Gastroenterology
Digestive system clinical trials
Conditions of the stomach, intestines, liver, and the rest of the digestive tract. We’re tracking 7,903 recruiting studies in this area right now.
By phase
- Not applicable4,926
- Phase 21,187
- Phase 1582
- Phase 3466
- Phase 1/Phase 2395
- Phase 4236
- Phase 2/Phase 3111
Top conditions
- Colorectal Cancer493
- Gastric Cancer297
- Pancreatic Cancer292
- Hepatocellular Carcinoma284
- Esophageal Cancer191
- Rectal Cancer176
- Breast Cancer147
- Crohn Disease144
- Ulcerative Colitis141
- Colon Cancer115
- Inflammatory Bowel Diseases108
- Hepatocellular Carcinoma (HCC)106
- Liver Cancer101
- Lung Cancer98
- Pancreas Cancer94
- Esophageal Squamous Cell Carcinoma88
- Ovarian Cancer88
- Cystic Fibrosis78
Leading sponsors
- Fudan University104
- Sun Yat-sen University91
- Mayo Clinic74
- Chinese University of Hong Kong60
- M.D. Anderson Cancer Center58
- Second Affiliated Hospital, School of Medicine, Zhejiang University57
- Assistance Publique - Hôpitaux de Paris55
- Sixth Affiliated Hospital, Sun Yat-sen University50
- National Taiwan University Hospital49
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences48
Where studies are running
- California462
- Arizona177
- Texas149
- Florida135
- Massachusetts127
- New York123
- Alabama122
- Maryland86
- Ohio80
- Pennsylvania72
Recruiting studies7,903 total
- NCT07087561Recruiting
Nutrition and health education after colorectal cancer surgery
This trial tests whether a short-term nutritional supplement combined with health education can improve recovery after surgery for colorectal cancer. It is for people with stage IIa, IIb, or IIIa colon or rectal cancer who have completed surgery and are able to engage in follow-up.
Xi'an, ShaanxiAges 18 years+ - NCT07088354Recruiting
AI model predicts treatment response in esophageal cancer
This trial tests whether an artificial intelligence (AI) model can accurately predict if esophageal cancer will completely disappear after chemotherapy combined with immunotherapy before surgery. If successful, it could help doctors decide the best treatment plan for patients.
Wuhan, HubeiAges 18 years+ - NCT07089030Recruiting
Capsule endoscopy for unexplained anemia on blood thinners
This study uses a capsule endoscopy (a pill-sized camera you swallow) to look for hidden sources of bleeding in the small intestine of people who have iron deficiency anemia and take blood thinners. Finding the cause may help manage your anemia and avoid unnecessary repeat tests.
Trois-Rivières, QuebecAges 18–90 - NCT07089277Recruiting
Validating a bleeding risk score for stomach bleeding
This study checks how well a risk score predicts the need for treatment in patients with upper gastrointestinal bleeding (bleeding in the stomach or esophagus). It may help doctors decide if you need urgent care.
SousseAges 18 years+ - NCT07089940RecruitingEarly Phase 1
OMO-103 for advanced pancreatic cancer
This trial tests a new drug called OMO-103 in people with advanced pancreatic cancer that has spread or cannot be removed by surgery. It may be an option whether you have had treatment before or not, as long as it's been at least 2 weeks since your last therapy.
Portland, OregonAges 18 years+ - NCT07090291Recruiting
China colorectal cancer screening trial for adults 45–74
This trial is testing a new way to screen for colorectal cancer in adults aged 45 to 74. If you join, you will help researchers find better methods for early detection.
GuandongAges 45–74 - NCT07090759RecruitingPhase 3
Test of new drug for hepatitis B not fully controlled by current treatment
This trial tests a new drug called GST-HG141 for people with chronic hepatitis B whose virus is still active despite taking standard antiviral pills. It aims to see if the new drug can better control the virus.
Hangzhou, ZhejiangAges 18–70 - NCT07091032Recruiting
Building connections for better health
This study tests if helping people address obesity, cancer screenings, or mental health struggles can improve their overall health. You may qualify if you have obesity, are behind on colon or cervical cancer screening, or have depression or anxiety.
Boston, MassachusettsAges 18–75 - NCT07091526Recruiting
Does controlling uric acid help after pancreatic cancer surgery?
This study is checking if controlling uric acid (a normal body waste product) can help people with pancreatic cancer live longer after surgery. If you have had successful surgery and are otherwise healthy, this trial might be for you.
Lanzhou, GansuAges 18–85 - NCT07091942Recruiting
Curative therapy after Atezo-Bev for advanced liver cancer
This trial is for people with liver cancer who have already been treated with Atezo-Bev (a combination of atezolizumab and bevacizumab) and whose tumors have shrunk significantly. The goal is to see if further curative treatments can be used to improve outcomes.
Taipei, SelectAges Any age - NCT07093294Recruiting
Predicting vedolizumab success with ultrasound in early Crohn's
This study uses intestinal ultrasound to see if vedolizumab can heal the gut in people recently diagnosed with Crohn's disease. It aims to find early signs that the treatment is working.
Changsha, HunanAges 18–80 - NCT07093346Recruiting
Pectin supplement for fatty liver disease
This study tests whether a pectin supplement (a fiber found in fruits) can reduce inflammation and improve liver and metabolic health in people with fatty liver disease (MASLD). You might be eligible if you have MASLD, a healthy weight range, and can avoid certain medications and foods.
NottinghamAges 18 years+ - NCT07093359RecruitingPhase 3
LINX vs fundoplication for acid reflux surgery
This trial compares two surgical treatments for acid reflux (GERD) that isn't well controlled with medication. It tests if the LINX device (a magnetic ring around the esophagus) works as well or better than fundoplication (a stomach wrap). It may help people who need surgery for reflux.
Oxford, OxfordshireAges 18 years+ - NCT07094204RecruitingPhase 1
A study of ASP5834 for adults with solid tumors and KRAS mutations
This trial is testing a new drug called ASP5834 for people with advanced solid tumors that have a specific change in the KRAS gene. The study will find the best dose and see if it helps shrink tumors.
Santa Monica, CaliforniaAges 18 years+ - NCT07095439RecruitingPhase 2
Sandwich treatment for stage 2 and 3 rectal cancer
This trial tests a new way of giving radiation and chemotherapy before surgery for rectal cancer that hasn't spread. It aims to see if this 'sandwich' approach is safe and works better than standard treatment.
CairoAges 18–70 - NCT07095517RecruitingPhase 1
Preventing early-onset colorectal tumors with tirzepatide
This study tests if tirzepatide can help prevent early-onset colorectal tumors in people aged 18-50 who have had certain types of polyps removed. It aims to find risk factors and ways to stop colorectal cancer before it starts.
Boston, MassachusettsAges 18–50 - NCT07098026Recruiting
Herbal mixture plus chemo before surgery for advanced stomach cancer
This trial tests whether adding an herbal mixture (Shenqi Fuwei Mixture) to standard chemotherapy before surgery can help treat locally advanced stomach cancer. It is for people whose cancer has not spread to distant sites and who are healthy enough to undergo treatment and surgery.
Changsha, HunanAges 18–75 - NCT07098182Recruiting
Preserving blood supply during colon or rectal surgery
This trial tests a technique during colon or rectal surgery to preserve a specific blood vessel (the left colic artery) that helps keep the remaining colon healthy. It is for people with left colon, rectal, or ovarian cancer who are scheduled for surgery.
Montpellier, HeraultAges 18 years+ - NCT07098598RecruitingPhase 2/Phase 3
Using FAPI-PET to diagnose pancreatic cancer
This trial uses a special imaging scan called FAPI-PET to help doctors better diagnose pancreatic cancer. If you are suspected of having pancreatic cancer or a recurrence, this study may help confirm or clarify your diagnosis.
TurkuAges 18–85 - NCT07098767Recruiting
Swallowing Ultrasound Study for People with Swallowing Difficulty
This trial tests whether an ultrasound can reliably evaluate swallowing problems. It aims to find a non-invasive way to assess your swallowing, which could help guide your care.
TaipeiAges 18 years+ - NCT07099118RecruitingPhase 1
Safety and tolerability of HEC169584 in healthy people
This early-stage study checks if a new medicine called HEC169584 is safe for people and how it moves through the body. It looks for healthy volunteers to take part.
Beijing, Beijing MunicipalityAges 18–45 - NCT07099417Recruiting
Screening for heart valve disease with a single-lead ECG
This study tests whether a simple single-lead heart monitor (ECG) can spot problems with your heart valves. It may be a quick, easy way to screen for valve disease.
MoscowAges 18 years+ - NCT07100379Recruiting
Balloon time study for esophageal narrowing after surgery
This study compares two balloon inflation times (30 seconds vs 60 seconds) to see which works better for treating narrow spots in the esophagus that form after esophageal atresia repair.
Boston, MassachusettsAges Up to 18 years - NCT07100392RecruitingPhase 2
A new drug combo for advanced liver cancer after first treatment fails
This study tests a combination of three drugs—TUDCA (a bile acid supplement), camrelizumab (an immunotherapy), and regorafenib (a targeted therapy)—for people with advanced liver cancer that has continued to grow after earlier immunotherapy plus Avastin treatment. The goal is to see if this new mix can help stop the cancer from growing.
Shanghai, Shanghai MunicipalityAges 18 years+
Common questions
- How many digestive system clinical trials are recruiting?
- Clin2 is tracking 7,903 recruiting gastroenterology studies from the U.S. registry right now, out of 12,451 we cover in this area in total.
- What does “Digestive system” cover here?
- Conditions of the stomach, intestines, liver, and the rest of the digestive tract. We group each study into digestive system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a digestive system trial near me?
- Use the search to filter digestive system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.