Rheumatology & orthopedics
Bones, joints & muscles clinical trials
Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We’re tracking 4,837 recruiting studies in this area right now.
By phase
- Not applicable3,970
- Phase 2223
- Phase 4196
- Phase 1191
- Phase 3149
- Phase 1/Phase 275
- Phase 2/Phase 333
Top conditions
- Knee Osteoarthritis185
- Rheumatoid Arthritis142
- Fibromyalgia102
- Osteoporosis88
- Osteoarthritis74
- Osteoarthritis, Knee72
- Rheumatoid Arthritis (RA)65
- Shoulder Pain50
- Psoriatic Arthritis47
- Hip Osteoarthritis41
- Systemic Lupus Erythematosus41
- Duchenne Muscular Dystrophy39
- Degenerative Disc Disease38
- Total Knee Arthroplasty38
- Chronic Pain37
- Musculoskeletal Pain36
- Pain35
- Dermatomyositis31
Leading sponsors
- Riphah International University110
- Cairo University72
- Istituto Ortopedico Rizzoli71
- Assistance Publique - Hôpitaux de Paris37
- Foundation University Islamabad34
- Mayo Clinic29
- Massachusetts General Hospital27
- National Taiwan University Hospital25
- Chinese University of Hong Kong22
- Hacettepe University22
Where studies are running
- California211
- New York94
- Florida80
- Massachusetts76
- Arizona75
- Maryland73
- Texas65
- Alabama57
- Illinois54
- Pennsylvania50
Recruiting studies4,837 total
- NCT07150650Enrolling by invitation
Biomarkers for ICU weakness in children on breathing machines
This study looks for early warning signs (biomarkers) of muscle weakness that can happen in children who need a breathing machine for more than a few days. If your child is in the PICU on a ventilator for at least 3 days, this team may be able to test for clues that help prevent or manage this weakness.
Shanghai, Shanghai MunicipalityAges 1 month–18 years - NCT06649500Recruiting
Comparing two balance therapy methods for older adults
This trial tests whether a high-tech treadmill (Walker View) or group therapy works better for improving balance and preventing falls in older adults. It also uses artificial intelligence to predict fall risk early.
Rome, RomeAges 65 years+ - NCT06130956Recruiting
Vegan diet before knee replacement surgery study
This study compares a 2-week vegan diet to a regular diet before knee replacement surgery. It looks at how the diet affects protein turnover in the knee joint.
ArnhemAges 60–80 - NCT06319911Recruiting
Testing a new shoulder replacement implant system
This study tests a new shoulder implant system for people who need their first shoulder replacement due to arthritis or a shoulder deformity. It helps researchers see how well the implant works and if it improves shoulder function and pain.
San Francisco, CaliforniaAges 18 years+ - NCT06100445Recruiting
Exercise engagement in people over 60 at fall risk
This study looks at how to help people over 60 who are at risk of falling get more exercise. It focuses on falls caused by muscle or balance problems, and aims to improve engagement in physical activity.
Blackburn, LancashireAges 60–95 - NCT07294521RecruitingEarly Phase 1
Platelet-rich fibrin gel for chronic leg ulcers
This trial tests if a gel made from your own blood (platelet-rich fibrin) can help heal chronic leg ulcers that are not infected. It may be a good option if you have a long-lasting leg ulcer without signs of infection.
Rawalpindi, Punjab ProvinceAges 35 years+ - NCT07709819Recruiting
A second look inside the knee after surgery
This study looks inside your knee again after a previous surgery, using a very small camera to see how your knee has healed. It could help doctors learn more about how well these knee repairs work.
Las Vegas, NevadaAges 18 years+ - NCT07646899Recruiting
Unstable Loads and Shoulder Movement in Overhead Athletes
This study investigates how using unstable equipment (like a wobbly barbell) affects shoulder blade movement and muscle use during overhead pressing in athletes with shoulder impingement pain. The goal is to understand whether unstable loads might help improve shoulder mechanics and reduce pain in overhead athletes.
TaipeiAges 18–40 - NCT07641842Recruiting
Shoulder Surgery Nerve Block Pain Relief Study
This study looks at how well a single nerve-numbing injection (injected near nerves in your shoulder) works to control pain during outpatient arthroscopic shoulder surgery. Researchers want to understand your pain relief experience before, during, and after the procedure.
Toronto, OntarioAges 18 years+ - NCT07627308Recruiting
Ultrasound vs Fluoroscopy for Nerve Injections in Back Pain
This trial compares two imaging methods—ultrasound and fluoroscopy (X-ray)—to guide nerve injections for leg pain caused by compressed nerves in the lower back. The goal is to see which method is safer and more effective at relieving your pain.
Tanta, Gharbia GovernorateAges 18–75 - NCT07645859Recruiting
High-Intensity vs. Moderate Exercise for Chronic Lower Back Pain
This trial compares two types of exercise programs—one with short, intense bursts of activity and one with steady, moderate activity—to see which works better for people with long-lasting lower back pain that has no clear medical cause. You would participate in supervised exercise sessions over several weeks.
KarachiAges 20–48 - NCT07665801Recruiting
Foot exercises after hip replacement surgery
This trial tests whether doing special foot exercises can improve recovery in people who have had a total hip replacement. It might help with walking and balance.
Ankara, AltındağAges 50–80 - NCT07681661Recruiting
Massage Gun vs Deep Massage for Shoulder Knots
This study compares using a handheld massage device (like a massage gun) with deep pressure massage to treat painful knots in the upper shoulder muscle. It may help people with moderate to severe neck or shoulder pain who have not had recent treatment.
IslamabadAges 24–45 - NCT07623408Recruiting
Foot Position During Achilles Tendon Pain Recovery
This study tests whether the position of your foot during exercises affects how well your Achilles tendon heals and how much pain you experience. Researchers will compare different foot positions during rehabilitation to see which works best for reducing Achilles tendon pain and improving tendon strength.
Leuven, Vlaams-BrabantAges 18–65 - NCT07628361Recruiting
Strength Training on Uninjured Side During Shoulder Injury Recovery
This study tests whether exercising your uninjured arm and shoulder while your injured shoulder heals in a sling can help you recover strength and function faster. Researchers will also use a safe brain-imaging tool to measure how your nervous system responds to this training.
Santiago, ProvidenciaAges 18–36 - NCT07576296Recruiting
Shoulder exercises for rounded shoulders after pregnancy
This study tests whether specific shoulder blade exercises and stretches can help new mothers with rounded shoulders and shoulder discomfort. It aims to improve posture and reduce pain during the postpartum period.
Lahore, Punjab ProvinceAges 20–35 - NCT07578103Recruiting
Dairy vs Plant-based Yogurt for Weight and Bone Health
This study compares how dairy yogurt and plant-based yogurt affect weight, body composition, bone strength, and gut bacteria in postmenopausal women. It may help identify which type of yogurt is better for overall health during this life stage.
Québec, QuebecAges 40 years+ - NCT07587203Enrolling by invitation
Numbing medication for shoulder surgery and breathing
This trial compares two types of numbing medications (liposomal bupivacaine and standard bupivacaine) given as a nerve block for shoulder surgery. Researchers want to see which one works better for pain relief and causes fewer problems with your breathing afterward.
Nanjing, JiangsuAges 18–80 - NCT07605650Recruiting
Fascia Release Technique for Forward Head Posture
This study tests whether adding a specialized soft-tissue technique (IASTM) to standard physical therapy helps improve forward head posture better than therapy alone. Forward head posture is when your head juts forward, which can cause neck pain and stiffness.
Giza, Giza GovernorateAges 18–30 - NCT07589218Recruiting
Ankle Flexibility and Looseness in Young Basketball Players
This study measures how flexible your child's ankles are during weight-bearing activities and checks if loose ligaments (the bands that support joints) play a role. Researchers want to understand ankle flexibility in young basketball players aged 8–15 to help prevent injuries.
Valencia, ValenciaAges 8–15 - NCT07531537Recruiting
Breathing exercises versus neck muscle training for neck pain
This study compares two types of exercises—breathing exercises and deep neck muscle training—to see which works better for people with long-term neck pain. You'll do one type of exercise program to help relieve your pain and improve function.
ZagazigAges 18–35 - NCT07594444Recruiting
Whey Protein and Adaptogenic Supplements for Active Women
This study tests whether whey protein combined with adaptogenic herbs (natural stress-reducing supplements) can improve athletic performance and recovery in physically active women. You'll take supplements for several weeks while maintaining your normal training routine, and researchers will measure changes in your strength and fitness.
Brighton, East SussexAges 18–45 - NCT07557550Recruiting
Relaxation methods before orthopedic surgery: glasses vs. virtual reality
This study tests whether watching relaxing videos through special glasses or a virtual reality headset helps reduce anxiety before orthopedic surgery (like hip or knee replacement). Researchers want to see if these tools work better than no relaxation aid at all.
Amiens, PicardieAges 18 years+ - NCT07600437Recruiting
Muscle and Joint Problems in Musicians Study
This research study examines how common muscle, joint, and bone problems are among people who play musical instruments. Researchers will ask you questions and may do physical assessments to understand which musicians are most affected and why.
Multiple LocationsAges 18 years+
Common questions
- How many bones, joints & muscles clinical trials are recruiting?
- Clin2 is tracking 4,837 recruiting rheumatology & orthopedics studies from the U.S. registry right now, out of 7,953 we cover in this area in total.
- What does “Bones, joints & muscles” cover here?
- Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We group each study into bones, joints & muscles based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a bones, joints & muscles trial near me?
- Use the search to filter bones, joints & muscles studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.