Clinical trials
Heart Valve Diseases clinical trials
Below are recruiting heart valve diseases clinical trials, each written for real people, not researchers. We’re tracking 224 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05930899Recruiting
Study tissue and blood samples from heart disease patients
This study builds a biobank, meaning it collects and stores your health information, blood, and possibly heart-related samples to help researchers learn why heart conditions happen. You might join if you have certain heart diagnoses and are having cardiac surgery for a problem other than an aortic valve issue.
Montreal, QuebecAges 19 years+ - NCT02966665RecruitingPhase 1
Testing blood vessel function in people of different health conditions
This early study measures how well your blood vessels work using tests that may include MRI. It compares healthy people with people who have conditions like COPD, pulmonary arterial hypertension, heart failure, or high blood pressure, to better understand “vascular function” in health and disease.
Salt Lake City, UtahAges 18 years+ - NCT07456280Recruiting
Early discharge after TAVI using heart monitoring
This study tests if patients who have mild heart electrical changes after TAVI can be sent home early with a portable heart monitor instead of staying in the hospital. It aims to see if this approach is safe and effective.
BarcelonaAges 18 years+ - NCT05825898Enrolling by invitation
Treatment outcomes for severe leaking tricuspid valve
This study looks at what happens to adults with moderate-to-severe or severe tricuspid valve “leaking” after different treatment types, such as catheter-based or surgery. It may help doctors understand which approach works best for people with severe valve leakage and symptoms.
Rochester, MinnesotaAges 18 years+ - NCT05261204Enrolling by invitation
TAVR vs surgery for narrowed aortic valve
This trial compares a less invasive valve procedure called TAVR with standard open-heart surgery to replace a narrowed aortic valve. It studies which approach works best for people who are considered higher risk for surgery.
Saint-DenisAges 18–90 - NCT06414265Recruiting
Testing a new valve for severe mitral regurgitation
This trial tests a new device called the SATURN system, which places a new mitral valve without open-heart surgery. It is for people aged 65 and older with severe mitral regurgitation who are at high risk for surgery.
TbilisiAges 65 years+ - NCT06272578Recruiting
Heart and kidney health study for chronic disease patients
This study checks how heart and kidney health are related in people with kidney disease, diabetes, high blood pressure, or high cholesterol. It is a single visit with tests to see if certain heart problems are common in these conditions.
Wedding, State of BerlinAges 18 years+ - NCT06507657RecruitingEarly Phase 1
Empagliflozin for heart health in older adults
This study tests whether a medication called empagliflozin (a diabetes drug) can improve heart function in older adults with high blood pressure and obesity who are at risk for heart failure but do not have it yet. You would take the pill daily and have heart ultrasounds to check your heart's health.
Minneapolis, MinnesotaAges 60 years+ - NCT06706635Recruiting
Better info for aortic stenosis patients before TAVI
This trial tests whether giving extra information before heart valve replacement (TAVI) helps patients feel more informed and improves their reported outcomes. If you have severe aortic stenosis and are planning to get a TAVI, this study may be for you.
Bad OeynhausenAges 18 years+ - NCT07601867Recruiting
Dapagliflozin to improve heart function after bypass surgery
This trial tests whether a diabetes medication called dapagliflozin can help improve how well the right side of your heart works after off-pump coronary artery bypass grafting surgery (a way to reroute blood around blocked heart arteries). The goal is to see if this drug reduces strain on your heart during recovery.
Pyatigorsk, Stavropol KrayAges 18 years+ - NCT07480915Recruiting
Heart failure risk after bypass surgery
This study looks at how to predict major heart problems in people with heart failure who are scheduled for bypass surgery (CABG). It aims to improve risk assessment before the procedure.
Tomsk, Tomsk OblastAges Any age - NCT04634240Recruiting
Staged heart bypass plus TAVR versus TAVR alone
This study compares doing a staged coronary bypass (revascularization) along with a valve procedure (TAVR) versus doing TAVR and medical treatment alone. It aims to see which approach better helps people with both aortic valve narrowing and coronary artery disease.
Huntsville, AlabamaAges Any age - NCT05739253Recruiting
Study how the aorta changes after a valve procedure
This trial looks at how the ascending aorta (the main artery near the heart) changes over time after transcatheter aortic valve replacement. It may help doctors predict who is at risk of aorta enlargement after this less-invasive valve procedure.
Beijing, Beijing MunicipalityAges Any age - NCT07217392Recruiting
Study on pacing the left bundle branch area of the heart
This study tests a new way to place a pacemaker lead in the left bundle branch area of the heart. It may help people who need a pacemaker to see if this approach is safe and works well.
Rio de Janeiro, Rio de JaneiroAges 18 years+ - NCT07055919Recruiting
Assist system for mitral valve clip procedure
This study is testing a new assist system to help doctors perform a minimally invasive procedure (MitraClip) that clips the leaky mitral valve without open-heart surgery. It is for people with severe mitral regurgitation who cannot safely have surgery or choose not to.
Xiamen, FujianAges 18 years+ - NCT06743568Recruiting
Comparing new valves for tight aortic valve in enlarged aorta
This trial tests two types of replacement heart valves (self-expanding and balloon-expanding) in people who have severe aortic stenosis (tight heart valve) and an enlarged aorta (the main blood vessel from the heart). The goal is to see which valve type works better for these patients.
Beijing, Beijing MunicipalityAges 65 years+ - NCT07354841Recruiting
Testing safety of heart-lung machine tubes
This study tests two types of tubes used during heart surgery to connect you to a heart-lung machine. It aims to see if they work safely and effectively.
Bari, BAAges 18 years+ - NCT06607471Recruiting
Study on non-ischemic heart muscle diseases
This study looks at different types of heart muscle diseases that are not caused by blocked arteries (non-ischemic cardiomyopathies). It aims to better understand how to diagnose, predict outcomes, and treat these conditions by gathering information from many patients over time.
Milan, MilanoAges 18 years+ - NCT04162444Recruiting
Aortic valve reconstruction study for children
This trial studies a surgery approach to help fix a narrowed or leaking aortic valve in children. It aims to see how well the reconstructed valve works and how it affects the child’s heart function over time.
MoscowAges 4 weeks–12 years - NCT06349174Recruiting
Lung valve treatment for severe COPD
This study tests whether placing tiny valves in the airways can help people with severe COPD breathe easier. It is for people who still have trouble breathing despite quitting smoking and completing pulmonary rehab.
Beijing, Beijing MunicipalityAges 40–85 - NCT06689839Recruiting
Testing a new filter to prevent stroke during heart valve replacement
This trial tests a new filter device designed to catch debris that might travel to the brain during a minimally invasive aortic valve replacement (TAVR). The goal is to see if it can help reduce the risk of stroke.
Naples, FloridaAges 50 years+ - NCT03549559Recruiting
Heart imaging study in healthy people and specific conditions
This study uses heart imaging to look at changes in the heart muscle. It includes healthy volunteers and people with diabetes or aortic stenosis, to understand differences seen on scans.
Boston, MassachusettsAges 18–85 - NCT02537769Recruiting
Surgery to fix a leaky tricuspid valve in LVAD patients
This study looks at whether fixing a mildly leaky tricuspid valve during LVAD surgery improves outcomes for people with advanced heart failure. It’s mainly aimed at patients who are already scheduled to receive an implantable LVAD.
Seattle, WashingtonAges 18 years+ - NCT07298122Recruiting
Heart imaging for hidden clots in ESUS stroke with left ventricular disease
This study uses advanced heart scans (MRI or CT) to look for blood clots in the heart of people who had a stroke with an unclear cause, specifically if they also have a mild heart condition affecting the left ventricle. The goal is to find hidden clots that might be causing strokes.
Milan, LombardyAges 18 years+
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Common questions
- Are there clinical trials for heart valve diseases?
- Yes. Clin2 currently lists 224 recruiting heart valve diseases studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a heart valve diseases trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a heart valve diseases trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.