Oncology
Cancer clinical trials
Studies of cancers and tumors of every type and site, from prevention to treatment. We’re tracking 20,669 recruiting studies in this area right now.
By phase
- Not applicable9,830
- Phase 24,462
- Phase 12,741
- Phase 1/Phase 21,687
- Phase 31,405
- Phase 2/Phase 3281
- Phase 4263
Top conditions
- Breast Cancer1,229
- Cancer659
- Prostate Cancer657
- Colorectal Cancer496
- Lung Cancer428
- Ovarian Cancer338
- Multiple Myeloma329
- Gastric Cancer300
- Pancreatic Cancer296
- Acute Myeloid Leukemia293
- Hepatocellular Carcinoma284
- Solid Tumor258
- Advanced Solid Tumor256
- Cervical Cancer232
- Head and Neck Cancer229
- Endometrial Cancer205
- Advanced Solid Tumors195
- Esophageal Cancer193
Leading sponsors
- M.D. Anderson Cancer Center451
- Fudan University311
- Memorial Sloan Kettering Cancer Center289
- Sun Yat-sen University289
- National Cancer Institute (NCI)288
- Mayo Clinic238
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences151
- City of Hope Medical Center144
- AstraZeneca132
- University Health Network, Toronto125
Where studies are running
- California1,425
- Texas641
- Arizona513
- Florida446
- Alabama420
- New York412
- Massachusetts340
- Maryland328
- New Jersey268
- Pennsylvania241
Recruiting studies20,669 total
- NCT05447923Recruiting
Colorectal screening study for Black and underserved Phoenix adults
This study aims to help improve colorectal cancer screening (checking the colon) in Black and underserved communities in Phoenix. It may help you find out which screening tests fit you and encourage regular screening.
Scottsdale, ArizonaAges 45 years+ - NCT05448365Recruiting
Vitamins and plant compounds for uterine fibroid symptoms
This trial studies whether a combination of vitamin D, epigallocatechin gallate (a plant compound), D-chiro-inositol, and vitamin B6 can improve symptoms from uterine fibroids. It may help by reducing symptoms such as heavy or irregular bleeding and pelvic pain in people who can undergo surgery.
Francavilla Fontana, ApuliaAges 30–40 - NCT05447988Recruiting
Breast reconstruction study using a new tissue expander
This trial studies a new device used during breast reconstruction after mastectomy, usually to stretch skin before placing a breast implant. It may help people who’ve had breast cancer and completed radiation at least a year ago by improving the reconstruction process and tracking outcomes.
RancaguaAges 18 years+ - NCT05449691Recruiting
Compare natural tissue samples with synthetic mesh in breast reconstruction
This study looks at how “biological” materials compare with synthetic mesh during immediate, one-stage breast reconstruction after mastectomy. It may help doctors choose the best support material to improve reconstruction outcomes for women undergoing this surgery.
DerbyAges 18 years+ - NCT05450016Recruiting
Using photos and a computer to assess breast appearance after treatment
This study uses a computer (deep neural network) to judge how the breast looks after breast-conserving surgery or full breast reconstruction and radiation therapy. It may help doctors measure cosmetic results more consistently using photographs.
Mumbai, MaharashtraAges 19–80 - NCT05450029RecruitingPhase 2
Adding immunotherapy to chemo-radiation for rectal cancer
This Phase 2 trial studies whether adding sintilimab (an immunotherapy drug) to standard chemo-radiation before surgery can improve outcomes for people with locally advanced rectal cancer. It’s aimed at tumors with certain immune “signature” scores and specific cancer stage features.
Guangzhou, GuangdongAges 18–75 - NCT05450835Recruiting
Surgery technique comparison for stomach cancer near the esophagus
This study compares two ways surgeons reconnect the digestive tract after removing the whole stomach for certain stomach cancers near the esophagus. It aims to see which technique is safer and leads to better recovery and outcomes.
Quanzhou, FujianAges 18–75 - NCT05451043RecruitingPhase 2
Durvalumab and tremelimumab plus chemotherapy with propranolol
This Phase 2 study tests whether adding propranolol to durvalumab and tremelimumab along with chemotherapy can help control advanced pancreatic cancer, liver cancer, or bile duct cancer. It aims to shrink tumors and help people live longer or feel better when the cancer can’t be cured with surgery or local treatment.
Edmonton, AlbertaAges 18 years+ - NCT05450965RecruitingPhase 2
Onvansertib for relapsed small cell lung cancer
This trial studies onvansertib, a targeted medicine, in people whose small cell lung cancer has come back or did not respond to prior platinum chemotherapy. It aims to shrink tumors and improve outcomes after standard treatment has already been tried.
Baltimore, MarylandAges 18 years+ - NCT05452005RecruitingPhase 1
PET scan with a new tracer for lung cancer brain metastases
This Phase 1 study tests whether a specialized PET scan tracer can “light up” metastatic non-small cell lung cancer in the brain. If you join, you’ll get brain MRI and PET/CT scans and you’ll continue with your planned cancer treatments and follow-up imaging.
Sacramento, CaliforniaAges 18 years+ - NCT05451303Recruiting
Testing for oral and throat cancer risk with a mouth test
This trial studies how well an at-home or clinic mouth test (OralViome Cancer Testing System) can detect signs of risk for oral or throat cancer. You may benefit by getting cancer-risk testing if you are considered high risk, though results will guide whether further evaluation is needed.
New York, New YorkAges 18 years+ - NCT05451784RecruitingPhase 1/Phase 2
PD-1 TIL therapy for advanced triple-negative breast cancer
This study tests an immune-cell treatment made from your tumor tissue. It aims to help people with advanced or metastatic triple-negative breast cancer by collecting PD-1–positive immune cells and giving them back after treatment.
BarcelonaAges 18 years+ - NCT05451901Recruiting
Direct surgery versus step-by-step drainage for walled pancreatic infection
This study compares two ways to treat a pancreatic infection pocket (walled-off necrosis): removing dead/infected tissue right away versus starting with drainage and escalating if needed. It may help find the safest, most effective approach for getting the infection under control.
Bunkyō-Ku, TokyoAges 18 years+ - NCT05451979Recruiting
Exercise training at home for kids after heart transplant
This trial tests a home-based, short bursts exercise program (HIIT using the MedBIKE™ system) for children who had a heart transplant at least 6 months ago. It may help improve fitness and safety after transplant, while checking which kids can participate without heart rhythm or symptom problems.
Edmonton, AlbertaAges 10–18 - NCT05452213RecruitingPhase 4
Study patterns of ribociclib response and resistance in breast cancer
This trial looks at how well ribociclib works and why it may stop working over time in people with advanced, hormone-receptor–positive, HER2-negative breast cancer. It also analyzes blood and tissue samples to help researchers understand resistance patterns and improve future treatment decisions.
Erlangen, BavariaAges 18 years+ - NCT05453682Recruiting
Radiation plus chemotherapy to preserve the bladder
This study tests whether a shorter, more focused radiation plan given at the same time as chemotherapy can control muscle-invasive bladder cancer while keeping the bladder. You may be offered bladder-preserving treatment if your cancer stage and health conditions fit the study rules.
SeoulAges 20 years+ - NCT05454280RecruitingPhase 3
Manage surgical risk after high-risk cancer operations
This study looks at a “risk-based plan” to help guide care after major cancer surgery, aiming to improve recovery and outcomes. You may be in the study when you’re about to have elective (planned) high-risk cancer surgery and then again just before hospital discharge.
Philadelphia, PennsylvaniaAges 18 years+ - NCT05454488RecruitingPhase 2
Study focal freezing for intermediate-risk prostate cancer
This trial tests whether freezing only the cancer area in the prostate (focal cryotherapy) can control intermediate-risk prostate cancer. It aims to limit treatment to one tumor focus while closely checking results with targeted and follow-up testing.
Houston, TexasAges 18 years+ - NCT05455619RecruitingPhase 1/Phase 2
Targeted drugs for PI3K-altered, HR+/HER2- breast cancer
This Phase 1/2 trial tests how well a combination of targeted medicines works for advanced or returning HR+/HER2- breast cancer that has a PI3K pathway change (such as PIK3CA, PTEN, or AKT1). It may help by blocking growth signals in the cancer and is especially for people whose cancer has progressed after hormone therapy and a CDK4/6 inhibitor.
Loma Linda, CaliforniaAges 18 years+ - NCT05456841Recruiting
Empathic communication training for lung cancer care
This trial tests whether training healthcare providers in empathetic communication improves their interactions with people receiving lung cancer care. You may be invited because your doctor’s clinic is participating and you meet the patient and language requirements.
Irvine, CaliforniaAges 18–100 - NCT05456256RecruitingPhase 2
LP-300 plus chemo for lung cancer in never-smokers
This Phase 2 trial tests LP-300 with carboplatin and pemetrexed to treat advanced lung adenocarcinoma in people who have never smoked. It may help shrink tumors and slow the disease in a specific genetic group of lung cancer.
Beverly Hills, CaliforniaAges 18 years+ - NCT05457595Recruiting
Re-irradiation for pelvic and groin cancer recurrences
This study tests giving radiation again to treat a cancer that has returned in the pelvic area (including the groin) when surgery isn’t a good option. It may help control the tumor while trying to protect nearby organs such as the small intestine.
Pavia, PvAges 18 years+ - NCT05457829RecruitingPhase 2
Testing two chemotherapy combinations for relapsed pediatric rhabdomyosarcoma
This trial compares two treatment combinations—liposomal doxorubicin plus irinotecan versus a different chemotherapy plan—in children and teens whose rhabdomyosarcoma came back or did not respond. It aims to see which option works better and is safer for children who have had prior cancer treatment.
GuangzhouAges 6 months–18 years - NCT05460507RecruitingPhase 1
Re-treating brain tumor with radioactive liposome after prior dose
This Phase 1 trial tests whether a radioactive treatment delivered in tiny fat “packets” is safe and tolerable when given again to people whose glioma (brain tumor) came back after a previous similar treatment. It also looks at how well this re-treatment works in carefully selected patients.
San Antonio, TexasAges 18 years+
Common questions
- How many cancer clinical trials are recruiting?
- Clin2 is tracking 20,669 recruiting oncology studies from the U.S. registry right now, out of 31,797 we cover in this area in total.
- What does “Cancer” cover here?
- Studies of cancers and tumors of every type and site, from prevention to treatment. We group each study into cancer based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a cancer trial near me?
- Use the search to filter cancer studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.