Clinical trials
Muscle Atrophy or Weakness clinical trials
Below are recruiting muscle atrophy or weakness clinical trials, each written for real people, not researchers. We’re tracking 163 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06781060Recruiting
Nerve stimulation for sciatic nerve injury in children
This trial tests if electrical nerve stimulation can help children aged 3 to 19 who have nerve damage in the leg caused by an injection. The goal is to improve nerve healing and leg function.
Multan, Punjab ProvinceAges 3–19 - NCT06786390Recruiting
Walking recovery after muscle weakness
This trial tests if a walking program combined with electrical stimulation can help people recover walking ability after critical illness. It is for patients who developed limb weakness in the hospital and were independent before their illness.
MilanAges 18–85 - NCT07188350Recruiting
Electrical muscle stimulation for patients on a breathing machine
This trial tests whether low-level electrical pulses to the leg muscles can help prevent weakness in patients who need a breathing tube (ventilator) for more than 48 hours. It aims to see if this treatment helps patients recover faster.
Porto Alegre, Rio Grande do SulAges 18 years+ - NCT07413302Recruiting
Predicting recovery after back surgery for leg weakness
This study looks at which factors before surgery help predict how well leg weakness improves after a single-level microdiskectomy (minimally invasive back surgery for a slipped disk). It may help you understand what to expect if you are having this procedure.
KavalaAges 18 years+ - NCT06998134Recruiting
Exoskeleton walking training for children and young adults
This trial tests whether a robotic leg exoskeleton can help improve walking in children and young adults with certain conditions (like cerebral palsy, muscular dystrophy, spina bifida, or spinal cord injury) or those with no walking issues. The goal is to find out if the exoskeleton is safe and effective for everyday use, especially in younger people who might lose the ability to walk as they get older.
Bethesda, MarylandAges 5–25 - NCT07179042Enrolling by invitationEarly Phase 1
Metformin for hip fracture recovery in older adults
This study tests whether the diabetes drug metformin can help older adults recover better after hip fracture surgery. To join, you need to be 60+, have had a low-energy hip fracture fixed within 3 days, and be generally healthy without diabetes or kidney issues.
Salt Lake City, UtahAges 60–90 - NCT06977958Enrolling by invitation
Gluteal enhancement trial for non-active women
This trial tests a program called NASM OPT to see if it can improve hip appearance in women who haven't exercised for the last 6 months. It might help you if you're looking to reshape your hips safely.
Ferdows, South Khorasan ProvinceAges 20–45 - NCT06977919Enrolling by invitation
New exercise method for chest firmness and shape
This trial tests a new technique (called NASM OPT) to help improve the shape and firmness of your chest. It is for women who have not been exercising and who want to enhance their chest appearance without using surgery.
Zahedan, Sistan and BaluchestanAges 20–45 - NCT06492057Enrolling by invitation
EMS muscle training for astronauts in space
This trial tests if a special muscle stimulation device called EMS can help astronauts stay fit during spaceflight. It may prevent muscle loss in zero gravity.
Mitte, State of BerlinAges 40–60 - NCT05513417Enrolling by invitation
Digital pelvic health program for women with pelvic pain
This study tests a digital (phone/app-based) program to help women with pelvic pain or pelvic health symptoms. It may help by guiding pelvic-focused exercises and care, especially if you’re recovering from pelvic surgery or managing ongoing symptoms.
Draper, UtahAges 18–99 - NCT07094971Recruiting
Muscle toning and strengthening for abs, thighs, and glutes
This trial tests a device treatment to strengthen and tone your abdomen, quadriceps, and glutes. It is for people who want to improve muscle definition without surgery or major lifestyle changes.
Eugene, OregonAges 25–60 - NCT01403402Recruiting
Study of congenital muscle disease patients and their families
This trial collects health information from patients with certain inherited (genetic) muscle diseases and from their families. It may help researchers better understand the disease and improve care by learning what symptoms and treatments patients experience over time.
Lakewood, CaliforniaAges Any age - NCT07221669RecruitingPhase 3
Pre-symptomatic salanersen study for babies with SMA
This trial tests if the drug salanersen can help movement and is safe when given to babies diagnosed with spinal muscular atrophy before they show symptoms. It's for very young infants with specific genetic types of SMA.
Chicago, IllinoisAges birth–1 month - NCT07729774Recruiting
Spray-and-stretch vs. gentle pressure for back pain
This study compares two hands-on techniques—spray-and-stretch and strain-counterstrain—to see which better relieves nonspecific low back pain. It may help if you have muscle-related back pain without nerve problems or other serious conditions.
Multan, Punjab ProvinceAges 35–50 - NCT04944940Recruiting
Study tests blood, scans, and genes in SBMA and healthy men
This study looks for early “biomarkers” (measurable signs) in the body using blood tests, imaging scans, and sometimes other procedures in men with genetically confirmed spinal and bulbar muscular atrophy (SBMA). The results may help future drug studies by showing better ways to track disease changes over time.
Bethesda, MarylandAges 18–120 - NCT05394506Recruiting
Study of factors that affect muscle laminopathy with LMNA changes
This study looks at what influences the course of a muscle disease caused by an LMNA genetic change (a type of laminopathy). It may help researchers better understand the disease and how it affects muscle and sometimes breathing or heart function.
Bron, Auvergne-Rhône-AlpesAges 2 years+ - NCT06169046RecruitingPhase 2
Clenbuterol for spinal and bulbar muscular atrophy
This study tests if clenbuterol (a medication that may help strengthen muscles) can improve symptoms in people with spinal and bulbar muscular atrophy (SBMA, also called Kennedy's disease). It compares clenbuterol to a placebo (a dummy pill) over several months.
Padova, PDAges 18–75 - NCT06532123Recruiting
Study on improving muscle control for bowel leakage
This trial tests a treatment to strengthen the muscles that control bowel movements in people with weak anal sphincters. It may help those who have trouble holding in stool or gas.
Milwaukee, WisconsinAges 18 years+ - NCT06765551Recruiting
AI muscle ultrasound for weakness after surgery
This study uses artificial intelligence (AI) to analyze muscle ultrasound images, aiming to better identify muscle weakness that can develop after major surgery in the ICU. This could help doctors assess and treat patients more effectively.
Jena, ThuringiaAges 18 years+ - NCT06862596RecruitingPhase 2/Phase 3
Mexiletine for spinal and bulbar muscular atrophy
This trial tests whether mexiletine hydrochloride can help men with spinal and bulbar muscular atrophy (SBMA) by improving muscle strength and function. It may be an option if you have mild to moderate symptoms and meet heart and medication safety checks.
Bunkyō CityAges 18–80 - NCT07191743Recruiting
Functional Assessment in ICU Patients
This study observes how well adults in the intensive care unit (ICU) can function in daily activities, like moving and caring for themselves. It aims to understand recovery and may help improve care for future ICU patients.
Rio de Janeiro, Rio de JaneiroAges 18 years+ - NCT07220005Recruiting
Focused ultrasound for stroke recovery
This study tests a gentle sound wave therapy (focused ultrasound) to see if it can help improve arm movement in people who had a stroke at least 6 months ago. It aims to find the best settings for this treatment.
Durham, North CarolinaAges 21 years+ - NCT07349706Recruiting
Breathing exercise for dementia risk reduction
This trial tests a simple breathing exercise done for about 5–10 minutes each day for 8 weeks. It aims to see if this exercise can reduce your risk of dementia. If you are between 60 and 80 years old and have at least one risk factor for dementia, this study may be a fit for you.
Tallahassee, FloridaAges 60–80 - NCT07413718Recruiting
Breathing muscle training for ALS patients
This study tests whether a special breathing muscle training can help people with ALS maintain lung function. It may benefit patients diagnosed recently with spinal ALS and good breathing capacity.
Donostia / San Sebastian, GipuzkaAges 18–85
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Common questions
- Are there clinical trials for muscle atrophy or weakness?
- Yes. Clin2 currently lists 163 recruiting muscle atrophy or weakness studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a muscle atrophy or weakness trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a muscle atrophy or weakness trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.