Gastroenterology
Digestive system clinical trials
Conditions of the stomach, intestines, liver, and the rest of the digestive tract. We’re tracking 7,606 recruiting studies in this area right now.
By phase
- Not applicable4,686
- Phase 21,188
- Phase 1568
- Phase 3457
- Phase 1/Phase 2368
- Phase 4229
- Phase 2/Phase 3110
Top conditions
- Colorectal Cancer479
- Pancreatic Cancer287
- Gastric Cancer283
- Hepatocellular Carcinoma256
- Esophageal Cancer189
- Rectal Cancer168
- Breast Cancer146
- Crohn Disease134
- Ulcerative Colitis129
- Hepatocellular Carcinoma (HCC)114
- Colon Cancer112
- Liver Cancer99
- Lung Cancer95
- Inflammatory Bowel Diseases94
- Pancreas Cancer91
- Ovarian Cancer89
- Esophageal Squamous Cell Carcinoma86
- Cystic Fibrosis77
Leading sponsors
- Fudan University101
- Sun Yat-sen University85
- Mayo Clinic75
- Chinese University of Hong Kong56
- Second Affiliated Hospital, Zhejiang University, School of Medicine56
- M.D. Anderson Cancer Center55
- Assistance Publique - Hôpitaux de Paris53
- Sixth Affiliated Hospital, Sun Yat-sen University51
- National Cancer Institute (NCI)49
- National Taiwan University Hospital45
Where studies are running
- California438
- Arizona190
- Texas140
- Alabama129
- Florida128
- New York120
- Massachusetts119
- Maryland88
- Ohio79
- Illinois69
Recruiting studies7,606 total
- NCT07235215Recruiting
Testing Vivatlac for Irritable Bowel Syndrome
This study tests a product called Vivatlac to see if it can help people with Irritable Bowel Syndrome (IBS). If you have moderate-to-severe IBS and haven't taken probiotics or antibiotics recently, you may be able to join.
JarocinAges 18–65 - NCT07235228Recruiting
Synbiotic supplement for irritable bowel syndrome
This trial tests whether a synbiotic (a mix of probiotics and prebiotics) called Vivatlac can improve gut health in people with moderate to severe irritable bowel syndrome (IBS). If you have IBS and are not already taking probiotics or antibiotics, you may be able to join.
JarocinAges 18–65 - NCT07239245RecruitingPhase 2
TACE plus immunotherapy for high-risk liver cancer before surgery
This trial tests whether a combination of two therapies—targeted chemotherapy delivered directly to the liver (TACE) plus immunotherapy (atezolizumab) and a targeted drug (bevacizumab)—can keep liver cancer from coming back after surgery. It is for people whose tumors can be surgically removed but are at high risk of recurrence.
Beijing, Beijing MunicipalityAges 18–75 - NCT07230379Recruiting
Comparing two treatments for first-time uncomplicated appendicitis
This trial tests a newer, less invasive procedure called ERAT against standard laparoscopic appendectomy for adults with a first episode of uncomplicated appendicitis. The goal is to see which approach works better with fewer risks.
Chongqing, ChingqingAges 18 years+ - NCT07238985RecruitingPhase 1/Phase 2
Cilostazol for treating nonalcoholic fatty liver disease
This study tests whether a medicine called cilostazol can help treat nonalcoholic fatty liver disease. It is for adults who have fatty liver seen on an ultrasound and do not have other liver problems.
Damietta, New DamiettaAges 18–60 - NCT07239076Recruiting
Buttock muscle surgery for bowel control
This trial tests a surgery that uses a muscle from your buttock to help control bowel leakage. It is for people with severe bowel incontinence that has not improved with other treatments.
Asyut, UniversityAges 9–70 - NCT07237516Recruiting
Study of Zymfentra for people with Crohn's or colitis
This study follows adults with inflammatory bowel disease who are starting or switching to Zymfentra. Researchers will track your health over the next year to see how the medicine works in real life.
New Haven, ConnecticutAges 18 years+ - NCT07235410Recruiting
Body composition study for liver cancer patients having TACE
This trial uses deep learning to analyze body composition from scans in people with hepatocellular carcinoma (HCC) who are undergoing TACE (a treatment that blocks blood flow to the tumor). It aims to predict outcomes better and may help doctors tailor care.
Wuhan, HubeiAges 18 years+ - NCT07238309Recruiting
Comparing two ways to reinforce stomach stapling during gastric bypass
This trial tests two methods—oversewing stitches versus surgical clips—to lower the chance of bleeding after a type of gastric bypass surgery called one anastomosis gastric bypass. If you qualify, you may help find the safest technique.
Cairo, Cairo GovernorateAges 18–80 - NCT07231601Recruiting
Laparoscopic surgery for Crohn's disease of the small intestine
This trial tests a specific laparoscopic (keyhole) surgery technique for Crohn's disease affecting the last part of the small intestine. It aims to see if removing more of the fatty tissue around the bowel leads to better outcomes. If you have Crohn's disease needing surgery in this area, you may be eligible.
Piraeus, AtticaAges 16 years+ - NCT07239479Recruiting
Dexmedetomidine and desflurane for laparoscopic colon surgery
This study tests a combination of two drugs (dexmedetomidine and desflurane) used during keyhole colon surgery to see if it helps with recovery. It is designed for generally healthy adults having a planned laparoscopic colectomy.
Ho Chi Minh City, Ho Chi MinhAges 18–65 - NCT07237126Recruiting
Single-port robotic surgery for stomach cancer
This trial is testing a newer, less invasive robotic surgery technique that uses just one small incision to remove stomach cancer. It may offer faster recovery and less pain compared to traditional surgery.
Chongqing, Chongqing MunicipalityAges 18–75 - NCT07230795Enrolling by invitation
AI-guided colorectal cancer screening for adults 45-49
This trial tests whether a computer program can help more adults ages 45-49 get screened for colorectal cancer. If you are due for screening and see a Penn Medicine doctor, you may be able to join.
Philadelphia, PennsylvaniaAges 45–49 - NCT07233447Recruiting
H. pylori and stomach cancer in the West Indies
This study looks at how common H. pylori infection is in people with stomach cancer in Guadeloupe. It may help doctors understand the link between this infection and stomach cancer in the region.
Baie-MahaultAges 18 years+ - NCT07230509RecruitingPhase 2
Glue injection to prevent pancreatic leaks after Whipple surgery
This study tests injecting a medical glue into the pancreas during a Whipple procedure to see if it can prevent leaks. It may help people with a soft pancreas and small pancreatic duct.
Minya, Minya GovernorateAges 18–75 - NCT07235904RecruitingPhase 4
Mirikizumab vs standard treatment for newly diagnosed ulcerative colitis
This trial tests if starting with the stronger drug mirikizumab (top-down therapy) works better than the usual treatment with azathioprine for people newly diagnosed with moderate-to-severe ulcerative colitis. It aims to see which approach controls inflammation and improves symptoms faster.
KielAges 18–75 - NCT07232810Recruiting
Surgery With Extra Tissue Removal for Pancreatic Head Cancer
This study tests whether removing extra tissue around the pancreas during a standard surgery improves outlook for people with pancreatic head cancer. You may qualify if you have this type of cancer and are planning surgery without prior chemotherapy or radiation.
Minya, Minya GovernorateAges 18–80 - NCT07239063Recruiting
Lung and colorectal cancer tissue test study
This study checks a new way to prepare large tissue samples from lung or colorectal cancer for faster testing. It may help improve how tumors are analyzed.
Guangzhou, GuangdongAges Any age - NCT06899854Recruiting
Collecting blood and tissue from patients with liver cancer
This study collects blood and tumor tissue samples from people with primary liver cancer who are starting their first treatment (systemic therapy or surgery). The samples help researchers learn more about these cancers and how to improve future treatments.
Pavia, PaviaAges 18–90 - NCT06898398Recruiting
TACE before surgery for large liver cancer
This trial combines a procedure called TACE (which blocks the blood supply to the tumor) with surgery to remove a large liver tumor. It is for people newly diagnosed with a large liver cancer that hasn't spread and can be completely removed with surgery.
Beijing, Beijing MunicipalityAges 18–75 - NCT06908980Recruiting
Predicting survival after gallbladder removal for infected gallbladder
This study is testing a tool to predict survival after gallbladder removal for people with acute cholecystitis caused by gallstones. By joining, you help doctors better assess risk and improve care for future patients.
Pavia, PaviaAges 18 years+ - NCT06908798Recruiting
Using a stool test to predict varices in cirrhosis
This study checks if a simple stool test (fecal calprotectin) can help predict the presence of enlarged veins in the esophagus (varices) in people with cirrhosis. If successful, this could offer a non-invasive way to screen for this serious complication.
Tanta, GharbyeaAges 18 years+ - NCT06908785Recruiting
Blood test to predict bleeding risk after procedures in cirrhosis
This trial is testing if a special blood test called ROTEM can help doctors predict the risk of bleeding after high-risk procedures in people with cirrhosis. It aims to improve safety and guide treatment decisions.
Santander, CantabriaAges 18–65 - NCT04501406RecruitingPhase 2
Low-dose pioglitazone for fatty liver disease in people with type 2 diabetes
This Phase 2 study tests whether low-dose pioglitazone can improve NASH, a type of fatty liver disease, in adults who also have type 2 diabetes. You may be able to join if your diabetes medicines and lab tests meet specific safety and stability requirements.
Gainesville, FloridaAges 21–75
Common questions
- How many digestive system clinical trials are recruiting?
- Clin2 is tracking 7,606 recruiting gastroenterology studies from the U.S. registry right now, out of 12,023 we cover in this area in total.
- What does “Digestive system” cover here?
- Conditions of the stomach, intestines, liver, and the rest of the digestive tract. We group each study into digestive system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a digestive system trial near me?
- Use the search to filter digestive system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.