Clinical trials
Heart failure clinical trials
A condition where the heart can’t pump blood as well as it should. We’re tracking 949 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05960968Recruiting
Hospital heart failure registry for adults in Santiago
This is a registry study that collects information from adults hospitalized for heart failure in Santiago. It aims to better understand heart failure in real-world patients, including differences by sex, by tracking what happens during the hospital stay.
Santiago, Santiago MetropolitanAges 18 years+ - NCT06683001Recruiting
National heart failure registry
This study is creating a registry of people with chronic heart failure to better understand the condition. If you have any stage of chronic heart failure, you may be able to join.
MoscowAges 18 years+ - NCT06659393Recruiting
Entresto in children with chronic heart failure
This study is for children with chronic heart failure who are starting Entresto for the first time. It helps doctors learn how well the medicine works and how safe it is for kids.
Ōbu, Aichi-kenAges 1–17 - NCT06285760Recruiting
Acetazolamide for fluid removal in acute heart failure
This study tests whether adding acetazolamide (a different type of water pill) to your current treatment helps remove extra fluid from your body more effectively when you are in the hospital for heart failure.
MadridAges Any age - NCT06209359RecruitingPhase 1
Testing a second diuretic for heart failure patients
This trial tests whether adding a second type of diuretic (water pill) can help people with heart failure who don't respond well to their current diuretic. It aims to find better ways to manage fluid buildup.
New Haven, ConnecticutAges 18 years+ - NCT06019169Recruiting
Yoga for Heart Failure: Improving Quality of Life
This study tests if practicing yoga can improve quality of life and well-being for people with stable heart failure. You can join whether you are new to yoga or have done a little before.
ParisAges 18 years+ - NCT05753059RecruitingPhase 1
Study why some water pills stop working in heart failure
This Phase 1 study looks at why “water pills” (diuretics) like bumetanide may not remove fluid as expected in people with heart failure. The results may help clinicians improve treatment strategies for fluid control in the future.
New Haven, ConnecticutAges 18 years+ - NCT05433220Recruiting
Messaging to doctors about treating heart failure
This study tests whether sending guidance messages to your cardiologist improves how heart failure care is provided. It may help patients get the right medication plan, if they are not already on the strongest versions of the standard treatments.
Falls Church, VirginiaAges 18 years+ - NCT05323487RecruitingPhase 1
Study why water pills (diuretics) stop working in heart failure
This Phase 1 study looks at why “water pills” sometimes stop relieving fluid overload in people with heart failure. It may help researchers understand the causes of diuretic resistance and improve future treatment for fluid management.
New Haven, ConnecticutAges 18 years+ - NCT02898181Recruiting
Ear stimulation for heart failure in hospital
This study tests a gentle electrical stimulation on the ear to see if it can help people with heart failure feel better while they are in the hospital. It might help reduce symptoms and improve heart function.
Oklahoma City, OklahomaAges 18–80 - NCT07634640RecruitingEarly Phase 1
Testing an Inflammation Treatment for Heart Failure
This early-stage trial tests a new approach to treat heart failure with preserved ejection fraction (HFpEF)—a type of heart failure where the heart's pumping strength is normal, but it doesn't relax properly. Researchers believe inflammation plays a role and want to see if targeting it can help patients feel better and function more easily.
Gainesville, FloridaAges 18–85 - NCT04329234Recruiting
Heart failure registry study of hospitalized adults
This study collects information from adults hospitalized with heart failure to better understand the condition and outcomes. It may help doctors improve care over time by tracking symptoms, test results, and treatments.
SeongnamAges 18 years+ - NCT02537769Recruiting
Surgery to fix a leaky tricuspid valve in LVAD patients
This study looks at whether fixing a mildly leaky tricuspid valve during LVAD surgery improves outcomes for people with advanced heart failure. It’s mainly aimed at patients who are already scheduled to receive an implantable LVAD.
Seattle, WashingtonAges 18 years+ - NCT05089149Recruiting
Check how lung ultrasound helps manage heart failure congestion
This study looks at people with long-term worsening heart failure who are coming to the hospital for a planned visit, to see how checking “congestion” (fluid buildup) may guide care. It may help the team understand whether lung ultrasound can better assess who needs treatment changes.
Vandœuvre-lès-NancyAges 18 years+ - NCT07775976Enrolling by invitation
Whole-heart checkup with a wearable heart monitor
This study looks at how well a wearable heart monitor and special software can check the health of your whole heart and assess your risk of future heart problems. It may help doctors create more personalized care plans.
Pasadena, CaliforniaAges 18 years+ - NCT06475105RecruitingPhase 4
Acetazolamide and Furosemide for Acute Heart Failure
This trial tests whether adding an oral water pill (acetazolamide) to standard IV furosemide helps people with acute heart failure who have fluid overload. It aims to see if the combination improves outcomes better than furosemide alone.
Semarang, Central JavaAges 18 years+ - NCT07689760Enrolling by invitation
Ai tool to predict heart failure hospital visits
This study uses a smartphone app to track your heart failure and predict when you might need to go to the hospital. It aims to help you stay healthier and avoid urgent hospital stays.
EnschedeAges 18 years+ - NCT07664748Recruiting
Voice check-ins for heart failure monitoring
This study tests whether analyzing your voice during routine check-ins can help monitor heart failure. You'll use a special app or device to talk to a virtual assistant, which may help detect early signs of worsening heart failure.
Milan, ItaAges 18 years+ - NCT06207383Recruiting
Comparing heart treatments for atrial fibrillation and heart failure
This study compares two treatments for people with atrial fibrillation and heart failure: one is a procedure to fix the irregular heartbeat (AF ablation), and the other involves a different type of pacing for the heart. It aims to find which approach helps you feel better and stay out of the hospital.
GrazAges 60 years+ - NCT07567001RecruitingPhase 3
Testing NNC0487-0111 for Heart Failure and Obesity
This study tests whether a new medication called NNC0487-0111 can help people with heart failure who also have obesity. Researchers will compare it to a placebo (inactive pill) to see if it improves heart function and overall health.
Alexander City, AlabamaAges 18 years+ - NCT07563153Recruiting
Pacemaker Pacing Strategies for Heart Failure Patients
This study tests whether optimized pacemaker settings can improve heart function and symptoms in heart failure patients who need a pacemaker for a slow heartbeat. The goal is to find the best way to program the pacemaker to help your heart work better.
Seoul, SeoulAges 19 years+ - NCT07499661Recruiting
Study of blood clots in the lungs with heart failure
This study looks at whether a blood clot in the lungs (pulmonary embolism) is a hidden cause in patients who are hospitalized for acute heart failure. It involves additional imaging tests to find a clot if present, which could change your treatment.
AgenAges 18 years+ - NCT07439159Recruiting
Heart ultrasound to predict outcomes in hospitalized heart failure
This study uses a heart ultrasound (echocardiogram) to predict outcomes in people hospitalized for sudden heart failure. If you are receiving IV fluid-removing medication, the results may help your doctors understand your condition better.
IstanbulAges 18 years+ - NCT07391956Recruiting
Palliative care for advanced heart failure or cancer
This study tests whether special supportive care (called tiered palliative care) can help people with advanced heart failure or certain advanced cancers feel better and have fewer hospital visits. If you live in Manhattan or Queens, speak English or Spanish, and meet the other requirements, you may be able to join.
Astoria, New YorkAges 18 years+
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Common questions
- Are there clinical trials for heart failure?
- Yes. Clin2 currently lists 949 recruiting heart failure studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a heart failure trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a heart failure trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.