Clinical trials
Heart Valve Diseases clinical trials
Below are recruiting heart valve diseases clinical trials, each written for real people, not researchers. We’re tracking 228 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06952374Recruiting
Shockwave balloon for severe mitral valve calcium
This trial tests a special balloon (Shockwave) to treat severe calcium buildup in the mitral valve. It may help people with tight valve opening who cannot have standard surgery.
Shatin, New TerritoriesAges 18 years+ - NCT04709900Recruiting
Tests for stable chest pain using heart scans and pressure measurements
This trial studies how well different heart tests (imaging the blood flow and measuring blood pressure in the heart) work for people with stable chest pain. It may help guide safer, more accurate evaluation when you are not having a heart attack.
CopenhagenAges Any age - NCT05770349Recruiting
Heart failure patients having bypass surgery are studied
This study looks at tiny structures inside heart muscle cells (especially “power stations” in the cells) in people with certain types of heart failure who are getting coronary bypass surgery. It may help researchers better understand what changes happen in the heart and how this could guide future care.
TomskAges 18 years+ - NCT06507449Enrolling by invitation
Treating Heavily Calcified Heart Blockages to Improve Microcirculation
This study is testing a technique to treat heavily calcified (hard) blockages in heart arteries. The goal is to see if a special way of preparing the blockage before placing a stent helps improve blood flow to the tiny blood vessels in the heart muscle.
KatowiceAges 18 years+ - NCT07620925Recruiting
Aortic Valve Calcium Score Study Using Heart Ultrasound
This study develops and tests a new way to diagnose severe aortic stenosis (narrowing of the aortic valve) by measuring calcium buildup on the valve using heart ultrasound. If you're already getting both an ultrasound and a CT scan of your heart, this study compares how well the ultrasound method can identify severe stenosis.
BolognaAges 18 years+ - NCT06705023RecruitingPhase 2
Fat-derived cell therapy for heart failure
This study tests whether taking a small amount of your own belly fat (through liposuction), processing it, and injecting the cells back into your heart can improve heart function in people with chronic heart failure due to blocked arteries. The trial is for patients whose heart pumps weakly (ejection fraction of 40% or less) and who are already on standard medications.
AstanaAges 21–80 - NCT02817360RecruitingPhase 4
Preventing heart events in people with type 2 diabetes
This trial tests a heart-focused prevention approach to lower the risk of cardiac (heart) events in adults with type 2 diabetes. It may help by targeting early stress on the heart measured with a specific blood test.
Mödling, Lower AustriaAges 18 years+ - NCT05747404Recruiting
3D heart ultrasound study for certain right-heart problems
This study uses a special 3D heart ultrasound to measure how well the tricuspid valve and right side of the heart are working. It may help improve how these conditions are evaluated and followed over time.
MilanAges 18 years+ - NCT07794527Recruiting
Nerve blocks to improve recovery after heart bypass surgery
This study tests whether giving multiple nerve blocks (numbing injections near nerves) during off-pump heart bypass surgery can improve your recovery and pain control. It aims to see if these blocks help you feel better and recover faster after surgery.
CairoAges 18–65 - NCT06775639Recruiting
Can we skip a heart artery test before surgery?
This study looks at whether people with adult congenital heart disease can skip a pre-surgery artery test (coronary angiography) if they already had a CT scan. If you qualify, you might help doctors find safer, simpler ways to prepare for heart surgery.
BolognaAges 18 years+ - NCT04484675RecruitingPhase 4
Milrinone during heart surgery for severe pulmonary hypertension
This trial tests whether giving milrinone through a vein and inhaled during mitral valve surgery helps people with severe pulmonary hypertension. The goal is to improve heart and lung blood-flow stability around the time of surgery.
Zagazig, Sharqia ProvinceAges 18 years+ - NCT07174206Recruiting
Smartwatch monitoring for heart patients
This trial tests a smartwatch tool to track heart rhythm and detect problems in people with heart disease. It may help find irregular heartbeats early during routine checkups.
São Paulo, São PauloAges 22 years+ - NCT07095829Recruiting
Predicting circulation after birth for severe pulmonary valve blockage
This study looks at babies with a severe heart defect where the pulmonary valve is blocked and the wall between the heart's lower chambers is intact. It aims to predict how well blood will flow after birth using ultrasound images taken during pregnancy.
MadridAges 4 months–6 months - NCT06490250Recruiting
Breathing vs. movement exercises for hypertrophic cardiomyopathy
This study compares two types of gentle exercises—breathing muscle training and a traditional Chinese movement practice called Baduanjin—to see which helps people with hypertrophic cardiomyopathy feel better and improve their daily life. If you have a thickened heart muscle but are stable and have mild symptoms, you may be able to join.
IstanbulAges 18 years+ - NCT06891456Recruiting
Pulsed field ablation for ventricular tachycardia after heart attack
This trial tests a new type of energy (pulsed field ablation) to treat a fast heart rhythm called ventricular tachycardia that happens after a heart attack. The goal is to stop the dangerous rhythm without damaging nearby healthy tissue.
Cleveland, OhioAges 18 years+ - NCT06352671Recruiting
Long-Term Outcomes of a Standardized Ross Procedure
This study follows patients who are having a Ross procedure (a type of heart valve surgery) at select hospitals. Researchers will track their health outcomes over a long period to understand how well the surgery works.
Plano, TexasAges 18–90 - NCT06286358Recruiting
Heart and aorta imaging study for valve disease
This study uses a special recording device to see if heart and aorta problems can be detected earlier. It may help people with aortic valve disease or enlarged aorta decide on treatment.
BrusselsAges 18 years+ - NCT06066970Recruiting
Studying heart markers after valve surgery
This trial uses a special MRI and blood tests to see how heart muscle is affected after aortic or mitral valve surgery. It may help doctors better understand and monitor heart recovery.
Freiburg im Breisgau, Baden-WurttembergAges 18 years+ - NCT06145035RecruitingPhase 2
Stem cells from cord blood for heart failure
This trial tests whether stem cells from donated umbilical cord blood can improve heart function in people with heart failure caused by blocked arteries. You'll receive one or more infusions of these cells through a vein.
Miami, FloridaAges 21–85 - NCT06077422Enrolling by invitationPhase 2/Phase 3
Comparing two pain blocks for heart surgery recovery
This trial compares two types of pain blocks (Exparel vs. Marcaine) given during heart surgery to see which one provides better pain relief. If you are scheduled for a heart surgery through a small or full chest incision, you may be able to join.
New Brunswick, New JerseyAges 18 years+ - NCT05172960Recruiting
Study of a new heart valve for severe aortic stenosis
This trial tests a new version of a heart valve (SAPIEN X4) placed without open-heart surgery. It's for people with severe aortic stenosis who have symptoms like shortness of breath or chest pain.
La Jolla, CaliforniaAges Any age - NCT00243776Recruiting
Study of heart tissue changes during certain heart surgeries
This study collects and analyzes small samples of heart tissue during specific heart operations in babies or children. The goal is to better understand how the heart develops after birth, which could improve future care.
Atlanta, GeorgiaAges Up to 20 years - NCT07434193Recruiting
Pacing study after aortic valve replacement
This trial tests if special pacing of the heart's lower chambers (called cardiac resynchronization therapy, or CRT) can help people who develop a new electrical delay in the heart after having a transcatheter aortic valve replacement (TAVI). The study compares two types of pacing to see which works better for recovery.
BudapestAges 18 years+ - NCT07370688RecruitingPhase 4
Iron infusion after TAVI for older adults
This trial tests whether giving iron infusions after a TAVI procedure can help patients with iron deficiency feel better and improve their quality of life. It is for older adults who have low iron levels and have already had a successful valve replacement.
Rotterdam, South HollandAges 65 years+
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Common questions
- Are there clinical trials for heart valve diseases?
- Yes. Clin2 currently lists 228 recruiting heart valve diseases studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a heart valve diseases trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a heart valve diseases trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.