Clinical trials
Mechanical Ventilation clinical trials
Below are recruiting mechanical ventilation clinical trials, each written for real people, not researchers. We’re tracking 266 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06203405Recruiting
Sedation guided by breathing effort in ICU patients
This trial tests a new way to manage sedation (medication to keep you calm and comfortable) for people on a breathing machine. The goal is to see if adjusting sedation based on your breathing effort leads to better outcomes and shorter time on the machine.
Bangkok, BangkokAges 18 years+ - NCT07277244Enrolling by invitation
Gentle breathing support during robot surgery
This study tests a low-pressure breathing method during robot-assisted surgery to see if it helps protect your lungs. It's for adults having abdominal or pelvic surgery expected to last at least 2 hours.
Boston, MassachusettsAges 18 years+ - NCT07339449Recruiting
Monitoring during surgery to reduce time on a breathing tube
This study tests whether special monitors used during major abdominal surgery can help high-risk patients wake up sooner and need a breathing tube for less time after the operation.
Zagreb, CroatiaAges 50 years+ - NCT07490925Recruiting
Breathing Machine Strategy to Protect the Heart in ARDS
This trial tests a special breathing machine strategy that uses pressure measurements from a small tube in your esophagus (food pipe) to protect your heart's right side while treating ARDS caused by pneumonia. It may help if you have severe lung failure and need a ventilator.
BeijingAges 18 years+ - NCT06391424Recruiting
Oxygen use and breathing effort during ventilator weaning
If you are on a breathing machine in the ICU and ready to try breathing on your own, this study looks at how much oxygen your body uses during that test. It may help doctors better understand when you are ready to come off the ventilator.
Leiden, South HollandAges 18 years+ - NCT07732114Recruiting
Liver vein vs. heart echo to check right heart function on a ventilator
This study compares a liver vein ultrasound method with a standard heart ultrasound for checking how well the right side of the heart is pumping in patients who are on a breathing machine (ventilator). If you are on a ventilator and can get a clear ultrasound of your heart and liver veins, you may be able to join.
Alexandria, Shebin El-KomAges 18 years+ - NCT05950893Recruiting
Testing a device to measure breathing effort on ventilators
This trial checks whether a tool (called PMIvent) can safely and accurately track how hard you are breathing while you are on a ventilator set to “pressure support.” If it works well, it may help clinicians better understand breathing effort during this common type of ventilator care.
BeijingAges 18–85 - NCT07437846Recruiting
How lung pressure settings affect breathing effort in ICU patients
This trial looks at how different breathing support settings (called PEEP) affect how hard your lungs have to work when you are on a breathing machine. The goal is to find the best setting to make breathing easier for you.
Santiago, Santiago MetropolitanAges 18 years+ - NCT07582913Recruiting
Manual vs. Automatic Breathing Support During Surgery in Older Adults
This study compares two ways of helping you breathe during anesthesia for surgery: one controlled by an anesthesiologist by hand, and one using an automatic machine. Researchers want to see which method works better and is safer for patients 65 and older.
Ankara, ÇankayaAges 65 years+ - NCT06053684Recruiting
Comparing two breathing machines for babies with bronchiolitis
This study tests if a new type of breathing machine (NAVA) works better than the standard machine for babies under 2 with severe bronchiolitis in the pediatric ICU. The goal is to see which machine helps babies breathe easier and avoid needing a breathing tube.
The Bronx, New YorkAges birth–2 years - NCT07071935RecruitingPhase 2
Early ventilation study for newly diagnosed ALS
This trial tests whether starting non-invasive ventilation (breathing support) early in ALS helps people breathe easier and live better. If you've been diagnosed with ALS in the last 6 months and haven't used a breathing machine before, you may qualify.
Hershey, PennsylvaniaAges 18 years+ - NCT06466980Recruiting
Study of ventilator-related events after cardiac arrest
This study looks at lung-related problems that can happen when someone is on a breathing machine after surviving a cardiac arrest. If you qualify, researchers will track your recovery to better understand how to prevent these complications.
Corbeil-EssonnesAges 18 years+ - NCT07630662Recruiting
Breathing Muscle Function and Ventilator Weaning Success
This study looks at whether testing the strength and function of your breathing muscles (diaphragm and chest wall muscles) can predict whether you're ready to come off a ventilator (breathing machine). The goal is to help doctors make better decisions about when patients are ready to breathe on their own.
CairoAges 18 years+ - NCT07490028Recruiting
Mucus stiffness in ventilated ICU patients
This study looks at how sticky or stretchy the mucus is in the lungs of patients who need a breathing machine (ventilator). The goal is to learn more about mucus properties, which could help improve breathing treatments in the future.
Aix-en-Provence, RechercheAges 18 years+ - NCT07568418Recruiting
Skin Response Monitoring in Ventilated Premature Babies
This study measures how a premature baby's skin responds to stress while on a breathing machine. Researchers want to understand if skin conductance (electrical activity of the skin) is a good way to detect pain and discomfort in ventilated babies.
Uppsala, UpplandAges 5 months+ - NCT06491017Recruiting
Better airway clearance for ventilated patients
This trial tests if a special machine (mechanical insufflation-exsufflation) can help remove thick mucus from the lungs of patients who are on a breathing tube and ventilator. The goal is to see if optimized settings clear more mucus than standard care.
BarcelonaAges 18 years+ - NCT06425354Recruiting
Can breathing machine energy predict lung inflammation?
This study looks at a new measure called 'mechanical power' (the energy from the breathing machine) to see if it can predict inflammation in the lungs and blood of patients with low oxygen levels. It may help doctors better understand how the breathing machine affects lung damage.
RomaAges 18 years+ - NCT06368089Recruiting
Breathing muscle training for patients on a ventilator
This study tests two types of breathing exercises for people who have been on a breathing machine (ventilator) for more than 48 hours and are ready to start breathing on their own. The goal is to see which exercise helps them get off the ventilator faster.
SongkhlaAges 40–80 - NCT07105202RecruitingPhase 4
Shorter weaning from ventilator with levosimendan
This study tests if a heart medication called levosimendan helps people get off the breathing machine (ventilator) faster. It's for people who have been on a ventilator for more than 48 hours and have already tried and failed to breathe on their own.
Arnhem, GelderlandAges 18 years+ - NCT06719258Recruiting
Trial on heated humidifiers for breathing tubes
This trial studies how heating and adding moisture to the air breathed through a breathing tube (called a heated humidifier) affects patients in intensive care. It focuses on people who need the breathing tube for a longer time or special protective settings.
Québec, QuebecAges 18 years+ - NCT07453966Recruiting
Lung vibration therapy for people on breathing machines with lung infection
This study tests a device that delivers gentle vibrations to the lungs to help clear infection in people who are on a breathing machine. It may help improve oxygen levels and recovery.
Wuhan, HubeiAges 18 years+ - NCT05405491Recruiting
DNA test to guide antibiotic use for pneumonia in ICU patients
This study tests whether using a DNA test on lung fluid can help doctors choose better antibiotics for pneumonia in ICU patients with weakened immune systems. It may lead to more effective treatment and fewer side effects.
LilleAges 18 years+ - NCT04534296Recruiting
Early mobilization for breathing muscles in critically ill children
This study looks at whether starting movement early in the first day of breathing support can help keep the diaphragm (a key breathing muscle) working better in critically ill children. The researchers will check diaphragm thickness using ultrasound and compare it to usual care.
ShanghaiAges 6 months–12 years - NCT07363902Recruiting
Electrical muscle stimulation study for breathing support
This study tests a new device that uses mild electrical pulses to strengthen the muscles used for breathing in people who are on a ventilator. It aims to help them recover faster.
Barcelona, BarcelonaAges 18 years+
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Common questions
- Are there clinical trials for mechanical ventilation?
- Yes. Clin2 currently lists 266 recruiting mechanical ventilation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a mechanical ventilation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a mechanical ventilation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Mechanical Ventilation Complication
- Mechanical Ventilation Weaning
- Invasive Mechanical Ventilation
- Mechanical Ventilation Pressure High
- Prolonged Mechanical Ventilation
- Weaning Failure of Mechanical Ventilation
- Weaning Invasive Mechanical Ventilation
- Respiratory Insufficiency Requiring Mechanical Ventilation
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.