Rheumatology & orthopedics
Bones, joints & muscles clinical trials
Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We’re tracking 4,832 recruiting studies in this area right now.
By phase
- Not applicable3,967
- Phase 2222
- Phase 4195
- Phase 1191
- Phase 3151
- Phase 1/Phase 273
- Phase 2/Phase 333
Top conditions
- Knee Osteoarthritis184
- Rheumatoid Arthritis141
- Fibromyalgia102
- Osteoporosis88
- Osteoarthritis74
- Osteoarthritis, Knee73
- Rheumatoid Arthritis (RA)64
- Shoulder Pain50
- Psoriatic Arthritis47
- Hip Osteoarthritis41
- Systemic Lupus Erythematosus41
- Duchenne Muscular Dystrophy39
- Chronic Pain38
- Degenerative Disc Disease38
- Total Knee Arthroplasty38
- Musculoskeletal Pain36
- Pain34
- Dermatomyositis31
Leading sponsors
- Riphah International University110
- Cairo University72
- Istituto Ortopedico Rizzoli71
- Assistance Publique - Hôpitaux de Paris37
- Foundation University Islamabad34
- Mayo Clinic29
- Massachusetts General Hospital27
- National Taiwan University Hospital25
- Chinese University of Hong Kong22
- Hacettepe University22
Where studies are running
- California208
- New York94
- Florida80
- Arizona76
- Massachusetts76
- Maryland73
- Texas64
- Alabama57
- Illinois54
- Pennsylvania50
Recruiting studies4,832 total
- NCT06458166Recruiting
Youth soccer fatigue and jump performance study
This study looks at how tired muscles get after a soccer match and how that affects jumping ability and how you feel. It may help coaches understand recovery needs in young elite players.
Maia, Porto DistrictAges 16–21 - NCT06456099Recruiting
Home exercises with a steroid shot for hip pain
This trial tests whether adding a steroid injection to a home exercise program helps people with long-term pain on the outside of the hip. It aims to find a better way to manage your pain and improve daily function.
GistrupAges 35 years+ - NCT06400862RecruitingPhase 1
Treating knee cartilage damage with lab-grown bone marrow tissue
This trial tests a new treatment that uses your own bone marrow cells to grow a piece of tissue to repair damaged knee cartilage. It's for people with a single, medium-sized cartilage injury on the thigh bone part of the knee joint that hasn't gotten better with other treatments.
JordonAges 18–60 - NCT06434272Recruiting
Blood flow restriction exercise after Achilles tendon rupture
This study tests whether adding blood flow restriction (using a special cuff) to standard rehabilitation exercises can help people with a torn Achilles tendon recover better. It might be an option if you recently ruptured your Achilles and started treatment within 72 hours.
Aarhus NAges 18 years+ - NCT06306833Recruiting
Biofeedback therapy for chronic low back pain
This study tests if a therapy that uses special sensors to help you relax your back muscles (called surface EMG biofeedback) can reduce chronic low back pain. If you have ongoing low back pain for at least 3 months, you may be able to join.
Karachi, SindhAges 25–75 - NCT06189079Recruiting
Arterial embolization for painful bone metastases
This study tests a procedure called arterial embolization, which blocks blood flow to bone tumors, to see if it can reduce pain or prevent fractures. It is for people with bone cancer that has spread from another cancer (metastases).
Bologna, Emilia-RomagnaAges 18 years+ - NCT06203756Enrolling by invitation
Robotic-Assisted Knee Replacement Outcomes Study
This study tests a robotic-assisted system for knee replacement surgery. It aims to see how well patients do with the robotic help.
Flagstaff, ArizonaAges Any age - NCT06257979Recruiting
Infection check during repeat rotator cuff surgery
This study looks for unexpected bacteria in the shoulder during repeat rotator cuff surgery. It aims to learn how often these hidden infections happen so doctors can better treat patients.
BeaumontAges 18 years+ - NCT06178497Recruiting
5-Year Check-In After ACL Repair
This study checks on people who had ACL (anterior cruciate ligament) repair surgery 5 years ago to see how well their knee is doing. It looks at a specific type of ACL tear (a 'proximal' tear) and helps doctors understand long-term results.
Lille, Choisir Une RégionAges 18 years+ - NCT06287021Recruiting
Bone healing after hip replacement with two types of titanium cups
This trial compares how bone grows around two different titanium cups used in hip replacement surgery. It aims to see which cup design leads to better bone remodeling and stability after the procedure.
MilanAges 40–85 - NCT06224660RecruitingPhase 1
Gene therapy for heart problems in Duchenne muscular dystrophy
This trial tests an experimental therapy for heart weakness caused by Duchenne muscular dystrophy. It aims to improve how heart cells handle calcium to protect heart function.
Kansas City, KansasAges 18 years+ - NCT06212947Recruiting
An observational study for children with hypochondroplasia
This study observes children with hypochondroplasia to learn more about the condition. It does not involve any treatment—just monitoring and data collection to help future research.
Phoenix, ArizonaAges Up to 15 years - NCT06240013Recruiting
Foam rolling vs. stretching for muscle recovery
This study compares two simple ways to help muscles stretch and recover: foam rolling (using a foam cylinder to massage muscles) and a stretching technique called PNF (contracting and relaxing muscles). It looks at how these methods affect flexibility and muscle function in amateur athletes.
Istanbul, None SelectedAges 18–30 - NCT06279468Recruiting
Disc release for teen scoliosis
This trial tests if releasing the disc between vertebrae can better correct a specific curve type (Lenke 5) in teens with scoliosis. It aims to improve spinal alignment with less stiffness after surgery.
Beijing, Beijing MunicipalityAges 10–18 - NCT06259968Recruiting
Electrical stimulation after ACL surgery recovery trial
This trial tests if adding electrical stimulation to standard physical therapy helps people recover strength and movement after ACL reconstruction surgery. It compares two rehab programs starting within days after surgery.
Veranópolis, Rio Grande do SulAges 18–40 - NCT06169800Recruiting
Biologic patch for first-time kneecap dislocation surgery
This trial tests adding a biologic material (a substance that helps healing) to the standard surgery that repairs the ligament on the inner side of the kneecap. It is for people who have just dislocated their kneecap for the first time, to see if the biologic improves recovery.
Canmore, AlbertaAges 13–30 - NCT06240221Enrolling by invitation
Tracking real-world use of the Saber-C cervical fusion device
This registry tracks how the Saber-C implant works in real-life neck surgeries. It gathers information to help doctors understand outcomes for people like you.
Paducah, KentuckyAges 18 years+ - NCT06321042Recruiting
Knee replacement study using sensor-guided implant placement
This study tests whether using small motion sensors during knee replacement surgery leads to better outcomes. It is for people aged 50–84 with severe knee pain from arthritis or bone damage who are scheduled for a first-time cemented total knee replacement.
Bologna, ItaliaAges 50–85 - NCT06207084Recruiting
Home exercise program for people with physical disabilities
This study tests a home-based exercise program for people with permanent physical disabilities that limit mobility. The goal is to see if coaching and training sessions can help you become more active and improve your health.
Birmingham, AlabamaAges 18–89 - NCT06240780Enrolling by invitation
Incrediwear recovery study for ACL and MCL surgery
This trial tests whether wearing Incrediwear clothing helps you recover faster after arthroscopic knee surgery for ACL or MCL tears. It is designed for people about to have surgery and who want to improve their healing process.
Oklahoma City, OklahomaAges 18–65 - NCT06320288Recruiting
Balance and movement study in children with cerebral palsy
This study looks at how children with cerebral palsy control their trunk and center of mass while walking. It may help understand balance challenges and guide future therapies.
NancyAges 1.5 years–18 years - NCT06224998Recruiting
Schroth and Pilates for teenage scoliosis
This trial compares two types of exercise—Schroth and Pilates—to see which works better for teens with mild scoliosis. It may help improve posture, strength, and quality of life.
IzmirAges 10–18 - NCT06287840Recruiting
Canadian Bone Strength Development Study for Kids with Type 1 Diabetes
This study looks at how bones grow stronger in children with type 1 diabetes compared to typically developing children. Researchers will measure bone strength using special scans and other simple tests.
Saskatoon, SaskatchewanAges 10–12 - NCT05978336Recruiting
Physical activity help for older adults with walking difficulty
This study tests a program to help older adults who have some trouble walking become more active. If you are able to walk a short distance without major help and have no serious memory problems, you may be able to join and get support to move more safely.
Vancouver, British ColumbiaAges 70–89
Common questions
- How many bones, joints & muscles clinical trials are recruiting?
- Clin2 is tracking 4,832 recruiting rheumatology & orthopedics studies from the U.S. registry right now, out of 7,923 we cover in this area in total.
- What does “Bones, joints & muscles” cover here?
- Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We group each study into bones, joints & muscles based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a bones, joints & muscles trial near me?
- Use the search to filter bones, joints & muscles studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.