Clinical trials
Oral Cancer clinical trials
Below are recruiting oral cancer clinical trials, each written for real people, not researchers. We’re tracking 281 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07001709RecruitingPhase 4
How abiraterone affects oxycodone in prostate cancer
This study looks at how a common prostate cancer drug (abiraterone) affects how the body processes a painkiller (oxycodone). Men with prostate cancer who take abiraterone will be compared with those who do not, to see if the painkiller works differently.
Deventer, OverijsselAges 18 years+ - NCT05562375Recruiting
Testing a device to detect early mouth pre-cancer changes
This study checks whether a handheld device (GOCCLES®) can spot early mouth “pre-cancer” changes by looking at suspicious areas in the mouth. If it works, it could help doctors find these problems earlier and guide next steps.
Alcorcón, MadridAges 18 years+ - NCT07110142Recruiting
Tongue strength exercises after tongue cancer surgery
This study tests a tongue strengthening exercise program for people who have had partial tongue removal and reconstruction. The goal is to see if these exercises can help you regain better tongue function and speech after surgery.
Cleveland, OhioAges 18 years+ - NCT04214990RecruitingPhase 3
Aspirin after early stomach precancer or early cancer removal
This trial tests whether taking aspirin after endoscopic removal of an early stomach condition can lower the chance of the cancer coming back or progressing. You may be considered if your early stomach findings were fully removed and you’re able to avoid certain medications that raise bleeding risk.
BusanAges 19–70 - NCT07293013Recruiting
Olive oil mouthwash for mouth sores during cancer treatment
This study tests whether using an olive oil mouthwash can help prevent or reduce mouth sores caused by radiation and chemotherapy for head and neck cancer. If you are starting treatment, you may be able to join and receive the mouthwash to see if it helps keep your mouth healthier.
Chiayi City, Chia-Yi CityAges 20 years+ - NCT07095023Recruiting
Oral chemo and targeted therapy before breast cancer surgery
This trial tests a combination of an oral chemotherapy pill (paclitaxel) with two targeted antibodies (pertuzumab and trastuzumab) given before surgery for HER2-positive breast cancer. The goal is to shrink the tumor and make surgery more effective.
Beijing, Beijing MunicipalityAges 18–75 - NCT03545256Recruiting
Outpatient surgery to map lymph nodes in mouth and throat cancer
This trial studies a planned, same-day (outpatient) surgery approach to find and check cancer spread to nearby lymph nodes in early-stage mouth and throat squamous cell cancer. It may help doctors remove the right lymph nodes and decide on any needed further treatment.
Montpellier, HéraultAges 18 years+ - NCT06631092RecruitingPhase 1/Phase 2
Personalized cancer vaccine with standard therapy for triple-negative breast cancer
This trial tests a personalized cancer vaccine (NECVAX-NEO1) given along with standard chemotherapy and immunotherapy before surgery for patients with triple-negative breast cancer. The vaccine is customized to target specific mutations in your tumor, aiming to boost your immune system and improve treatment outcomes.
ErlangenAges 18 years+ - NCT07717307Recruiting
Comparing two neck surgeries for oral cancer spread
This trial tests whether a smaller neck surgery works as well as a larger one for people with oral cancer that has spread to one lymph node. The goal is to see if less extensive surgery can reduce side effects while still controlling the cancer.
Kolhāpur, MaharashtraAges 21–75 - NCT07726199Recruiting
Neck treatment approaches for oral cancer without neck spread
This study compares different ways to treat the neck in patients with early-stage oral cancer that hasn't spread to the neck. The goal is to find which approach works best while keeping side effects low.
Kolhāpur, MaharashtraAges 21–75 - NCT05990192RecruitingPhase 2
SBRT with or without niraparib for ovarian cancer after PARP inhibitor treatment
This trial tests a new treatment approach for people with ovarian cancer that has started to progress in a few spots (up to 3) after taking a PARP inhibitor. It combines targeted radiation (SBRT) to those spots, followed by another PARP inhibitor (niraparib), to see if this can control the cancer further.
Leeds, LeedsAges 18 years+ - NCT06027242Recruiting
Glutamine supplement after stomach cancer surgery
This trial tests if taking glutamine (a nutrient) as an oral supplement helps patients recover after surgery to remove stomach cancer. It aims to see if it improves healing and quality of life.
TaipeiAges 20 years+ - NCT05973656Recruiting
Study how alcohol affects the risk of mouth cancer
This study looks at how a breakdown product from alcohol (acetaldehyde) may play a role in oral (mouth) cancer. It may help researchers understand who is more affected by alcohol and why.
Minneapolis, MinnesotaAges 18–45 - NCT05191680RecruitingPhase 2
Testing apalutamide in early prostate cancer active surveillance
This Phase 2 trial tests whether apalutamide can help people with early prostate cancer who choose active surveillance. It uses MRI and biopsy results to confirm the cancer type and location, then checks if treatment is safe and potentially helpful.
Cambridge, CambridgeshireAges 18 years+ - NCT06008275RecruitingEarly Phase 1
Neratinib and ruxolitinib for metastatic triple-negative breast cancer
This early-phase trial tests a combination of two targeted drugs, neratinib and ruxolitinib, for people with metastatic triple-negative breast cancer who have already had standard chemotherapy. The goal is to see if the combination is safe and effective.
Dallas, TexasAges 18 years+ - NCT06535867Recruiting
Comparing phone-based vs. in-person mouth cancer screening in rural India
This study compares two ways to find early signs of mouth cancer or conditions that could lead to cancer. One method uses a simple phone-based health check, and the other uses standard in-person screening. People in rural areas of Varanasi who are at risk—such as those who use tobacco or have mouth sores—may be able to join.
New York, New YorkAges 18 years+ - NCT05853692Recruiting
Preventing mouth sores during head and neck radiation
This trial tests a gel called “Gel X” to help prevent painful mouth sores (oral mucositis) in people receiving radiation for head and neck cancer. It may help you stay more comfortable and maintain eating and speaking during treatment.
Roma, ItalyAges 18 years+ - NCT06706752Recruiting
Shengbai oral formula for chemotherapy side effects
This study tests if a Chinese herbal formula called Shengbai can safely reduce side effects from chemotherapy. It might help you feel better during cancer treatment.
Oakland, CaliforniaAges 18–80 - NCT03903835RecruitingPhase 3
Biomarker-guided treatment for metastatic prostate cancer
This Phase 3 trial tests a prostate cancer treatment plan chosen using your tumor’s biomarker results. It aims to improve outcomes for men with metastatic prostate cancer starting first systemic treatment.
AalstAges 18 years+ - NCT05030597Recruiting
PET scans targeting FAP for oral cancer and recurrence
This trial uses a special PET scan that targets a substance called FAP to better find oral squamous cell cancer and check for recurrence. It may help doctors see where cancer activity is and guide treatment planning, especially around surgery and (for some people) neoadjuvant therapy before surgery.
Wuhan, HubeiAges 18–70 - NCT06148038RecruitingPhase 1
CBD oil for breast cancer before surgery
This trial tests if taking CBD oil before surgery can help treat invasive breast cancer. It is for women with fast-growing tumors who are scheduled for surgery.
Charleston, South CarolinaAges 18 years+ - NCT06354712RecruitingPhase 2
Can N-acetylcysteine prevent mouth sores during radiation?
This study tests whether a medicine called N-acetylcysteine (NAC) can prevent mouth sores caused by radiation therapy for head and neck cancer. If you are starting radiation, this trial may help protect your mouth from painful side effects.
Al MansurahAges 18–80 - NCT03245411Recruiting
Helps cancer patients take oral medicines as prescribed
This study tests a set of practical support steps to help people with advanced cancer take their oral (by mouth) treatment medicines correctly. It may help improve adherence and reduce missed doses or appointments.
Philadelphia, PennsylvaniaAges 18 years+ - NCT07217938RecruitingPhase 2
Testing statins for swallowing problems after radiation
This study tests whether a common cholesterol-lowering drug (pravastatin, a type of statin) can reduce swallowing problems caused by past radiation for head and neck cancer. If you have had radiation at least 2 years ago and still have trouble swallowing, this trial may help find a new way to ease those symptoms.
Melbourne, VictoriaAges 18 years+
Hear when a new Oral Cancer trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for oral cancer?
- Yes. Clin2 currently lists 281 recruiting oral cancer studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a oral cancer trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a oral cancer trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.