Clinical trials
His Bundle Pacing clinical trials
Below are recruiting his bundle pacing clinical trials, each written for real people, not researchers. We’re tracking 39 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05815745Recruiting
Compare two heart pacing strategies for slow heart rhythm
This study compares two types of heart pacing—one that mainly targets the heart’s lower chambers versus one that targets the right side—to see which leads to better outcomes for people needing a pacemaker. It may help improve treatment for certain slow heart rhythm problems that require pacing.
DublinAges 18 years+ - NCT05585411Recruiting
Pacemaker type test to reduce heart worsening and death risk
This study compares two pacemaker pacing strategies—left-sided “bundle branch area” pacing versus right-sided ventricular pacing. It aims to see which approach better prevents heart failure getting worse and reduces abnormal timing between heart chambers over time.
Bucheon-siAges 19 years+ - NCT07206602Recruiting
AI-guided left bundle branch pacing
This trial tests a new way to place a pacemaker lead in the heart's left bundle branch area, guided by artificial intelligence. It aims to improve heart function in people with heart failure who need pacing.
Rochester, MinnesotaAges 18 years+ - NCT05491655Recruiting
Testing a new pacing approach in some heart failure patients
This study looks at whether a high-intensity “His bundle” heart pacing method can help people with heart failure who have a specific heart rhythm pattern on ECG. It likely aims to improve heart pumping and symptoms in people who are otherwise a good match for an ICD and meet other criteria.
Acquaviva delle Fonti, BariAges 18–90 - NCT04416958Recruiting
Pacemaker or defibrillator pacing strategy to reduce heart timing issues
This study looks at a pacing approach for people with a pacemaker or ICD (defibrillator) to help prevent the heartbeats from becoming out of sync. It may be useful if your implant team is trying to reduce pacing-related “timing” problems in the heart.
Fürth, BavariaAges 18 years+ - NCT05015660Recruiting
Testing left bundle pacing versus usual right pacing
This study compares a newer heart pacing method (left bundle branch pacing) to the standard method (right ventricular pacing) in people who need most of their heartbeats paced. It may help improve how well the heart pumps over time.
Montreal, QuebecAges 18 years+ - NCT06620705Recruiting
Pacing options for AF with low heart function
This trial compares two types of pacing for people with permanent atrial fibrillation (AF) and a weak heart pump (ejection fraction less than 50%). It tests whether pacing the left bundle branch area works as well as or better than standard biventricular pacing to improve heart function.
Aarhus N, Aarhus NAges 18 years+ - NCT07250529Recruiting
Comparing two pacemaker pacing methods for heart block
This study compares two types of pacemaker pacing methods in people with heart block and normal heart pumping function. It looks at how often short bursts of fast heart rhythm occur in the upper heart chambers, which may help improve long-term heart health.
PátraiAges 18 years+ - NCT07372196Recruiting
Left bundle branch pacing after myectomy for hypertrophic cardiomyopathy
This trial is testing a new way to pace the heart (left bundle branch pacing) for people with hypertrophic cardiomyopathy who still have a dangerous heart rhythm problem after myectomy surgery. It aims to see if this pacing can reduce the risk of sudden cardiac death.
Novosibirsk, Novosibirsk OblastAges 18–75 - NCT05265520Recruiting
Pacing strategy study for certain heart failure patients
This trial tests a pacing approach designed to improve how the heart beats in some people with heart failure and a specific heart rhythm pattern on ECG. If you already need a device (CRT-D) based on your results, the study may help see whether this pacing correction improves outcomes.
Phoenix, ArizonaAges 18 years+ - NCT07360067Recruiting
Comparing two types of heart pacing for sick sinus syndrome
This study compares two different ways of placing a pacemaker lead to see which one better helps heart function and reduces future heart problems in people with sick sinus syndrome.
Seoul, SeoulAges 19 years+ - NCT07217392Recruiting
Study on pacing the left bundle branch area of the heart
This study tests a new way to place a pacemaker lead in the left bundle branch area of the heart. It may help people who need a pacemaker to see if this approach is safe and works well.
Rio de Janeiro, Rio de JaneiroAges 18 years+ - NCT05769036Recruiting
Biventricular vs left bundle pacing for heart failure outcomes
This trial compares two types of heart pacing to see which improves outcomes for people with heart failure. It may help those who need pacing to better coordinate heartbeats and relieve symptoms.
TomskAges 18–80 - NCT07057544Recruiting
New ECG method to predict CRT benefit in heart failure
This trial tests a new way to use an ECG (electrical heart recording) to predict who will benefit from a special pacemaker called cardiac resynchronization therapy (CRT). It is for people with heart failure and a specific heart rhythm problem.
Prague, Česká RepublikaAges 18 years+ - NCT06707662Recruiting
Pacing methods to protect heart function
This trial tests two pacing approaches to see which one better prevents weakening of the heart's main pumping chamber. It's for people who need a pacemaker for a slow heart rhythm and are expected to rely on it heavily.
BarcelonaAges 18 years+ - NCT06152406Recruiting
Ablate and Pace HIS for atrial fibrillation and heart failure
This study tests a new approach called 'Ablate and Pace HIS' for people with atrial fibrillation and heart failure who haven't improved with other treatments. It combines a heart ablation procedure with a special type of pacing to help your heart pump more efficiently and reduce symptoms.
Leicester, LeicestershireAges 18–100 - NCT07254013Recruiting
LBBAP Pacemaker Monitoring with Portable ECG
This study is testing a portable heart monitoring device to help doctors check how well a special pacemaker (LBBAP) is working. It may help people who need a new or upgraded pacemaker or heart device.
Besançon, FranceAges 18 years+ - NCT06699342Recruiting
Pacing and heart ablation for atrial fibrillation
This trial tests a combination of heart pacing and a specialized ablation procedure in older adults with permanent atrial fibrillation that hasn't improved with other treatments. It aims to improve symptoms and reduce hospital stays related to heart failure.
Seoul, Jongno-guAges 65 years+ - NCT07791407Recruiting
Heart imaging to guide defibrillator placement in heart failure
This study uses an MRI scan of the heart to better identify which people with heart failure need a defibrillator along with a special pacemaker (cardiac resynchronization therapy). The scan may help doctors decide if the device could improve your heart's pumping and reduce risks.
Madurai, Tamil NaduAges 18 years+ - NCT07430553Recruiting
Comparing pacemakers for better heart function in heart failure
This trial compares three types of advanced pacemakers (cardiac resynchronization therapy devices) to see which works best for improving heart function and reducing abnormal heart rhythms in people with heart failure.
London, Greater LondonAges 18 years+ - NCT05760924Recruiting
Testing a new heart pacing method for CRT nonresponders
This trial tests whether a different pacing approach called left bundle branch pacing can improve outcomes and heart structure changes in people who did not improve with standard biventricular CRT. It may help some patients with ongoing heart failure symptoms and weak heart pumping.
TomskAges 18–80 - NCT05884359Recruiting
Mapping how a pacemaker is placed in the heart
This trial focuses on testing a new way to map (map out) where a specific pacemaker lead is placed in the heart for people getting left bundle branch area pacing. It may help doctors improve how the pacemaker is implanted and confirm the lead is in the right spot.
Boston, MassachusettsAges 18–88 - NCT07110922Recruiting
Pacing the heart's natural electrical highway: Bachmann bundle pacing study
This trial tests a special way to place a pacemaker lead that may improve heart function by pacing the Bachmann bundle, a key electrical pathway between the upper heart chambers. It is designed for people who already need a pacemaker or an ICD with an atrial lead.
Wilkes-Barre, PennsylvaniaAges 18 years+ - NCT03008291Recruiting
Heart pacemaker study for slow heartbeats and heart failure
This trial tests how pacing from a specific part of the heart (a “bundle” pacing approach) can affect people with heart failure and/or slow heart rhythms. It may help certain patients whose heart rhythm is too slow or who need a pacemaker and related devices.
Rochester, MinnesotaAges 18 years+
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Common questions
- Are there clinical trials for his bundle pacing?
- Yes. Clin2 currently lists 39 recruiting his bundle pacing studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a his bundle pacing trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a his bundle pacing trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.