Clinical trials
Muscle clinical trials
Below are recruiting muscle clinical trials, each written for real people, not researchers. We’re tracking 1,109 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05002556Recruiting
Bladder cancer follow-up registry for adults in France
This trial is a real-world registry that collects information during follow-up for certain early-stage bladder cancer. It may help doctors understand how urinary test results relate to recurrence and guide monitoring over time.
Aix-en-ProvenceAges 18 years+ - NCT04984473Recruiting
Breathing muscle training during heart rehab
This study tests whether breathing muscle training, added to regular heart rehab, can improve how well people with heart failure do day-to-day. It also compares results with healthy volunteers who do not have certain health problems.
Rochester, MinnesotaAges 18 years+ - NCT04800276Recruiting
Exercise program for leg artery disease
This trial tests a supervised exercise program for people with leg pain when walking caused by narrowed leg arteries. The goal is to see if exercise can improve walking ability and quality of life.
Le MansAges 18 years+ - NCT04752722RecruitingPhase 1/Phase 2
Gene therapy for bladder cancer that came back after BCG
This study tests a new gene therapy (EG-70) given directly into the bladder for people with a high-risk bladder cancer called NMIBC. It may be an option if BCG treatment stopped working, or if you cannot have or choose not to have bladder removal surgery.
Birmingham, AlabamaAges 18 years+ - NCT04067830RecruitingPhase 2
Breathing muscle training before lung surgery to prevent complications
This trial tests whether training your breathing muscles before lung surgery can reduce lung problems after surgery in people with stage I to IIIb lung cancer. It may help improve breathing and lower the chance of post-surgery lung complications.
Buffalo, New YorkAges 18 years+ - NCT03810768Recruiting
Metabolomics study of ICU-acquired weakness after surgery
This study looks at blood and body chemistry (called metabolomics) to understand and possibly predict muscle weakness that can happen in the ICU after surgery. It may help researchers find better ways to prevent or monitor this problem.
Vienna, State of ViennaAges 18 years+ - NCT03752034Recruiting
Muscle fragments after rotator cuff surgery to improve shoulder function
This study looks at whether using “muscle fiber fragments” during/after rotator cuff repair can help your shoulder work better. It targets people with a small tear in one shoulder who can follow the post-surgery follow-up plan.
Winston-Salem, North CarolinaAges 40–80 - NCT03589846Enrolling by invitation
Muscle stimulation during a sleep endoscopy test
This trial studies whether muscle stimulation during DISE (a procedure to look at your airway while you’re sedated) can help people with obstructive sleep apnea who can’t tolerate CPAP. Your DISE is part of routine care, and the study adds a muscle stimulation step to see if it changes what’s happening in the throat.
Nashvile, TennesseeAges 18 years+ - NCT03225677Recruiting
Testing a new scan to study muscle breakdown in cirrhosis
This study looks at how your body uses protein in your muscles when you have cirrhosis (a scarred liver). It uses a special “tracer” method (a substance that can be tracked) and may help researchers better understand muscle loss in people with milder cirrhosis.
Cleveland, OhioAges 18 years+ - NCT01953263RecruitingPhase 1/Phase 2
Muscle fragment treatment trial for urinary incontinence
This early-phase trial tests a treatment made from muscle fragments to improve urinary incontinence caused by weakness of the urethral “sphincter” (the valve that holds urine). It may help people with certain types of incontinence, but it also requires meeting several bladder and health criteria for safety.
Winston-Salem, North CarolinaAges 18–75 - NCT07855341RecruitingPhase 4
Nerve block study for hip replacement pain relief
This study tests two different amounts of a numbing medicine injected around the hip nerves before hip replacement surgery, to see if adding a steroid helps reduce pain after surgery. It aims to improve pain control and recovery.
Cairo, Cairo GovernorateAges 50–70 - NCT07625527RecruitingPhase 2
Stopping immunotherapy after bladder cancer disappears
This trial tests whether it's safe to stop immunotherapy once bladder cancer is no longer visible, instead of continuing it for a longer time. It aims to find out if stopping treatment early can reduce side effects while keeping the cancer from coming back.
TianjinAges 18 years+ - NCT07132788Recruiting
Study of pulmonary arterial hypertension and lean muscle mass
This study looks at how pulmonary arterial hypertension (PAH) affects lean muscle mass. It aims to understand the relationship between PAH and muscle loss, which could help improve treatments and quality of life.
Philadelphia, PennsylvaniaAges 18 years+ - NCT07597980Recruiting
Exercise and diet program to strengthen muscles in older adults
This study tests whether a lifestyle program combining exercise and nutrition can help adults over 50 improve their muscle strength and function. You'll work with researchers to see if this approach helps with mobility and overall health.
Baton Rouge, LouisianaAges 50 years+ - NCT04900558Recruiting
Study outcomes after robotic bladder removal surgery
This trial follows adults who are planning to have a robotic radical cystectomy (surgery to remove the bladder and surrounding tissue) to learn what outcomes to expect. If you choose to join and meet the basics, it may help your team compare results and improve care for future patients.
Florence, TuscanyAges 18 years+ - NCT05072600RecruitingPhase 2
Pembrolizumab after complete bladder cancer treatment response
This trial studies pembrolizumab (an immunotherapy) in people with muscle-invasive bladder cancer who had a combined “trimodality” treatment and then achieved a complete response. The goal is to help control the cancer after the initial treatment is finished.
Beijing, Beijing MunicipalityAges 18 years+ - NCT04620343Recruiting
Study of breathing treatment for EILO during exercise
This trial tests a treatment approach for exercise-related breathing difficulty called EILO. It aims to help people whose breathing problems show up during peak exercise and who want ongoing follow-up.
Bergen, VestlandAges 12 years+ - NCT05689775Recruiting
Robot-assisted reconstruction using tummy muscle flap after surgery
This trial studies a specific way to rebuild the pelvic floor (and sometimes the vagina) after major rectal or anal cancer surgery. It uses robotic surgery and a flap taken from your tummy muscle to help close and reconstruct the area.
OsloAges 18 years+ - NCT05680168Recruiting
Non-drug treatments for urinary leaks after prostate surgery
This trial studies whether applying an external magnetic treatment (magnetic stimulation), doing pelvic floor muscle exercises, or doing both together can reduce urinary leakage after radical prostatectomy. The goal is to find which approach works best for men recovering bladder control after prostate cancer surgery.
DohaAges 18–80 - NCT05716880RecruitingPhase 3
Keto-like diet supplements for muscle loss in nephrotic syndrome
This Phase 3 study tests a keto-like supplement (Ketosteril) to help prevent or slow muscle loss in people with nephrotic syndrome. It may help by improving nutrition when the kidneys are leaking large amounts of protein.
Warsaw, Masovian DistrictAges 18 years+ - NCT05887440Recruiting
Isokinetic strength training for knee control after stroke
This trial studies whether a special strength-training program that uses an “isokinetic” machine can improve walking and knee control in people after stroke. It is for people who have noticeable knee movement during walking and can safely take part in rehab.
RennesAges 18–75 - NCT03379909RecruitingPhase 2
Metformin taken by mouth for early bladder cancer
This trial studies whether a diabetes medicine called metformin can help prevent or control non-muscle-invasive bladder cancer inside the bladder. You would take it by mouth, and the study checks safety and whether it works.
Nijmegen, GelderlandAges 18 years+ - NCT05767762Recruiting
Tests whether leg muscle patterns predict treatment outcome in clubfoot
This study looks at how certain leg muscles move to see if that can predict how well an Achilles tenotomy (a small procedure to release tight tendon) works for children with idiopathic clubfoot. It may help doctors choose the best timing and approach for treatment.
NiceAges birth–1 year - NCT05825092RecruitingPhase 2
Early testosterone gel for people on breathing machines
This Phase 2 study tests whether starting testosterone gel soon after ICU admission can improve physical performance in critically ill adults who need a breathing machine for more than 48 hours. It’s also designed to check safety in this setting.
BordeauxAges 18–79
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Common questions
- Are there clinical trials for muscle?
- Yes. Clin2 currently lists 1,109 recruiting muscle studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a muscle trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a muscle trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.