Rheumatology & orthopedics
Bones, joints & muscles clinical trials
Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We’re tracking 4,610 recruiting studies in this area right now.
By phase
- Not applicable3,771
- Phase 2215
- Phase 4199
- Phase 1182
- Phase 3139
- Phase 1/Phase 270
- Phase 2/Phase 334
Top conditions
- Knee Osteoarthritis171
- Rheumatoid Arthritis131
- Fibromyalgia105
- Osteoporosis82
- Osteoarthritis71
- Rheumatoid Arthritis (RA)68
- Osteoarthritis, Knee65
- Shoulder Pain48
- Hip Osteoarthritis43
- Psoriatic Arthritis40
- Degenerative Disc Disease39
- Chronic Pain38
- Total Knee Arthroplasty38
- Systemic Lupus Erythematosus37
- Duchenne Muscular Dystrophy36
- Musculoskeletal Pain35
- Osteoarthritis (OA) of the Knee32
- Pain32
Leading sponsors
- Riphah International University85
- Istituto Ortopedico Rizzoli69
- Cairo University66
- Assistance Publique - Hôpitaux de Paris36
- Foundation University Islamabad31
- Mayo Clinic28
- Massachusetts General Hospital25
- National Taiwan University Hospital25
- Hacettepe University23
- Tanta University22
Where studies are running
- California207
- New York87
- Florida82
- Maryland76
- Arizona72
- Massachusetts71
- Texas66
- Alabama60
- Illinois51
- Pennsylvania48
Recruiting studies4,610 total
- NCT07373184Recruiting
Virtual planning for jaw joint replacement
This study looks back at past jaw joint (TMJ) replacement surgeries to see how virtual planning helped. If you already had this surgery at a specific hospital between 2010 and 2025, you might be included.
LundAges Any age - NCT07375290RecruitingPhase 1
Zoledronate for Bone Health After Stem Cell Transplant
This trial tests if a bone-strengthening medicine called zoledronate can help prevent bone problems in children and teens who have had a stem cell transplant. It may be an option for patients with low bone density or those who develop graft-versus-host disease after transplant.
Cincinnati, OhioAges 5–18 - NCT07375914Recruiting
New approach for managing acute low back pain in the ER
This trial tests a comprehensive program that looks at your physical, mental, and social needs to treat sudden low back pain in the emergency room. It may help you get better care and avoid long-term pain.
ParisAges 18–55 - NCT07377669Enrolling by invitation
Partial knee replacement plus ACL repair study
This study tests a combination surgery: repairing the torn ACL at the same time as replacing only the damaged part of your knee. It's designed for active people with arthritis in one knee compartment and a fully torn ACL.
BolognaAges 18–75 - NCT07371468RecruitingPhase 1
Study of an experimental drug for lupus, rheumatoid arthritis, and related conditions
This trial tests a new drug called GSK5926371 for people with certain autoimmune diseases that affect the joints, skin, and other tissues. It aims to see if the drug is safe and how well it works.
Buenos AiresAges 18–70 - NCT06837025Recruiting
Fascial manipulation for kids with cerebral palsy
This trial tests a hands-on technique called fascial manipulation to see if it improves movement and walking in children with cerebral palsy. It is for families living near Helsinki.
HelsinkiAges 7–14 - NCT05127980Recruiting
Study of immune antibodies after first-time EBV infection
This study looks at how the immune system’s antibodies behave after a first-time EBV infection, including whether they mistakenly react with the body’s own tissues. You might be offered a chance to help doctors understand why some people get longer or more intense symptoms from infectious mononucleosis.
BaselAges 18 years+ - NCT07367126Recruiting
Nerve pain in knee osteoarthritis: Pain and function study
This study looks at nerve-related pain in people with knee osteoarthritis and how it affects their pain level and daily function. It may help understand if nerve pain is a key factor in your knee OA symptoms.
IstanbulAges 40–70 - NCT06845696Recruiting
Comparing exercises vs. taping for forward head posture
This study compares two treatments—Brugger's relief exercises and kinesio taping—to see which one improves forward head posture better. Forward head posture means your head sits too far forward from your shoulders, which can cause neck strain.
Islamabad, FederalAges 20–40 - NCT07366424Recruiting
Testing new shoes to prevent falls in seniors
This trial is testing if special shoes called 'CHUT OTONOM®' can improve walking and reduce fall risk in older adults who have fallen before. It may help you find better balance and confidence.
LilleAges 65 years+ - NCT07367776Recruiting
Online education program for osteoporosis (RCT-PATOS)
This trial tests a digital education program for people with osteoporosis or osteopenia. It aims to help you learn more about your bone health and how to manage it, all from home using the 1177.se platform.
GävleAges 50 years+ - NCT07366099Recruiting
Special PET scan for tumor-induced osteomalacia
This trial tests a new PET/CT scan (using a tracer called Al18F-NOTA-LM3) to better find tumors causing TIO, a condition that leads to bone softening and weakness. It may help doctors diagnose and treat TIO more accurately.
Beijing, Beijing MunicipalityAges 18–80 - NCT07368751Recruiting
Vagus nerve stimulation for frozen shoulder treatment
This trial tests if stimulating the vagus nerve can help treat frozen shoulder. It might be an option if you have had shoulder pain and stiffness for at least 3 months and have not received prior treatment for this shoulder problem.
IstanbulAges 40–65 - NCT07367477Enrolling by invitation
Horizontal vs. vertical arm exercises for children with cerebral palsy
This study compares two types of arm and hand exercises (horizontal vs. vertical movements) for children with bilateral spastic cerebral palsy. It aims to see which type helps improve upper body function the most.
CairoAges 5–8 - NCT07367789Recruiting
Predicting recovery after knee replacement using smart insoles
This study uses special insoles to measure how you walk before and after a knee replacement. The goal is to see if these measurements can help predict how well you will recover after surgery.
Yongin-si, Gyeonggi-doAges 19 years+ - NCT07366736Recruiting
Cold and compression after knee replacement – a study
This study tests if a cooling and compression device applied to the knee after replacement surgery helps with pain and recovery. It compares the device to standard care in people having their first knee replacement.
ÉchirollesAges 18 years+ - NCT07368946Recruiting
Phosphate study for people with kidney disease
This study looks at how the body handles phosphate in people with chronic kidney disease. It may help researchers understand how to better manage phosphate levels to improve health.
Dallas, TexasAges 18 years+ - NCT07365033Recruiting
Exercise With Blood Flow Cuff vs Standard Training for Tennis Elbow
This study compares two exercise programs for long-term tennis elbow (pain for more than a year). One group does slow lowering exercises with a blood pressure cuff on the arm, and the other does standard resistance training.
Lahore, Punjab ProvinceAges 25–45 - NCT07365514RecruitingPhase 1
Blackcurrants study for bone health in postmenopausal women
This trial tests if taking a blackcurrant supplement can help maintain bone density and reduce osteoporosis risk in postmenopausal women. You will take daily capsules and provide blood, stool, and bone scan samples over the study period.
Storrs, ConnecticutAges 45–70 - NCT07362875Recruiting
Muscle imaging study for myotonic dystrophy
This study uses MRI scans to measure muscle changes in people with myotonic dystrophy (DM1 or DM2) and healthy volunteers. The goal is to find better ways to track the disease over time.
Winston-Salem, North CarolinaAges 18–65 - NCT07366827Recruiting
Motorized back support for low back pain
This trial tests a motorized lumbar support device to see if it can relieve non-specific lower back pain. It may help if your pain gets better with gentle stretching or pulling of the spine (called manual traction).
Québec, QuebecAges 18–65 - NCT07363876Recruiting
Ultrasound plus steroid injection for arthritis in limbs
This study tests whether using ultrasound (sound waves) before a steroid shot into the joint helps arthritis in the arms or legs. It's for people whose oral pain relievers haven't worked and who need a steroid injection.
TaichungAges 18 years+ - NCT07363980Enrolling by invitation
Heart CT Study for Rheumatoid Arthritis Patients
This study uses a special heart CT scan to look for early signs of heart disease in people with rheumatoid arthritis. It may help find problems before symptoms start.
AarhusAges 50–75 - NCT07369934Recruiting
Virtual reality vs. manual therapy for shoulder pain
This study compares virtual reality exercises with a hands-on therapy technique (Mulligan mobilization) to improve shoulder posture and function in people with subacromial impingement syndrome. It aims to find which approach may relieve pain and help you move better.
GizaAges 30–50
Common questions
- How many bones, joints & muscles clinical trials are recruiting?
- Clin2 is tracking 4,610 recruiting rheumatology & orthopedics studies from the U.S. registry right now, out of 7,508 we cover in this area in total.
- What does “Bones, joints & muscles” cover here?
- Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We group each study into bones, joints & muscles based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a bones, joints & muscles trial near me?
- Use the search to filter bones, joints & muscles studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.