Clinical trials · California
High blood pressure clinical trials in California
We’re tracking 67 recruiting high blood pressure studies with a site in California — including Phase 1, Phase 2 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies in California
- NCT06872112RecruitingPhase 1
Artesunate for pulmonary arterial hypertension safety study
This trial tests if artesunate, a malaria drug, is safe and tolerable for people with pulmonary arterial hypertension (PAH). It may offer a new treatment option for PAH patients whose symptoms persist despite using two or more standard therapies.
Stanford, CaliforniaAges 18–60 - NCT06871462Enrolling by invitation
Texting program to help monitor blood pressure at home
This study tests a program that uses text messages to help people with high blood pressure check and manage their blood pressure at home. It may help you better control your blood pressure and reduce health risks.
San Francisco, CaliforniaAges 18 years+ - NCT06843577Recruiting
Handgrip therapy for high blood pressure
This trial tests if a simple handgrip exercise device can help lower blood pressure in people with elevated blood pressure or hypertension. You will use the device at home and have regular check-ups to see how well it works.
West Hills, CaliforniaAges 22 years+ - NCT05530512Recruiting
Acupuncture for mild to moderate high blood pressure
This study tests whether acupuncture can help lower blood pressure in people with mild to moderate hypertension. You may be asked to join because you meet age and blood-pressure ranges and have a normal heart screening ECG.
Irvine, CaliforniaAges 45–75 - NCT05479461Recruiting
Phone-based blood pressure care vs usual care
This trial tests whether a technology-enabled program (using a smartphone) helps lower blood pressure better than standard care. It may help you manage high blood pressure with guided treatment changes.
Palo Alto, CaliforniaAges 30–90 - NCT06576544Enrolling by invitation
Wearables to Track Postpartum Blood Pressure
This study uses wearable devices to track your blood pressure after childbirth. The goal is to learn when blood pressure problems occur and help create better monitoring guidelines so you and future parents can get the right care at the right time.
La Jolla, CaliforniaAges 18–50 - NCT06559891Recruiting
Ultrasound treatment for high blood pressure
This trial tests an ultrasound device that targets nerves around the kidney to lower blood pressure. It may help people whose blood pressure is not well controlled with medication.
Los Angeles, CaliforniaAges 22–75 - NCT06526858Recruiting
Laparoscopic kidney nerve treatment for resistant hypertension
This study tests a new treatment called HyperQure RDN, a laparoscopic (keyhole) surgery that targets nerves near the kidneys to lower blood pressure in people with resistant hypertension. If you have tried multiple medications but your blood pressure is still high, this procedure might offer an alternative approach.
Stanford, CaliforniaAges 22–80 - NCT06343298RecruitingPhase 2
Study of manp for hard-to-control high blood pressure
This study tests a new investigational drug called MANP to see if it can lower blood pressure in people whose blood pressure stays high even when they are already taking several medications. If it works, this drug might offer a new option for people with difficult-to-control hypertension.
Lake Forest, CaliforniaAges 18–80 - NCT05551104RecruitingPhase 3
Best blood pressure medicine after pregnancy
This study compares two common blood pressure medicines (nifedipine and labetalol) to see which is safest and works best for high blood pressure after childbirth. If you have postpartum hypertension, the trial may offer close monitoring and help doctors choose the safest option for you.
Loma Linda, CaliforniaAges 18 years+ - NCT05587712RecruitingPhase 2
Sotatercept trial for children with pulmonary arterial hypertension
This Phase 2 trial tests sotatercept, a medicine that targets the blood-vessel changes in pulmonary arterial hypertension (PAH), in children. It may help improve how well the heart and lungs work by changing the underlying disease process.
Los Angeles, CaliforniaAges 1–17 - NCT04278404Recruiting
Drug safety study for children already on certain medicines
This study measures how certain medicines move through the body and checks their safety in children. It may help doctors better understand dosing and side effects in kids who are already receiving these treatments, or in some kids who recently tested positive for COVID-19.
Los Angeles, CaliforniaAges birth–20 years - NCT04194632Recruiting
Right heart pacing study for pulmonary hypertension
This study tests whether a temporary pacemaker placed in the right heart chamber can improve heart function in people with pulmonary arterial hypertension. It aims to see if pacing can help the right heart pump more efficiently, potentially reducing symptoms.
San Francisco, CaliforniaAges 18–75 - NCT01571700Enrolling by invitation
Study breathing-heart timing differences in pulmonary hypertension
This study looks at timing mismatches (“dysynchrony”) in the heart and lungs in people with pulmonary hypertension. It may help researchers understand what causes symptoms and how the timing affects heart function.
Stanford, CaliforniaAges 5 years+ - NCT06297291Recruiting
Blood pressure study after kidney nerve treatment
This study looks at how well a procedure that uses sound waves to calm kidney nerves (renal denervation) lowers blood pressure over time. It may help people whose blood pressure stays high despite taking medication.
Long Beach, CaliforniaAges 18 years+ - NCT04669548Recruiting
Accuryn monitoring study for people having heart surgery
This registry collects information from patients who are monitored with the Accuryn system during heart surgery and their ICU stay. It helps researchers learn from the system’s signals to better understand patient care around cardiac procedures.
San Francisco, CaliforniaAges 18 years+ - NCT07783802RecruitingPhase 2
Study of clazakizumab for adults with high inflammation and heart risk
This study tests whether clazakizumab can reduce the risk of heart attacks or strokes in people with high levels of inflammation (measured by a blood test called hsCRP) and conditions like heart disease, obesity, diabetes, high blood pressure, or kidney disease. If you qualify, you'll receive either the study drug or a placebo to see if it helps lower your risk.
Glendora, CaliforniaAges 18 years+ - NCT07725250Recruiting
AI-guided blood pressure trial for stage I-II hypertension
This study tests whether combining artificial intelligence with personalized medicine can help lower blood pressure in people with stage I or II hypertension (140/90 or higher). If you have high blood pressure and can walk without help, this trial may be for you.
La Jolla, CaliforniaAges 18 years+ - NCT07610278RecruitingPhase 2
Blood Pressure and Cholesterol Treatment Study
This study tests a combination of two new medications (QCZ484 and inclisiran) designed to lower both blood pressure and cholesterol levels. You may be a good fit if you have high blood pressure and high cholesterol that isn't fully controlled by current treatments.
Northridge, CaliforniaAges 18–75 - NCT07582523Enrolling by invitation
Heart Rhythm Monitoring at Home for High Blood Pressure
This study tests whether wearing a small heart rhythm patch at home can detect irregular heartbeats in people with high blood pressure. It may help catch heart rhythm problems early before they cause symptoms.
San Francisco, CaliforniaAges 60 years+ - NCT07398391Recruiting
Blood pressure care study in San Diego
This study tests a program to help people manage their blood pressure using video calls and home monitoring. You may join if you have high blood pressure and live in San Diego.
San Diego, CaliforniaAges 21 years+ - NCT07333183RecruitingPhase 2
Mosliciguat plus treprostinil for lung disease with pulmonary hypertension
This trial tests a new medicine called mosliciguat combined with an inhaled treatment (treprostinil) for people who have both scarring lung disease (interstitial lung disease) and high blood pressure in the lungs. It aims to see if this combination can improve how well you feel and function.
Santa Barbara, CaliforniaAges 18–85 - NCT07285655RecruitingPhase 3
Study of L606 for lung disease with high blood pressure in the lungs
This trial tests a new treatment called L606 for people who have both a type of lung disease (ILD) and high blood pressure in the lungs (PH). The goal is to see if it is safe and helps with exercise and breathing.
Los Angeles, CaliforniaAges 18–80 - NCT06340152Recruiting
Studying maternal health after preeclampsia
This trial follows women who have had preeclampsia to learn more about their health after pregnancy. It collects blood and tissue samples to find markers that could improve future care.
San Diego, CaliforniaAges 18–50
High blood pressure trials by city in California
Where these studies are running in California
Institutions with a site for the recruiting high blood pressure studies listed above.
- Cedars-Sinai Medical Center · 2 studies
- Stanford Health Care · 2 studies
- Stanford University · 2 studies
- University of California San Diego · 2 studies
- University of California, San Francisco · 2 studies
- Bayview Research Group
- Cedar-Sinai Medical Center
- Clinical Research Site
What taking part in a high blood pressure study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
High blood pressure trials in other states
Common questions
- Are there high blood pressure clinical trials in California?
- Yes. We're currently tracking 67 recruiting high blood pressure studies with a site in California, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a high blood pressure study in California?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in California to take part?
- Not necessarily. These studies have a site in California, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a high blood pressure trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New high blood pressure studies open in California regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.