Clinical trials · Philadelphia, PA
Type 1 diabetes clinical trials in Philadelphia
We’re tracking 33 recruiting type 1 diabetes studies with a site in or near Philadelphia — including Phase 2, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies near Philadelphia
- NCT07222332RecruitingPhase 3
Baricitinib for new type 1 diabetes to save insulin-making cells
This trial tests if baricitinib, a pill that calms the immune system, can protect the remaining insulin-making cells in people newly diagnosed with type 1 diabetes. If it works, you might keep making some of your own insulin longer.
Philadelphia, PennsylvaniaAges 1–35 - NCT06481904Recruiting
Registry for stage 2 type 1 diabetes
This study tracks people with stage 2 type 1 diabetes to see how they do over time, either with or without treatment with a drug called TZIELD. It helps doctors learn more about the disease and the effects of this treatment.
Philadelphia, PennsylvaniaAges Any age - NCT06739122RecruitingPhase 3
A study of dulaglutide for children with type 2 diabetes
This trial tests if a weekly injection of dulaglutide (Trulicity) can help children with type 2 diabetes control their blood sugar when used together with metformin and/or insulin. It may be an option for kids who are overweight.
Philadelphia, PennsylvaniaAges 10–17 - NCT07654374RecruitingPhase 3
Study of a new pill for weight loss and diabetes
This study tests a new daily pill (aleniglipron) to help adults with excess weight and type 2 diabetes lose weight and improve blood sugar control. It may be a good fit if you have a BMI of 27 or higher and your diabetes is managed with A1c between 6.5% and 10%.
Philadelphia, PennsylvaniaAges 18–79 - NCT06325202Recruiting
A study on preventing low blood sugar with a closed loop system
This trial tests whether a closed-loop insulin pump combined with education can help people with type 1 diabetes better recognize and avoid dangerously low blood sugar. It may be a good fit if you've had diabetes for a long time and have trouble sensing when your blood sugar drops.
Philadelphia, PennsylvaniaAges 18–75 - NCT07008469Enrolling by invitationPhase 3
Long-term safety study of del-desiran for DM1
This study tests whether the drug del-desiran continues to be safe and effective for people with DM1 (myotonic dystrophy type 1) after they complete an earlier study. You'll receive the drug and have regular check-ups to see how you're doing.
Philadelphia, PennsylvaniaAges 16 years+ - NCT07444203Recruiting
Study of kidney tissue in diabetes-related kidney disease
This study collects and studies kidney tissue (from a biopsy or surgery) from people with diabetes-related kidney disease to learn more about the condition. You may be able to help if you've already had a kidney biopsy or certain kidney surgeries.
Philadelphia, PennsylvaniaAges 18 years+ - NCT07088068RecruitingPhase 3
Teplizumab for newly diagnosed type 1 diabetes
This study tests whether teplizumab can help keep the body making insulin in people recently diagnosed with type 1 diabetes. It is for children and young adults aged 1 to 25, and compares the drug against a placebo.
Philadelphia, PennsylvaniaAges 1–25 - NCT07743450RecruitingPhase 3
Daily oral medication for weight loss in adults with obesity and type 2 diabetes
This study tests a once-a-day pill for adults who are overweight or have obesity and also have type 2 diabetes. The goal is to see if the medication helps with weight loss and improves blood sugar control.
Philadelphia, PennsylvaniaAges 18 years+ - NCT07184775Recruiting
CGM vs finger-stick for type 2 diabetes in pregnancy
This trial tests if using a continuous glucose monitor (CGM) helps manage blood sugar better than finger-stick checks in pregnant women with type 2 diabetes. It aims to see if CGM leads to better sugar control and possibly healthier outcomes for you and your baby.
Philadelphia, PennsylvaniaAges 18 years+ - NCT07222137RecruitingPhase 3
Baricitinib to delay type 1 diabetes in at-risk people
This trial tests if baricitinib, a pill that calms the immune system, can slow down or delay the onset of type 1 diabetes in children and adults who are at high risk. It is for people whose blood sugar is already starting to rise but who do not yet need insulin.
Philadelphia, PennsylvaniaAges 1–35 - NCT07064473RecruitingPhase 3
Testing vicadrostat plus empagliflozin for diabetes, high blood pressure, and heart disease
This study tests a new pill called vicadrostat taken with another medicine (empagliflozin) to see if it helps people with type 2 diabetes, high blood pressure, and heart disease. It may reduce the risk of heart problems, but you must not have had heart failure or use certain other heart medications.
Philadelphia, PennsylvaniaAges 18 years+ - NCT07282613RecruitingPhase 3
CagriSema for blood sugar and weight in children with type 2 diabetes
This study tests a new medicine called CagriSema to see if it can lower blood sugar and help with weight loss in children and teens with type 2 diabetes. It compares the medicine to a placebo (a look-alike with no active drug) over several months.
Philadelphia, PennsylvaniaAges 10–18 - NCT06832410RecruitingPhase 3
Testing VX-880 for type 1 diabetes with a kidney transplant
This trial tests a new treatment called VX-880 for people who have had type 1 diabetes for at least 5 years and have already received a kidney transplant. The goal is to see if VX-880 can improve blood sugar control while you continue your current transplant medications.
Philadelphia, PennsylvaniaAges 18–65 - NCT06880835Recruiting
Inhaled insulin vs injected insulin for exercise blood sugar drops in type 1 diabetes
This trial tests whether a new inhaled insulin (Technosphere) causes fewer low blood sugar episodes during exercise compared to standard injected insulin in people with type 1 diabetes who use an automated insulin pump. It may help you avoid hypoglycemia while staying active.
Philadelphia, PennsylvaniaAges 18–65 - NCT07564414RecruitingPhase 3
Weight Loss Study Comparing Two Doses of CagriSema
This study tests whether a new combination medication called CagriSema (in two different doses) helps people with obesity lose weight. You may qualify if you're 18 or older, have a BMI of 35 or higher, and either don't have type 2 diabetes or have it well-controlled.
Philadelphia, PennsylvaniaAges 18 years+ - NCT05390892RecruitingPhase 4
Preventing kidney and heart damage in type 2 diabetes
This study tests whether diabetes medicines can help prevent worsening heart and kidney problems in people with type 2 diabetes. You’ll be assigned by chance to one of these medicine types, and your other care will be adjusted for safety.
Philadelphia, PennsylvaniaAges 40–80 - NCT07662213RecruitingPhase 3
Elecoglipron vs semaglutide for type 2 diabetes
This study tests an experimental diabetes pill (elecoglipron) to see if it works as well as a current medicine, semaglutide, for people with type 2 diabetes who also have heart risk factors. It aims to help better control blood sugar and weight.
Philadelphia, PennsylvaniaAges 18 years+ - NCT04786262RecruitingPhase 3
A study of VX-880 and VX-017 for type 1 diabetes
This study tests two investigational drugs, VX-880 and VX-017, for people with type 1 diabetes who have trouble controlling their blood sugar and have frequent severe low blood sugar episodes. The goal is to see if these drugs can improve blood sugar control and reduce dangerous lows.
Philadelphia, PennsylvaniaAges 18–65 - NCT04024631Recruiting
Study genes and diabetes risk using body measurements
This study looks at how genetic risk relates to developing type 2 diabetes, using information from a biobank and body measurements like weight. It may help researchers better identify who is at higher risk before diabetes starts.
Philadelphia, PennsylvaniaAges 10–70 - NCT07187531RecruitingPhase 2
Testing a new drug to preserve insulin production in type 1 diabetes
This study tests a new drug called SAB-142, which aims to stop the immune system from attacking insulin-making cells in type 1 diabetes. It may help preserve your body's ability to make insulin. The trial will check if the drug is safe and effective.
Philadelphia, PennsylvaniaAges 5–40 - NCT04213547Recruiting
Sleep and blood sugar control in teens with type 2 diabetes
This study looks at how sleep timing and length relate to blood sugar control in teens with type 2 diabetes. It also checks whether teens who meet certain sleep and blood-sugar targets—and can follow sleep tracking—can take part in the study and feedback sessions.
Philadelphia, PennsylvaniaAges 12–20 - NCT05762107RecruitingPhase 2
Drug ZT-01 to reduce low blood sugar at night
This Phase 2 study tests ZT-01 to help prevent night-time low blood sugar (hypoglycemia) in people with type 1 diabetes. It may help if you’ve had low blood sugar during sleep or are at high risk based on recent glucose monitoring.
Philadelphia, PennsylvaniaAges 18–75 - NCT07784725RecruitingPhase 3
Study of a weight loss injection for adults with obesity
This study tests a new medicine to help adults with obesity or overweight lose weight. It's for people who have had trouble losing weight in the past and don't have diabetes.
Philadelphia, PennsylvaniaAges 18 years+
Hear when a new Type 1 diabetes trial opens near Philadelphia, PA
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Type 1 diabetes trials in other cities
Where these studies are running near Philadelphia
Institutions with a site for the recruiting type 1 diabetes studies listed above.
- Children's Hospital of Philadelphia · 4 studies
- University of Pennsylvania · 4 studies
- Thomas Jefferson University · 3 studies
- Research Site · 2 studies
- ACCOMPLISH-2 Research Site
- AURORA-2 Clinical Site
- Cardiology Consultants of Philadelphia
- Children's Hospital of Philadelphia (CHOP)
What taking part in a type 1 diabetes study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Looking wider? See all recruiting type 1 diabetes studies in Pennsylvania.
Common questions
- Are there type 1 diabetes clinical trials near Philadelphia?
- Yes. We're currently tracking 33 recruiting type 1 diabetes studies with a site near Philadelphia, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a type 1 diabetes study near Philadelphia?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Philadelphia to take part?
- Not necessarily. These studies have a site near Philadelphia, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a type 1 diabetes trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New type 1 diabetes studies open near Philadelphia regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.