Gastroenterology
Digestive system clinical trials
Conditions of the stomach, intestines, liver, and the rest of the digestive tract. We’re tracking 7,896 recruiting studies in this area right now.
By phase
- Not applicable4,922
- Phase 21,186
- Phase 1581
- Phase 3466
- Phase 1/Phase 2394
- Phase 4236
- Phase 2/Phase 3111
Top conditions
- Colorectal Cancer492
- Gastric Cancer297
- Pancreatic Cancer292
- Hepatocellular Carcinoma283
- Esophageal Cancer191
- Rectal Cancer176
- Breast Cancer147
- Crohn Disease144
- Ulcerative Colitis141
- Colon Cancer115
- Inflammatory Bowel Diseases108
- Hepatocellular Carcinoma (HCC)106
- Liver Cancer100
- Lung Cancer98
- Pancreas Cancer94
- Esophageal Squamous Cell Carcinoma88
- Ovarian Cancer88
- Cystic Fibrosis78
Leading sponsors
- Fudan University104
- Sun Yat-sen University90
- Mayo Clinic74
- Chinese University of Hong Kong60
- M.D. Anderson Cancer Center58
- Second Affiliated Hospital, School of Medicine, Zhejiang University57
- Assistance Publique - Hôpitaux de Paris55
- Sixth Affiliated Hospital, Sun Yat-sen University50
- National Taiwan University Hospital49
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences48
Where studies are running
- California462
- Arizona177
- Texas149
- Florida134
- Massachusetts128
- New York123
- Alabama122
- Maryland86
- Ohio80
- Pennsylvania72
Recruiting studies7,896 total
- NCT06864195Recruiting
Breath test for liver cancer detection
This study tests a simple breath test to detect liver cancer and monitor liver health. It is looking for patients with liver cancer, liver cirrhosis, primary sclerosing cholangitis, or people with normal livers to see if the breath test can help tell the difference.
LondonAges 18 years+ - NCT06864221Recruiting
How fat molecules in blood affect liver cancer radiotherapy
This study looks at whether certain fats in your blood can help predict how well radiotherapy works for liver cancer. If you are getting radiation for liver cancer, your blood samples may help doctors learn more about your treatment response.
Guangzhou, GuangdongAges 18–80 - NCT06864338Recruiting
Pilot study for a new colorectal cancer screening test
This study tests a new stool-based test for detecting colorectal cancer and advanced polyps. It aims to see how well it works compared to a colonoscopy. The results may lead to a simpler screening option.
Morrisville, North CarolinaAges 18 years+ - NCT06864403RecruitingPhase 4
Mirikizumab for chronic pouch inflammation
This trial tests if mirikizumab can help people with chronic inflammation of the pouch (a surgically created internal reservoir) that doesn't respond well to antibiotics or acts like Crohn's disease. It aims to see if the drug can reduce symptoms like urgency, pain, and bleeding.
Los Angeles, CaliforniaAges 18–80 - NCT06864481Recruiting
Study of liver inflammation from immunotherapy drugs
This study follows people who develop liver inflammation (hepatitis) after starting immunotherapy for cancer. It helps doctors understand how often this happens and how to manage it.
MontpellierAges 18 years+ - NCT06865417RecruitingPhase 3
Filgotinib for children and teens with ulcerative colitis
This trial tests if filgotinib, a pill for adults with ulcerative colitis, works in children and teenagers. It may help those whose current treatments are not working well enough or cause side effects.
Brussels, Brussels CapitalAges 8–18 - NCT06865638Recruiting
Testing for colorectal anastomotic leaks after surgery
This trial is testing a new method to check for leaks after colorectal cancer surgery. The goal is to see if it helps prevent complications and improves recovery.
Nanchong, SichuanAges 18–85 - NCT06866106Recruiting
Well-being in IBS: A phone program for strengths and happiness
This study tests a program that helps people with IBS focus on their strengths and happiness through phone sessions. It aims to see if this approach can improve well-being and manage IBS symptoms.
Boston, MassachusettsAges 18 years+ - NCT06866496Recruiting
Better remission in alcohol-related liver cirrhosis
This trial tests if an optimized treatment plan can improve remission in people with liver cirrhosis caused by alcohol. It aims to help patients achieve better health outcomes.
Hvidovre, Capital RegionAges 18 years+ - NCT06867120Recruiting
Predicting pancreatitis severity with bowel sounds
This study uses a special device to listen to bowel sounds to help predict how severe acute pancreatitis will be. The goal is to find a simple, non-invasive way to guide treatment.
Beijing, Beijing MunicipalityAges 18–85 - NCT06867094RecruitingPhase 2
Study of SAR441566 for Ulcerative Colitis
This trial tests a new medicine called SAR441566 for people with moderate-to-severe ulcerative colitis (UC). It may help reduce symptoms like bleeding and diarrhea if other treatments haven't worked well enough.
Sun City, ArizonaAges 18–75 - NCT06867172Recruiting
Fat in the pancreas in people with cysts or cancer
This study looks at whether fat buildup in the pancreas (called pancreatic steatosis) is common in people who have pancreatic cysts or pancreatic cancer. It may help doctors better understand these conditions.
Bucharest, Sector 1Ages 18 years+ - NCT06867822RecruitingPhase 1
Testing ProAgio for Advanced Colorectal Cancer
This trial tests a new drug called ProAgio for people with advanced or metastatic colorectal cancer. It aims to see if ProAgio can help shrink or slow the cancer when combined with standard treatments.
Birmingham, AlabamaAges 19 years+ - NCT06868992Recruiting
Study of MASH and cell changes in weight-loss surgery
This study looks at a possible link between MASH (liver inflammation with fat buildup) and tiny cell structures that help liver cells work. Researchers want to understand this better in people having weight-loss surgery, where a small liver sample will be taken.
Lyon, FranceAges 18–99 - NCT06868849RecruitingPhase 1/Phase 2
Study of JMT203 for Cancer-Related Weight Loss
This trial tests a new drug called JMT203 for people with cancer-related weight loss (cachexia). It aims to see if the drug can help prevent or reverse weight loss in patients with certain solid tumors who are also receiving or have recently completed anti-cancer therapy.
ZhejiangAges 18 years+ - NCT06868875Recruiting
Small bowel MRI data sharing study
This study asks permission to use past MRI scans of your small bowel for research. It aims to improve how we understand and diagnose bowel conditions.
LondonAges 16 years+ - NCT06869096Recruiting
Flushing liquid during colorectal cancer surgery
This trial compares two different liquids used to flush the surgical area during colorectal cancer surgery to see which one better prevents infections. If you are having surgery for colorectal cancer, you may be able to join.
Nanchong, SichuanAges 18–85 - NCT06869213RecruitingPhase 2
Adebrelimab plus chemo before and after surgery for esophageal cancer
This trial tests a combination of the immunotherapy drug adebrelimab (SHR-1316) and chemotherapy given before and after surgery for locally advanced esophageal squamous cell carcinoma that can be removed. The goal is to see if this approach helps shrink the tumor and improves outcomes.
BeijingAges 18–75 - NCT06869226RecruitingPhase 2
Study of camrelizumab plus chemo before surgery for esophageal cancer
This trial tests whether giving the immunotherapy drug camrelizumab together with chemotherapy before surgery can help people with esophageal cancer avoid needing full removal of the esophagus. It aims to preserve the esophagus while still treating the cancer effectively.
BeijingAges 18–75 - NCT06869694Recruiting
Energy ct scan for stomach cancer diagnosis
This study uses a special type of ct scan (energy ct) to help doctors see stomach cancer more clearly. If you have been diagnosed with stomach cancer and are scheduled for surgery, this imaging test may help guide your treatment.
Zhengzhou, ChinaAges 18 years+ - NCT06870019Recruiting
Hepatitis C tracker study for unsheltered homelessness
This study tests a simple treatment for Hepatitis C in people experiencing unsheltered homelessness. It aims to help those who are receiving street medicine care and have not been treated before.
Alhambra, CaliforniaAges 18 years+ - NCT06870630Recruiting
Comparing two myotomy methods for type 2 achalasia
This trial tests two muscle-cutting procedures for people newly diagnosed with type 2 achalasia (a swallowing disorder). The goal is to see if a more complex myotomy works better than the standard one.
Hyderabad, TelanganaAges 18–75 - NCT06870942RecruitingPhase 2
Radiation therapy for liver cancer that progresses after first immunotherapy
This trial tests whether adding targeted radiation to liver cancer patients who have limited progression after initial immunotherapy can help control the disease. It is for people with hepatocellular carcinoma (HCC) whose cancer has started to grow in just a few spots after their first PD-1 treatment.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT06871111RecruitingPhase 1
Bacteria treatment study for liver disease patients
This trial tests whether giving a mixture of helpful bacteria can improve gut health in people hospitalized with serious liver problems. It aims to see if restoring these bacteria can help with recovery.
Chicago, IllinoisAges 18 years+
Common questions
- How many digestive system clinical trials are recruiting?
- Clin2 is tracking 7,896 recruiting gastroenterology studies from the U.S. registry right now, out of 12,425 we cover in this area in total.
- What does “Digestive system” cover here?
- Conditions of the stomach, intestines, liver, and the rest of the digestive tract. We group each study into digestive system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a digestive system trial near me?
- Use the search to filter digestive system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.