Rheumatology & orthopedics
Bones, joints & muscles clinical trials
Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We’re tracking 4,611 recruiting studies in this area right now.
By phase
- Not applicable3,768
- Phase 2217
- Phase 4200
- Phase 1182
- Phase 3139
- Phase 1/Phase 271
- Phase 2/Phase 334
Top conditions
- Knee Osteoarthritis172
- Rheumatoid Arthritis132
- Fibromyalgia105
- Osteoporosis82
- Osteoarthritis71
- Rheumatoid Arthritis (RA)68
- Osteoarthritis, Knee64
- Shoulder Pain48
- Hip Osteoarthritis43
- Psoriatic Arthritis40
- Degenerative Disc Disease39
- Chronic Pain38
- Total Knee Arthroplasty38
- Duchenne Muscular Dystrophy37
- Systemic Lupus Erythematosus37
- Musculoskeletal Pain35
- Osteoarthritis (OA) of the Knee32
- Pain32
Leading sponsors
- Riphah International University85
- Istituto Ortopedico Rizzoli69
- Cairo University65
- Assistance Publique - Hôpitaux de Paris36
- Foundation University Islamabad31
- Mayo Clinic28
- Massachusetts General Hospital25
- National Taiwan University Hospital25
- Hacettepe University23
- Tanta University22
Where studies are running
- California207
- New York87
- Florida82
- Maryland76
- Arizona72
- Massachusetts71
- Texas67
- Alabama59
- Illinois51
- Pennsylvania48
Recruiting studies4,611 total
- NCT07846618Recruiting
Mental fatigue and leg strength study
This study looks at how mental tiredness affects leg muscle strength. You will do some mental tasks and then leg exercises to see if your strength changes.
Pensacola, FloridaAges 18–39 - NCT07844707Recruiting
Exercise and health education for worker muscle and joint health
This study tests whether a combined exercise and health education program improves musculoskeletal health (muscles, bones, and joints) in industrial workers. If you join, you'll get structured exercise sessions and learn about staying healthy at work.
Zaragoza, ZaragozaAges 18–65 - NCT07843784Enrolling by invitation
Chatbot pain management for knee osteoarthritis
This trial tests a chatbot program to help people manage knee osteoarthritis pain. You’d use your smartphone to get support and exercises at home, which might help reduce pain and improve daily life.
Hong Kong, Hong KongAges 18 years+ - NCT07843381Recruiting
Testing a new drug for Sjögren's syndrome with lung disease
This clinical trial tests a new drug called telitacicept for people who have both Sjögren's syndrome and interstitial lung disease. The drug aims to reduce the immune system's attack on your body and may help improve lung symptoms.
BeijingAges 18–70 - NCT07845136Recruiting
Riddles to reduce pain and fear during child cast placement
This study tests whether solving riddles during cast placement helps children feel less pain, fear, and anxiety. It is a simple, non-drug approach that may make the experience more comfortable for your child.
Kilis, CentralAges 6–12 - NCT06414005RecruitingPhase 2/Phase 3
TPX-115 injection for partial-thickness rotator cuff tear
This trial tests an injection called TPX-115 for people with a partial-thickness rotator cuff tear (a shoulder tendon injury that doesn't go all the way through). It may help reduce pain and improve movement if you've had shoulder problems for more than 3 months despite other treatments.
Seongnam-si, Gyeonggi-doAges 19 years+ - NCT06156904Recruiting
Study of b.Bone bone graft for defects in arms, legs, pelvis
This trial is following patients who receive a bone graft using a product called b.Bone to treat bone defects in the arms, legs, or pelvis. Researchers will collect information during your regular follow-up visits to see how well the bone heals.
BerlinAges 18 years+ - NCT06189781RecruitingPhase 4
Pain shot vs epidural for hip surgery in kids with cerebral palsy
This study compares a pain injection to epidural anesthesia for children with cerebral palsy having hip surgery. The goal is to see which method provides better pain control during and after the procedure.
Los Angeles, CaliforniaAges Up to 18 years - NCT05933434RecruitingPhase 1/Phase 2
Stem cell injection trial for chronic knee osteoarthritis
This early-phase study tests an injection of donor stem cells placed into the knee joint to help reduce symptoms of knee osteoarthritis. You may be eligible if you have long-lasting knee pain from mild-to-moderate arthritis and meet safety and imaging requirements.
Aarhus NAges 40–75 - NCT06409962Recruiting
New school program for childhood obesity and prediabetes
This study tests a new program to help children with obesity, focusing on those with slightly higher blood sugar (prediabetes). It takes place at a school and requires both parent and child consent.
CórdobaAges 6–16 - NCT06341920Recruiting
BoneFit: exercise before hip or knee replacement
This trial tests a pre-surgery exercise program called BoneFit for people waiting at least 6 months for a hip or knee replacement. The goal is to see if getting stronger before surgery helps recovery.
HullAges 18–75 - NCT06080633Recruiting
Facial prediction tech for people with no teeth
This study tests a new facial prediction technology that helps create better-fitting dentures for people with no natural teeth. It may improve how your dentures look and feel.
Leuven, HeverleeAges 50–100 - NCT07840391Recruiting
Recovery after same-day knee replacement surgery
This study looks at how your physical activity, sleep, and knee function change after you go home the same day as your knee replacement surgery. It aims to help you recover better by understanding these factors.
TampereAges Up to 80 years - NCT07838064Recruiting
Study of infection markers in hip revision surgery
This study looks for tiny markers in your blood and tissue that can tell whether a hip replacement is failing because of infection or another reason. By taking extra samples during your planned revision surgery, researchers hope to improve how infections are diagnosed in the future.
PortsmouthAges 18 years+ - NCT07834736Recruiting
Titanium implant for lower back disc pain
This study tests a new titanium implant to help stabilize the lower spine in people with painful, worn-out discs. It aims to see if the implant works well and is safe in everyday practice.
Madrid, MadridAges Any age - NCT07834749Recruiting
Fortilink-SC device study for neck and spinal stenosis
This study tests a new spinal device to see how well it works for people with neck pain and spinal stenosis. It may help reduce pain and improve function.
Madrid, MadridAges Any age - NCT07834931Recruiting
Spine implant for low back pain from disc degeneration
This study tests an implant placed in the lower spine to treat back pain caused by disc degeneration. It aims to see if the implant helps reduce pain and improve function in people who have not improved with other treatments.
Madrid, MadridAges Any age - NCT07841509Recruiting
Remote electrical neuromodulation for migraine and fibromyalgia
This study tests a wearable device that uses gentle electrical signals to reduce pain in people with migraine or fibromyalgia. It may help by changing how the brain processes pain signals.
Bridgewater, New JerseyAges 18 years+ - NCT07837427Recruiting
Different water pressures during minimally invasive back surgery
This study compares two different water pressures used during a minimally invasive back surgery to see if one causes fewer complications and gives the surgeon a clearer view. It aims to help improve recovery and surgical outcomes for people with lower back problems.
Kunming, YunnanAges 18–75 - NCT07841067Recruiting
3D-printed vs. milled plates for jaw surgery
This study compares two types of titanium plates (3D-printed vs. traditionally milled) used to hold the upper jaw in place after corrective jaw surgery. It aims to see which type is more accurate and reduces surgery time, which could mean a faster recovery for you.
Cairo, New Cairo, Fifth SettlementAges 18 years+ - NCT07834177Recruiting
Comparing two neck and spine movement exercises for chronic neck pain
This study compares two types of gentle neck and spine movements (called 'glides') to see which one works better for people with chronic neck pain related to 'upper cross syndrome' (a pattern of tight and weak muscles in the neck and shoulders). The goal is to find a more effective way to reduce pain and improve posture.
Islamabad, Punjab ProvinceAges 20–40 - NCT07834840Enrolling by invitation
Diet education for gout patients on urate-lowering therapy
This trial tests whether extra diet advice helps people with gout who are already taking urate-lowering medicine. It might help them manage their condition better.
Suwon, Gyeonggi-doAges 19 years+ - NCT07838610Recruiting
Shoulder therapy with added back and neck moves for frozen shoulder
This study tests whether adding gentle back and neck movements to standard physical therapy helps improve shoulder pain and movement in people with frozen shoulder. The goal is to see if these extra moves make recovery faster or more complete.
Islamabad, Punjab ProvinceAges 40–60 - NCT07838558Recruiting
Comparing two muscle-relaxing exercises for lower back pain
This study compares two muscle-relaxing techniques to help people with lower cross syndrome, a common cause of low back pain and poor posture. If you join, you'll receive one of these physiotherapy approaches to see which works better for relieving your pain.
Islamabad, Punjab ProvinceAges 19–35
Common questions
- How many bones, joints & muscles clinical trials are recruiting?
- Clin2 is tracking 4,611 recruiting rheumatology & orthopedics studies from the U.S. registry right now, out of 7,492 we cover in this area in total.
- What does “Bones, joints & muscles” cover here?
- Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We group each study into bones, joints & muscles based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a bones, joints & muscles trial near me?
- Use the search to filter bones, joints & muscles studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.