Clinical trials
Heart failure clinical trials
A condition where the heart can’t pump blood as well as it should. We’re tracking 949 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07385417Recruiting
Early AF treatment for heart failure with preserved pumping function
This study tests using a new electrical pulse treatment for atrial fibrillation (AF) early on, in people who also have a type of heart failure where the heart pumps normally but is stiff. The goal is to see if this treatment helps manage both conditions better.
Frankfurt am MainAges 18–80 - NCT07372196Recruiting
Left bundle branch pacing after myectomy for hypertrophic cardiomyopathy
This trial is testing a new way to pace the heart (left bundle branch pacing) for people with hypertrophic cardiomyopathy who still have a dangerous heart rhythm problem after myectomy surgery. It aims to see if this pacing can reduce the risk of sudden cardiac death.
Novosibirsk, Novosibirsk OblastAges 18–75 - NCT07375251Enrolling by invitation
Heart app study for stable heart failure patients
This study tests if using a smartphone app can help monitor stable heart failure at home. If you have stable heart failure and can use a smartphone, you may be able to join.
Sassari, SSAges 18 years+ - NCT07360158Recruiting
Studying a new implantable heart device (ICD) for heart patients
This study is testing a new type of implantable cardioverter-defibrillator (ICD) or cardiac resynchronization therapy defibrillator (CRT-D) called the CorSky Family. The goal is to see how well it works for people who need a device to help their heart pump properly and prevent dangerous rhythms.
Graz, StyriaAges 18–99 - NCT06162247Recruiting
Registry study for heart patients in intensive care
This study tracks patients with sudden heart problems admitted to a special heart intensive care unit. It helps doctors learn more about these conditions to improve future care.
NaplesAges 18 years+ - NCT06811519Recruiting
AI predicts heart function from ultrasound and body scans
This study uses artificial intelligence to predict how well your heart is pumping by looking at your heart ultrasound results and body composition (like body fat and muscle). The goal is to see if adding body composition data makes the AI predictions more accurate.
Yongin, Gyeonggi-doAges 20 years+ - NCT07344480Recruiting
Study on heart disease in children with RASopathy
This study looks at medical records of children with a genetic condition called RASopathy who developed thickened heart muscle and needed hospital care for heart failure in their first six months of life. The goal is to understand how the heart condition progresses over time.
MünchenAges Any age - NCT07347925Recruiting
Study of heart failure medicine before hospital
This trial tests if a specific heart failure pill, started before hospital care, helps improve short-term outcomes in people with weak heart muscles. It is for patients with a low pumping ability of the heart.
Al MansurahAges 18 years+ - NCT07336316Enrolling by invitation
Heart MRI study for early heart failure with preserved pump function
This trial uses advanced MRI scans to study early signs of heart failure in people whose heart pumps normally but who have risk factors like diabetes, high blood pressure, or obesity. It aims to improve detection and understanding of this condition.
Ages Any age - NCT06862700Recruiting
Less vasopressors for heart shock on ECMO
This trial is studying whether using less of the medicines that raise blood pressure (vasopressors) can help people with severe heart failure who are on a heart-lung machine (ECMO) survive. It may answer if a gentler approach is safer.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07324772Recruiting
Exercise program to improve symptoms in atrial fibrillation and heart failure
This study tests if starting a supervised exercise program can help older adults with both atrial fibrillation and a type of heart failure called HFpEF feel better and have a better quality of life. You'll be asked to join exercise sessions and have regular check-ins to see how you're doing.
Chicago, IllinoisAges 60–99 - NCT05828719Recruiting
Compare heart stent treatment vs medicines for weak heart function
This study looks at whether opening blocked heart arteries with a stent (a PCI procedure) works better than staying on heart medicines for people with weakened pumping function and certain types of heart failure. It may help patients by testing which approach best improves outcomes over time.
SeoulAges 19 years+ - NCT07304817RecruitingPhase 2
Comparing two heart and kidney medicines in heart failure
This study tests if a new medicine (vicadrostat) works differently than an older one (spironolactone) in people with heart failure or heart disease and reduced kidney function. It aims to understand how they affect proteins in the blood and kidney blood flow.
Groningen, Provincie GroningenAges 18 years+ - NCT07293923Recruiting
Magenta Elevate™ study for cardiogenic shock
This trial tests a new heart pump called the Magenta Elevate™ to help people whose heart suddenly stops pumping enough blood (cardiogenic shock). It aims to improve blood flow and reduce strain on the heart.
TbilisiAges 40–89 - NCT07283666Enrolling by invitation
Heart care quality program for AFib and heart failure
This trial aims to improve care for people with atrial fibrillation (a type of irregular heartbeat) or heart failure with reduced pumping strength. It focuses on making sure you get the right treatments based on your health history and recent visits to a heart doctor.
New York, New YorkAges 18–90 - NCT07269366Recruiting
Surgery vs stents for heart disease with weak heart pump
This trial compares two ways to restore blood flow to the heart—bypass surgery (CABG) or stents (PCI)—in people whose heart pumps weakly (LVEF 40% or less). It aims to find which method works better for chest pain or recent heart issues.
GroningenAges 18 years+ - NCT07270536Recruiting
Pacing and heart pressure in HFpEF exercise
This study tests whether a special pacing setting during exercise can help improve heart filling pressures in people with heart failure with preserved ejection fraction (HFpEF) who already have a DDD pacemaker. If you have HFpEF and a pacemaker, you may help researchers find better ways to manage your condition during activity.
HasseltAges 18 years+ - NCT07273838RecruitingPhase 2
SGLT2 inhibitor for acute heart and kidney failure
This study tests whether a medicine called an SGLT2 inhibitor (which lowers blood sugar and helps the kidneys) can improve outcomes for people with acute heart failure and kidney problems. Participation involves taking the study drug or a placebo for a short time.
New Haven, ConnecticutAges 18–85 - NCT07276139Recruiting
Heart device experience and outcomes study
This study collects information from people who have a heart device (like a pacemaker) to learn how these devices work in real life and how they affect patients. By joining, you help doctors improve care for future patients.
Canberra, Australian Capital TerritoryAges 18 years+ - NCT06378632Recruiting
Heart failure monitoring app study
This study tests a smartphone app that listens to your voice to detect early signs of heart failure worsening. It aims to help you avoid hospital stays by catching problems sooner.
Fairhope, AlabamaAges 22 years+ - NCT07252856Recruiting
Digital support for heart rehab (phase III)
This trial tests a digital tool to help people with heart disease continue their cardiac rehabilitation at home during the maintenance phase. It's for people who have already completed the earlier rehab phase and are ready for long-term support.
LeuvenAges 18 years+ - NCT07251361Enrolling by invitation
Exercise program for heart failure with preserved ejection fraction
This study tests whether a special exercise program that combines different types of training (like aerobic, strength, and balance) can improve heart and muscle function, daily abilities, and quality of life in people with heart failure with preserved ejection fraction (HFpEF). You may benefit if your heart failure is stable and you are able to exercise safely.
Pamplona, NavarreAges 18 years+ - NCT06065124Recruiting
Study on weight loss surgery for heart failure with irregular heartbeat
This trial tests if weight loss surgery can help people with heart failure and atrial fibrillation (an irregular heartbeat) improve their heart condition. You may join if you are between 45 and 70, have a BMI of 32 to 40, and have mild to moderate heart failure with preserved pumping function.
Arnhem, GelderlandAges 45–70 - NCT07245069RecruitingPhase 2
Can dapagliflozin protect the heart during breast cancer chemo?
This trial tests if the drug dapagliflozin can prevent heart damage caused by anthracycline chemotherapy in breast cancer patients. It aims to see if taking the drug during chemo helps keep your heart healthy.
LjubljanaAges 18 years+
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Common questions
- Are there clinical trials for heart failure?
- Yes. Clin2 currently lists 949 recruiting heart failure studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a heart failure trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a heart failure trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.