Gastroenterology
Digestive system clinical trials
Conditions of the stomach, intestines, liver, and the rest of the digestive tract. We’re tracking 7,916 recruiting studies in this area right now.
By phase
- Not applicable4,936
- Phase 21,188
- Phase 1583
- Phase 3465
- Phase 1/Phase 2396
- Phase 4237
- Phase 2/Phase 3111
Top conditions
- Colorectal Cancer493
- Gastric Cancer298
- Pancreatic Cancer292
- Hepatocellular Carcinoma284
- Esophageal Cancer191
- Rectal Cancer176
- Breast Cancer148
- Crohn Disease144
- Ulcerative Colitis140
- Colon Cancer115
- Inflammatory Bowel Diseases108
- Hepatocellular Carcinoma (HCC)107
- Liver Cancer101
- Lung Cancer99
- Pancreas Cancer94
- Esophageal Squamous Cell Carcinoma89
- Ovarian Cancer88
- Cystic Fibrosis78
Leading sponsors
- Fudan University104
- Sun Yat-sen University91
- Mayo Clinic75
- Chinese University of Hong Kong60
- M.D. Anderson Cancer Center58
- Second Affiliated Hospital, School of Medicine, Zhejiang University57
- Assistance Publique - Hôpitaux de Paris55
- Sixth Affiliated Hospital, Sun Yat-sen University50
- National Taiwan University Hospital49
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences48
Where studies are running
- California461
- Arizona174
- Texas148
- Florida135
- Massachusetts127
- Alabama123
- New York123
- Maryland87
- Ohio80
- Pennsylvania72
Recruiting studies7,916 total
- NCT07107815Enrolling by invitation
Predicting rectal cancer treatment response using MRI
This study uses advanced MRI scanning and computer analysis to predict how well rectal cancer might respond to treatments given before surgery. It may help doctors choose the best approach for you.
Beijing, Beijing MunicipalityAges Any age - NCT07103772Enrolling by invitation
Does a food supplement help irritable bowel syndrome?
This study tests a special food-based supplement (called a nutraceutical) to see if it helps relieve symptoms of irritable bowel syndrome (IBS), like diarrhea and constipation. It is only open to UANL employees and their beneficiaries who are not already on medication for their stomach issues.
Monterrey, Nuevo LeónAges 18 years+ - NCT07098715Enrolling by invitation
Kerecis SurgiClose for draining fistula wounds
This trial tests a special dressing made from fish skin (Kerecis SurgiClose) to help heal fistula-in-ano wounds that won't close on their own. It may help people with this type of anal fistula heal faster.
Rochester, MinnesotaAges 18 years+ - NCT07097753Enrolling by invitation
Comparing two surgeries for infected pancreatic necrosis
This trial compares a newer, minimally invasive surgery (MIPPED-C) with standard open surgery (OSN) for treating infected pancreatic necrosis. It aims to see which approach leads to better recovery and outcomes.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07095634Enrolling by invitation
Heart risk study for Crohn's and colitis patients
This study looks at heart health in people with Crohn's disease or ulcerative colitis. It aims to understand the risk of heart problems over 2 years.
San Donato Milanese, MilanAges 16 years+ - NCT07088081Enrolling by invitation
Immunotherapy drugs for advanced liver cancer
This trial tests two types of immunotherapy (atezolizumab with bevacizumab or durvalumab with tremelimumab) for people with advanced liver cancer that hasn't been treated with systemic therapy before. It aims to see if these treatments are safe and effective.
Cairo, AbbasyaAges 18 years+ - NCT07080996Enrolling by invitationPhase 3
Biofeedback tongue strengthening for better swallowing
This trial tests whether a biofeedback tongue strengthening program can improve tongue pressure and swallowing ability in older adults. It may help if you have weak tongue muscles but no other conditions affecting your tongue.
Salaya, Changwat Nakhon PathomAges 60 years+ - NCT07057258Enrolling by invitation
Injection vs. surgery for laryngeal clefts in children
This trial compares two treatments for children who have a gap in their voice box (laryngeal cleft) that causes liquid to go into their lungs. One treatment is an injection to close the gap, and the other is surgery with stitches.
Portland, OregonAges 1–10 - NCT07052448Enrolling by invitation
Radiation after triple therapy for liver cancer
This trial tests whether adding radiation therapy after a combination of three treatments (like immunotherapy and targeted therapy) can help people with liver cancer that cannot be surgically removed. It may be a good option if your tumor responded to the triple therapy but you still cannot have surgery.
Fuzhou, FujianAges 18–75 - NCT07050485Enrolling by invitation
Postbiotic gummies after GI cancer surgery
This trial tests if taking postbiotic gummies (a type of supplement that helps good gut bacteria) can help your gut recover faster after surgery for stomach, colon, or other gastrointestinal cancers. It is for people having scheduled, minimally invasive (laparoscopic) surgery to remove their cancer.
Tampa, FloridaAges 18 years+ - NCT07047937Enrolling by invitation
Machine learning to predict early gastric cancer
This study uses machine learning to find patterns in patient data that might help predict early-stage stomach cancer. It could help doctors catch the disease sooner.
Wenzhou, ZhejiangAges Any age - NCT07046832Enrolling by invitation
Augmented reality needle guidance for soft tissue biopsy
This trial tests a new augmented reality system that helps guide the needle during a soft-tissue biopsy. It may make the procedure more accurate and easier for your doctor.
Washington D.C., District of ColumbiaAges 18 years+ - NCT07042841Enrolling by invitation
AI planning system for liver cancer treatment
This trial uses an AI system to help doctors plan surgery for liver cancer. It is for people who have had a CT scan of their liver and may or may not have a liver tumor.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07035132Enrolling by invitation
Special supplement for patients with cancer at risk of malnutrition
This trial tests a special liquid supplement for patients with head, neck, lung, rectal, or esophageal cancer who are having radiation and are malnourished or at risk. The supplement is designed to be easier to digest if you have stomach or gut issues.
AlicanteAges 18 years+ - NCT07023861Enrolling by invitationEarly Phase 1
New imaging test for HER2-positive cancers
This trial tests a new imaging method that uses a radioactive tracer to find HER2-positive cancer cells in the body. It may help doctors see tumors more clearly in people with stomach, breast, or bladder cancer.
Wuxi, JiangsuAges 15–75 - NCT07023848Enrolling by invitationEarly Phase 1
Imaging study for HER2-positive cancers using a special tracer
This study uses a radioactive tracer to take pictures of tumors that have a protein called HER2. It may help doctors see where the cancer is in your body and could guide future treatment decisions.
Wuxi, JiangsuAges 18–75 - NCT07016737Enrolling by invitationPhase 3
Chemotherapy and radiation for returning esophageal cancer
This trial tests if adding radiation before and after standard chemotherapy can help people whose esophageal cancer has come back after initial treatment. It aims to improve control of the cancer while keeping side effects manageable.
Nanjing, JiangsuAges 18 years+ - NCT06997458Enrolling by invitation
Liquid biopsy study for advanced lung or colon cancer
This study is testing a simple blood draw (liquid biopsy) to track advanced lung or colon cancer. It may help doctors understand the cancer better without needing repeated tissue biopsies.
Granada, AndalusiaAges 18 years+ - NCT06993402Enrolling by invitation
Düsseldorf ESD Study
This study is testing the use of ESD, a procedure to remove abnormal tissue from your digestive tract using a thin, flexible scope. It may be an option if you need this procedure in your esophagus, stomach, duodenum, colon, or rectum.
Düsseldorf, North Rhine-WestphaliaAges 18 years+ - NCT06990178Enrolling by invitation
Adaptive Neoadjuvant Therapy for Esophageal Cancer
This trial is testing a new treatment approach for esophageal cancer that includes chemotherapy and immunotherapy before surgery. The goal is to see if this combination can help shrink the tumor and improve outcomes.
Shenzhen, GuangdongAges 18–75 - NCT06987604Enrolling by invitation
Dialysis intensity for high ammonia in liver failure
This trial tests if a higher intensity of continuous dialysis (CRRT) better lowers ammonia levels in patients with liver failure. It aims to find the best approach to reduce brain complications from high ammonia.
Porto Alegre, Rio Grande do SulAges 18 years+ - NCT06985277Enrolling by invitation
Urgent endoscopy for maroon or bloody stools
This trial tests if a quick endoscopic exam of the upper digestive tract helps people who come to the hospital with maroon-colored or bloody stools. It may find the source of bleeding and guide treatment.
Bangkok, BangkokAges 18 years+ - NCT06984055Enrolling by invitation
Seeing esophageal cell changes with a special endoscope
This study tests a special endoscope that gives a close-up view of esophageal cells, to see if it can accurately spot early cancers or pre-cancerous changes. If you are already scheduled for a standard procedure or have a detected spot in your esophagus, this might help guide your treatment.
Shanghai, Shanghai MunicipalityAges 18–85 - NCT06976099Enrolling by invitation
Studying pancreatitis caused by high triglycerides
This study looks at people with acute pancreatitis caused by very high blood fat levels (triglycerides). It aims to collect information to better understand and treat this condition.
Beijing, Beijing MunicipalityAges 18–80
Common questions
- How many digestive system clinical trials are recruiting?
- Clin2 is tracking 7,916 recruiting gastroenterology studies from the U.S. registry right now, out of 12,516 we cover in this area in total.
- What does “Digestive system” cover here?
- Conditions of the stomach, intestines, liver, and the rest of the digestive tract. We group each study into digestive system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a digestive system trial near me?
- Use the search to filter digestive system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.