Gastroenterology
Digestive system clinical trials
Conditions of the stomach, intestines, liver, and the rest of the digestive tract. We’re tracking 7,903 recruiting studies in this area right now.
By phase
- Not applicable4,926
- Phase 21,187
- Phase 1582
- Phase 3466
- Phase 1/Phase 2395
- Phase 4236
- Phase 2/Phase 3111
Top conditions
- Colorectal Cancer493
- Gastric Cancer297
- Pancreatic Cancer292
- Hepatocellular Carcinoma284
- Esophageal Cancer191
- Rectal Cancer176
- Breast Cancer147
- Crohn Disease144
- Ulcerative Colitis141
- Colon Cancer115
- Inflammatory Bowel Diseases108
- Hepatocellular Carcinoma (HCC)106
- Liver Cancer101
- Lung Cancer98
- Pancreas Cancer94
- Esophageal Squamous Cell Carcinoma88
- Ovarian Cancer88
- Cystic Fibrosis78
Leading sponsors
- Fudan University104
- Sun Yat-sen University91
- Mayo Clinic74
- Chinese University of Hong Kong60
- M.D. Anderson Cancer Center58
- Second Affiliated Hospital, School of Medicine, Zhejiang University57
- Assistance Publique - Hôpitaux de Paris55
- Sixth Affiliated Hospital, Sun Yat-sen University50
- National Taiwan University Hospital49
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences48
Where studies are running
- California462
- Arizona177
- Texas149
- Florida135
- Massachusetts127
- New York123
- Alabama122
- Maryland86
- Ohio80
- Pennsylvania72
Recruiting studies7,903 total
- NCT07295236Recruiting
Vacuum therapy for a leak after stomach surgery
This trial tests whether a treatment called endoscopic vacuum therapy can help heal a small leak that can happen after stomach removal surgery. If you are stable and the leak is small, this treatment may help you avoid more surgery.
KyivAges 18–90 - NCT07295262RecruitingEarly Phase 1
New imaging to guide liver cancer surgery
This trial tests a new imaging technique that uses a special dye combined with a chemotherapy drug to help surgeons see and remove liver cancer more precisely during surgery. It is for people with a first-time, single liver tumor that is small and can be surgically removed.
Chengdu, SichuanAges 18–75 - NCT07295340Recruiting
New imaging dye test for liver cancer detection
This trial tests a special dye that targets liver cancer cells to help surgeons see tumor edges more clearly during surgery. It may help ensure all cancer is removed in one operation.
Chengdu, SichuanAges 18–80 - NCT07295886Recruiting
Cream for Protruding Hemorrhoids
This trial tests a cream containing two medicines (nifedipine and lidocaine) for painful, protruding hemorrhoids. The cream may help reduce pain and swelling. You can join if you have moderate to severe hemorrhoids that come out of the anus and have already started the cream in the last five days.
NaplesAges 18–75 - NCT07295990Recruiting
Tongue exercises for people with ALS
This trial tests whether simple tongue-strengthening exercises can help people with ALS who have mild swallowing trouble. If you have ALS and notice your tongue getting weaker, this study may help you keep your swallowing strength.
Davie, FloridaAges 18–99 - NCT07296237Recruiting
Women's sexual health after anal cancer radiation
This study looks at how women feel about their gynecological and sexual health after finishing radiation therapy for anal cancer. It may help doctors learn how to better support their patients after treatment.
AarhusAges 18 years+ - NCT07296458RecruitingPhase 3
Fenofibrate for first-line treatment of primary biliary cholangitis
This study tests whether fenofibrate, a medicine that lowers fats in the blood, can help people with primary biliary cholangitis (a chronic liver disease) who haven't had treatment before. It aims to see if it is safe and effective as a first treatment option.
Xi'an, ShaanxiAges 18–75 - NCT07298343RecruitingPhase 2
Testing ZED1227 for non-responsive celiac disease
This trial tests a new medicine, ZED1227, for people with celiac disease who still have symptoms despite eating gluten-free. The goal is to see if it helps reduce those symptoms.
MainzAges 18–80 - NCT07299071Recruiting
Can AI make screening colonoscopy better at finding precancerous polyps?
This study tests whether artificial intelligence (CAD) can help doctors find more polyps during screening colonoscopy, with the goal of lowering the risk of advanced adenomas (precancerous growths) over 3 years.
BayonneAges 18 years+ - NCT07299448Recruiting
Parkinson's and swallowing: what drives difficulty?
This study looks at why some people with Parkinson's have trouble swallowing (dysphagia) and how the brain adapts. It aims to understand the condition better, which could lead to better treatments.
Düsseldorf, North Rhine-WestphaliaAges 18 years+ - NCT07300553RecruitingPhase 2
Gut bacteria and energy metabolism in health and IBD
This study looks at how the bacteria living in your gut affect your body's energy use. It includes both healthy volunteers and people with inactive Crohn's disease or ulcerative colitis.
ParisAges 18–50 - NCT07301216Recruiting
Copper in urine after stopping Wilson disease therapy
This study is looking at what happens to copper levels in the urine when people with Wilson disease briefly stop their medicine. It may help doctors understand how well your body controls copper without treatment.
New Haven, ConnecticutAges 18 years+ - NCT07301814Recruiting
PET imaging for CLDN18.2 in cancer patients
This study uses a special PET scan to look for a protein called CLDN18.2 on cancer cells. It may help doctors better understand certain cancers like stomach, pancreas, bile duct, or esophageal cancer and guide treatment decisions.
Wuhan, HubeiAges 18 years+ - NCT07301892Recruiting
AI help for rheumatoid arthritis diagnosis
This trial tests whether artificial intelligence (AI) can improve how doctors spot complications in people newly diagnosed with rheumatoid arthritis (RA), a condition that causes joint pain and swelling. The goal is to see if AI can make diagnosis faster and more accurate in real-world hospital settings.
Beijing, Beijing MunicipalityAges Any age - NCT07303140Recruiting
Liver stiffness in young people with glycogen storage disease type III
This study looks at liver stiffness (a sign of scarring, called fibrosis) in children and young adults with type III glycogen storage disease. Researchers want to see how common liver fibrosis is in this group and how it changes over time, using a non-invasive ultrasound-like test called elastography.
StrasbourgAges 1 month–21 years - NCT07303621Recruiting
Study of Trikafta in children with cystic fibrosis
This study looks at how the drug Trikafta (also called Kaftrio) works in children aged 2 to 17 with cystic fibrosis. The goal is to learn how the body processes the medicine so doctors can find the best dose.
BronAges 2–17 - NCT07303686RecruitingPhase 4
Reducing Stelara dose in Crohn's and colitis remission
This trial studies whether people with Crohn's disease or ulcerative colitis who are in deep remission can safely reduce their dose of ustekinumab (Stelara) without the disease coming back. It aims to reduce medication burden while keeping patients well.
Montreal, QuebecAges 18 years+ - NCT07303712Recruiting
Liquid Biopsy for Liver Cancer After Y90 Treatment
This study uses a simple blood test (called a liquid biopsy) to learn more about your liver cancer after you receive a targeted radiation treatment called Y90 radioembolization. The goal is to see if the blood test can help doctors better understand how the cancer responds to treatment.
Palo Alto, CaliforniaAges 18 years+ - NCT07303725Recruiting
Spectral CT scan during cancer tumor treatment
This study tests a special CT scan used during procedures to treat tumors, like blocking blood flow or burning the tumor. It may help doctors see tumors more clearly during the treatment.
Palo Alto, CaliforniaAges 18 years+ - NCT07304466Recruiting
Terlipressin and somatostatin for portal pressure in liver transplant
This study tests two medicines (terlipressin and somatostatin) to see how they affect pressure in the portal vein during liver transplant. It may help people with high portal pressure who are getting a right lobe living donor liver transplant.
Istanbul, BagcilarAges 18–70 - NCT07305428Recruiting
Making large liver tumors removable with immunotherapy and focused radiation
This trial tests a combination of immunotherapy and high-precision radiation (SBRT) to shrink large or multiple liver tumors in people with hepatocellular carcinoma, with the goal of making them small enough for surgery. It's for people who cannot currently have their tumors removed but might become eligible after treatment.
Hong KongAges 18–80 - NCT07305454Recruiting
Teaching exercise habits for Crohn's and colitis
This study tests whether structured education sessions about exercise can help people with Crohn's or colitis be more active. It looks at how this education affects your physical activity levels and overall health.
ToulouseAges 18–100 - NCT07307560Recruiting
High-flow oxygen during sedation for sleep apnea patients having endoscopy
This study tests if high-flow nasal oxygen can prevent oxygen drops during sedated endoscopy in patients with severe obstructive sleep apnea. It may help people who are at higher risk of breathing problems during the procedure.
Hangzhou, ZhejiangAges 18 years+ - NCT07307586RecruitingPhase 3
Azvudine for new hepatitis B patients
This study tests a new pill (azvudine) to see if it can cure chronic hepatitis B in people who have never been treated before. It is for those with active infection and elevated liver enzymes.
Zhengzhou, HenanAges 18–65
Common questions
- How many digestive system clinical trials are recruiting?
- Clin2 is tracking 7,903 recruiting gastroenterology studies from the U.S. registry right now, out of 12,451 we cover in this area in total.
- What does “Digestive system” cover here?
- Conditions of the stomach, intestines, liver, and the rest of the digestive tract. We group each study into digestive system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a digestive system trial near me?
- Use the search to filter digestive system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.