Rheumatology & orthopedics
Bones, joints & muscles clinical trials
Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We’re tracking 4,837 recruiting studies in this area right now.
By phase
- Not applicable3,970
- Phase 2223
- Phase 4196
- Phase 1191
- Phase 3149
- Phase 1/Phase 275
- Phase 2/Phase 333
Top conditions
- Knee Osteoarthritis185
- Rheumatoid Arthritis142
- Fibromyalgia102
- Osteoporosis88
- Osteoarthritis74
- Osteoarthritis, Knee72
- Rheumatoid Arthritis (RA)65
- Shoulder Pain50
- Psoriatic Arthritis47
- Hip Osteoarthritis41
- Systemic Lupus Erythematosus41
- Duchenne Muscular Dystrophy39
- Degenerative Disc Disease38
- Total Knee Arthroplasty38
- Chronic Pain37
- Musculoskeletal Pain36
- Pain35
- Dermatomyositis31
Leading sponsors
- Riphah International University110
- Cairo University72
- Istituto Ortopedico Rizzoli71
- Assistance Publique - Hôpitaux de Paris37
- Foundation University Islamabad34
- Mayo Clinic29
- Massachusetts General Hospital27
- National Taiwan University Hospital25
- Chinese University of Hong Kong22
- Hacettepe University22
Where studies are running
- California211
- New York94
- Florida80
- Massachusetts76
- Arizona75
- Maryland73
- Texas65
- Alabama57
- Illinois54
- Pennsylvania50
Recruiting studies4,837 total
- NCT07297758Recruiting
Shoulder muscle activity during extension exercises
This study looks at how a specific back muscle works when you do shoulder exercises. It may help find better ways to strengthen the shoulder.
Ankara, SamandagAges 18–40 - NCT07302958Recruiting
Comparing remote, in-person, and mixed exercise for neck pain
This trial compares three ways to treat chronic neck pain: doing exercises at home with remote guidance, doing them in a clinic with a therapist, or a mix of both. It aims to find which method works best for people with ongoing neck pain.
CairoAges 20–45 - NCT07243327Recruiting
Shockwave therapy vs standard rehab for hip pain
This trial compares two treatments—shockwave therapy and conventional physical therapy—for long-lasting pain on the outside of the hip, often called trochanteric pain syndrome. It aims to find which option works better for people whose hip pain has persisted for months.
IstanbulAges 18–65 - NCT07252804RecruitingPhase 4
Testing the MenB vaccine safety and immune response in children with rheumatic disease
This trial tests a meningitis B vaccine (MenB-4C) in children and young adults with autoimmune rheumatic diseases. It aims to see if the vaccine is safe and works well for these patients.
São Paulo, São PauloAges 2–25 - NCT07251361Enrolling by invitation
Exercise program for heart failure with preserved ejection fraction
This study tests whether a special exercise program that combines different types of training (like aerobic, strength, and balance) can improve heart and muscle function, daily abilities, and quality of life in people with heart failure with preserved ejection fraction (HFpEF). You may benefit if your heart failure is stable and you are able to exercise safely.
Pamplona, NavarreAges 18 years+ - NCT07254494Recruiting
Bone Regrowth Guide for Lower Jaw Implants
This study tests two types of membranes used to grow bone in the lower jaw before placing dental implants. Participation lasts about one year and involves a bone-regrowth procedure to prepare for implants.
BeirutAges 18–80 - NCT07212049Enrolling by invitation
Ultrasound to measure magnetic growing rods
This study tests if ultrasound can accurately measure the length of magnetically controlled growing rods used in leg bone lengthening. It may help doctors monitor treatment without extra X-rays.
Orlando, FloridaAges 8–21 - NCT07250126Recruiting
3D printed spine model for spinal surgery
This trial is testing a new 3D-printed model of the spine to help plan surgeries. It may offer a more personalized approach to spine care.
Milan, MIAges 30–70 - NCT07208448Recruiting
Study on a new shoulder spacer for torn rotator cuff
This trial tests a new biodegradable spacer for the shoulder in people with a full-thickness rotator cuff tear. It may help relieve pain and improve shoulder function without the need for more invasive surgery.
AshdodAges 50 years+ - NCT07233993Recruiting
Ultrasound-guided vs. standard Botox injections for cervical dystonia
This trial compares using ultrasound to guide Botox injections versus the usual method without ultrasound, to see if it improves outcomes for people with cervical dystonia.
MilanAges 18 years+ - NCT07243535Recruiting
Rhythm training for athletes after ACL surgery
This study compares two types of rhythm-based training (fractal vs isochronous cueing) to see which helps athletes regain better movement after ACL reconstruction. If you're an athlete who had ACL surgery less than two years ago and are now pain-free walking, you may be able to join.
Almada, Monte de CaparicaAges 15–35 - NCT07242300RecruitingPhase 3
Testing a new botulinum toxin for arm stiffness after stroke
This trial tests a new injectable medication (Eveotox) to see if it can safely reduce arm or hand stiffness in people who have had a stroke. The goal is to improve daily activities like dressing or cleaning your hand.
Beijing, Beijing MunicipalityAges 18–80 - NCT07260318Enrolling by invitation
How fast bowling affects bone health
This study looks at how cricket fast bowling affects your bone health and the signals your body sends to build or break down bone. If you're a healthy young male fast bowler, this trial will help understand the immediate impact of bowling on your bones.
Loughborough, LeicestershireAges 18–30 - NCT07232511Recruiting
Cuff-assisted exercise for shoulder pain
This study tests whether using a blood pressure cuff during gentle shoulder exercises can help reduce pain and improve movement. It is for people with ongoing shoulder pain related to the rotator cuff (the muscles and tendons that help lift and rotate your arm).
Valencia, ValenciaAges 18–65 - NCT07241559Recruiting
Low back pain treatment study: injection and mobilization
This study tests two treatments for chronic low back pain: a special injection of dextrose (a sugar solution) guided by ultrasound, and a technique to mobilize the fascia (connective tissue) in the lower back. It aims to see if these help people who haven't found relief from standard treatments.
Ankara, AltındağAges 18–65 - NCT07204288Recruiting
Lumbar and sacroiliac fusion study for people with previous implants
This study looks at how well certain Spinal Simplicity implants work over time for people who have already received them. You must have received a specific implant between 2022 and 2025 to qualify.
Overland Park, KansasAges 18 years+ - NCT07219498Recruiting
Probiotics for muscle soreness after exercise
This trial tests whether taking a probiotic supplement for 5 weeks can reduce muscle soreness after exercise. If you exercise regularly and are generally healthy, you may be able to join.
Minneapolis, MinnesotaAges 18–30 - NCT07125794Recruiting
Brace comparison for children with relapsed clubfoot
This trial tests whether a modified version of the Denis Brawn brace works better than the original for treating relapsed clubfoot in young children who were previously treated with the Ponseti casting method.
CairoAges 2–5 - NCT07256769Recruiting
Vitamin K, D-chiro inositol and α-lactalbumin for bone health
This trial tests a combination of vitamin K, D-chiro inositol, and α-lactalbumin to help maintain bone strength in women with breast cancer who are on hormone therapy and have low vitamin D. It aims to see if these supplements improve bone health while you take a standard bone medication (alendronate).
Latina, ItalyAges 35–70 - NCT07166328Recruiting
Body Image and Spine Curvature in Scoliosis
This study looks at how teenagers with scoliosis see their own body shape and posture. It may help doctors understand how scoliosis affects self-image and movement.
New Cairo, Cairo GovernorateAges 11–18 - NCT07104370Recruiting
Comparing freeze-dried donor bone vs. your own bone for jaw grafting
This trial compares two types of bone graft materials for rebuilding the jawbone so you can later get dental implants. One is a freeze-dried bone from a donor (allograft), and the other is a small piece of your own bone (autograft).
Budapest, HungaryAges 18 years+ - NCT07141017Recruiting
Global evaluation study for recent axial spondyloarthritis
This study is for people recently diagnosed with axial spondyloarthritis (a type of inflammatory arthritis affecting the spine). It tests whether a standardized global review and education program can help patients better understand and manage their condition.
BesançonAges 18–80 - NCT07133724Recruiting
Digital health study for lumbar spine wear and tear
This study uses digital tools to measure how lumbar degeneration affects walking. It aims to find early signs of spine problems in people without current back pain.
TaipeiAges 50–80 - NCT07132736Recruiting
Underwater vs. regular exercise for quality of life and muscle power
This trial compares exercising underwater to doing regular aerobic exercise on land. It aims to see which type of exercise better improves muscle strength, energy levels, and overall quality of life in people with excess weight.
AmmanAges 18–50
Common questions
- How many bones, joints & muscles clinical trials are recruiting?
- Clin2 is tracking 4,837 recruiting rheumatology & orthopedics studies from the U.S. registry right now, out of 7,953 we cover in this area in total.
- What does “Bones, joints & muscles” cover here?
- Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We group each study into bones, joints & muscles based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a bones, joints & muscles trial near me?
- Use the search to filter bones, joints & muscles studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.