Clinical trials
Neoadjuvant clinical trials
Below are recruiting neoadjuvant clinical trials, each written for real people, not researchers. We’re tracking 903 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07651358Recruiting
Web Program to Help Pancreatic Cancer Patients Exercise and Eat Better
This study tests a personalized website program called COMPASS designed to help people with stage I-III pancreatic cancer improve their exercise and diet while receiving chemotherapy before surgery. The goal is to see if this program helps patients feel better and stay stronger during treatment.
Portland, OregonAges 18 years+ - NCT07653503RecruitingPhase 1
Lymph node immunotherapy before cervical cancer surgery
This trial tests whether giving an immunotherapy drug (nivolumab) directly into lymph nodes before standard surgery can help treat cervical cancer. It is for patients who have not had prior immunotherapy treatments.
GroningenAges 18 years+ - NCT07667751RecruitingPhase 2
Study of Ipalotinib with Sunitinib and Olaparib before surgery for advanced ovarian cancer
This trial tests a combination of three drugs (Ipalotinib, Sunitinib, and Olaparib) given before surgery to shrink tumors in people with a specific type of advanced ovarian cancer that has a genetic marker called HRD-positive. The goal is to see if this treatment helps make surgery more effective.
HefeiAges 18–75 - NCT07618624Enrolling by invitationPhase 2
Drug combination before surgery for recurrent head and neck cancer
This trial tests three drugs (finotonlimab, cetuximab, and docetaxel) given before surgery to remove recurrent head and neck cancer in patients whose cancer stopped responding to previous immunotherapy. The goal is to shrink the tumor and improve surgical outcomes.
Foshan, GuangdongAges 18–75 - NCT07550972Enrolling by invitationPhase 2
Combination drug treatment before surgery for advanced head and neck cancer
This study tests two drugs (pertuzumab and lenvatinib) given together before surgery for advanced head and neck squamous cell carcinoma. The goal is to shrink the tumor and improve outcomes for patients who haven't received prior cancer treatment.
Hangzhou, ZhejiangAges 18–75 - NCT07465497Enrolling by invitation
Preventing Chemo Brain with Prebiotics and Synbiotics
This trial tests whether taking a special blend of prebiotics and synbiotics (friendly bacteria and food for them) can help prevent or reduce memory and thinking problems that sometimes happen during chemotherapy for breast cancer.
Zapopan, JaliscoAges 18 years+ - NCT07353294Enrolling by invitationPhase 1
Propranolol plus immunotherapy and chemo before bladder cancer surgery
This trial tests adding a blood pressure medication (propranolol) to a combination of immunotherapy (tislelizumab) and chemotherapy before surgery for bladder cancer that has spread to lymph nodes. It aims to see if this can help shrink the tumor before it is removed.
Guangzhou, GuangdongAges 18 years+ - NCT07312578Enrolling by invitationPhase 2
Targeted drugs plus chemo before surgery for esophageal cancer
This trial tests a combination of two targeted drugs (nimotuzumab and camrelizumab) plus standard chemotherapy before surgery for people with esophageal squamous cell carcinoma. The goal is to see if this approach helps shrink the tumor and improve outcomes.
Beijing, Beijing MunicipalityAges 18–70 - NCT07107815Enrolling by invitation
Predicting rectal cancer treatment response using MRI
This study uses advanced MRI scanning and computer analysis to predict how well rectal cancer might respond to treatments given before surgery. It may help doctors choose the best approach for you.
Beijing, Beijing MunicipalityAges Any age - NCT06863831Enrolling by invitation
Comparing YSQTG to placebo with standard treatment for esophageal cancer
This trial tests whether adding an herbal granule (YSQTG) to standard chemotherapy with or without immunotherapy helps patients with a specific type of advanced esophageal cancer. It focuses on people whose cancer is stage III to IVa and who have not had treatment yet.
Beijing, ChaoyangAges 18–80 - NCT06714084Enrolling by invitation
Treating high-risk cervical cancer with chemoradiation and immunotherapy
This trial tests a new drug called Cardenimumab combined with standard chemotherapy and radiation for women with high-risk cervical cancer. The goal is to see if adding this drug can improve outcomes for patients whose tumors are large, have spread to lymph nodes, or are stage IV.
Wuhan, HubeiAges 18–75 - NCT06650748Enrolling by invitationPhase 2
A study of hormone therapy with or without a targeted drug for breast cancer
This trial tests if adding a targeted drug (CDK4/6 inhibitor) to hormone therapy works better than hormone therapy alone for women with a certain type of breast cancer (HR+/HER2-). The study measures the activity of tumor cells (Ki-67) to help decide treatment.
BeijingAges 18–70 - NCT06510127Enrolling by invitation
AI Predicts Chemo Effectiveness Before Breast Surgery
This study uses an AI model to predict how well chemotherapy will work before breast cancer surgery. It looks back at medical records and images from women who have already completed treatment to see if the AI can help guide future care.
Guangzhou, GuangdongAges Any age - NCT06303583Enrolling by invitationPhase 1/Phase 2
Chemo-radiation followed by immunotherapy for esophageal cancer
This trial tests if giving chemotherapy and radiation before surgery, followed by immunotherapy, can improve outcomes for people with a specific type of esophageal cancer that can be surgically removed.
Hangzhou, ZhejiangAges 18–75 - NCT05171335Enrolling by invitationPhase 2
Lenvatinib plus TACE before transplant for large liver cancer
This trial tests whether taking lenvatinib (a targeted pill) before a liver procedure called TACE can help people with large hepatocellular carcinoma (HCC) get better results while waiting for a liver transplant. It may help shrink or control the cancer without stopping transplant plans.
Houston, TexasAges 18 years+
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Common questions
- Are there clinical trials for neoadjuvant?
- Yes. Clin2 currently lists 903 recruiting neoadjuvant studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a neoadjuvant trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a neoadjuvant trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.