Clinical trials
Left Bundle Branch Pacing clinical trials
Below are recruiting left bundle branch pacing clinical trials, each written for real people, not researchers. We’re tracking 37 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06689111Recruiting
Heart resynchronization method study for patients with LBBB and heart failure
This study compares two ways to resynchronize the heart's pumping in people with heart failure and a specific heart block (LBBB). It uses special ultrasound imaging to see which method works better for improving heart function.
Pátrai, GreeceAges 18–90 - NCT06061978Recruiting
Pacing after a heart procedure for rapid atrial fibrillation
This trial studies whether a special type of pacing (stimulating the heart's natural electrical system) works better than standard pacing after a procedure to control very fast heart rhythms. It's for people who already have a pacemaker and are getting a specific treatment for atrial fibrillation.
CaenAges 18 years+ - NCT06148571Recruiting
Pacing study for heart failure with low pumping strength
This trial tests a new way of pacing the heart (left bundle branch area pacing) in people with heart failure and reduced or mid-range ejection fraction. It aims to improve heart function in patients who already need a pacemaker or resynchronization therapy.
Seoul, Jongno-guAges 19 years+ - NCT07434193Recruiting
Pacing study after aortic valve replacement
This trial tests if special pacing of the heart's lower chambers (called cardiac resynchronization therapy, or CRT) can help people who develop a new electrical delay in the heart after having a transcatheter aortic valve replacement (TAVI). The study compares two types of pacing to see which works better for recovery.
BudapestAges 18 years+ - NCT07069738Recruiting
New pacemaker vs standard cardiac therapy for heart failure
This study tests a newer type of pacemaker that paces the heart's left bundle branch area, compared to the usual cardiac resynchronization therapy. It is for people with heart failure who need a combined pacemaker-defibrillator (CRT-D) and have a specific heart rhythm pattern (left bundle branch block) with reduced pumping strength.
Huntsville, AlabamaAges 18 years+ - NCT05884359Recruiting
Mapping how a pacemaker is placed in the heart
This trial focuses on testing a new way to map (map out) where a specific pacemaker lead is placed in the heart for people getting left bundle branch area pacing. It may help doctors improve how the pacemaker is implanted and confirm the lead is in the right spot.
Boston, MassachusettsAges 18–88 - NCT05815745Recruiting
Compare two heart pacing strategies for slow heart rhythm
This study compares two types of heart pacing—one that mainly targets the heart’s lower chambers versus one that targets the right side—to see which leads to better outcomes for people needing a pacemaker. It may help improve treatment for certain slow heart rhythm problems that require pacing.
DublinAges 18 years+ - NCT04293471Recruiting
Echocardiogram test to predict outcomes in CRT patients
This trial looks at how well an echocardiogram (ultrasound of the heart) can predict outcomes for people with left bundle branch block who already have cardiac resynchronisation therapy (CRT). If you qualify, your heart scans may be used to better estimate risk and guide care.
Tromsø, TromsAges 18–100 - NCT04416958Recruiting
Pacemaker or defibrillator pacing strategy to reduce heart timing issues
This study looks at a pacing approach for people with a pacemaker or ICD (defibrillator) to help prevent the heartbeats from becoming out of sync. It may be useful if your implant team is trying to reduce pacing-related “timing” problems in the heart.
Fürth, BavariaAges 18 years+ - NCT05015660Recruiting
Testing left bundle pacing versus usual right pacing
This study compares a newer heart pacing method (left bundle branch pacing) to the standard method (right ventricular pacing) in people who need most of their heartbeats paced. It may help improve how well the heart pumps over time.
Montreal, QuebecAges 18 years+ - NCT05265520Recruiting
Pacing strategy study for certain heart failure patients
This trial tests a pacing approach designed to improve how the heart beats in some people with heart failure and a specific heart rhythm pattern on ECG. If you already need a device (CRT-D) based on your results, the study may help see whether this pacing correction improves outcomes.
Phoenix, ArizonaAges 18 years+ - NCT05283603Recruiting
Registry study for people with left bundle branch block
This is an observational registry that collects health information from people who have a heart rhythm pattern called left bundle branch block. It may help doctors better understand causes, outcomes, and care needs for people with this ECG finding.
SassariAges 18 years+ - NCT05585411Recruiting
Pacemaker type test to reduce heart worsening and death risk
This study compares two pacemaker pacing strategies—left-sided “bundle branch area” pacing versus right-sided ventricular pacing. It aims to see which approach better prevents heart failure getting worse and reduces abnormal timing between heart chambers over time.
Bucheon-siAges 19 years+ - NCT05760924Recruiting
Testing a new heart pacing method for CRT nonresponders
This trial tests whether a different pacing approach called left bundle branch pacing can improve outcomes and heart structure changes in people who did not improve with standard biventricular CRT. It may help some patients with ongoing heart failure symptoms and weak heart pumping.
TomskAges 18–80 - NCT05769036Recruiting
Biventricular vs left bundle pacing for heart failure outcomes
This trial compares two types of heart pacing to see which improves outcomes for people with heart failure. It may help those who need pacing to better coordinate heartbeats and relieve symptoms.
TomskAges 18–80 - NCT06324682Recruiting
Comparing heart pacemaker types for better treatment
This trial looks at different ways to pace the heart (like left, right, or both sides) to see which works best for people who need a pacemaker. If you have a heart condition requiring a pacemaker, this study may help find the safest and most effective option for you.
Ferrara, FEAges 18 years+ - NCT06453850Recruiting
New catheter for pacemaker lead placement in the septum
This trial tests a new thin tube (catheter) used to guide a pacing wire into the wall between the heart's lower chambers, called the septum. It may be a good option if you need a first-time pacemaker or CRT-D implant and your heart's pumping function is fairly good.
CoimbraAges 18 years+ - NCT06436053Recruiting
Pacing to improve heart function study
This study tests a new way to pace the heart to see if it can improve how well the heart pumps. It uses a special Abbott pacemaker to pace a part of the heart called the left bundle branch and adjust the timing to match your natural heart rhythm.
San Donato Milanese, MIAges 18 years+ - NCT06620705Recruiting
Pacing options for AF with low heart function
This trial compares two types of pacing for people with permanent atrial fibrillation (AF) and a weak heart pump (ejection fraction less than 50%). It tests whether pacing the left bundle branch area works as well as or better than standard biventricular pacing to improve heart function.
Aarhus N, Aarhus NAges 18 years+ - NCT06699342Recruiting
Pacing and heart ablation for atrial fibrillation
This trial tests a combination of heart pacing and a specialized ablation procedure in older adults with permanent atrial fibrillation that hasn't improved with other treatments. It aims to improve symptoms and reduce hospital stays related to heart failure.
Seoul, Jongno-guAges 65 years+ - NCT06707662Recruiting
Pacing methods to protect heart function
This trial tests two pacing approaches to see which one better prevents weakening of the heart's main pumping chamber. It's for people who need a pacemaker for a slow heart rhythm and are expected to rely on it heavily.
BarcelonaAges 18 years+ - NCT06745778Recruiting
Study of heart device signals in patients with left bundle pacing
This study looks at the electrical signals recorded by a special type of pacing lead placed in the heart's left bundle branch. It aims to understand how these signals change over time in people who already have an ICD or CRT-D device.
Wenzhou, ZhejiangAges 18 years+ - NCT07057544Recruiting
New ECG method to predict CRT benefit in heart failure
This trial tests a new way to use an ECG (electrical heart recording) to predict who will benefit from a special pacemaker called cardiac resynchronization therapy (CRT). It is for people with heart failure and a specific heart rhythm problem.
Prague, Česká RepublikaAges 18 years+ - NCT07206602Recruiting
AI-guided left bundle branch pacing
This trial tests a new way to place a pacemaker lead in the heart's left bundle branch area, guided by artificial intelligence. It aims to improve heart function in people with heart failure who need pacing.
Rochester, MinnesotaAges 18 years+
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Common questions
- Are there clinical trials for left bundle branch pacing?
- Yes. Clin2 currently lists 37 recruiting left bundle branch pacing studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a left bundle branch pacing trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a left bundle branch pacing trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.