Rheumatology & orthopedics
Bones, joints & muscles clinical trials
Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We’re tracking 4,843 recruiting studies in this area right now.
By phase
- Not applicable3,974
- Phase 2225
- Phase 4197
- Phase 1190
- Phase 3149
- Phase 1/Phase 275
- Phase 2/Phase 333
Top conditions
- Knee Osteoarthritis184
- Rheumatoid Arthritis140
- Fibromyalgia102
- Osteoporosis86
- Osteoarthritis74
- Osteoarthritis, Knee71
- Rheumatoid Arthritis (RA)66
- Shoulder Pain50
- Psoriatic Arthritis47
- Hip Osteoarthritis41
- Systemic Lupus Erythematosus41
- Duchenne Muscular Dystrophy39
- Degenerative Disc Disease38
- Chronic Pain37
- Total Knee Arthroplasty37
- Musculoskeletal Pain36
- Pain35
- Dermatomyositis31
Leading sponsors
- Riphah International University111
- Cairo University72
- Istituto Ortopedico Rizzoli71
- Assistance Publique - Hôpitaux de Paris37
- Foundation University Islamabad33
- Mayo Clinic29
- Massachusetts General Hospital27
- National Taiwan University Hospital25
- Chinese University of Hong Kong22
- Hacettepe University22
Where studies are running
- California211
- New York94
- Florida82
- Massachusetts76
- Arizona75
- Maryland73
- Texas65
- Alabama57
- Illinois55
- Pennsylvania50
Recruiting studies4,843 total
- NCT07303166Recruiting
Osteoporosis care decisions for frail elderly patients
This study learns from doctors in Alsace who treat osteoporosis in frail older patients. It aims to understand what helps or hinders their use of a practical guide. If you are a doctor who has used this guide, your insights could improve future care.
StrasbourgAges 18 years+ - NCT07303582RecruitingPhase 4
Freezing nerves to ease pain from muscle tightness
This study tests if freezing specific nerves (cryoneurolysis) can reduce pain caused by muscle tightness (spasticity) after a brain or spinal cord injury, or from multiple sclerosis. It is for people who already get Botox injections for this pain.
OxfordAges 18 years+ - NCT07304167Recruiting
Exercise video game program for women with fibromyalgia
This study tests whether playing a special exercise video game can help women with fibromyalgia feel better. You will be asked to play the game regularly and report how you feel.
IstanbulAges 30–70 - NCT07304323Recruiting
Predicting recovery after hip or knee replacement in 2018
This trial is for people who had hip or knee replacement surgery in 2018 at a specific hospital in Milan and then went to its rehabilitation unit. Researchers will use your medical records to build and test a tool that predicts recovery after joint replacement.
MilanAges 18 years+ - NCT07304505Recruiting
Probiotics for adults with rheumatoid arthritis
This study tests whether a daily probiotic supplement can help adults with rheumatoid arthritis. You must have a stable RA treatment plan and be willing to take the probiotic for the duration of the study.
Chicago, IllinoisAges 18 years+ - NCT07305168Recruiting
Breathing after tonsil surgery in children with sleep apnea
This study looks at breathing problems that can happen after tonsil or adenoid surgery in children who have sleep apnea. Researchers want to learn more so they can make surgery safer for kids.
Edegem, AntwerpAges 1–18 - NCT07308873Recruiting
Gait and knee osteoarthritis pain study
This study looks at how walking patterns relate to knee pain from osteoarthritis. It aims to understand individual differences to improve future treatments.
Pittsburgh, PennsylvaniaAges 45–80 - NCT07309003Recruiting
Electrical stimulation and exercise for knee osteoarthritis
This study tests whether a special electrical stimulation (called FES) combined with exercise can help strengthen the muscles around your knee. It may reduce pain and improve function for people with moderate knee osteoarthritis.
Ankara, AnkaraAges 50–65 - NCT07312448Recruiting
Comparing two ways to fix a sunken chest in teens
This trial looks at two surgical methods for correcting pectus excavatum (a sunken chest) in teens. It compares the modified Nuss technique with the classic one to see which works best.
StrasbourgAges 11–18 - NCT07312981Recruiting
Diet tracking study for advanced kidney disease
This study compares different ways to record what you eat and drink for people with advanced kidney disease. It may help find easier methods for dietary tracking.
Herlev, Capital RegionAges 18 years+ - NCT07313449Recruiting
Knee replacement study: 1-year results for a specific prosthesis
This study looks at how well a certain type of cemented total knee replacement works after at least one year. It may help doctors understand long-term outcomes for this specific knee implant.
StrasbourgAges 18 years+ - NCT07314840Recruiting
Ultrasound study for extra tendon spots in tennis elbow
This study uses ultrasound to check for extra inflammation spots in people with tennis elbow (lateral epicondylitis). It may help clarify why some people have ongoing elbow pain.
Istanbul, MaltepeAges 18–60 - NCT07315061RecruitingPhase 2
Testing D-2570 for active psoriatic arthritis
This trial tests an oral medication, D-2570, for people with active psoriatic arthritis. It aims to see if the drug can reduce joint pain and swelling.
Chengdu, SichuanAges 18–70 - NCT07315841RecruitingPhase 4
Dye Imaging for Tenosynovial Giant Cell Tumor Surgery
This trial tests whether a special dye (Indocyanine Green) used during surgery can help doctors see Tenosynovial Giant Cell Tumors more clearly. It may help make the surgery more precise.
ShanghaiAges 18–75 - NCT07316933Recruiting
Exercise with light blood flow restriction before knee replacement
This trial tests if a specific type of exercise, done with a cuff that lightly restricts blood flow to your leg, can help you get stronger and recover better while you wait for knee replacement surgery. The blood flow restriction is carefully controlled and adjusted during exercise, which may make the workout more effective.
Valencia, ValenciaAges 50–85 - NCT07317570Recruiting
Body awareness therapy for jaw pain and function
This study tests whether body awareness therapy (gentle exercises that help you notice how your body moves and feels) can reduce jaw pain, improve function, and help with related emotional stress. It is for people with long-term jaw joint problems.
RizeAges 18 years+ - NCT07318896Recruiting
Agar and collagen supplement study for knee pain
This trial tests whether a supplement made from agar and collagen can help reduce knee pain in people with mild to moderate osteoarthritis. If you are between 40 and 70 and have knee pain, this may be an option for you.
Reus, TarragonaAges 40–70 - NCT07318987Recruiting
Nerve release surgery for knee pain relief
This study tests if surgically releasing a nerve in the knee (the saphenous nerve) can reduce pain in people with patellofemoral pain syndrome (pain around the kneecap). If you've had anterior knee pain for at least six weeks and the nerve test is positive, this trial may offer relief.
CairoAges 18–35 - NCT07320118Recruiting
Knee cartilage repair and osteoarthritis prevention study
This study looks at whether fixing knee cartilage damage can prevent arthritis later. It compares different treatments to see if they help avoid long-term joint problems.
OswestryAges Any age - NCT07320417Recruiting
Preserving sinus lining during maxillary surgery
This study tests a modified surgery technique that keeps the sinus membrane intact while removing part of the upper jaw. It aims to reduce complications and help bone healing for patients with growths in the upper jaw that haven't spread to the sinus cavity.
ShanxiAges 18–75 - NCT07320846Recruiting
Exercise and gene activity in rheumatoid arthritis
This trial tests whether exercise training can affect gene activity (lncRNA) in rheumatoid arthritis patients with lung involvement. It may show how exercise helps manage the disease.
Istanbul, TurkeyAges 18–75 - NCT07321158Recruiting
Electrical stimulation for arm spasticity after first injury
This trial tests whether different pulse durations of electrical stimulation (NMES) can reduce muscle tightness (spasticity) in the arm after a first-time brain or spinal cord injury. It uses special brain-wave tests to measure changes.
Athens, AtticaAges 18 years+ - NCT07321340Recruiting
Optimizing insoles for rheumatoid arthritis patients
This trial tests whether custom-fit insoles can improve foot pain and walking for people with rheumatoid arthritis. It aims to find the best insole design for each patient.
Saint-EtienneAges 18 years+ - NCT07321977Recruiting
Walking test with a portable device for neuromuscular disease
This study tests a portable device that analyzes walking without markers. It aims to see if it can help assess walking in people with neuromuscular diseases and healthy volunteers, which could lead to simpler check-ups.
ParisAges 18–65
Common questions
- How many bones, joints & muscles clinical trials are recruiting?
- Clin2 is tracking 4,843 recruiting rheumatology & orthopedics studies from the U.S. registry right now, out of 7,987 we cover in this area in total.
- What does “Bones, joints & muscles” cover here?
- Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We group each study into bones, joints & muscles based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a bones, joints & muscles trial near me?
- Use the search to filter bones, joints & muscles studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.