Clinical trials · Pennsylvania
Type 1 diabetes clinical trials in Pennsylvania
We’re tracking 40 recruiting type 1 diabetes studies with a site in Pennsylvania — including Phase 1/Phase 2, Phase 2, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies in Pennsylvania
- NCT07088068RecruitingPhase 3
Teplizumab for newly diagnosed type 1 diabetes
This study tests whether teplizumab can help keep the body making insulin in people recently diagnosed with type 1 diabetes. It is for children and young adults aged 1 to 25, and compares the drug against a placebo.
Philadelphia, PennsylvaniaAges 1–25 - NCT07222137RecruitingPhase 3
Baricitinib to delay type 1 diabetes in at-risk people
This trial tests if baricitinib, a pill that calms the immune system, can slow down or delay the onset of type 1 diabetes in children and adults who are at high risk. It is for people whose blood sugar is already starting to rise but who do not yet need insulin.
Philadelphia, PennsylvaniaAges 1–35 - NCT07222332RecruitingPhase 3
Baricitinib for new type 1 diabetes to save insulin-making cells
This trial tests if baricitinib, a pill that calms the immune system, can protect the remaining insulin-making cells in people newly diagnosed with type 1 diabetes. If it works, you might keep making some of your own insulin longer.
Philadelphia, PennsylvaniaAges 1–35 - NCT05762107RecruitingPhase 2
Drug ZT-01 to reduce low blood sugar at night
This Phase 2 study tests ZT-01 to help prevent night-time low blood sugar (hypoglycemia) in people with type 1 diabetes. It may help if you’ve had low blood sugar during sleep or are at high risk based on recent glucose monitoring.
Pittsburgh, PennsylvaniaAges 18–75 - NCT07662213RecruitingPhase 3
Elecoglipron vs semaglutide for type 2 diabetes
This study tests an experimental diabetes pill (elecoglipron) to see if it works as well as a current medicine, semaglutide, for people with type 2 diabetes who also have heart risk factors. It aims to help better control blood sugar and weight.
Feasterville-Trevose, PennsylvaniaAges 18 years+ - NCT04786262RecruitingPhase 3
Study of VX-880 for long-standing type 1 diabetes
This Phase 3 trial tests how safe, tolerable, and effective VX-880 is for people with type 1 diabetes who have had it for many years. It may help reduce problems related to blood sugar swings, especially severe low blood sugar episodes.
Philadelphia, PennsylvaniaAges 18–65 - NCT05277558Recruiting
MRI and brain testing in teens at risk for type 2 diabetes
This study looks at brain health in teens with normal weight, overweight, or obesity who are at risk for type 2 diabetes. It may help researchers understand how weight and diabetes risk affect the brain, using MRI scans and learning/memory tests.
Pittsburgh, PennsylvaniaAges 12–17 - NCT06264258Recruiting
Game-based diabetes education for kids
This study tests a fun video game to help children aged 6–12 with type 1 diabetes learn about managing their condition. It may improve how kids check their blood sugar and take insulin.
Pittsburgh, PennsylvaniaAges 6–12 - NCT06481904Recruiting
Registry for stage 2 type 1 diabetes
This study tracks people with stage 2 type 1 diabetes to see how they do over time, either with or without treatment with a drug called TZIELD. It helps doctors learn more about the disease and the effects of this treatment.
Philadelphia, PennsylvaniaAges Any age - NCT06832410RecruitingPhase 3
Testing VX-880 for type 1 diabetes with a kidney transplant
This trial tests a new treatment called VX-880 for people who have had type 1 diabetes for at least 5 years and have already received a kidney transplant. The goal is to see if VX-880 can improve blood sugar control while you continue your current transplant medications.
Philadelphia, PennsylvaniaAges 18–65 - NCT06959316Recruiting
T1D Pregnancy & Me
This study tests how well continuous glucose monitors (CGMs) help manage type 1 diabetes during pregnancy. If you are pregnant, have type 1 diabetes, and regularly use a CGM, this trial may help you track your blood sugar and improve your baby's health.
Philadelphia, PennsylvaniaAges 18 years+ - NCT07061574RecruitingPhase 1/Phase 2
Low-dose ATG with Adalimumab or Verapamil for new type 1 diabetes
This study tests if giving a low dose of an immune-suppressing drug (ATG) followed by either adalimumab or verapamil can help preserve insulin production in people recently diagnosed with type 1 diabetes. You may qualify if you are 9 to 20 years old, have had type 1 diabetes for less than 6 months, and have some natural insulin left.
Pittsburgh, PennsylvaniaAges 9–20 - NCT07086443RecruitingPhase 4
Testing a new wound therapy for diabetic foot ulcers
This study tests a new wound therapy for diabetic foot ulcers that haven't healed with standard care. It aims to see if the therapy helps these ulcers heal better and faster.
Monroeville, PennsylvaniaAges 18 years+ - NCT07142252RecruitingPhase 2
New drug for recently diagnosed type 1 diabetes
This trial tests a new medicine (rezpegaldesleukin) to see if it can help preserve the body's ability to make some insulin in people recently diagnosed with type 1 diabetes. It's for children and adults diagnosed within the past 100 days.
Pittsburgh, PennsylvaniaAges 8–45 - NCT07187531RecruitingPhase 2
Testing a new drug to slow type 1 diabetes progression
This trial tests an experimental drug called SAB-142 to see if it can slow down or stop the progression of type 1 diabetes. It is designed for people who were recently diagnosed and still produce some insulin on their own.
Philadelphia, PennsylvaniaAges 5–40 - NCT07076199RecruitingPhase 3
Weekly vs daily insulin for type 1 diabetes
This study tests a new once-weekly insulin (icodec) against a standard daily insulin (glargine), both taken with mealtime insulin. It aims to see which works better to control blood sugar in adults with type 1 diabetes.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06420661Enrolling by invitation
School program for children with type 1 diabetes
This study tests a special program called SPACE that helps children with type 1 diabetes by working together with their school nurse and diabetes team. The goal is to improve diabetes care and support at school.
Pittsburgh, PennsylvaniaAges 5–12 - NCT04024631Recruiting
Study genes and diabetes risk using body measurements
This study looks at how genetic risk relates to developing type 2 diabetes, using information from a biobank and body measurements like weight. It may help researchers better identify who is at higher risk before diabetes starts.
Philadelphia, PennsylvaniaAges 10–70 - NCT04213547Recruiting
Sleep and blood sugar control in teens with type 2 diabetes
This study looks at how sleep timing and length relate to blood sugar control in teens with type 2 diabetes. It also checks whether teens who meet certain sleep and blood-sugar targets—and can follow sleep tracking—can take part in the study and feedback sessions.
Philadelphia, PennsylvaniaAges 12–20 - NCT07184775Recruiting
CGM vs finger-stick for type 2 diabetes in pregnancy
This trial tests if using a continuous glucose monitor (CGM) helps manage blood sugar better than finger-stick checks in pregnant women with type 2 diabetes. It aims to see if CGM leads to better sugar control and possibly healthier outcomes for you and your baby.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06848361Enrolling by invitation
Using your health data to manage type 2 diabetes
This study tests whether helping you use your own health information (like blood sugar numbers) on a smartphone app can improve your diabetes self-care. You may join if your blood sugar levels are higher than target and you are not using insulin.
Pittsburgh, PennsylvaniaAges 25–75 - NCT06880835Recruiting
Inhaled insulin vs injected insulin for exercise blood sugar drops in type 1 diabetes
This trial tests whether a new inhaled insulin (Technosphere) causes fewer low blood sugar episodes during exercise compared to standard injected insulin in people with type 1 diabetes who use an automated insulin pump. It may help you avoid hypoglycemia while staying active.
Philadelphia, PennsylvaniaAges 18–65 - NCT06325202Recruiting
A study on preventing low blood sugar with a closed loop system
This trial tests whether a closed-loop insulin pump combined with education can help people with type 1 diabetes better recognize and avoid dangerously low blood sugar. It may be a good fit if you've had diabetes for a long time and have trouble sensing when your blood sugar drops.
Philadelphia, PennsylvaniaAges 18–75 - NCT00097292Recruiting
Preventing Type 1 Diabetes in At-Risk People
This study looks for people at high risk of developing type 1 diabetes (based on family history or blood markers) and follows them over time to understand disease development. The goal is to eventually prevent or delay type 1 diabetes in people who don't have it yet.
Pittsburgh, PennsylvaniaAges 2–45
Type 1 diabetes trials by city in Pennsylvania
Where these studies are running in Pennsylvania
Institutions with a site for the recruiting type 1 diabetes studies listed above.
- Children's Hospital of Philadelphia · 7 studies
- University of Pennsylvania · 6 studies
- University of Pittsburgh · 4 studies
- UPMC Children's Hospital of Pittsburgh · 4 studies
- Thomas Jefferson University Hospital · 3 studies
- Montefiore Hospital Clinical and Translational Research Center
- Perelman Center for Advanced Medicine
- Research Site
What taking part in a type 1 diabetes study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Type 1 diabetes trials in other states
Common questions
- Are there type 1 diabetes clinical trials in Pennsylvania?
- Yes. We're currently tracking 40 recruiting type 1 diabetes studies with a site in Pennsylvania, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a type 1 diabetes study in Pennsylvania?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Pennsylvania to take part?
- Not necessarily. These studies have a site in Pennsylvania, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a type 1 diabetes trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New type 1 diabetes studies open in Pennsylvania regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.