Clinical trials
Heart failure clinical trials
A condition where the heart can’t pump blood as well as it should. We’re tracking 982 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07617376RecruitingPhase 4
Flu shot before leaving hospital after heart problems
This study tests whether giving a flu vaccine to patients before they leave the hospital after a heart condition improves their health. The vaccine may help protect your heart and prevent serious flu complications while you recover.
WroclawAges 18 years+ - NCT07650669Recruiting
Using Wearable Devices to Monitor Heart Health
This study asks heart failure patients to wear a fitness tracker (like Fitbit or Apple Watch) and use a smartphone app called HeartBit to share health data with researchers. The goal is to learn whether tracking daily activity, heart rate, and sleep can help catch heart problems early or improve care.
Cleveland, OhioAges 18–85 - NCT07485816Enrolling by invitation
Heart-brain oxygen and thinking changes in heart failure
This study looks at how well your heart and brain work together to use oxygen, and how that relates to changes in thinking and memory for people with heart failure.
Kunming, YunnanAges 18–70 - NCT07166965Enrolling by invitation
Supplement for Heart Failure: Ketones and Hawthorn
This trial tests whether adding a supplement containing ketones and hawthorn extract can help people with heart failure feel better and improve their heart function. You will take the supplement daily and have imaging scans and exercise tests to monitor your progress.
Philadelphia, PennsylvaniaAges 18 years+ - NCT03984591Enrolling by invitationPhase 4
Compare spironolactone vs eplerenone for heart failure patients
This study uses Denmark’s heart failure registry to compare two common tablet medicines—spironolactone and eplerenone—for people with symptomatic systolic heart failure. It aims to see which one leads to better health outcomes over time.
CopenhagenAges Any age - NCT04782232Recruiting
Study of a new blood tube for heart pump patients
This registry study checks whether a new venous blood tube used with a heart pump is safe and practical for people whose right heart is failing and who may need a heart transplant. If you qualify, your care team would monitor how the device works over time.
MunichAges Any age - NCT07714252Enrolling by invitation
Virtual palliative care team for veterans with heart or lung disease
This study tests a virtual team of nurses and social workers who provide palliative care to veterans with heart failure, COPD, or interstitial lung disease. The goal is to improve quality of life by offering extra support at home.
Phoenix, ArizonaAges 18 years+ - NCT06659393Recruiting
Entresto in children with chronic heart failure
This study is for children with chronic heart failure who are starting Entresto for the first time. It helps doctors learn how well the medicine works and how safe it is for kids.
Ōbu, Aichi-kenAges 1–17 - NCT06683001Recruiting
National heart failure registry
This study is creating a registry of people with chronic heart failure to better understand the condition. If you have any stage of chronic heart failure, you may be able to join.
MoscowAges 18 years+ - NCT07667452Recruiting
AI patch study for heart failure recognition
This trial tests a new AI computer model that uses a single feature from a wearable patch to help recognize heart failure more easily. If you have heart failure with moderate to severe symptoms, this study may help improve how we monitor your condition.
Hangzhou, ZhejiangAges 18 years+ - NCT06019169Recruiting
Yoga for Heart Failure: Improving Quality of Life
This study tests if practicing yoga can improve quality of life and well-being for people with stable heart failure. You can join whether you are new to yoga or have done a little before.
ParisAges 18 years+ - NCT06586008Recruiting
Heart failure ultrasound and recovery study
This trial uses a special ultrasound scoring system to see how well people with a certain type of heart failure (weak heart pumping) are doing. It looks at whether this score can predict how their recovery goes.
Semarang, Central of JavaAges 18–70 - NCT07372040RecruitingPhase 2
Adding a Water Pill for Heart Failure in the Hospital
This trial tests if adding a diuretic (water pill) called acetazolamide to usual care can help you get rid of extra fluid faster while you are in the hospital for worsening heart failure.
TantaAges 18 years+ - NCT02898181Recruiting
Ear cartilage stimulation for sudden heart failure worsening
This trial tests whether a gentle stimulation near your ear (on the tragus, a small ear area) can help people whose heart failure has recently gotten worse while in the hospital. If it works, it may improve symptoms and recovery during this acute phase.
Oklahoma City, OklahomaAges 18–80 - NCT05433220Recruiting
Messaging to doctors about treating heart failure
This study tests whether sending guidance messages to your cardiologist improves how heart failure care is provided. It may help patients get the right medication plan, if they are not already on the strongest versions of the standard treatments.
Falls Church, VirginiaAges 18 years+ - NCT05323487RecruitingPhase 1
Study why water pills (diuretics) stop working in heart failure
This Phase 1 study looks at why “water pills” sometimes stop relieving fluid overload in people with heart failure. It may help researchers understand the causes of diuretic resistance and improve future treatment for fluid management.
New Haven, ConnecticutAges 18 years+ - NCT05753059RecruitingPhase 1
Study why some water pills stop working in heart failure
This Phase 1 study looks at why “water pills” (diuretics) like bumetanide may not remove fluid as expected in people with heart failure. The results may help clinicians improve treatment strategies for fluid control in the future.
New Haven, ConnecticutAges 18 years+ - NCT05960968Recruiting
Hospital heart failure registry for adults in Santiago
This is a registry study that collects information from adults hospitalized for heart failure in Santiago. It aims to better understand heart failure in real-world patients, including differences by sex, by tracking what happens during the hospital stay.
Santiago, Santiago MetropolitanAges 18 years+ - NCT06161649Recruiting
Mobile education for heart failure patients
This trial tests a mobile education system designed to help people with heart failure learn more about their condition, build confidence in managing it, and improve their quality of life. You'll use a smartphone app to access helpful information and support.
KeelungAges 20 years+ - NCT06209359RecruitingPhase 1
Testing a second diuretic for heart failure patients
This trial tests whether adding a second type of diuretic (water pill) can help people with heart failure who don't respond well to their current diuretic. It aims to find better ways to manage fluid buildup.
New Haven, ConnecticutAges 18 years+ - NCT06285760Recruiting
Acetazolamide for fluid removal in acute heart failure
This study tests whether adding acetazolamide (a different type of water pill) to your current treatment helps remove extra fluid from your body more effectively when you are in the hospital for heart failure.
MadridAges Any age - NCT06324682Recruiting
Comparing heart pacemaker types for better treatment
This trial looks at different ways to pace the heart (like left, right, or both sides) to see which works best for people who need a pacemaker. If you have a heart condition requiring a pacemaker, this study may help find the safest and most effective option for you.
Ferrara, FEAges 18 years+ - NCT06495892RecruitingPhase 4
PVP-guided fluid removal for heart failure patients
This study tests a new way to guide fluid removal (decongestive therapy) in people hospitalized for heart failure. It aims to help doctors safely reduce fluid buildup, no matter what type of heart failure you have.
AnkaraAges 18–99 - NCT06560047Recruiting
Early catheter ablation for atrial fibrillation with heart failure
This trial tests whether early catheter ablation (a procedure to fix irregular heartbeats) helps people who have both heart failure and atrial fibrillation. It looks at how this treatment affects your heart function and quality of life.
AalborgAges 18–80
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Common questions
- Are there clinical trials for heart failure?
- Yes. Clin2 currently lists 982 recruiting heart failure studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a heart failure trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a heart failure trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.