Rheumatology & orthopedics
Bones, joints & muscles clinical trials
Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We’re tracking 4,832 recruiting studies in this area right now.
By phase
- Not applicable3,967
- Phase 2222
- Phase 4195
- Phase 1191
- Phase 3151
- Phase 1/Phase 273
- Phase 2/Phase 333
Top conditions
- Knee Osteoarthritis184
- Rheumatoid Arthritis141
- Fibromyalgia102
- Osteoporosis88
- Osteoarthritis74
- Osteoarthritis, Knee73
- Rheumatoid Arthritis (RA)64
- Shoulder Pain50
- Psoriatic Arthritis47
- Hip Osteoarthritis41
- Systemic Lupus Erythematosus41
- Duchenne Muscular Dystrophy39
- Chronic Pain38
- Degenerative Disc Disease38
- Total Knee Arthroplasty38
- Musculoskeletal Pain36
- Pain34
- Dermatomyositis31
Leading sponsors
- Riphah International University110
- Cairo University72
- Istituto Ortopedico Rizzoli71
- Assistance Publique - Hôpitaux de Paris37
- Foundation University Islamabad34
- Mayo Clinic29
- Massachusetts General Hospital27
- National Taiwan University Hospital25
- Chinese University of Hong Kong22
- Hacettepe University22
Where studies are running
- California208
- New York94
- Florida80
- Arizona76
- Massachusetts76
- Maryland73
- Texas64
- Alabama57
- Illinois54
- Pennsylvania50
Recruiting studies4,832 total
- NCT04173715Recruiting
Study measuring movement and behavior in older adults
This study checks how well you move and how you behave during simple tasks. It may help researchers understand physical function and activity patterns in older adults.
ToledoAges 65 years+ - NCT04067596Recruiting
Growth-limiting leg surgery for very tall teens
This trial looks at a surgery that slows future height growth in adolescents who are very tall and still growing. It may help reduce how much more height they may gain by limiting growth at the knee/leg growth plates.
CréteilAges 8 years+ - NCT03806881Enrolling by invitation
Follow-up after shoulder replacement using a patient-specific implant
This study follows people after a primary or revision shoulder joint replacement when the shoulder socket bone has severe damage. It checks long-term outcomes and how well the patient-specific implant and required therapy work for recovery.
HerentalsAges 18 years+ - NCT03650010Recruiting
Study of ankle replacement outcomes over many years
This study looks at how well total ankle replacement surgery works and what the scans show over time. It mainly includes adults who had the surgery in a specific date range, to better understand results after ankle replacement.
Milan, MilanoAges 18 years+ - NCT07749534Recruiting
Living with spinal deformity: quality of life study
This study follows adults with spinal deformity to understand how the condition and its treatments affect daily life, emotions, and physical function. It aims to improve care and support for people like you.
LeuvenAges 18 years+ - NCT07750080Recruiting
Comparing two therapies for tennis elbow in menopausal women
This study tests whether a combination of electrical therapies or shock wave therapy works better for reducing pain and improving function in menopausal women with tennis elbow that has lasted at least 3 months.
CairoAges 45–55 - NCT07559539Recruiting
Life after scoliosis surgery: long-term outcomes study
This research follows adults who had spine-straightening surgery (called fusion) for adolescent scoliosis in their teens. Researchers want to understand how surgery affects your daily life, physical function, and quality of life 10–25 years later.
Warsaw, Masovian VoivodeshipAges 25–40 - NCT07744789Recruiting
Knee ligament stiffness and osteoarthritis treatment
This study looks at how knee ligament stiffness changes in people with knee osteoarthritis and compares it to healthy volunteers. It may help find better ways to treat knee pain and stiffness.
Taipei, Taipei CityAges 20 years+ - NCT07750379Recruiting
Acid-reducing medicine for aspiration in children with laryngomalacia
This study tests whether giving a common acid-reducing medicine (a proton pump inhibitor) to children with laryngomalacia can reduce choking and aspiration. It may help if your child has frequent choking episodes.
Minya, Minya GovernorateAges 6 months–5 years - NCT07353931RecruitingPhase 3
Study of eloralintide for knee osteoarthritis pain in people with overweight or obesity
This trial tests an investigational drug called eloralintide to see if it can reduce knee pain in people with osteoarthritis who also have overweight or obesity. You may be able to join if you have knee osteoarthritis, a BMI of 27 or higher, and have tried to lose weight with diet before.
Mobile, AlabamaAges 18 years+ - NCT07153471RecruitingPhase 3
A study of an experimental pill for weight loss and knee arthritis
This trial tests an investigational medication (orforglipron) to see if it helps people with knee arthritis lose weight. You may qualify if you have overweight or obesity and have tried dieting before without lasting success.
Phoenix, ArizonaAges 18 years+ - NCT07199738Recruiting
Knee replacement study with a new implant option
This study tests a specific knee implant insert (LEGION Medial Stabilized) in people who need a total knee replacement due to arthritis or similar joint disease. It aims to see if the device is safe and works well over time.
Newton, MassachusettsAges 18–80 - NCT06724562Recruiting
Anti-IL1 therapy for severe FOP flare-ups
This trial is for people with FOP who have severe, frequent flare-ups. It follows those who are already starting an anti-IL1 medication (like anakinra) to see if it helps reduce flares and improve symptoms.
San Francisco, CaliforniaAges 6–30 - NCT07700225Recruiting
Long-term study of myotonic dystrophy type 1
This study is a long-term follow-up for people with myotonic dystrophy type 1. It aims to find better ways to measure how the disease progresses, which could help develop future treatments.
Richmond, VirginiaAges 18–70 - NCT07129226Recruiting
Smartwatch monitoring for leg and pelvis cancer recovery
This study uses a smartwatch to monitor your activity and recovery after treatment for sarcoma or bone cancer in your leg or pelvis. It helps your care team keep track of how you're doing from home.
Cleveland, OhioAges 18 years+ - NCT07573527Recruiting
Online therapy for upper back muscle pain from trigger points
This study tests whether remote physical therapy (done online) can help relieve neck and upper back pain caused by tight knots in your rhomboid muscles. You would receive guided exercises and treatment through video calls instead of visiting a clinic in person.
Karachi, SindhAges 18–35 - NCT07033390Enrolling by invitation
Study on orthopedic shoe comfort questionnaire
This study tests a new questionnaire that measures how people feel about wearing orthopedic shoes. It aims to make sure the survey is accurate and reliable for Turkish speakers.
Beykoz, IstanbulAges 16–75 - NCT07007663Recruiting
Directional preference in lumbar spinal stenosis
This study looks at whether people with lumbar spinal stenosis (a narrowing in the lower spine) have a 'directional preference'—a specific movement or position that eases their symptoms. If you have leg or buttock pain when walking, this trial may help find better ways to treat your condition.
Lake Success, New YorkAges 48 years+ - NCT07018960Recruiting
Chest wall repair with custom 3D-printed titanium implant
This study is testing a new way to repair large chest wall defects using a custom-made 3D-printed titanium implant. It may help people who need chest wall reconstruction after cancer surgery, a bad injury, or damage from infection or radiation.
Cruces, Basque CountryAges 18 years+ - NCT07067125Recruiting
Augmented reality physiotherapy for teens with scoliosis
This study explores how teens with scoliosis feel about using augmented reality (a technology that overlays digital images on the real world) during their physical therapy sessions. It aims to understand if AR makes therapy more engaging or helpful.
GaziantepAges 10–18 - NCT06901700Recruiting
Leg strength training at home for older adults
This study tests if doing leg strengthening exercises at home can improve muscle strength, balance, and daily function in older adults. It may help you stay steady on your feet and move more easily.
TaipeiAges 65–80 - NCT07073014Enrolling by invitationPhase 3
Long-term continuation of a follow-up study for a children's genetic condition called something in the world of a person who is like a head or foot specialist? Probably? (shortest version? of? a? person? condition? that? is? so? far? less? than? 60?? (time? of? a? person? limited???)?
this study is a long-term extension of the main study for the drug which from Bio? bi? whatever? in the name? by?...????
Wilmington, DelawareAges Any age - NCT06972680Enrolling by invitation
Finding the best dose for a shoulder block before surgery
This trial tests different volumes of a long-lasting numbing medicine (Exparel) injected around the shoulder nerves before arthroscopic surgery. The goal is to find the dose that provides the best pain relief.
Jiaxing, ZhejiangAges 18 years+ - NCT06981065Recruiting
Scandinavian study for displaced collar bone fractures
This trial tests different treatments for a specific type of broken collar bone (the outer end, near the shoulder) where the bone pieces are out of place. If you have this type of fracture, the study aims to find the best way to help it heal.
OdenseAges 18–65
Common questions
- How many bones, joints & muscles clinical trials are recruiting?
- Clin2 is tracking 4,832 recruiting rheumatology & orthopedics studies from the U.S. registry right now, out of 7,923 we cover in this area in total.
- What does “Bones, joints & muscles” cover here?
- Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We group each study into bones, joints & muscles based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a bones, joints & muscles trial near me?
- Use the search to filter bones, joints & muscles studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.