Gastroenterology
Digestive system clinical trials
Conditions of the stomach, intestines, liver, and the rest of the digestive tract. We’re tracking 7,896 recruiting studies in this area right now.
By phase
- Not applicable4,922
- Phase 21,186
- Phase 1581
- Phase 3466
- Phase 1/Phase 2394
- Phase 4236
- Phase 2/Phase 3111
Top conditions
- Colorectal Cancer492
- Gastric Cancer297
- Pancreatic Cancer292
- Hepatocellular Carcinoma283
- Esophageal Cancer191
- Rectal Cancer176
- Breast Cancer147
- Crohn Disease144
- Ulcerative Colitis141
- Colon Cancer115
- Inflammatory Bowel Diseases108
- Hepatocellular Carcinoma (HCC)106
- Liver Cancer100
- Lung Cancer98
- Pancreas Cancer94
- Esophageal Squamous Cell Carcinoma88
- Ovarian Cancer88
- Cystic Fibrosis78
Leading sponsors
- Fudan University104
- Sun Yat-sen University90
- Mayo Clinic74
- Chinese University of Hong Kong60
- M.D. Anderson Cancer Center58
- Second Affiliated Hospital, School of Medicine, Zhejiang University57
- Assistance Publique - Hôpitaux de Paris55
- Sixth Affiliated Hospital, Sun Yat-sen University50
- National Taiwan University Hospital49
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences48
Where studies are running
- California462
- Arizona177
- Texas149
- Florida134
- Massachusetts128
- New York123
- Alabama122
- Maryland86
- Ohio80
- Pennsylvania72
Recruiting studies7,896 total
- NCT06871267Recruiting
Dietary changes for mild to moderate Crohn's disease
This study looks at how changing your diet might help people with Crohn's disease feel better. It is for adults with mild to moderate Crohn's who are not using a liquid-only diet and have not had recent surgery.
Kuala Lumpur, Petaling JayaAges 18–50 - NCT06872515Recruiting
Exercise before esophageal cancer surgery
This trial tests if doing supervised exercise before esophageal cancer surgery (called prehabilitation) helps people recover better. You would follow a personalized exercise plan for at least 2 weeks before your scheduled surgery.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT06873269Recruiting
Holmium-166 radiation therapy for liver cancer
This trial tests a radiation treatment for liver cancer that cannot be removed with surgery or ablation. Tiny beads containing Holmium-166 are injected into the liver's blood supply to target the tumor directly.
BrusselsAges 18 years+ - NCT06873659RecruitingPhase 1
Testing SON-DP for advanced solid tumors
This trial tests a new drug called SON-DP for people with advanced solid tumors that haven't responded to standard treatments. It aims to see if the drug is safe and helps shrink or control the cancer.
Beijing, Beijing MunicipalityAges 18–75 - NCT06873763RecruitingPhase 1/Phase 2
Nelmastobart with chemo for advanced colorectal cancer
This trial tests a new immunotherapy drug, nelmastobart, combined with two standard chemotherapy drugs (trifluridine/tipiracil and bevacizumab) for people with advanced colorectal cancer that hasn't responded to other treatments. The goal is to see if this combination can shrink tumors or slow the cancer's growth.
Seongnam-si, Gyeonggi-doAges 19 years+ - NCT06874036Recruiting
Bowel prep and colonoscopy safety in heart, kidney, or liver disease
This study tests how well people with chronic heart, kidney, or liver disease tolerate bowel preparation and colonoscopy. It aims to ensure the procedure is safe and effective for you.
Hyderabad, TelanganaAges 18–75 - NCT06874127Recruiting
Predicting liver repair in hepatitis B after treatment
This study looks at whether non-invasive tests can tell if liver damage is reversing in people with hepatitis B who have been on antiviral therapy for at least a year. It aims to help avoid repeated liver biopsies.
BeijingAges 18 years+ - NCT06874296Recruiting
Testing machine perfusion for declined livers to shorten transplant wait time
This trial tests whether using a machine to keep donated livers healthy (normothermic machine perfusion) can allow more people to receive a transplant sooner. It is for patients who are already on the waiting list for a liver and have a moderately severe MELD score (25 or less).
Hamburg, Free and Hanseatic City of HamburgAges 18 years+ - NCT06876753Recruiting
Advanced liver cancer: TACE with immunotherapy and anti-angiogenesis
This trial is for people with advanced liver cancer (HCC) that has spread outside the liver. It tests whether combining a TACE procedure with immunotherapy and anti-angiogenesis drugs can improve outcomes. You must not have had prior systemic therapy and must have received TACE in a specific time window around starting these drugs.
Nanjing, JiangsuAges 18–80 - NCT06877637Recruiting
Tracking bile duct and liver cancer during treatment
This study tracks how bile duct and liver cancers change during treatment, to help doctors find the best therapies for patients. It is for people who are newly diagnosed or starting a new treatment.
KristianstadAges 18 years+ - NCT06877923Recruiting
Elemental 028 extra nutritional support study
This study is testing a special liquid food called Elemental 028 Extra for people who need at least 30% of their nutrition from an elemental formula. It aims to see how well it works and how people tolerate it.
TrowbridgeAges 3 years+ - NCT06878131Recruiting
Precision-MRD: Targeted therapy study for colorectal cancer with MRD
This study looks at how well targeted therapies work for people with colorectal cancer who have minimal residual disease (MRD, tiny amounts of cancer left after treatment) detected by a blood test. It is for people who have a specific genetic change (biomarker) in their tumor and have not been treated with the targeted therapy for that biomarker before.
Houston, TexasAges 18 years+ - NCT06878209Recruiting
Cough and hemorrhoids study
This study looks at how coughing may relate to hemorrhoids. Researchers want to understand the possible connection in people who have hemorrhoids but haven't had surgery for them.
Muğla, MenteşeAges 18 years+ - NCT06881043Recruiting
Robotic surgery tool for advanced stomach cancer
This trial tests a robotic surgical tool that seals blood vessels in advanced stomach cancer. It aims to see if the tool works safely and effectively during robot-assisted surgery.
Changchun, JilinAges 18–75 - NCT06881004Recruiting
Biliary Dilation National Cohort Study in China
This study collects health information from people in China who have biliary dilation (widening of the bile ducts). It looks at their medical history and follows some patients over time to learn more about the condition.
Beijing, Beijing MunicipalityAges Up to 80 years - NCT06881082Recruiting
Comparing two banding methods for esophageal varices
This trial compares two different ways of using rubber bands to treat swollen veins in the food pipe (varices) caused by cirrhosis. It aims to find which method is better at preventing first-time bleeding.
Tanta, GharbyeaAges 18 years+ - NCT06881238Recruiting
How hepatitis B affects inflammatory bowel disease
This study looks at how hepatitis B virus affects people with inflammatory bowel disease (IBD). It may help doctors better understand the link between the two conditions.
Tanta, GharbyeaAges 18 years+ - NCT06881511Recruiting
Betaine for autoimmune gastritis
This study tests whether betaine hydrochloride, a supplement that helps with digestion, can improve symptoms in people with autoimmune gastritis. It is for adults who have been diagnosed with this condition and have high gastrin levels or a related stomach history.
Hangzhou, ZhejiangAges 18–80 - NCT06881628RecruitingPhase 4
Tranexamic acid and vitamin K for bleeding in cirrhosis
This trial tests if giving tranexamic acid and vitamin K by injection can help control bleeding from the upper digestive tract in people with liver cirrhosis. It may offer a way to stop bleeding more quickly.
Tanta, GharbyeaAges 18 years+ - NCT06881992RecruitingPhase 3
Testing ersodetug for low blood sugar from neuroendocrine tumors
This study tests a new medicine called ersodetug in people whose neuroendocrine tumors cause dangerously low blood sugar that standard treatments can't control. If you need IV sugar or nutrition for at least a week, this trial may offer a new option to help manage your blood sugar.
Chicago, IllinoisAges 18 years+ - NCT06882993Recruiting
Testing a gentler approach to diagnose Crohn's disease
This trial tests a new, gentler way to diagnose Crohn's disease. If you have symptoms like long-lasting diarrhea or belly pain, this study may help find out if you have Crohn's without invasive procedures.
EsbjergAges 18–40 - NCT06883175Recruiting
New ways to measure how your esophagus works
This study uses special probes to measure the movement and pressure in your esophagus (the tube connecting your mouth to your stomach) to better understand swallowing problems like achalasia, GERD, and other conditions. The goal is to improve how doctors diagnose and treat these issues.
Chicago, IllinoisAges 18–85 - NCT06883539RecruitingPhase 1
Study of LXP1788 for advanced solid tumors
This trial tests a new drug called LXP1788 in people with advanced solid tumors that have not responded to other treatments. The goal is to see if it is safe and how it affects the body.
TaichungAges 18 years+ - NCT06885710RecruitingPhase 1
T cell therapy with antivirals for chronic hepatitis B
This study tests a new treatment that uses your own immune cells (T cells) modified to attack the hepatitis B virus, combined with standard antiviral medication. It is for people with chronic hepatitis B who have a specific HLA type and no advanced liver scarring.
ShanghaiAges 18–65
Common questions
- How many digestive system clinical trials are recruiting?
- Clin2 is tracking 7,896 recruiting gastroenterology studies from the U.S. registry right now, out of 12,425 we cover in this area in total.
- What does “Digestive system” cover here?
- Conditions of the stomach, intestines, liver, and the rest of the digestive tract. We group each study into digestive system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a digestive system trial near me?
- Use the search to filter digestive system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.