Clinical trials
Muscle Atrophy or Weakness clinical trials
Below are recruiting muscle atrophy or weakness clinical trials, each written for real people, not researchers. We’re tracking 162 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04944940Recruiting
Study tests blood, scans, and genes in SBMA and healthy men
This study looks for early “biomarkers” (measurable signs) in the body using blood tests, imaging scans, and sometimes other procedures in men with genetically confirmed spinal and bulbar muscular atrophy (SBMA). The results may help future drug studies by showing better ways to track disease changes over time.
Bethesda, MarylandAges 18–120 - NCT07729774Recruiting
Spray-and-stretch vs. gentle pressure for back pain
This study compares two hands-on techniques—spray-and-stretch and strain-counterstrain—to see which better relieves nonspecific low back pain. It may help if you have muscle-related back pain without nerve problems or other serious conditions.
Multan, Punjab ProvinceAges 35–50 - NCT07444450RecruitingPhase 3
Study of salanersen for babies with SMA previously treated with gene therapy
This study tests a new medicine called salanersen in babies who have already received gene therapy for SMA. It aims to see if adding salanersen is safe and effective.
Flower Mound, TexasAges birth–7 months - NCT07853755Recruiting
Pelvic muscle training with mental practice for bladder leaks after menopause
This study tests whether adding mental practice (imagining the exercises) to standard pelvic floor muscle training helps postmenopausal women with stress urinary incontinence (leaking urine when you cough, sneeze, or exercise) improve their symptoms. It aims to see if this extra mental approach makes the training more effective.
Istanbul, IstanbulAges 45–65 - NCT07419633Recruiting
Study on supplements to improve strength and thinking in older adults
This trial tests if two supplements, HMB and 2-HOBA, taken alone or together, can help improve muscle strength and mental function in healthy adults over 65. The goal is to see if these supplements can improve overall quality of life.
Montreal, QuebecAges 65 years+ - NCT07368920Recruiting
TENS for low back pain in adults
This study tests if a non-invasive device called TENS (which uses gentle electrical pulses) can help relieve low back pain that comes from muscle knots or tight bands. The device is applied to the skin over the painful area.
Xi'an, ShaanxiAges 18–65 - NCT07362875Recruiting
Muscle imaging study for myotonic dystrophy
This study uses MRI scans to measure muscle changes in people with myotonic dystrophy (DM1 or DM2) and healthy volunteers. The goal is to find better ways to track the disease over time.
Winston-Salem, North CarolinaAges 18–65 - NCT07328126Recruiting
Muscle energy technique for low back pain relief
This trial tests a gentle muscle stretching method (muscle energy technique) on the latissimus dorsi muscle to see if it reduces pain, improves daily function, and increases spine movement in people with long-term low back pain.
Rawalpindi, Punjab ProvinceAges 30–55 - NCT06767631Recruiting
Muscle and nerve changes after botox for stroke foot tightness
This study looks at how botulinum toxin (botox) injections affect the muscles, tendons, and nerves in the lower leg of people who have had a stroke and have a tight, twisted foot (equinovarus). It aims to understand these changes to improve future treatments.
LeuvenAges 40–60 - NCT07555795Recruiting
Game-Based Wearable Sensors to Help Core Muscles and Back Pain
This study tests a wearable belt with sensors and haptic feedback (gentle vibrations) combined with interactive gaming to help strengthen your core muscles and reduce lower back pain. The goal is to make exercise more engaging and effective for chronic back pain.
LondonAges 18 years+ - NCT07267910Enrolling by invitation
Measuring inner ear function with weak electrical stimulation
This study uses a weak electrical current to test how well your inner ear balance system works. It may help people with certain inner ear conditions like vestibular schwannoma or vestibular neuritis.
HelsinkiAges 18–70 - NCT07259577Recruiting
Vagus nerve stimulation for stroke recovery
This trial tests whether stimulating the vagus nerve can improve arm movement, breathing, and quality of life in people who had a stroke more than 6 months ago. It involves a non-invasive device that gently stimulates a nerve in the neck during therapy sessions.
Istanbul, IstanbulAges 18–70 - NCT07233161Recruiting
Modified arm therapy for early stroke recovery
This trial tests a modified version of constraint-induced movement therapy to help improve arm function in people who have had a stroke within the last 15 days. You may benefit if you have weakness in one arm and can follow simple instructions.
Barcelona, BarcelonaAges 18 years+ - NCT07220915RecruitingPhase 3
Study of Panzyga to prevent infections in people with weak immune systems
This trial tests if a medication called Panzyga can help prevent infections in people with autoimmune conditions who have low antibody levels after B-cell therapy. It may be an option if you have a condition like multiple sclerosis, rheumatoid arthritis, or lupus.
Glendale, ArizonaAges 18 years+ - NCT07017517Recruiting
Exercise therapy for weakness after sepsis in the ICU
This trial tests whether adding physical therapy early in the ICU can help people with sepsis regain strength and reduce muscle weakness. It focuses on patients who need a breathing tube for at least a week and have a high level of organ failure.
Santiago, Metropolitan RegionAges 18 years+ - NCT07176988Recruiting
Voice therapy study for certain voice problems
This study tests a behavioral voice therapy approach for people with voice issues caused by muscle tension or benign vocal fold lesions. It aims to improve communication and requires participants to attend sessions and practice with a smartphone.
Atlanta, GeorgiaAges 16–65 - NCT07162948Recruiting
Home monitoring technology for ICU recovery
This study tests a smart technology box that helps monitor your health at home after a stay in the ICU. It may help you and your doctors keep track of your recovery more easily.
Leiden, South HollandAges 18 years+ - NCT07150650Enrolling by invitation
Biomarkers for ICU weakness in children on breathing machines
This study looks for early warning signs (biomarkers) of muscle weakness that can happen in children who need a breathing machine for more than a few days. If your child is in the PICU on a ventilator for at least 3 days, this team may be able to test for clues that help prevent or manage this weakness.
Shanghai, Shanghai MunicipalityAges 1 month–18 years - NCT07138963Recruiting
Gene study in children with congenital muscle weakness
This study looks at how genes affect symptoms in children with congenital myopathies or congenital muscular dystrophies. It may help doctors better understand these conditions.
CairoAges 1–18 - NCT07130929Recruiting
Electrical stimulation for muscle weakness after severe stroke
This trial tests if a gentle electrical stimulation technique, called functional electrical stimulation, can help patients recover muscle strength after a severe stroke that left them weak in the arms and legs. It may offer a new way to aid rehabilitation in the early months after stroke.
Florence, FIAges 18–80 - NCT06955897Recruiting
Study of Fatigue in SMA Patients on Nusinersen
This study looks at how tired you feel during physical activities while being treated with nusinersen (Spinraza) for spinal muscular atrophy (SMA). The goal is to understand how well the treatment helps with daily energy levels.
New York, New YorkAges 12 years+ - NCT07089134Recruiting
Virtual reality for ICU patient satisfaction and recovery
This trial tests whether using virtual reality (wearing a headset to see calming scenes) helps people in the ICU feel better, recover faster, and be more satisfied with their care. It is for awake and stable ICU patients who can follow simple instructions.
São Paulo, São PauloAges 18 years+ - NCT07047300Recruiting
How a heel lift insole affects walking for healthy adults
This study tests whether wearing a heel lift insole changes how your legs and lower back move while walking. It may help understand if such insoles can benefit people with certain conditions, but right now it only includes healthy volunteers.
Giza, Giza GovernorateAges 18–25 - NCT06973746Recruiting
Sitting up in a chair in the ICU for patients on breathing machines
This study tests whether getting patients who are on a breathing machine to sit in a chair helps them recover better. It looks at whether this simple activity can improve how well they get back to normal function.
Orléans, Centre-Val de LoireAges 18 years+
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Common questions
- Are there clinical trials for muscle atrophy or weakness?
- Yes. Clin2 currently lists 162 recruiting muscle atrophy or weakness studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a muscle atrophy or weakness trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a muscle atrophy or weakness trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.