Clinical trials
Spine clinical trials
Below are recruiting spine clinical trials, each written for real people, not researchers. We’re tracking 254 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07290361Recruiting
Physical therapy for spine pain in primary care
This trial tests a program that connects people with spine pain (neck or back pain) from their primary care clinic to a physical therapist. The goal is to see if this approach helps patients get more timely and effective care.
San Diego, CaliforniaAges 18 years+ - NCT07225101RecruitingPhase 4
Testing STRATAFIX stitches for brain and spine surgery
This trial tests a special type of stitch (called STRATAFIX) for closing wounds after brain or spine surgery. It may help the wound heal better and reduce complications.
Lansing, MichiganAges 18 years+ - NCT07180940RecruitingPhase 4
Comparing two medicines added to a nerve block for back surgery
This study compares two medicines (dexamethasone and dexmedetomidine) added to a nerve block for pain control during and after lower back surgery. It aims to see which one works better for reducing pain and the need for other painkillers.
PoznanAges 18 years+ - NCT05452694Recruiting
Personalized pain relief after back fusion surgery
This trial tests a personalized plan to manage pain after lumbar (lower back) fusion and decompression surgery. It may help reduce difficult pain while guiding safe use of opioids around the time of surgery.
Pittsburgh, PennsylvaniaAges 18–99 - NCT06140927RecruitingPhase 3
Ketamine's effect on spinal monitoring during back surgery
This study tests if giving ketamine during certain back surgeries affects how well doctors can monitor your spinal nerves during the operation. It's for adults having a posterior spinal fusion.
San Francisco, CaliforniaAges 18–100 - NCT05817747Recruiting
Using big data to predict outcomes after spine surgery
This study collects information from people having surgery for problems in the lower (lumbar) or neck (cervical) spine. It tests whether using “big data” from routine care can help predict surgical outcomes and improve future decisions.
Ängelholm, Skåne CountyAges 18 years+ - NCT07039968RecruitingPhase 2
Standard vs. high dose radiation for spine cancer spread
This trial compares standard and higher doses of focused radiation (stereotactic radiosurgery) to treat cancer that has spread to the spine. It aims to find if a higher dose works better while keeping side effects manageable.
TaipeiAges 18 years+ - NCT07017985Recruiting
Diabetes in patients having first lower back surgery
This study looks at how common diabetes is in people about to have their first lower back surgery (lumbar spine surgery). It aims to help doctors better understand the link between diabetes and spine health.
MassyAges 18 years+ - NCT06971835Enrolling by invitation
NanoParticle Matrix spine surgery registry
This study follows people who receive a special bone graft material called NanoParticle Matrix (NPM) during spine surgery. Researchers want to track outcomes over two years to see how well it works.
Baton Rouge, LouisianaAges 18 years+ - NCT06867809Recruiting
Spinal and brain stimulation for arm movement after neck injury
This study tests whether using a combination of spinal and brain stimulation can help improve arm and hand movement in people who have had a cervical spinal cord injury (neck area) at least one year ago. It is for those with some remaining movement but not full strength.
New York, New YorkAges 18 years+ - NCT06083298Recruiting
Nerve blocks for pain after cervical spine surgery
This trial tests two types of nerve blocks to see which works better for pain after back-of-the-neck surgery. It aims to help patients have less pain and use less opioid medicine.
Zagazig, AlsharqiaAges 21–60 - NCT06716294Recruiting
Radiofrequency ablation and stabilization for spine tumors
This trial tests a treatment that uses heat to destroy active spine tumors from cancer that has spread, followed by stabilizing the bone. It aims to see if the treatment works by using a special scan (PET-CT) to confirm the results.
Athens, AthensAges 18–90 - NCT05996133RecruitingPhase 4
Neck Numbing Shot vs. Sham for Neck Surgery Pain
This trial tests whether a numbing injection (called a multifidus cervicis plane block) in the neck muscles helps reduce pain after back-of-the-neck fusion surgery. Half the participants will get the real block, the other half a sham (fake) block, to see if it really works.
Hartford, ConnecticutAges 40–80 - NCT03707288Recruiting
Exercise study for neck and low back pain in medical students
This study looks at neck and low back pain in medical students and asks participants to follow a set exercise plan for a period of time. It may help researchers understand what kind of exercise support could improve symptoms in students.
Kingston, KingstonAges Any age - NCT06462729RecruitingPhase 1/Phase 2
Testing a new bone graft for lower back fusion surgery
This trial tests a new bone graft material called LDGraft for people who need a single-level lower back fusion (anterior lumbar interbody fusion). It aims to see if the new graft is as good as or better than current options for helping bones heal together.
Fort Wayne, IndianaAges 22–80 - NCT06450834Enrolling by invitation
Ostene in planned open back spine surgery
This trial tests an experimental bone healing material, Ostene, during spine surgery. It may help reduce scar tissue and improve fusion. You are likely eligible if you are having planned open back surgery for nerve decompression and fusion.
Baltimore, MarylandAges 18–88 - NCT06439953Recruiting
Irrigation solution for spinal surgery instrumentation
This trial tests a solution used to clean the surgical site during spine surgeries to see if it helps prevent infections. It is for patients having certain types of spine surgery for conditions like deformity, cancer, or trauma.
Providence, Rhode IslandAges 18 years+ - NCT06383962Recruiting
Synergy Disc cervical disc replacement outcomes study
This trial is for people who are getting or have already received a Synergy Disc implant to replace a damaged disc in the neck. It follows patients over time to see how well the disc performs in relieving nerve pain or spinal cord compression.
BirminghamAges 21 years+ - NCT06030570Recruiting
Spine rehab program: how well does it work?
This trial tests a spine rehabilitation program that combines different types of care (like physical therapy and counseling) for adults with spine problems that haven't gotten better on their own. It aims to see if this program helps improve function and quality of life.
LeuvenAges 18 years+ - NCT06267248Enrolling by invitation
3D scanning to guide spine surgery
This trial tests a 3D scanner that maps your spine during surgery to help the surgeon work more accurately. It is for people already planning spine surgery where the back bones are exposed.
Boston, MassachusettsAges 18–80 - NCT06226272Recruiting
Study of Stryker spine device results
This trial is checking how well a Stryker spine device works in people who need spine surgery. Eligibility depends on the specific device and is decided by the study doctors.
Jacksonville, FloridaAges 18 years+ - NCT06204315RecruitingPhase 2
Spine radiosurgery for spinal cord compression
This trial tests a precise radiation technique for people whose spinal tumors are very close to the spinal cord or nerves. It aims to safely give higher radiation doses while limiting damage to the cord.
Houston, TexasAges 18 years+ - NCT05691062Enrolling by invitationPhase 4
Titanium versus PEEK for one-level back fusion
This trial compares two different implanted materials (titanium vs. PEEK) used in a one-level spinal fusion for people with lumbar stenosis and spondylolisthesis. It’s meant to see which device performs better after surgery for pain and leg symptoms when non-surgical treatments haven’t helped.
Minneapolis, MinnesotaAges 18–70 - NCT05367609Recruiting
Personalized pain plan for kids getting spine fusion surgery
This trial tests a personalized plan to manage pain around the time of pediatric posterior-lateral spinal fusion surgery. It aims to improve comfort and reduce the chance of pain or opioid problems after surgery by tailoring pain medicines to the child.
San Francisco, CaliforniaAges 10–21
Hear when a new Spine trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for spine?
- Yes. Clin2 currently lists 254 recruiting spine studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a spine trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a spine trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.