Clinical trials
Statin clinical trials
Below are recruiting statin clinical trials, each written for real people, not researchers. We’re tracking 81 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06738758Recruiting
Early intensive cholesterol-lowering study for acute coronary syndrome
This study tests whether starting strong cholesterol-lowering treatment early in the hospital can improve outcomes for people with acute coronary syndrome (a serious heart condition like a heart attack or unstable angina). It may help if you have high LDL cholesterol.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05062239Recruiting
Statin use after valve surgery to prevent heart rhythm trouble
This study looks at whether taking statin medicines around the time of surgical aortic valve replacement can lower the chance of a common post-surgery heart rhythm problem called atrial fibrillation. It also compares statin-related factors in people who are at the time of surgery in normal rhythm and not on strong rhythm-stabilizing medicines.
OdenseAges 60–95 - NCT06102863RecruitingPhase 2
Progesterone and statins for young women with early endometrial cancer or atypical hyperplasia
This trial tests whether adding a statin to progesterone therapy helps young women with early endometrial cancer or atypical endometrial hyperplasia who want to preserve their fertility. It aims to find a better treatment option for those who may not respond well to progesterone alone.
Beijing, Beijing MunicipalityAges 17–45 - NCT07098975RecruitingPhase 2
Statin for severe early-onset placental insufficiency
This trial tests if taking pravastatin (a statin) can improve blood flow to the placenta in pregnant people with either severe early-onset preeclampsia (high blood pressure) or a baby not growing well. The goal is to help the pregnancy last longer and improve outcomes.
BarcelonaAges 18 years+ - NCT07036991Recruiting
Comparing two treatments for narrowed neck arteries
This trial tests whether adding a PCSK9 inhibitor to a statin is better than a statin alone for people with mild-to-moderate narrowing of the carotid artery (the main artery in the neck). It looks at how well these treatments slow plaque buildup and prevent strokes.
ShanghaiAges 18 years+ - NCT06722521RecruitingPhase 4
Comparing two treatments for high coronary calcium without symptoms
This trial compares a combo of statin and ezetimibe without aspirin against statin alone with aspirin in people with high coronary calcium but no blocked arteries. It aims to find which approach is safer and more effective without causing bleeding risk.
SeoulAges 19 years+ - NCT06684106Recruiting
Can a liver medicine protect your blood sugar while on statins?
This study tests if a medicine called ursodeoxycholic acid can help prevent blood sugar rises that statins sometimes cause. It is for people with high cholesterol who have not yet taken a statin, to see if adding this medicine keeps their blood sugar healthy.
Xi'an, ShaanxiAges 18–75 - NCT06603363Recruiting
Statin effects on heart artery plaques seen on CT scans
This trial studies how short-term statin therapy changes plaque buildup in heart arteries. It uses CT scans to see if statins can make plaques more stable and reduce heart risks.
Budapest, BudapestAges 45–75 - NCT03936361RecruitingPhase 3
Statins after a stroke bleed in the brain (Phase 3)
This trial studies whether continuing or stopping statin medicine after a spontaneous bleeding stroke in the brain (called lobar ICH) leads to better outcomes. It may help clarify if statins are safer to stay on—or better to pause—after this type of event.
Boston, MassachusettsAges 50 years+ - NCT04087200Recruiting
High-dose statin early after heart attack to protect kidneys
This trial looks at whether starting a high dose of a statin (cholesterol medicine) right away after an acute coronary syndrome (a serious heart condition) can reduce future heart and kidney problems. It may help patients by testing a strategy meant to prevent complications soon after the event.
PratoAges Any age - NCT04601116RecruitingPhase 3
Atorvastatin for hormone-positive breast cancer to prevent recurrence
This Phase 3 study tests whether taking atorvastatin (a cholesterol-lowering medicine) can improve outcomes for women with estrogen-receptor–positive breast cancer. It may help by affecting cancer-related pathways and reducing risk of recurrence or progression.
AarhusAges 18 years+ - NCT04847752Recruiting
Predicting outcomes after stroke from artery plaque
This study looks at factors that can help predict recovery and risk after an ischemic stroke caused by plaque buildup in a major artery. It may help doctors better forecast prognosis and tailor follow-up care for people like you.
WuhanAges Up to 80 years - NCT07824323RecruitingPhase 4
Early cholesterol treatment after a heart attack
This study tests whether adding an extra cholesterol-lowering drug (bempedoic acid) to the usual treatment soon after a heart attack or related event can lower 'bad' cholesterol more effectively. It may help reduce the risk of future heart problems.
Taipei, Taipei CityAges 18 years+ - NCT06520904RecruitingPhase 4
PCSK9 inhibitor for coronary plaque in heart disease
This study tests whether a medication called a PCSK9 inhibitor (a type of drug that lowers bad cholesterol) can improve the buildup of plaque in heart arteries. It may be an option for people with coronary artery disease who have not been helped enough by statins alone.
Ürümqi, XinjiangAges 18–65 - NCT05076019Recruiting
Atorvastatin during heart valve surgery for patients over 60
This trial studies whether taking atorvastatin (a cholesterol medicine) around the time of surgical aortic valve replacement can improve outcomes. It is mainly for people who have not taken similar medicines recently and do not have certain heart rhythm or liver/kidney problems.
OdenseAges 60–95 - NCT07727681RecruitingPhase 4
Statins to Prevent Atrial Fibrillation After Lung Surgery
This trial tests whether taking a statin before and after lung surgery can prevent a common heart rhythm problem called atrial fibrillation (AFib). If you are 60 or older and having a lung segment or lobe removed, this study may help you avoid AFib after your operation.
BeijingAges 60 years+ - NCT07704918Recruiting
Study: Lowering cholesterol during melanoma immunotherapy
This study tests whether giving aggressive cholesterol-lowering medication to people starting immunotherapy for melanoma can improve heart health. It may help reduce the risk of heart problems during cancer treatment.
Aurora, ColoradoAges 55 years+ - NCT07680595RecruitingPhase 1/Phase 2
Statins and folic acid for unstable carotid plaque
This trial tests if adding folic acid to a statin can help stabilize plaques in the carotid artery (neck artery) to prevent stroke. You may qualify if you have carotid plaque and are not already on certain supplements.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT07634484RecruitingPhase 4
Pemafibrate for high cholesterol not controlled by statins
This study tests whether pemafibrate, a new medication, can lower cholesterol better when added to statin treatment in patients whose cholesterol remains high despite taking statins regularly. The goal is to see if this combination reduces heart disease risk.
HokkaidoAges 18 years+ - NCT05725096Recruiting
CT scan helps guide cholesterol and heart risk care
This study is testing how a special heart scan (coronary CT angiography) can help manage cholesterol levels and other heart risk factors in people who feel well and have no known heart disease. It may help doctors better decide what lifestyle or medicines you may need to lower risk.
Nanjing, JiangsuAges 40–69 - NCT04699279Recruiting
Statin after aortic surgery to protect heart and organs
This trial tests whether taking a cholesterol-lowering medicine (a statin) after certain aortic surgeries can reduce harmful changes in the heart and other organs. You might benefit by lowering the risk of ongoing damage after your acute aortic condition and surgery.
Guangzhou, GuangdongAges 18–85 - NCT07554820RecruitingPhase 4
Heart Protection in Rheumatoid Arthritis With New Medications
This study compares two treatment approaches for people with active rheumatoid arthritis who also have heart disease risk factors. It tests whether a newer drug called tofacitinib, combined with cholesterol medication, can better protect the heart than traditional TNF-inhibitor treatments.
Lahore, Punjab ProvinceAges 50–85 - NCT07530640RecruitingPhase 3
Statins to Help Children With Kawasaki Disease Heart Problems
This trial tests whether a cholesterol-lowering medication called atorvastatin can help children whose hearts were damaged by Kawasaki disease (a serious childhood illness that inflames blood vessels). The study may help reduce long-term heart complications.
ShanghaiAges 2–18 - NCT06588231Recruiting
Personalized exercise for older adults with heart disease
This study tests whether a personalized exercise program can help older people (60–75) with stable coronary heart disease improve their heart health. You would work with healthcare professionals to get an exercise plan tailored to your condition.
Nanjing, JiangsuAges 60–75
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Common questions
- Are there clinical trials for statin?
- Yes. Clin2 currently lists 81 recruiting statin studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a statin trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a statin trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.