Clinical trials
Muscle clinical trials
Below are recruiting muscle clinical trials, each written for real people, not researchers. We’re tracking 1,109 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05913882Recruiting
Breathing training for people with ALS to improve cough
This study tests a breathing and expiratory muscle training program to help people with ALS cough more effectively. It may help reduce breathing and airway trouble by strengthening the muscles used for cough in early-stage ALS.
Fort Lauderdale, FloridaAges 18–90 - NCT05926219Recruiting
Study C-protein changes with fatigue and aging
This study looks at how a blood protein called C-protein relates to fatigue and aging, and how exercise affects it. You may be able to join if you’re otherwise healthy and willing to do muscle testing and activity monitoring.
Eugene, OregonAges 18–80 - NCT05884138Recruiting
Amino acid supplement and exercise for people on dialysis
This trial studies whether taking essential amino acids along with exercise can improve muscle function in people receiving hemodialysis. It may help you build or maintain strength and mobility.
Daejeon, South KoreaAges 20–80 - NCT05903001Recruiting
Breathing muscle testing to help track lung disease
This study checks whether measurements of your breathing muscle (the diaphragm) can act as a useful “biomarker” to track lung disease. You might be asked to do breathing tests and follow study instructions, and your results may help researchers better monitor COPD, asthma, fibrosis, or pulmonary hypertension.
Aachen, North Rhine-WestphaliaAges 18 years+ - NCT05877846Recruiting
Personalized care to improve physical function in older adults
This study looks at precision (personalized) approaches to help older adults improve physical function. It may include giving a specific supplement depending on lab results, and it requires regular study visits and ability to complete procedures.
Chapel Hill, North CarolinaAges 65–85 - NCT05869734Enrolling by invitation
Conservative care to improve urinary symptoms and sleep in diabetes
This study looks at a non-surgical (“conservative”) approach to help women with diabetes who have bladder-related urinary symptoms and poor sleep. It aims to see whether these symptoms improve at the same time, helping quality of life.
New Taipei CityAges 20–79 - NCT05856136RecruitingPhase 4
Study how opioid exposure affects diaphragm muscle function
This study looks at whether receiving opioids for pain during lower-leg surgery changes how well the diaphragm muscle (the main breathing muscle) works afterward. It compares breathing muscle function in people who do and do not have certain lung conditions.
Rochester, MinnesotaAges 18 years+ - NCT05869812RecruitingPhase 2
HMB supplement study to help recovery after surgery
This trial tests whether taking an HMB supplement after surgery can help improve muscle size and function during recovery. It may be helpful if you are a female athlete planning rehab at a specific physical therapy clinic.
Overland Park, KansasAges 18–45 - NCT05851196Recruiting
Personalized exercise for recurrent low back pain
This study looks at how back muscle features can help tailor an exercise program for people with recurring, non-specific low back pain. It may help by matching exercises to your specific back function and symptoms.
DiepenbeekAges 18–60 - NCT05857150Recruiting
Study tests exercise effects in adults with obesity
This study looks at how your body responds to exercise if you have obesity. It may help researchers understand which changes happen with exercise and how safe it is for people in your age group.
Rochester, MinnesotaAges 20–45 - NCT05780177Recruiting
Brief behavioral therapy for insomnia in PTSD veterans
This trial tests a short, structured behavioral program to help improve sleep problems (insomnia) in veterans who also have posttraumatic stress disorder (PTSD). It may help you fall asleep easier and sleep more consistently while continuing your usual care when it’s stable.
San Francisco, CaliforniaAges 18–75 - NCT03042975Recruiting
Study brain and voice genetics in people with voice movement disorders
This study looks at how genetics and brain patterns are connected to laryngeal dystonia and voice tremor, including people with certain types of voice disorders. You may be asked to do imaging and voice-related assessments to help researchers understand what’s causing these symptoms.
Boston, MassachusettsAges Any age - NCT05801185Enrolling by invitation
Studying muscle changes after leg unloading in healthy young adults
This trial looks at how human muscle cells change when one leg is not used for a short time. It may help us understand muscle loss and how to prevent it.
Huddinge, Stockholm CountyAges 18–40 - NCT05754632Recruiting
Blood flow restriction exercises after ACL surgery in teens
This trial tests whether a special type of exercise that uses a cuff (blood flow restriction training, or BFRT) can help teens recover after ACL reconstruction. It’s designed to see if adding BFRT to standard rehab improves strength and return to sport.
Farmington, ConnecticutAges 12–18 - NCT05343286Recruiting
Personalized exercise plan for older adults
This study looks for health “signals” that can help tailor a physical activity program for people aged 60 and older. It may help decide which exercise approach works best for different individuals over time.
NiceAges 60 years+ - NCT05710848RecruitingPhase 1/Phase 2
Study drug for repeat bladder tumor surgery patients
This trial tests STM-416, given around the time you have surgery to remove recurring bladder tumors, to see if it can reduce the chance the cancer comes back. It is for people with high-risk early bladder cancer (non–muscle-invasive) who have already had standard treatment and now need another TURBT.
Mesa, ArizonaAges 18 years+ - NCT05745298Recruiting
Electrical and breathing therapy to improve unassisted cough after spinal injury
This study tests whether pairing electrical stimulation with breathing muscle training can help you cough without needing assistance. It’s for people recovering from a spinal cord injury within the last year, and who can safely feel and respond to the electrical stimulation.
Miami, FloridaAges 18 years+ - NCT05725928Recruiting
Walking-support program for older hospitalized patients
This study tests whether extra help and guidance to walk while you’re in the hospital can improve health and recovery. It’s for older adults who can safely do some walking after being admitted for a medical problem.
Springfield, MassachusettsAges 65 years+ - NCT04416191Recruiting
Immune cells study during inactivity and recovery
This study looks at how your immune system changes when you are inactive and then become more active again. It may help researchers understand how recovery affects immune health after disuse.
Salt Lake City, UtahAges 18–85 - NCT04882904Recruiting
Tracking movement in people with ALS and healthy volunteers
This study continuously measures activity and movement in people with ALS and in control participants. It aims to better understand how muscle disease changes day-to-day function, which may help improve future monitoring or care.
Liège, LiègeAges 18 years+ - NCT05706129RecruitingPhase 1/Phase 2
Testing targeted imaging and therapy for advanced solid tumors
This early-phase study tests two radioactive medicines that first help doctors see tumors and, in some parts of the study, treat them. It may help people with advanced, hard-to-remove cancers that have a specific tumor marker (CA IX).
MelbourneAges 18 years+ - NCT05684562Recruiting
Lung function and exercise capacity in Fontan patients
This study looks at how well the lungs and heart work together during exercise in people who have had the Fontan operation. The goal is to understand how lung function affects overall fitness, which can help improve care for Fontan patients.
AnkaraAges 8–55 - NCT05700825RecruitingPhase 2
Rehab training to improve swallow safety in Parkinson’s
This trial tests a rehabilitation approach aimed at improving airway protection during swallowing in people with Parkinson’s disease. It may help reduce the risk of food or liquid going down the wrong way by improving swallow safety.
West Lafayette, IndianaAges 50–90 - NCT05708885Recruiting
Testing a tool to change esophagus muscle movement
This study looks at how a device affects how the esophagus muscles squeeze and relax. It may help people better understand swallowing problems, even if their usual esophagus test looks normal.
Milwaukee, WisconsinAges 18–90
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Common questions
- Are there clinical trials for muscle?
- Yes. Clin2 currently lists 1,109 recruiting muscle studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a muscle trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a muscle trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.