Clinical trials
Muscle Atrophy or Weakness clinical trials
Below are recruiting muscle atrophy or weakness clinical trials, each written for real people, not researchers. We’re tracking 164 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07413718Recruiting
Breathing muscle training for ALS patients
This study tests whether a special breathing muscle training can help people with ALS maintain lung function. It may benefit patients diagnosed recently with spinal ALS and good breathing capacity.
Donostia / San Sebastian, GipuzkaAges 18–85 - NCT07244861Enrolling by invitation
TENS for neck muscle stiffness and pain
This study tests whether a gentle electrical stimulation device (TENS) applied to the neck can reduce muscle stiffness and pain in people with ongoing neck pain. If you have had neck pain for at least 6 weeks and are willing to avoid certain medications the day before, you may be able to join.
ErzurumAges 18–50 - NCT07150637Enrolling by invitation
Predicting muscle weakness in children on a breathing machine
This study aims to predict muscle weakness that can happen to children on breathing machines in the ICU. It could help doctors start treatments earlier to prevent this weakness.
Shanghai, Shanghai MunicipalityAges 1 month–18 years - NCT06774157Enrolling by invitation
Allyane therapy for knee sprain recovery
This trial tests if the Allyane procedure helps people with a recent knee sprain regain thigh muscle strength. It may be an option if you have weakness in the front thigh muscle compared to your uninjured leg.
LyonAges 18–35 - NCT06669494Enrolling by invitation
Study on ICU muscle weakness detection and monitoring
This study aims to find better ways to detect and track muscle weakness that can happen during an ICU stay. If you or your loved one is in the ICU, this research could help improve early diagnosis and care.
Seoul, SeoulAges 18 years+ - NCT07731035Recruiting
Balance and foot exercises for ankle instability
This study tests if combining core stability training with foot exercises helps people with chronic ankle instability. It compares these exercises to either core training alone or no treatment to see which works best.
Al MansurahAges 18–44 - NCT06958666Recruiting
Comparing two breathing exercises for COPD symptoms
This study compares two breathing exercise methods (DITM vs IMT) for people with COPD to see which helps improve symptoms and quality of life better. It's for people who are already using a specific type of inhaler.
Hangzhou, ZhejiangAges 40 years+ - NCT07220915RecruitingPhase 3
Study of Panzyga to prevent infections in people with weak immune systems
This trial tests if a medication called Panzyga can help prevent infections in people with autoimmune conditions who have low antibody levels after B-cell therapy. It may be an option if you have a condition like multiple sclerosis, rheumatoid arthritis, or lupus.
Scottsdale, ArizonaAges 18 years+ - NCT07636967Recruiting
Ankle Muscle Strength in Chronic Low Back Pain
This study measures the strength and function of ankle muscles in people with chronic low back pain lasting over 3 months. Understanding how ankle muscles work may help explain why some people develop long-term low back pain.
Tanta, Gharbia GovernorateAges 20–25 - NCT07560020RecruitingPhase 2
Surlorian for RYR1 muscle weakness: strength and safety study
This trial tests whether a new drug called Surlorian can improve muscle strength in adults with a rare genetic muscle condition (RYR1-related myopathy). You'd receive either the drug or a placebo and be monitored for safety and changes in muscle function.
Marseille, Bouches-du-RhôneAges 18–65 - NCT03872102Recruiting
Brain imaging study to track Parkinson-related disease changes
This study uses brain scans and clinical check-ins to better diagnose and predict how Parkinson-related conditions may progress over time. It may help researchers find markers that explain why symptoms change, and could improve future care.
Dallas, TexasAges Any age - NCT03980457Recruiting
Exoskeleton walking therapy for stroke recovery
This trial studies whether assisted walking training with an exoskeleton can improve recovery after stroke, especially for walking and daily function. You may be offered therapy once you are medically stable, able to stand, and able to participate safely.
Oklahoma City, OklahomaAges 18–90 - NCT04158180Recruiting
Questionnaire study for diastasis recti in adult women
This trial is testing and verifying a Spanish questionnaire about diastasis recti (a separation in the abdominal muscles). It may help by creating a tool that doctors and researchers can use to better understand symptoms and severity.
Plasencia, CáceresAges 18–65 - NCT04521972Recruiting
Testing how room light affects labor and uterine contractions
This study looks at whether changing the light you’re exposed to (using blue-filter glasses and adjusting lighting) changes uterine contractions and how labor progresses. You’d also track your lighting and use a home monitor that measures contraction activity.
East Lansing, MichiganAges 18–42 - NCT07699562Recruiting
EMG device study in healthy people and ICU patients
This study tests a device that records muscle activity (EMG) in healthy volunteers and critically ill patients in the ICU. It aims to learn how well the device works in different groups, which could help monitor muscle function in the future.
Evanston, IllinoisAges 18–90 - NCT04989790Recruiting
Early mobility program for critically ill children in the PICU
This trial tests whether a structured “early mobility” activity plan (“PICU Up!”) helps children who are on a breathing machine recover or feel better while in the pediatric ICU. It aims to see if starting safe movement earlier makes a difference for critically ill kids.
Madera, CaliforniaAges Up to 18 years - NCT05218083Recruiting
Mobile rehab program with interval exercise after COVID-19
This trial tests a coach-supported, phone-based rehabilitation program that includes high-intensity interval-style exercise for people recovering from COVID-19 after a hospital stay. It may help improve breathing, strength, and walking by providing structured exercise at home.
Birmingham, AlabamaAges 18 years+ - NCT05629325RecruitingPhase 4
Buspirone for weak or missing esophagus contractions
This study tests whether buspirone helps people whose esophagus does not squeeze properly (or doesn’t squeeze at all), causing swallowing problems. You would be assigned to buspirone or a placebo and monitored to see if symptoms improve.
Leuven, Vlaams-BrabantAges 18 years+ - NCT05729061Recruiting
Testing movement with mobility assistive devices
This study measures how people move while using assistive devices during guided movement tasks, sometimes on a treadmill. It may help improve these tools and how safely they support different types of movement needs.
Edmonds, WashingtonAges 18–90 - NCT05865314Recruiting
Nutrition plus early therapy for adults in long ICU stays
This trial studies whether a planned nutrition plan, along with early physiotherapy (physical therapy), can improve outcomes for adults who expect to stay in the ICU for at least 7 days. It includes people who need feeding through a tube and/or special IV nutrition while on a breathing machine.
Geneva, Canton of GenevaAges 18 years+ - NCT05929027Recruiting
At-home gaming and exercise after stroke
This study tests whether an at-home program using gaming and hand exercises can improve arm and hand movement after a recent stroke. It may help you practice more comfortably at home with regular remote check-ins.
Baltimore, MarylandAges 21 years+ - NCT06059872Recruiting
Study of high-intensity interval training after stroke
This study tests whether a high-intensity interval training (HIIT) exercise program can help people with walking difficulties after a stroke. It looks for veterans who have had a stroke at least 6 months ago and walk slowly, to see if this type of exercise can improve their recovery.
Decatur, GeorgiaAges 18–89 - NCT06062303Recruiting
Capillary refill time to guide septic shock treatment
This trial tests a new way of giving fluids and medicines to people with septic shock. It focuses on a simple sign called capillary refill time (how fast color returns when you press a fingernail) to guide treatment, aiming to improve recovery.
ReimsAges 18 years+ - NCT06152302Recruiting
Water mobility test for infants with SMA
This study tests how well infants with spinal muscular atrophy (SMA) can move in water. The goal is to see if gentle water exercises can help with muscle weakness and overall development.
GarchesAges Up to 1 year
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Common questions
- Are there clinical trials for muscle atrophy or weakness?
- Yes. Clin2 currently lists 164 recruiting muscle atrophy or weakness studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a muscle atrophy or weakness trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a muscle atrophy or weakness trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.