Clinical trials
Mechanical Ventilation clinical trials
Below are recruiting mechanical ventilation clinical trials, each written for real people, not researchers. We’re tracking 266 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07339397Recruiting
Joint stiffness in ICU patients on breathing machines
This trial studies how common joint stiffness becomes in ICU patients who are on a breathing machine and cannot move for at least 7 days. It may help doctors better prevent and treat this problem.
Elâzığ, ElaziğAges 18 years+ - NCT07596589RecruitingPhase 3
Remimazolam sedation for breathing-machine patients in ICU
This study tests whether a sedative medication called remimazolam helps patients on breathing machines (ventilators) in the ICU recover better and have fewer complications. You would receive this medication to keep you calm and comfortable while on the ventilator.
Nanjing, JiangsuAges 18 years+ - NCT06581939Recruiting
Early rehab with nutrition after ICU ventilation
This study tests whether starting physical therapy and tailored nutrition early and continuing for a longer time helps people recover after being on a breathing machine and blood pressure support in the ICU.
AlbiAges 18 years+ - NCT06575530RecruitingPhase 4
Remimazolam for sedation after non-cardiac surgery
This trial tests a sedative called remimazolam besylate in patients who need a breathing tube and light sedation after non-cardiac surgery. The goal is to see if it works well and is safe.
Beijing, Beijing MunicipalityAges 18–64 - NCT05857774Recruiting
Study breathing muscle changes in ICU patients on ventilation
This study looks at how the muscles used for breathing work and change in ICU patients who are placed on breathing machines, then follows outcomes after they leave the hospital. It may help doctors better predict recovery and long-term health after ventilation.
Toronto, OntarioAges 18 years+ - NCT07375667Recruiting
Airway suction guidance in ventilated patients
This trial uses dynamic airway resistance and machine learning to guide when sputum suction is needed in ventilated patients with ARDS, AECOPD, or severe pneumonia.
Bengbu, AnhuiAges 18–90 - NCT06367946Recruiting
Why ventilators can hurt older lungs
This study looks at how mechanical ventilation affects the lungs of elderly people. Researchers will study lung tissue and blood samples from patients having surgery to find ways to prevent lung injury.
ShanghaiAges Any age - NCT05412810Recruiting
Test air-biomarker changes during ICU breathing machine use
This study looks for chemical “biomarkers” in samples taken during ICU care to better understand what happens during mechanical ventilation. It may help future care by identifying signs that could guide safer breathing-machine treatment.
Columbus, OhioAges 18–110 - NCT05751863Recruiting
Sedation-first vs usual care in ventilated trauma patients
This study compares how pain medicine and calming medicine are started in critically injured (trauma) adults who are on a breathing machine. It aims to see whether a specific “analgesia-first” approach can improve comfort and support breathing weaning.
Long Beach, CaliforniaAges 18 years+ - NCT02514655Recruiting
Device to control breathing-tube cuff pressure to prevent pneumonia
This trial tests a simple device that helps keep the cuff pressure on a breathing tube at the right level. The goal is to reduce the risk of pneumonia that can happen in people on a ventilator.
ParisAges 18 years+ - NCT06474559Recruiting
Comparing two breathing tubes during urology surgery
This trial compares a special breathing tube (LMA Protector) with a standard tube (ETT) to see which one works better for patients having planned urological surgery. It checks how easy it is to breathe with the machine and the risk of stomach contents getting into the lungs.
PátraiAges 18 years+ - NCT06923267Recruiting
Ultrasound to check heart function during breathing trials
This trial tests if using ultrasound to monitor your heart during a breathing test can help predict if you will need the breathing tube again. It is for people on a ventilator for at least 24 hours who are at higher risk of needing the tube reinserted.
OrléansAges 18 years+ - NCT04080440Recruiting
Checking readiness to remove the breathing tube after brain injury
This study looks at how to judge when it is safe to remove the breathing tube in people in the ICU after a brain injury. It may help improve timing and safety of extubation, when supported by a breathing trial and clinical stability.
AngersAges 18–75 - NCT07001696Recruiting
Predicting breathing support needs with chest X-ray and blood gas
This trial looks at whether combining a chest X-ray and a blood gas test can help doctors decide if a critically ill patient needs a breathing machine (mechanical ventilation). It aims to find a better way to make this important decision.
Zagazig, Al SharqiaAges 18 years+ - NCT06790875Recruiting
Comparing two ventilator settings for lung health in ARDS
This study tests two methods of adjusting a ventilator to see which one may better protect the lungs of patients with ARDS. It will help doctors learn how to set the machine to reduce strain on the lungs.
Wuhan, HubeiAges 18–80 - NCT07077174Recruiting
Permissive lung-protective ventilation for critically ill patients on a breathing machine
This trial tests whether a more lenient approach to lung-protective ventilation can improve outcomes for patients who need a breathing machine (ventilator) in the intensive care unit. It aims to find a balance that is safer for the lungs while still being effective.
AlmeloAges 18 years+ - NCT07409727RecruitingPhase 4
Acetylcysteine inhalation to prevent pneumonia in ventilated patients
This trial tests if breathing in a medication called acetylcysteine can help prevent lung infections in patients who are on a breathing machine. If you or a loved one is on a ventilator, this treatment might reduce the chance of getting ventilator-associated pneumonia.
CairoAges 18–64 - NCT07245888Recruiting
Studying pneumonia in ventilated ICU patients
This study looks at different types of lung infections in ICU patients on breathing machines. By analyzing fluid from your lungs, researchers hope to better understand pneumonia and improve treatment.
LimogesAges 18 years+ - NCT06791915Recruiting
Comparing breathing method during heart ablation for AFib
This trial studies two ways of using a breathing machine during a heart procedure called radiofrequency ablation for atrial fibrillation (AFib). It aims to find which method is better and safer.
KocaeliAges 18 years+ - NCT07182851Recruiting
Pain in patients on breathing machines in the ICU
This study looks at pain in patients who are on a breathing machine (ventilator) in the intensive care unit. It aims to understand pain better so doctors can help manage it more effectively.
Rio de Janeiro, Rio de JaneiroAges 18 years+ - NCT06662630Recruiting
Oscillatory ventilation study for ICU patients on breathing machines
This study tests a new breathing method (high-frequency oscillatory ventilation) for patients in the ICU who need a breathing tube. It looks at how safe it is and how it affects the body, and is for people with certain lung problems like ARDS or collapsed lungs.
Shanghai, Shanghai MunicipalityAges 20–90 - NCT06971042Recruiting
Using lung ultrasound to find ARDS early in ventilated patients
This study compares lung ultrasound with CT scans to detect ARDS (a serious lung injury) early in patients on a breathing machine. The goal is to see if ultrasound can provide a faster, safer way to diagnose ARDS.
TantaAges 22–80 - NCT05963737Recruiting
Testing a ventilator setting change for people on pressure support
This trial tests whether changing a ventilator setting (pressure support settings) is safe and helpful for people who need mechanical ventilation for more than 48 hours. It’s mainly for adults whose breathing support is expected to continue, and who don’t have several specific lung, brain, or nerve problems.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07109570Recruiting
Checking breathing effort in ICU patients on a ventilator
This trial measures how your breathing muscles work while we try taking you off the breathing machine. The results could help doctors predict when you're ready to breathe on your own.
LeidenAges 18 years+
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Common questions
- Are there clinical trials for mechanical ventilation?
- Yes. Clin2 currently lists 266 recruiting mechanical ventilation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a mechanical ventilation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a mechanical ventilation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Mechanical Ventilation Complication
- Mechanical Ventilation Weaning
- Invasive Mechanical Ventilation
- Mechanical Ventilation Pressure High
- Prolonged Mechanical Ventilation
- Weaning Failure of Mechanical Ventilation
- Weaning Invasive Mechanical Ventilation
- Respiratory Insufficiency Requiring Mechanical Ventilation
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.