Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,407 recruiting studies in this area right now.
By phase
- Not applicable9,742
- Phase 2782
- Phase 1577
- Phase 3534
- Phase 4342
- Phase 1/Phase 2307
- Phase 2/Phase 3123
Top conditions
- Stroke843
- Parkinson Disease429
- Alzheimer Disease342
- Multiple Sclerosis342
- Dementia226
- Ischemic Stroke200
- Epilepsy197
- Obstructive Sleep Apnea156
- Spinal Cord Injuries153
- Insomnia152
- Sarcopenia150
- Traumatic Brain Injury150
- Acute Ischemic Stroke138
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Migraine114
- Pain Management113
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic98
- Xuanwu Hospital, Beijing93
- VA Office of Research and Development92
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California680
- Massachusetts299
- New York292
- Florida274
- Texas267
- Maryland246
- Arizona213
- Alabama209
- Illinois189
- Pennsylvania177
Recruiting studies12,405 total
- NCT05951764Recruiting
Checking risk prediction for heart and brain conditions
This study builds or tests computer models that predict risk for heart (cardiovascular) and thinking/memory (neurocognitive) problems using information from people in the general population. It may help improve early detection and planning for care.
ParisAges 45 years+ - NCT05949047Recruiting
Phone-based training for family caregivers of Alzheimer’s patients
This study tests a smartphone program that teaches skills to better manage emotions for people who provide unpaid care for someone with Alzheimer’s disease. It may help caregivers feel less overwhelmed and cope more effectively during daily stress.
Houston, TexasAges 18 years+ - NCT06030310Recruiting
Motor program effects on brain development in children
This trial tests if a special exercise program can help with brain development in kids ages 7 to 9. It may support how their nerves and muscles work together.
Manresa, BarcelonaAges 7–9 - NCT06019637Recruiting
Long-term safety study of Zolgensma for spinal muscular atrophy
This study follows the long-term safety of Zolgensma gene therapy in Brazilian children with spinal muscular atrophy (SMA). It helps doctors understand how safe the treatment is over time.
Curitiba, ParanáAges birth–100 years - NCT05947279Recruiting
Testing noninvasive brain stimulation to study motor control
This study uses noninvasive brain stimulation and related tasks (and may include virtual reality) to understand how the brain controls movement. It may help researchers learn more about motor control, which can guide future treatments.
Richmond, VirginiaAges 18–40 - NCT05975697Recruiting
Electrical stimulation after thrombectomy for arm paralysis
This study tests whether a special electrical stimulation therapy can improve arm movement, physical activity, and quality of life after a thrombectomy. You may be considered if you are an adult with arm paralysis and can communicate after your procedure.
Adana, YüreğirAges 18 years+ - NCT05662111RecruitingPhase 2
Etidronate treatment for brain calcifications in Fahr disease
This Phase 2 study tests whether etidronate (a medicine that affects bone-calcium handling) can help people with Fahr disease or a similar condition marked by calcium deposits in the brain. It will also check safety and whether certain tests can track changes over time.
Utrecht, UtrechtAges 18 years+ - NCT05859126Enrolling by invitation
Choline supplement study on teens’ learning and thinking
This study follows children of mothers who previously took a choline supplement, and it tests how those children think and learn when they reach age 13. It looks at whether earlier choline intake during pregnancy is linked to better or different thinking skills in adolescence.
Ithaca, New YorkAges 13–13 - NCT05740839Recruiting
High-intensity exercise program for young brain tumor survivors
This pilot study tests whether a high-intensity interval exercise routine is safe and doable for young adult survivors of pediatric brain tumors. It may help you improve fitness and quality of life while researchers closely monitor safety.
Boston, MassachusettsAges 18–45 - NCT05888064Recruiting
Imaging-guided personalized radiation for skull-base chordoma
This trial studies how detailed imaging can guide personalized (custom) radiation treatment for skull-base chordoma. It may help doctors plan treatment more accurately using measurements taken before and during therapy.
Pavia, PvAges 18 years+ - NCT05910619Recruiting
Noninvasive brain stimulation to support memory and thinking
This study tests a noninvasive way of stimulating the brain to see if it can help older adults with typical age-related changes or mild memory problems. You may be invited if your screening tests and health history fit one of their target groups.
Gainesville, FloridaAges 65–84 - NCT05868525RecruitingPhase 4
Compare two aspirin doses after blunt vessel injury
This trial tests whether taking a lower-dose aspirin (81 mg) works as well as a higher-dose aspirin (325 mg) to prevent stroke after a blunt injury that affects blood vessels in the neck/head. It may help some patients lower their stroke risk with the simplest, safest dose.
Loma Linda, CaliforniaAges 18 years+ - NCT05806450Recruiting
Sleep training for parents and babies using online sessions
This trial tests an online sleep program meant to improve sleep for parents and young children. It may help families that want better nighttime routines and sleep quality for babies aged 6 to 24 months.
SeoulAges 6 months–2 years - NCT05816603RecruitingPhase 2
Stimulation treatment to help post-stroke fatigue
This Phase 2 study tests whether gentle electrical stimulation of the brain can reduce fatigue after a stroke. It may help people who are still bothered by significant tiredness at least 3 months after their stroke.
New York, New YorkAges 18 years+ - NCT05721261Recruiting
Electrical stimulation to help a newly injured nerve heal
This trial is testing whether temporary electrical stimulation can help regenerate, or regrow, a nerve after an acute (recent) injury. It may be relevant if you have a new peripheral nerve injury, but it likely would not be for people with peripheral neuropathy or certain implanted devices.
Gainesville, FloridaAges 18–65 - NCT05757609Recruiting
Brain stimulation therapy for chronic low back pain
This trial tests whether a non-invasive brain stimulation treatment can improve physiotherapy results for people with long-lasting low back pain. You may be asked to do questionnaires and follow a treatment plan, and some people may be able to reduce pain or improve function.
GenevaAges 18–65 - NCT05714007RecruitingPhase 4
Iron infusion for anemia after spinal deformity surgery
This trial looks at whether a specific iron infusion (ferric derisomaltose) can help treat anemia after spinal deformity surgery. You may be eligible if your blood counts show anemia soon after surgery and it’s likely due to iron deficiency.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05792930Recruiting
Therapy plus biofeedback for body-symptom distress
This study tests an integrated talk-therapy program that combines cognitive-behavioral therapy and biofeedback to help people whose symptoms are strongly felt in the body. It may help by teaching skills to reduce distress and improve how you manage symptoms.
YunlinAges 20–70 - NCT05711082Recruiting
Testing brain monitoring and dopamine in healthy adults
This study tests how the brain responds during monitoring tasks related to dopamine (a brain chemical involved in movement and motivation). It’s meant for healthy volunteers, so you may help researchers understand how dopamine-related signals work in real time.
BronAges 18–45 - NCT05847270Recruiting
Surgery for a neck bone dislocation that can’t be put back
This study looks at surgical treatment for a specific type of neck bone dislocation that cannot be corrected without surgery. It may help patients whose imaging and traction testing show they need an operation to stabilize the neck.
Beijing, Beijing MunicipalityAges Up to 80 years - NCT05880342RecruitingPhase 3
Study how the brain affects fatigue after exercise
This trial studies how your brain responds when you feel mentally and physically tired, using trained healthy volunteers. It may help researchers understand fatigue better, which could guide future treatments for people who struggle with fatigue.
Brussels, Brussels CapitalAges 18–35 - NCT05694663Recruiting
Vagus nerve stimulation to aid stroke recovery
This registry looks at people with a prior ischemic stroke to see how a device that stimulates the vagus nerve may support arm recovery. If you are planning to get the implant and can follow the program steps, your information may be followed to track progress and safety.
New York, New YorkAges 18 years+ - NCT05885646Recruiting
Sulthiame study using sleep EEG in children with epilepsy
This trial tests whether sulthiame changes sleep-related brain wave activity (EEG) in children with certain epilepsy syndromes. It may help doctors understand how sulthiame affects the brain’s electrical patterns between seizures.
AngersAges 6–15 - NCT05708105Recruiting
Testing ultrasound and near-infrared light to predict brain bleeding
This study looks at using two noninvasive tools on very preterm newborns to better predict whether an intraventricular hemorrhage (bleeding in the brain’s fluid spaces) may happen. If successful, it could help doctors spot risk earlier and monitor or treat babies sooner.
Calgary, AlbertaAges Any age
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,407 recruiting neurology studies from the U.S. registry right now, out of 19,276 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.