Rheumatology & orthopedics
Bones, joints & muscles clinical trials
Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We’re tracking 4,837 recruiting studies in this area right now.
By phase
- Not applicable3,970
- Phase 2223
- Phase 4196
- Phase 1191
- Phase 3149
- Phase 1/Phase 275
- Phase 2/Phase 333
Top conditions
- Knee Osteoarthritis185
- Rheumatoid Arthritis142
- Fibromyalgia102
- Osteoporosis88
- Osteoarthritis74
- Osteoarthritis, Knee72
- Rheumatoid Arthritis (RA)65
- Shoulder Pain50
- Psoriatic Arthritis47
- Hip Osteoarthritis41
- Systemic Lupus Erythematosus41
- Duchenne Muscular Dystrophy39
- Degenerative Disc Disease38
- Total Knee Arthroplasty38
- Chronic Pain37
- Musculoskeletal Pain36
- Pain35
- Dermatomyositis31
Leading sponsors
- Riphah International University110
- Cairo University72
- Istituto Ortopedico Rizzoli71
- Assistance Publique - Hôpitaux de Paris37
- Foundation University Islamabad34
- Mayo Clinic29
- Massachusetts General Hospital27
- National Taiwan University Hospital25
- Chinese University of Hong Kong22
- Hacettepe University22
Where studies are running
- California211
- New York94
- Florida80
- Massachusetts76
- Arizona75
- Maryland73
- Texas65
- Alabama57
- Illinois54
- Pennsylvania50
Recruiting studies4,837 total
- NCT07578935Recruiting
Stability and Jump Training After ACL Surgery
This study compares two types of exercise programs for people who had ACL (knee ligament) reconstruction surgery 1-3 years ago. The goal is to see which training approach—focusing on balance and stability or on jumping and power—helps restore better knee function and strength.
Lahore, Punjab ProvinceAges 20–40 - NCT07572968Recruiting
Walking and Balance Tests for Older Adults with Memory Concerns
This study looks at how older adults walk and balance when doing two tasks at once (like talking while walking). Researchers want to understand how mild memory concerns affect movement, which could help catch early brain changes.
Balıkesir, BigadiçAges 65 years+ - NCT07603154Enrolling by invitation
Massage therapy for superior cluneal nerve pinching
This trial tests a specific massage technique called 'Fenjin Tuina' for treating superior cluneal nerve entrapment syndrome, a condition where a nerve in the lower back and hip area becomes pinched or compressed. The study aims to see if this traditional Chinese massage approach can reduce pain and improve function.
Guangzhou, GuangdongAges 18–70 - NCT07597343Recruiting
Helping You Stick With Hip Pain Exercise Treatment
This study tests new ways to help people with lateral hip pain (pain on the outer side of the hip) stay motivated and consistent with their exercise program. The goal is to understand what helps patients do their exercises regularly so they can feel better.
Leicester, LeictershaireAges 18 years+ - NCT07539467Enrolling by invitation
Nerve Block and Tourniquet for Knee Surgery Pain Relief
This trial tests whether a nerve block (numbing injection near the thigh) combined with a tourniquet (pressure cuff) after knee replacement surgery reduces pain better than standard care. If it works, it could help patients recover more comfortably with less need for strong pain medications.
AnkaraAges 40–85 - NCT07602933Recruiting
Light Therapy for Muscle Fatigue from Electrical Stimulation
This study tests whether light therapy can reduce muscle fatigue and damage caused by electrical muscle stimulation. Researchers want to see if this non-invasive light treatment helps muscles recover faster.
Porto Alegre, Rio Grande do SulAges 18–45 - NCT07528248Recruiting
Posture exercises for upper back and neck pain
This study compares two types of gentle posture-correction exercises for people with upper cross syndrome—a condition where your shoulders round forward and your neck posture shifts. The trial tests which approach works better to reduce pain and improve how you stand and move.
Okāra, Punjab ProvinceAges 20–45 - NCT07573553Recruiting
Rib Mobilization and Posture Exercises for Upper Crossed Syndrome
This study tests whether combining rib mobilization (hands-on therapy to improve rib movement) with posture-correction exercises can reduce neck pain and improve posture in people with upper crossed syndrome (a postural condition causing rounded shoulders and forward head tilt). It may help you understand if this combination therapy works better than standard treatment.
Chak Six Hundred Twenty-four, Khyber PakhtunkhwatAges 20–45 - NCT07544212Recruiting
Infections after large leg prosthesis implants: tracking outcomes
This study examines infections that occur after people receive a large custom prosthesis (artificial leg) to replace lost bone or tissue. Researchers want to understand who gets infections, why, and how these infections affect long-term health and function.
Bologna, BOAges 14–100 - NCT07586397Recruiting
Hip Pain Treatment Study With Physical Activity Focus
This study tests a new approach to treating long-lasting hip pain that combines psychology and exercise. It's designed for people whose hip pain is affected by worry or stress, and who aren't as physically active as they'd like to be.
Boston, MassachusettsAges 18 years+ - NCT07541209RecruitingPhase 1/Phase 2
Safety and Efficacy of PTH-IA for Rare Genetic Bone Disorder
This trial tests a new medication called PTH-IA for people with a specific genetic mutation affecting the parathyroid hormone receptor. The study aims to see if the medication is safe and can help improve bone health in children and adults with this rare condition.
Bethesda, MarylandAges 3–100 - NCT07593235Recruiting
Treating Forward Head Posture with Two Physical Therapy Techniques
This study compares two hands-on treatment methods for forward head posture—a common problem where your head juts forward. Researchers want to see which technique works better at improving your posture and reducing strain on your neck and upper back.
Islamabad, Punjab ProvinceAges 18–40 - NCT07583836Recruiting
Early vs. delayed surgery for spinal cord injury recovery
This trial compares whether having surgery sooner or waiting longer after a spinal cord injury helps patients recover better. Researchers will track how well patients regain movement and function over time.
RawalpindiAges 18–60 - NCT07544576Enrolling by invitationPhase 4
Knee Arthritis Injection: Two Injection Methods Compared
This study compares two ways of injecting a steroid medication into arthritic knees: using landmark guidance (traditional method) with a higher dose versus ultrasound guidance (imaging) with a lower dose. The goal is to see which approach works better to reduce knee pain and improve function.
Ventura, CaliforniaAges 50 years+ - NCT07597980Recruiting
Exercise and diet program to strengthen muscles in older adults
This study tests whether a lifestyle program combining exercise and nutrition can help adults over 50 improve their muscle strength and function. You'll work with researchers to see if this approach helps with mobility and overall health.
Baton Rouge, LouisianaAges 50 years+ - NCT07569796Recruiting
Nerve Stimulation to Help Recover After ACL Surgery
This study tests whether stimulating your sciatic nerve (a major nerve in your leg) can help you recover better after ACL reconstruction surgery. The goal is to reduce pain and help you regain strength and movement.
Madrid, MadridAges 18–60 - NCT07539194Recruiting
Hyaluronic acid injection for wear-and-tear knee cartilage tears
This trial tests a single injection of hyaluronic acid (a lubricating fluid) into the knee to relieve pain from degenerative meniscus tears—the kind caused by age and wear, not injury. The goal is to see if it safely reduces pain and improves how well your knee works.
Milan, MIAges 35–75 - NCT07490366Recruiting
Exercise vs needle treatment for shoulder muscle pain
This study compares three treatments for long-term shoulder muscle pain: exercises, dry needling (tiny needles into tight muscle spots), and a numbing shot between muscle layers. It aims to find which works best for myofascial pain syndrome.
Istanbul, IstanbulAges 18–55 - NCT07515287Enrolling by invitation
Pilates for Back Pain Recovery in Middle-Aged Women
This study tests whether Pilates exercises can help women aged 45–60 with chronic lower back disc problems improve their balance, leg strength, and body awareness. Pilates focuses on core stability and controlled movement, which may help restore function lost due to the disc herniation.
Kahramanmaraş, onikişubatAges 45–60 - NCT07481578Recruiting
Exercise and gut health study for active men
This study looks at how your training load affects your gut bacteria and how that relates to exercise performance and muscle health. It may help understand overreaching in healthy men.
Leuven, Vlaams BrabantAges 18–45 - NCT07497217Recruiting
Change in runner screening test over 12 weeks
This study looks at how a screening test for runners changes over 12 weeks. It is for senior runners who are members of a running club and have completed several 10-kilometer races recently.
Zaragoza, ZaragozaAges 18 years+ - NCT07453498Recruiting
Nerve block for pain after hip replacement
This study tests if a specific nerve block (the psoas sheath block) helps reduce pain after hip replacement surgery. If you are having a hip replacement, you may be able to join and get this extra pain relief.
GalwayAges 18 years+ - NCT07492732Recruiting
Training methods and SIS stimulation for balance and strength
This trial compares different training methods and a type of stimulation called SIS to see how they affect balance, movement, and strength in healthy, active adults.
GdanskAges 19–40 - NCT07522736Recruiting
Spinal anesthesia with dexmedetomidine for knee surgery
This trial tests adding dexmedetomidine (a calming medication) to bupivacaine (numbing medication) injected into the spine during knee surgery. The goal is to improve pain relief and recovery after surgery.
CairoAges 18–65
Common questions
- How many bones, joints & muscles clinical trials are recruiting?
- Clin2 is tracking 4,837 recruiting rheumatology & orthopedics studies from the U.S. registry right now, out of 7,953 we cover in this area in total.
- What does “Bones, joints & muscles” cover here?
- Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We group each study into bones, joints & muscles based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a bones, joints & muscles trial near me?
- Use the search to filter bones, joints & muscles studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.