Clinical trials
Regurgitation clinical trials
Below are recruiting regurgitation clinical trials, each written for real people, not researchers. We’re tracking 200 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07086534Recruiting
GeminiOne Clip for Severe Mitral Regurgitation
This trial tests a new device called GeminiOne that clips together part of your leaky mitral valve to reduce backward blood flow. It is for people with severe mitral regurgitation who are not candidates for open-heart surgery.
Thousand Oaks, CaliforniaAges 18 years+ - NCT04797572Recruiting
Testing a tool to measure the aortic valve during surgery
This trial evaluates a measuring tool used during aortic valve surgery. It may help surgeons size the valve opening more accurately when treating valve leakage or a dilated (enlarged) ascending aorta.
BrusselsAges 18–80 - NCT07075861Recruiting
A study of a new heart valve for people too sick for surgery
This study is testing a new valve device (JenaValve Trilogy) that can be placed without open-heart surgery. It may be an option for people whose heart team says regular valve replacement surgery is too risky.
San Donato Milanese, MilanoAges 18 years+ - NCT06668389RecruitingPhase 4
Testing a diabetes medicine for repaired tetralogy of Fallot
This study tests a type of diabetes medicine (SGLT2 inhibitor) to see if it can help people who had surgery for tetralogy of Fallot feel better and have stronger heart and lung function. It may be a good fit if you are an adult with repaired tetralogy of Fallot and do not have certain other health problems.
Hong KongAges 18 years+ - NCT07057466Recruiting
Checking heart scans with artificial intelligence
This study uses AI to read electrocardiograms (heart rhythm tests) to see if they can detect certain heart structure problems earlier. If you are already scheduled for an echocardiogram (heart ultrasound), your data may be used to help improve detection.
BristolAges 18–90 - NCT07055919Recruiting
Assist system for mitral valve clip procedure
This study is testing a new assist system to help doctors perform a minimally invasive procedure (MitraClip) that clips the leaky mitral valve without open-heart surgery. It is for people with severe mitral regurgitation who cannot safely have surgery or choose not to.
Xiamen, FujianAges 18 years+ - NCT07045753Recruiting
Mitral valve repair registry study
This study is gathering information from people getting a less invasive procedure called M-TEER to fix a leaky mitral valve. Joining helps doctors learn more about how this treatment works in real life.
Bad Segeberg, Schleswig-HolsteinAges 18–100 - NCT07021612Recruiting
Registry study of TAVI for severe aortic regurgitation
This study is for people with a severe leaking aortic valve (aortic regurgitation) who are too high-risk for open-heart surgery. It tracks how well a less-invasive valve replacement (TAVI) using the JenaValve or J-Valve works for them.
Hong Kong, ShatinAges 18 years+ - NCT07007143RecruitingPhase 4
Blood thinner study after heart valve repair
This trial tests different blood-thinning medicines after a mitral valve repair procedure (TEER) in people who do not need long-term blood thinners. It aims to find the safest and most effective strategy to prevent blood clots.
Beijing, Beijing MunicipalityAges Any age - NCT06954792Enrolling by invitation
Studying heart changes after tricuspid valve replacement
This study looks at how the heart adjusts after a procedure to replace the tricuspid valve (the valve between the right upper and lower heart chambers). It focuses on patients who need medication to support their blood pressure within 24 hours after the procedure, to better understand and manage this unstable period.
New York, New YorkAges 18 years+ - NCT06951672Recruiting
Testing a new mitral valve repair device
This trial tests a new device called AMEND™ that is placed through a vein in the leg to repair a leaky mitral valve without open-heart surgery. It is for people with significant mitral regurgitation who are at high risk for surgery.
Phoenix, ArizonaAges 21 years+ - NCT06920745Recruiting
TriClip study for severe tricuspid regurgitation
This study is testing whether the TriClip device helps people with severe tricuspid regurgitation (a leaky heart valve) feel better. It compares people who received the TriClip to those who didn't get the procedure.
Santa Clara, CaliforniaAges 18 years+ - NCT06917586Recruiting
Mosaic mitral valve study for patients under 65
This study looks at long-term results in people under 65 who received a specific type of replacement heart valve (the Mosaic mitral valve) during surgery at ProMedica Toledo Hospital. It aims to understand how well the valve works over time.
Toledo, OhioAges 18–65 - NCT06906926Recruiting
Studying the Harmony heart valve for long-term safety
This study is following people who get the Harmony valve to see how well it works over time. The valve helps blood flow from the heart to the lungs in people with certain heart conditions.
CopenhagenAges Any age - NCT06901466RecruitingPhase 4
Blood thinner study after heart valve repair
This study tests different ways to use blood thinners after a minimally invasive heart valve repair procedure. It may help patients who need long-term blood thinning to prevent clots or stroke.
Beijing, Beijing MunicipalityAges Any age - NCT06869954Recruiting
Bicuspid aortic valve repair: comparing two surgical techniques
This trial tests two different ways to repair a leaky bicuspid aortic valve (a valve with two flaps instead of three). The goal is to see which repair method works better. If you need surgery for a severely leaking valve and your valve is the right shape, you may be able to join.
Augsburg, BavariaAges 18 years+ - NCT06833476Recruiting
EVOQUE device trial for severe tricuspid regurgitation
This study looks at how well the EVOQUE device works for people with Medicare who have severe tricuspid regurgitation (a leaky heart valve) or who might get the device. It helps doctors learn more about treating this condition.
Irvine, CaliforniaAges 65 years+ - NCT06797687Recruiting
Studying the mitral valve with different scans before surgery
This study looks at how well CT scans and 3D echo (ultrasound) measure the mitral valve ring before surgery for severe mitral valve leakage. It may help doctors better plan valve repair.
RomaAges 18 years+ - NCT06770062Recruiting
How the heart changes after mitral valve repair surgery
This study at Mayo Clinic uses MRI and other tests to see how the heart's main pumping chamber changes shape after robot-assisted mitral valve repair surgery for severe mitral regurgitation. It may help doctors better understand how patients recover.
Rochester, MinnesotaAges 18 years+ - NCT06714500Recruiting
New valve for severe tricuspid leak in high-risk patients
This trial tests a new device called the Lux-Valve Plus to replace the tricuspid valve without open-heart surgery. It may help people who have severe leaking of the tricuspid valve and are too high-risk for surgery or not eligible for other non-surgical treatments.
Hong Kong, ShatinAges 50–90 - NCT06663566Enrolling by invitation
FAPI imaging for right heart function in tricuspid valve leak
This trial uses a special type of PET scan called FAPI to look at how well the right side of your heart is working when you have a leaky tricuspid valve. It may help doctors better understand and manage right heart strain caused by too much blood flow.
Beijing, Beijing MunicipalityAges 18–90 - NCT06648577Recruiting
3D ultrasound heart muscle wave measurements
This study uses 3D ultrasound to measure mechanical waves in the heart muscle of people with different severities of mitral regurgitation (a leaky heart valve). It aims to better understand how the heart adapts to the leak, which could help guide treatment decisions.
Paris, ParisAges 18 years+ - NCT06611579Recruiting
Study of the MonarQ System for Leaky Tricuspid Valve
This study tests a new device called the MonarQ TTVR System, which is placed through a small tube in a blood vessel to fix a leaky tricuspid valve without open-heart surgery. It is for people with severe tricuspid regurgitation symptoms that are not relieved by heart failure medicines alone.
Los Angeles, CaliforniaAges 18 years+ - NCT06600191Recruiting
New mitral valve study for leak repair
This trial tests a new device called the Capstan system to fix a leaky mitral valve (mitral regurgitation) without open-heart surgery. It may help people whose valve leak is moderate to severe and still have symptoms despite medicines.
MelbourneAges 18 years+
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Common questions
- Are there clinical trials for regurgitation?
- Yes. Clin2 currently lists 200 recruiting regurgitation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a regurgitation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a regurgitation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.