Clinical trials
Muscle Atrophy or Weakness clinical trials
Below are recruiting muscle atrophy or weakness clinical trials, each written for real people, not researchers. We’re tracking 163 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07404956Recruiting
Comparing surgical and N95 masks for operating room nurses
This study checks how wearing a surgical mask or an N95 mask affects the air quality during surgery (called surgical smoke). It is for operating room nurses who work with surgical smoke regularly.
Bartın, BartınAges 18 years+ - NCT07538830Recruiting
Probiotic supplement for muscle strength in older adults
This study tests whether a specific probiotic (a beneficial bacteria called Lactiplantibacillus plantarum) can help improve muscle strength and physical function in adults aged 50–84. The probiotic may work by improving gut health, which could support muscle health.
BusanAges 50–85 - NCT06487728Enrolling by invitation
Predicting muscle weakness in ICU patients with urine test
This study checks if a urine test and muscle measurements can help predict muscle weakness in critically ill patients. It aims to find an easier way to identify who might get weaker in the ICU.
Zagazig, Sharqia ProvinceAges 18 years+ - NCT03201094Recruiting
NMES and whey protein for recovery after aneurysmal brain bleed
This pilot study tests whether a therapy that gently stimulates nerves (NMES) and a whey-protein supplement (HPRO) can improve recovery after an aneurysmal subarachnoid hemorrhage (SAH), a type of bleeding around the brain. Participants are usually treated soon after the bleed and stay in the ICU long enough for the study measures.
Baltimore, MarylandAges 18 years+ - NCT05008705Recruiting
Protein and muscle stimulation for hospitalized seniors
This trial tests whether increasing protein intake plus using a gentle electrical muscle stimulation device can help maintain or build muscle mass in older adults while they are hospitalized. It may help prevent muscle loss that can happen after short hospital stays.
São PauloAges 65 years+ - NCT05211661Recruiting
Study breathing muscle changes in people on a ventilator
This study looks at how the diaphragm (a key breathing muscle) changes during and after being on a breathing machine in the ICU. It may help researchers understand why breathing can get weaker after ventilation and how to measure it safely (including with MRI).
AachenAges 18–75 - NCT05279547Recruiting
Bed-cycle exercise study to test muscle oxygen during ICU care
This trial tests whether brief “interval” bed-cycling changes how well your leg muscles use oxygen compared with steady cycling. It’s meant for carefully selected ICU patients who can safely do active cycling while on ventilator support.
LeuvenAges 18 years+ - NCT05671614Recruiting
Prevent muscle stem cell failure after critical illness
This trial studies ways to improve recovery of skeletal muscle in people who have been very sick in the ICU. It focuses on preventing problems with the body’s muscle “repair cells” after critical illness.
Prague, Czech RepublicAges 18 years+ - NCT05725928Recruiting
Walking-support program for older hospitalized patients
This study tests whether extra help and guidance to walk while you’re in the hospital can improve health and recovery. It’s for older adults who can safely do some walking after being admitted for a medical problem.
Springfield, MassachusettsAges 65 years+ - NCT05754632Recruiting
Blood flow restriction exercises after ACL surgery in teens
This trial tests whether a special type of exercise that uses a cuff (blood flow restriction training, or BFRT) can help teens recover after ACL reconstruction. It’s designed to see if adding BFRT to standard rehab improves strength and return to sport.
Farmington, ConnecticutAges 12–18 - NCT05869812RecruitingPhase 2
HMB supplement study to help recovery after surgery
This trial tests whether taking an HMB supplement after surgery can help improve muscle size and function during recovery. It may be helpful if you are a female athlete planning rehab at a specific physical therapy clinic.
Overland Park, KansasAges 18–45 - NCT05877846Recruiting
Personalized care to improve physical function in older adults
This study looks at precision (personalized) approaches to help older adults improve physical function. It may include giving a specific supplement depending on lab results, and it requires regular study visits and ability to complete procedures.
Chapel Hill, North CarolinaAges 65–85 - NCT06050668RecruitingPhase 2
Amino acid supplement study for broken hip in older adults
This study tests whether giving extra essential amino acids (building blocks of protein) to older adults hospitalized with a broken femur (thigh bone) can improve their recovery. If you are 65 or older, broke your femur from a simple fall, and are having surgery to fix it, you may be able to join.
Iowa City, IowaAges 65 years+ - NCT06053229Recruiting
Massage therapy for leg muscle health during immobilization
This trial examines if percussive massage can help maintain leg muscle mass and strength when your leg is immobilized (e.g., in a cast). It aims to see if this therapy could reduce muscle loss during periods of disuse.
Provo, UtahAges 18–50 - NCT06129110Recruiting
Weight loss and muscle fat study for adults aged 18-70
This study looks at how losing weight affects the fat that sits inside your muscles (called intermuscular fat). It might help people with overweight to better understand how weight loss can improve muscle health.
Aurora, ColoradoAges 18–70 - NCT06235736Recruiting
Do ACL tears cause weakness in the soleus muscle?
This study looks at whether people with ACL tears have weakness in a specific calf muscle called the soleus. If you have an ACL tear, you will do strength tests to compare with healthy individuals.
LiverpoolAges 18–55 - NCT06363357Recruiting
Shoulder brace study for arm weakness from nerve or muscle diseases
This study tests a fabric shoulder brace that moves like a muscle. It may help people with nerve or muscle diseases improve arm movements like reaching and lifting.
Seoul, Jongno-guAges 10 years+ - NCT06395506Recruiting
Exercise and creatine for breast cancer survivors
This trial tests if adding creatine supplements to a virtual exercise program helps breast cancer survivors recover after chemotherapy. Participants will attend online exercise sessions three times a week and take creatine by mouth.
Galveston, TexasAges 18–75 - NCT06441422Recruiting
Blood flow training for people with disabilities
This trial tests if using a blood pressure cuff during arm exercises can help people with disabilities build muscle strength. It's designed to be safe and effective for those who can do upper body movements.
Milwaukee, WisconsinAges 18 years+ - NCT06573086Recruiting
Resistance training, detraining, and retraining
This study looks at how your body responds to resistance training, a break from training, and then training again. It is for healthy adults who already completed a previous exercise study.
Jyväskylä, Central FinlandAges 18–50 - NCT06607913Recruiting
Exercise after hospitalization for kidney patients
This study tests whether a personalized exercise program can help adults over 55 with chronic kidney disease regain strength and mobility after a hospital stay.
Aurora, ColoradoAges 55 years+ - NCT06626919RecruitingPhase 1
A cell therapy trial for generalized myasthenia gravis
This trial tests a new cell therapy called anitocabtagene autoleucel (anito-cel) for people with generalized myasthenia gravis (gMG) that is not well controlled with current treatments. The goal is to see if it can reduce symptoms and improve quality of life.
Los Angeles, CaliforniaAges 18 years+ - NCT06765642Recruiting
Brain stimulation for hand strength after stroke
This study tests whether a safe, non-invasive brain stimulation technique (called rTMS) can improve hand strength and movement in people who have had a stroke at least 3 months ago. The treatment is delivered through a coil placed on the scalp and does not require surgery.
Durham, North CarolinaAges 21 years+ - NCT06772922Recruiting
Pulmonary and heart rehab program testing combined exercise
This trial studies a combined lung and heart rehabilitation program for people with lung diseases (like COPD, asthma, or fibrosis) or heart conditions (like heart attack, bypass surgery, or heart failure). The goal is to see if a special exercise program can improve your health and quality of life.
Campinas, São PauloAges 18 years+
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Common questions
- Are there clinical trials for muscle atrophy or weakness?
- Yes. Clin2 currently lists 163 recruiting muscle atrophy or weakness studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a muscle atrophy or weakness trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a muscle atrophy or weakness trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.