a heart-lung bypass machine (VA-ECMO) for heart-related shock. It may help find a safer blood transfusion strategy while you are critically ill.
Lille, NORDAges 18 years+ - NCT07309029Recruiting
ECMO support during high-risk TAVR heart valve procedure
This trial tests whether placing patients on ECMO (a heart-lung support machine) before a high-risk TAVR valve replacement can improve safety and outcomes. It is for people who are at very high risk due to low blood pressure, severe heart or lung problems, or complex valve anatomy.
Detroit, MichiganAges 18–100 - NCT05814094Recruiting
Testing a red blood transfusion approach during ECMO
This study looks at whether giving red blood cell transfusions in a specific way is practical and safe for people receiving ECMO (a heart-lung support machine). It’s mainly a feasibility study, meaning the goal is to see if the plan can be carried out smoothly and safely.
Camperdown, New South WalesAges 18 years+ - NCT07016685Recruiting
ECMO outcomes after emergency chest surgery
This study looks at how well patients recover after needing a heart-lung bypass machine (VV-ECMO) during or right after emergency chest surgery. It aims to understand what affects their prognosis.
AmiensAges 18 years+ - NCT06862700Recruiting
Less vasopressors for heart shock on ECMO
This trial is studying whether using less of the medicines that raise blood pressure (vasopressors) can help people with severe heart failure who are on a heart-lung machine (ECMO) survive. It may answer if a gentler approach is safer.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06469801Recruiting
Portable MRI for brain injury in children on ECMO
This study uses a portable MRI to look for brain injuries in children on ECMO (a heart-lung support machine). It may help doctors detect problems early and improve care.
Kansas City, MissouriAges birth–17 years - NCT06369584Recruiting
Prone Position for Children on ECMO with Severe ARDS
This trial tests if lying face-down (prone position) helps children with severe ARDS who are already on ECMO, a machine that supports the heart and lungs. It aims to see if this position improves recovery.
Beijing, Beijing MunicipalityAges 1 month–18 years - NCT05440851Recruiting
Testing different treatments for severe breathing failure in ICU
This platform trial studies which treatment works best for adults with sudden, severe breathing failure needing oxygen or a breathing machine in the ICU. It may help patients by matching them to the most appropriate treatment strategy and tracking outcomes to improve care.
Tucson, ArizonaAges 18 years+ - NCT02851758Recruiting
Autologous mitochondria treatment for critically ill heart children on ECMO
This trial looks at giving a child their own mitochondria to help protect the heart from injury caused by reduced blood flow. It is for children with serious heart problems who are on a heart-lung machine and may have signs of ischemia (reduced blood flow damage).
Boston, MassachusettsAges Up to 17 years - NCT04198792Recruiting
Finding outcomes after ECMO for heart-related emergencies
This study looks at what helps determine survival and better brain function after people are treated with ECMO, a heart-lung support machine. It may help doctors understand who is most likely to do well after this kind of emergency treatment.
GothenburgAges 16 years+ - NCT05426083Recruiting
Test effects of VA-ECMO on the heart during cardiogenic shock
This study looks at how a heart-support machine called VA-ECMO affects heart function in people with cardiogenic shock caused by a sudden heart artery problem. Your care team may use standard VA-ECMO, and the study will measure the heart’s response to support.
Minneapolis, MinnesotaAges 18 years+ - NCT05574296RecruitingPhase 1
Test hydrogen gas for children needing emergency heart resuscitation
This early safety study tests whether “hydrogen” can be given to children during emergency heart resuscitation that isn’t improving with standard efforts. It’s meant to see if the treatment is safe and feasible for a very specific, life-threatening situation.
Washington D.C., District of ColumbiaAges Any age - NCT06526533RecruitingPhase 3
Red blood cell transfusion thresholds for ECMO patients
This trial is testing whether a higher or lower threshold for red blood cell transfusions is better for people on ECMO (a heart-lung machine). It aims to find the safest way to manage transfusions during ECMO treatment.
Camperdown, New South WalesAges Any age - NCT06696235RecruitingPhase 4
Comparing fast vs standard kidney therapy for heart shock patients on ECMO
This trial tests whether starting kidney replacement therapy faster or at the usual time improves outcomes for people with severe heart failure (cardiogenic shock) who are on a heart-lung machine (ECMO) and develop sudden kidney injury.
SeoulAges 19 years+
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Common questions
- Are there clinical trials for extracorporeal membrane oxygenation (ecmo)?
- Yes. Clin2 currently lists 51 recruiting extracorporeal membrane oxygenation (ecmo) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a extracorporeal membrane oxygenation (ecmo) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a extracorporeal membrane oxygenation (ecmo) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.