Rheumatology & orthopedics
Bones, joints & muscles clinical trials
Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We’re tracking 4,610 recruiting studies in this area right now.
By phase
- Not applicable3,771
- Phase 2215
- Phase 4199
- Phase 1182
- Phase 3139
- Phase 1/Phase 270
- Phase 2/Phase 334
Top conditions
- Knee Osteoarthritis171
- Rheumatoid Arthritis131
- Fibromyalgia105
- Osteoporosis82
- Osteoarthritis71
- Rheumatoid Arthritis (RA)68
- Osteoarthritis, Knee65
- Shoulder Pain48
- Hip Osteoarthritis43
- Psoriatic Arthritis40
- Degenerative Disc Disease39
- Chronic Pain38
- Total Knee Arthroplasty38
- Systemic Lupus Erythematosus37
- Duchenne Muscular Dystrophy36
- Musculoskeletal Pain35
- Osteoarthritis (OA) of the Knee32
- Pain32
Leading sponsors
- Riphah International University85
- Istituto Ortopedico Rizzoli69
- Cairo University66
- Assistance Publique - Hôpitaux de Paris36
- Foundation University Islamabad31
- Mayo Clinic28
- Massachusetts General Hospital25
- National Taiwan University Hospital25
- Hacettepe University23
- Tanta University22
Where studies are running
- California207
- New York87
- Florida82
- Maryland76
- Arizona72
- Massachusetts71
- Texas66
- Alabama60
- Illinois51
- Pennsylvania48
Recruiting studies4,610 total
- NCT07360847Recruiting
Understanding recovery from rotator cuff shoulder pain with non-surgical care
This study looks at people with rotator cuff shoulder pain who are starting non-surgical treatments like physical therapy. It aims to understand which factors help people get better, so doctors can provide more personalized care.
LimerickAges 18 years+ - NCT07360093Recruiting
Nerve block for chronic hip pain from osteoarthritis
This study tests a nerve block treatment for people with long-term hip pain from osteoarthritis who haven't gotten enough relief from other treatments. It aims to see if this procedure can help reduce pain.
AnkaraAges 18–80 - NCT07356999Recruiting
Seeing and scoliosis: a visual perception study in teens
This study looks at how scoliosis may affect how you see and process visual information. It compares teens with scoliosis to teens without it to better understand any differences.
LyonAges 11–18 - NCT07357493Recruiting
Studying a new surgery for hand bone fractures
This trial tests a new way to fix certain broken hand bones (metacarpals) using a metal plate. It compares this method to other treatments to see which works better for healing and recovery.
Stockholm, Stockholm CountyAges 18 years+ - NCT07361198Recruiting
Knee artery embolization for arthritis pain
This trial tests a minimally invasive procedure to block small blood vessels in the knee, which may reduce pain from osteoarthritis. It's for people with ongoing knee pain even after standard treatments like medication or physical therapy.
Ústí nad LabemAges 40–80 - NCT07356206Recruiting
Dog-assisted therapy for fibromyalgia
This study tests whether spending time with a specially trained therapy dog can help people with fibromyalgia feel better and manage pain. You would attend 10 sessions and complete a few questionnaires.
GuimarãesAges 18 years+ - NCT07356674Recruiting
Surgery for Meniscus Tear with Mild Bow Legs
This trial tests a new surgical approach for a specific type of meniscus tear (the cartilage that cushions the knee) in people who have a mild bow-legged (varus) knee. It combines a small bone cut near the knee with arthroscopic repair to fix the tear.
Shenzhen, GuangdongAges 35–75 - NCT04031820Recruiting
Comparing two hip cup types to prevent dislocation
This trial compares a “dual-mobility” hip cup to a “unipolar” hip cup during primary hip replacement, focusing on dislocation (the hip coming out of place) and overall cost-effectiveness. It may help your care team choose the best implant for you and monitor outcomes after surgery.
AmsterdamAges 70 years+ - NCT04049279Recruiting
Testing hip implant cement amount for better stability
This study compares hip implant “migration” (how the implant may slowly shift) when a cemented hip cup is used with different cement approaches. It may help surgeons choose the option that keeps the implant more stable over time.
AmsterdamAges 65 years+ - NCT04851509Recruiting
Testing a special screw-locking nail for hip fractures
This trial studies a specific way of fixing certain hip (upper thigh) fractures using a metal nail with locking screws. It may help improve how well fractures heal and how stable the repair is.
New Westminster, British ColumbiaAges 18 years+ - NCT05111405Recruiting
Compare two surgeries for thumb CMC arthritis
This trial compares two different operations for thumb CMC (carpometacarpal) arthritis. It looks at which surgery works better when other non-surgery treatments have not helped you.
Calgary, AlbertaAges 50 years+ - NCT06503237Recruiting
SWK002 for tough-to-treat rheumatoid arthritis
This trial tests a new treatment called SWK002 for people with rheumatoid arthritis that hasn't improved after trying multiple medications. It aims to see if SWK002 can help when other treatments have failed.
Changsha, HunanAges 18 years+ - NCT06790628Recruiting
Rebuilding jaw symmetry with leg bone flap
This study compares two ways to rebuild a large missing section of your lower jaw using a piece of your own leg bone (called a fibula flap). The goal is to see which method creates better facial symmetry and a more natural result.
Cairo, Cairo GovernorateAges Any age - NCT06850194Recruiting
Comparing two jaw surgeries for severe underbite
This trial compares two surgical techniques to fix a severe underbite caused by a small lower jaw. One method uses a special cut in the jawbone and a piece of hip bone to lengthen it, while the other uses a different jawbone cut to move the jaw forward. It will help find which approach works better for people with this condition.
Beni-seuf, EgyptAges 18 years+ - NCT06853756Recruiting
Comparing two airway devices in children having orthopedic surgery
This trial compares two types of breathing tubes (I-gel and Ambu AuraGain) used during anesthesia to see which one causes less air to enter the stomach. It is for children ages 2-12 having planned orthopedic surgery.
Tanta, El-GharbiaAges 2–12 - NCT00874783Recruiting
Testing nerve-cell growth from donated body cells
This trial uses donated body cells or small hair samples from people with neurological diseases (and healthy donors) to try to grow “nerve-like” cells for research. It may help scientists learn how to better study and treat different neurological conditions.
Jerusalem, IsraelAges 18 years+ - NCT05006963Recruiting
Tele-rehab for jaw pain from TMJ problems
This trial tests a remote (telehealth) rehabilitation program to help reduce pain caused by temporomandibular joint (jaw joint) problems. It may help you if you’ve had facial/jaw-related pain for months and have a related diagnosis.
São PauloAges 18–60 - NCT06211062RecruitingPhase 2
Probiotics for chronic fatigue syndrome with IBS
This study tests whether a specific mix of probiotics can help people with chronic fatigue syndrome (ME/CFS) who also have irritable bowel syndrome (IBS). It's a small trial to see if improving gut health can ease symptoms.
Fort Lauderdale, FloridaAges 45–70 - NCT07348835Enrolling by invitation
Smart implant study for knee replacement recovery
This study compares two surgical methods for total knee replacement using a smart implant that tracks your recovery. It aims to see which approach helps people get back on their feet faster after surgery.
Sandy Springs, GeorgiaAges 18 years+ - NCT06856356Recruiting
Robot-assisted knee replacement surgery study
This study tests if robot-assisted total knee replacement surgery is safe and effective. It may help people who need knee replacement surgery by using advanced technology for more precise implant placement.
Hefei, AnhuiAges 18–80 - NCT07345949Recruiting
Study of skin inflammation in dermatomyositis
This trial looks at a type of skin inflammation called panniculitis that can happen in people with dermatomyositis. The goal is to learn more about this condition so that better treatments can be developed.
StrasbourgAges 1 year+ - NCT07348419Recruiting
Pain blocks after single-level lumbar disc surgery
This study compares two types of pain-blocking injections (Quadro-Iliac vs Thoracolumbar Interfascial Plane Block) to see which provides better pain relief after a single-level lumbar disc surgery. If you are having this surgery, the trial may help you have less pain and use fewer pain medicines afterwards.
SamsunAges 18–70 - NCT07348614RecruitingPhase 4
Knee manipulation: best numbing method for less pain
This study tests different numbing techniques to see which works best for pain during a knee manipulation procedure. It may help you have less pain and a smoother recovery.
Durham, North CarolinaAges 18–75 - NCT07344727Recruiting
Can haskap berries help you recover after heavy squats?
This study tests whether taking haskap berries (a type of superfruit) before and after intense squat workouts can speed up your recovery and reduce soreness.
Bozeman, MontanaAges 18–35
Common questions
- How many bones, joints & muscles clinical trials are recruiting?
- Clin2 is tracking 4,610 recruiting rheumatology & orthopedics studies from the U.S. registry right now, out of 7,508 we cover in this area in total.
- What does “Bones, joints & muscles” cover here?
- Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We group each study into bones, joints & muscles based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a bones, joints & muscles trial near me?
- Use the search to filter bones, joints & muscles studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.